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The map label for this gene is yjdB [H]

Identifier: 21241972

GI number: 21241972

Start: 1396581

End: 1398248

Strand: Reverse

Name: yjdB [H]

Synonym: XAC1218

Alternate gene names: 21241972

Gene position: 1398248-1396581 (Counterclockwise)

Preceding gene: 21241973

Following gene: 21241971

Centisome position: 27.02

GC content: 62.95

Gene sequence:

>1668_bases
ATGAGTACCTGGTTGCCGGAACCGCGCAAGCGTAGTGGCCTGCGCGCGCTGACATGGAGTACGCGGCCGACGGTGTCGAC
CGAAGCGCTGGTGCTGCTGTCGAGCCTGTTTTTTGCGTTGGCGTGCAATCAGTTGTTCTGGCGCACGGCCATGGCCACGC
ATCCGGGCAGCATCGGGTTTGCGATCTCGTTGATGGCGCTGCTGGTGGCCGTGCATGCGCTGCTCCTGGGCGTTTTGGTC
TGGCGCTGGAATGCAAAGCCGCTGCTGACGCTGTTGCTGTTCACCACCGCCCTGGCCGCGCACTACATGGACAGCTACAA
CGTCTATCTGGATGCGGACATGCTGCGCAACGTGCTGCATACCGATCACAAGGAATCGCGCGAGTTGCTCACGCCGGGCC
TGATCCTGCCGCTGGTGTGCTATTTCCTGATTCCGACCGCATTGCTGTGGCGCACGCGTTTGCGCGCACGCAGCGTGGGC
AAGACGGTGCTGGCGCGATCGGGTTTCCTGCTGGTGGTGGCGGTGGTCGGCGCTGCCGGCGCCATGCTCTCCTCGCAGGA
TATTTCGGCATTGATGCGCAATCACCGCGAAGTGCGTTATTTGGCCACGCCGATCAATTACATCGTGGCATTGCGGCAAA
ACCTCAAATCAGAATCGCCGATCAAGCGCGCGCCCAAACAGCCGATCGAACACGACGCCACGGCAACACCGCGCGCGCCG
GGGAGCCGCCCGCGCCTGTTGCTGGTGGTGCTGGGCGAAACCGCACGCGCGCAGAACTGGGGTCTCAACGGCTATGGCCG
CCAGACCACGCCGGAGCTGGCGCAGGCAGGGGTGATCAATTTCCCCGACATGCATTCGTGCGGGACCAGCACCGAGGTCT
CGGTGCCCTGCATGTTCTCCCCCTACGGCCGTCGCGATTACAACGAAGACATGATCCGTGGCCATCAGTCGTTCCTGCAT
GTACTGGAGCACGCTGGCATTTCGACGTTGTGGCGCGACAACCAGTCCGGCTGCAAGGGCGTGTGCGACGGGTTGGAGAT
CCAGAAGCTGGACGATGCCACCACACCAGGCCTGTGCGCCGATGGCCGCTGCATGGACGAGATCCTGCTGAGCGATCTGG
CTGCACAGGTGCGCGCAAAACCTGGCGACCGCGTGGTGGTGCTGCATCAACTGGGCAGCCATGGCCCGAGCTACTTCGAG
CGGTACCCGGCGCAATTCGAACGCTTCAAATCGGTGTGCAAGACCGCGGATCTGGGCAGCTGCGGCCGCCAGGACATCGT
CAACGCCTACGACAATTCGATCCTGTACACCGACCATTTCCTCAATCAGGCCATCCATGCGCTGCGCGGCCTGCCGGACT
ACGACACAGCGATGATCTATCTCTCCGATCATGGCGAATCGCTCGGTGAAAAAGGCCTGTACCTGCACGGCGTCCCGTAC
GCCATCGCGCCCAAGGAGCAGACCCATGTGCCGATGGTGATGTGGTTCTCGCCCGAGTTCGCGCGCGATCGCGGCCTGGA
TGAAGCCTGCCTGCGCCACCGTGCAGGGCAATACACCGATCAGGATGCGCTGTTCCCATCCGTGCTTGGGTTGATGCAGG
TCAAGACCAGCGTCTATGCGCCCGAGCGCGACCTGTTCGCCAAATGCACCGGCACCACGCTGCGCTGA

