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The map label for this gene is echA17 [H]

Identifier: 21241998

GI number: 21241998

Start: 1420455

End: 1421225

Strand: Reverse

Name: echA17 [H]

Synonym: XAC1244

Alternate gene names: 21241998

Gene position: 1421225-1420455 (Counterclockwise)

Preceding gene: 21242000

Following gene: 21241997

Centisome position: 27.46

GC content: 68.87

Gene sequence:

>771_bases
ATGAGCATTCAGATCTTAGACCATGGCCGTCTTCGCGAAATCCGTCTGGCGCGTCCGCCGGTCAATGCGCTGGACAGCGC
GGTGTGCCAGGCGTTGAGCGTTGCGGTGCAGCAGGCCGGCGAGGAGGTCGACGGCATCGTACTGTCGGGCAGTGAGCGGA
TTTTTTCCGGCGGCATGGATGTGCCGCATCTGCTGGCCCATGGCGCCGACCGCGCTGCGCTGCTGGCCAGTTGGACCGCG
TTCTTCGATGCGGCGCAGGCGCTGGCCAACAGCCGCGTGCCGGTGGTCGCGGCCATCGGCGGGCATGCGCCGGCCGGCGG
CTGCGTGCTGGCGCTGTGCTGCGACTACCGGGTGATGGCGCGCAGCGCCGATACCGCAAGACCCTATACGATTGGCCTCA
ACGAAGTGCAGGTTGGCCTTGCTGCGCCGGAGGGTATCCAACGCCTGTTGCGCCGCGTGGTGGGTGCGCACCGCGCCGAA
CGCCTGCTGATCTCCGGGCAACTGCTGCCGGCCGAACAGGCGGTCGCGATCGGGCTGGTGGACGAACTGGTCGATGGCGA
GCTGGTCACCGCGCGCGCGGTGGCGTGGCTGCAGGAGCTGCAGCAGCTTCCCCGCCAACCGATGTTGACCACGCGCGCGA
TTGCGCGCGCCGACCTGCGCGCGGCATTGGCGCCGGAGTTGATCCAGCTGGAGCGCTTCATCGATGGCTGGTACGCGCCG
GATGCGCAGACCGCGCTGCATGGCCTGGTGGCGCGCCTGCAAAAGGCCTGA

Upstream 100 bases:

>100_bases
GCACTTGCCGCCAGCCCAAACGCCGCGAGCAACACGCCGGCATACCTAACCCGCCTGCTTCGACTGCCGTCTATCATGAC
CCGACCTCCAGGAGCCCCGA

Downstream 100 bases:

>100_bases
GCCCTGCCGTCGCGGCGCCCCTCGGGCGGGCCGGTATACTCGCTGTCCGTCGCATGCCCAGGCCAGCCTCTTGTCCGCCA
CCGCCGAACCCGTCGTCTCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MSIQILDHGRLREIRLARPPVNALDSAVCQALSVAVQQAGEEVDGIVLSGSERIFSGGMDVPHLLAHGADRAALLASWTA
FFDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMARSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAE
RLLISGQLLPAEQAVAIGLVDELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAP
DAQTALHGLVARLQKA

Sequences:

>Translated_256_residues
MSIQILDHGRLREIRLARPPVNALDSAVCQALSVAVQQAGEEVDGIVLSGSERIFSGGMDVPHLLAHGADRAALLASWTA
FFDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMARSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAE
RLLISGQLLPAEQAVAIGLVDELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAP
DAQTALHGLVARLQKA
>Mature_255_residues
SIQILDHGRLREIRLARPPVNALDSAVCQALSVAVQQAGEEVDGIVLSGSERIFSGGMDVPHLLAHGADRAALLASWTAF
FDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMARSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAER
LLISGQLLPAEQAVAIGLVDELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAPD
AQTALHGLVARLQKA

Specific function: Could possibly oxidize fatty acids using specific components [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI62530384, Length=251, Percent_Identity=30.6772908366534, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI295842266, Length=251, Percent_Identity=26.6932270916335, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI68989263, Length=199, Percent_Identity=31.6582914572864, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI194097323, Length=250, Percent_Identity=25.6, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI1790281, Length=183, Percent_Identity=30.6010928961749, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787659, Length=186, Percent_Identity=30.1075268817204, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17554946, Length=187, Percent_Identity=27.807486631016, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583165, Length=258, Percent_Identity=32.9457364341085, Blast_Score=128, Evalue=3e-30,
Organism=Drosophila melanogaster, GI19921018, Length=189, Percent_Identity=32.8042328042328, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI45550169, Length=257, Percent_Identity=28.7937743190661, Blast_Score=98, Evalue=5e-21,
Organism=Drosophila melanogaster, GI20129971, Length=187, Percent_Identity=29.9465240641711, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24653477, Length=187, Percent_Identity=29.9465240641711, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001753 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.17 [H]

Molecular weight: Translated: 27243; Mature: 27112

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIQILDHGRLREIRLARPPVNALDSAVCQALSVAVQQAGEEVDGIVLSGSERIFSGGMD
CEEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHCCEEEECCCHHHCCCCC
VPHLLAHGADRAALLASWTAFFDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
RSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAERLLISGQLLPAEQAVAIGLV
CCCCCCCCEEECHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
DELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAP
HHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DAQTALHGLVARLQKA
CHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIQILDHGRLREIRLARPPVNALDSAVCQALSVAVQQAGEEVDGIVLSGSERIFSGGMD
EEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCHHCCEEEECCCHHHCCCCC
VPHLLAHGADRAALLASWTAFFDAAQALANSRVPVVAAIGGHAPAGGCVLALCCDYRVMA
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHHHHH
RSADTARPYTIGLNEVQVGLAAPEGIQRLLRRVVGAHRAERLLISGQLLPAEQAVAIGLV
CCCCCCCCEEECHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
DELVDGELVTARAVAWLQELQQLPRQPMLTTRAIARADLRAALAPELIQLERFIDGWYAP
HHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
DAQTALHGLVARLQKA
CHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA