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The map label for this gene is colR [H]

Identifier: 21241975

GI number: 21241975

Start: 1401059

End: 1401775

Strand: Direct

Name: colR [H]

Synonym: XAC1221

Alternate gene names: 21241975

Gene position: 1401059-1401775 (Clockwise)

Preceding gene: 21241970

Following gene: 21241976

Centisome position: 27.07

GC content: 65.69

Gene sequence:

>717_bases
ATGCGGCTGCTGGTCATTGAAGACAACCGCAATATGGTTGCCAACCTGTTCGACTATTTCGAAGCGCGCGGGCATACCCT
GGACGCTGCGCCCGATGGCGTCACCGGCCTGCATCTGGCGACCACCCAGCATTACGACGCGTTGATCCTGGACTGGATGA
TGCCGCGCATGGATGGACCGGAAGTGCTGCGCCGGCTGCGTGAGCAGCACCAGTCCGAACTGCCGGTGATCATGCTCACC
GCACGCGACGAACTTCCGGACAAGATCGCCGGTTTCCGCGCCGGCGCCGACGACTACCTGACCAAACCCTTCGCGTTGCC
CGAGCTGGAGGTGCGCATCGAAGCCTTGCTGGCGCGTGCGCACGGCCGTCGCCGCGGCAAACTGCTGCAAGTGGCCGACC
TGCGCCTGGATCTGGCCACCCTGGAAGCGACGCGCGCCGGACAGGTGCTGCATCTGTATCCGGCCTGCCGCAAGTTGCTG
GAAGTGCTCATGCAGGCCAGCCCGGCCGCGGTGACGCGGCAACGCCTGGAGCAATCGTTGTGGGGCGACGACCCGCCCGA
CGGCGACATGCTGCGCTCGCATATCTACGAGTTGCGCCGCAGTGTGGACGGCCCGTTCGCGCAAAAATTGATCCATACCT
TGCCGCGGCTCGGCTACCGGCTGGCGCAGCTGGATGCGGCCGATGCGCCTGGCGCTGGCGACTGCAGCGATGTCTAA

Upstream 100 bases:

>100_bases
CAACCGATTGGAAGGCCGTACCGGCGATGCCGGTCGCGTTTGGCCGGCCTCGGTTAGGATGCGCACACCGTGCCTGCCGG
GCCGTCCTGGAAACCCGCTC

Downstream 100 bases:

>100_bases
ACAGCGCCCGTTGGGTCGCCGCGTGCTGGTGTGGTTGTTCGGCTACACGCTGTTGATGACCCTGGCGGTGTTCGGCACCG
CGCAGTACCTGCACGAACGT

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MRLLVIEDNRNMVANLFDYFEARGHTLDAAPDGVTGLHLATTQHYDALILDWMMPRMDGPEVLRRLREQHQSELPVIMLT
ARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARAHGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLL
EVLMQASPAAVTRQRLEQSLWGDDPPDGDMLRSHIYELRRSVDGPFAQKLIHTLPRLGYRLAQLDAADAPGAGDCSDV

Sequences:

>Translated_238_residues
MRLLVIEDNRNMVANLFDYFEARGHTLDAAPDGVTGLHLATTQHYDALILDWMMPRMDGPEVLRRLREQHQSELPVIMLT
ARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARAHGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLL
EVLMQASPAAVTRQRLEQSLWGDDPPDGDMLRSHIYELRRSVDGPFAQKLIHTLPRLGYRLAQLDAADAPGAGDCSDV
>Mature_238_residues
MRLLVIEDNRNMVANLFDYFEARGHTLDAAPDGVTGLHLATTQHYDALILDWMMPRMDGPEVLRRLREQHQSELPVIMLT
ARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARAHGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLL
EVLMQASPAAVTRQRLEQSLWGDDPPDGDMLRSHIYELRRSVDGPFAQKLIHTLPRLGYRLAQLDAADAPGAGDCSDV

Specific function: Member of the two-component regulatory system irlR/irlS. May be involved in invasion of eukaryotic cells and heavy-metal resistance [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=37.0535714285714, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1786784, Length=222, Percent_Identity=33.7837837837838, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1790552, Length=223, Percent_Identity=35.4260089686099, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI1786599, Length=223, Percent_Identity=29.5964125560538, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=30.3571428571429, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=33.7837837837838, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=31.1111111111111, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367329, Length=209, Percent_Identity=34.9282296650718, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=30.7017543859649, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1788550, Length=214, Percent_Identity=28.0373831775701, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1788713, Length=98, Percent_Identity=42.8571428571429, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1787229, Length=180, Percent_Identity=29.4444444444444, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1790860, Length=197, Percent_Identity=29.4416243654822, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790863, Length=118, Percent_Identity=36.4406779661017, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788191, Length=123, Percent_Identity=34.9593495934959, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR006291
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26703; Mature: 26703

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLLVIEDNRNMVANLFDYFEARGHTLDAAPDGVTGLHLATTQHYDALILDWMMPRMDGP
CEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCH
EVLRRLREQHQSELPVIMLTARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARA
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
HGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLLEVLMQASPAAVTRQRLEQSL
HCHHCCCEEEHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
WGDDPPDGDMLRSHIYELRRSVDGPFAQKLIHTLPRLGYRLAQLDAADAPGAGDCSDV
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLLVIEDNRNMVANLFDYFEARGHTLDAAPDGVTGLHLATTQHYDALILDWMMPRMDGP
CEEEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHCCCCCH
EVLRRLREQHQSELPVIMLTARDELPDKIAGFRAGADDYLTKPFALPELEVRIEALLARA
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHCCCCCHHHHCCCCCCCHHHHHHHHHHHHH
HGRRRGKLLQVADLRLDLATLEATRAGQVLHLYPACRKLLEVLMQASPAAVTRQRLEQSL
HCHHCCCEEEHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
WGDDPPDGDMLRSHIYELRRSVDGPFAQKLIHTLPRLGYRLAQLDAADAPGAGDCSDV
CCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9393784 [H]