Upstream 100 bases:

>100_bases
CGCTGGCGGTGTGCTGGGTGAGCGCACTGGCGCTGTACTGCGTGATGCTGCAAAAGCCGCGTCGCGCGCTTGGATTGATG
TTGCCCTTGGGGGATGCAGC

Downstream 100 bases:

>100_bases
TCGCCAACGCCTGCCCCTGCCCGCCCCATCGCATGCGTGGCGGGCGCTGCCCCTTGCCCTGAAACCCGGCGCGCTCTAGC
CTTCGGCGGACTTCACTGCA

Product: inner membrane protein

Products: NA

Alternate protein names: Polymyxin resistance protein pmrC [H]

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSTWLPEPRKRSGLRALTWSTRPTVSTEALVLLSSLFFALACNQLFWRTAMATHPGSIGFAISLMALLVAVHALLLGVLV
WRWNAKPLLTLLLFTTALAAHYMDSYNVYLDADMLRNVLHTDHKESRELLTPGLILPLVCYFLIPTALLWRTRLRARSVG
KTVLARSGFLLVVAVVGAAGAMLSSQDISALMRNHREVRYLATPINYIVALRQNLKSESPIKRAPKQPIEHDATATPRAP
GSRPRLLLVVLGETARAQNWGLNGYGRQTTPELAQAGVINFPDMHSCGTSTEVSVPCMFSPYGRRDYNEDMIRGHQSFLH
VLEHAGISTLWRDNQSGCKGVCDGLEIQKLDDATTPGLCADGRCMDEILLSDLAAQVRAKPGDRVVVLHQLGSHGPSYFE
RYPAQFERFKSVCKTADLGSCGRQDIVNAYDNSILYTDHFLNQAIHALRGLPDYDTAMIYLSDHGESLGEKGLYLHGVPY
AIAPKEQTHVPMVMWFSPEFARDRGLDEACLRHRAGQYTDQDALFPSVLGLMQVKTSVYAPERDLFAKCTGTTLR

Sequences:

>Translated_555_residues
MSTWLPEPRKRSGLRALTWSTRPTVSTEALVLLSSLFFALACNQLFWRTAMATHPGSIGFAISLMALLVAVHALLLGVLV
WRWNAKPLLTLLLFTTALAAHYMDSYNVYLDADMLRNVLHTDHKESRELLTPGLILPLVCYFLIPTALLWRTRLRARSVG
KTVLARSGFLLVVAVVGAAGAMLSSQDISALMRNHREVRYLATPINYIVALRQNLKSESPIKRAPKQPIEHDATATPRAP
GSRPRLLLVVLGETARAQNWGLNGYGRQTTPELAQAGVINFPDMHSCGTSTEVSVPCMFSPYGRRDYNEDMIRGHQSFLH
VLEHAGISTLWRDNQSGCKGVCDGLEIQKLDDATTPGLCADGRCMDEILLSDLAAQVRAKPGDRVVVLHQLGSHGPSYFE
RYPAQFERFKSVCKTADLGSCGRQDIVNAYDNSILYTDHFLNQAIHALRGLPDYDTAMIYLSDHGESLGEKGLYLHGVPY
AIAPKEQTHVPMVMWFSPEFARDRGLDEACLRHRAGQYTDQDALFPSVLGLMQVKTSVYAPERDLFAKCTGTTLR
>Mature_554_residues
STWLPEPRKRSGLRALTWSTRPTVSTEALVLLSSLFFALACNQLFWRTAMATHPGSIGFAISLMALLVAVHALLLGVLVW
RWNAKPLLTLLLFTTALAAHYMDSYNVYLDADMLRNVLHTDHKESRELLTPGLILPLVCYFLIPTALLWRTRLRARSVGK
TVLARSGFLLVVAVVGAAGAMLSSQDISALMRNHREVRYLATPINYIVALRQNLKSESPIKRAPKQPIEHDATATPRAPG
SRPRLLLVVLGETARAQNWGLNGYGRQTTPELAQAGVINFPDMHSCGTSTEVSVPCMFSPYGRRDYNEDMIRGHQSFLHV
LEHAGISTLWRDNQSGCKGVCDGLEIQKLDDATTPGLCADGRCMDEILLSDLAAQVRAKPGDRVVVLHQLGSHGPSYFER
YPAQFERFKSVCKTADLGSCGRQDIVNAYDNSILYTDHFLNQAIHALRGLPDYDTAMIYLSDHGESLGEKGLYLHGVPYA
IAPKEQTHVPMVMWFSPEFARDRGLDEACLRHRAGQYTDQDALFPSVLGLMQVKTSVYAPERDLFAKCTGTTLR

Specific function: Catalyzes the addition of a phosphoethanolamine moiety to the lipid A. The phosphoethanolamine modification is required for resistance to polymyxin [H]

COG id: COG2194

COG function: function code R; Predicted membrane-associated, metal-dependent hydrolase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoethanolamine transferase family. EptA subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082372, Length=537, Percent_Identity=36.1266294227188, Blast_Score=356, Evalue=2e-99,
Organism=Escherichia coli, GI87082286, Length=444, Percent_Identity=29.0540540540541, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI87082223, Length=401, Percent_Identity=26.1845386533666, Blast_Score=86, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR012549
- InterPro:   IPR000917 [H]

Pfam domain/function: PF08019 DUF1705; PF00884 Sulfatase [H]

EC number: NA

Molecular weight: Translated: 61606; Mature: 61475

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTWLPEPRKRSGLRALTWSTRPTVSTEALVLLSSLFFALACNQLFWRTAMATHPGSIGF
CCCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AISLMALLVAVHALLLGVLVWRWNAKPLLTLLLFTTALAAHYMDSYNVYLDADMLRNVLH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHH
TDHKESRELLTPGLILPLVCYFLIPTALLWRTRLRARSVGKTVLARSGFLLVVAVVGAAG
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AMLSSQDISALMRNHREVRYLATPINYIVALRQNLKSESPIKRAPKQPIEHDATATPRAP
HHHCHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCC
GSRPRLLLVVLGETARAQNWGLNGYGRQTTPELAQAGVINFPDMHSCGTSTEVSVPCMFS
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEC
PYGRRDYNEDMIRGHQSFLHVLEHAGISTLWRDNQSGCKGVCDGLEIQKLDDATTPGLCA
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCCEEECCCCCCCCCCC
DGRCMDEILLSDLAAQVRAKPGDRVVVLHQLGSHGPSYFERYPAQFERFKSVCKTADLGS
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHCHHHHHHHHHHHHCCCCCC
CGRQDIVNAYDNSILYTDHFLNQAIHALRGLPDYDTAMIYLSDHGESLGEKGLYLHGVPY
CCHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEECCCE
AIAPKEQTHVPMVMWFSPEFARDRGLDEACLRHRAGQYTDQDALFPSVLGLMQVKTSVYA
EECCCCCCCCCEEEEECCHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
PERDLFAKCTGTTLR
CCHHHHHHCCCCCCC
>Mature Secondary Structure 
STWLPEPRKRSGLRALTWSTRPTVSTEALVLLSSLFFALACNQLFWRTAMATHPGSIGF
CCCCCCHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AISLMALLVAVHALLLGVLVWRWNAKPLLTLLLFTTALAAHYMDSYNVYLDADMLRNVLH
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHH
TDHKESRELLTPGLILPLVCYFLIPTALLWRTRLRARSVGKTVLARSGFLLVVAVVGAAG
CCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
AMLSSQDISALMRNHREVRYLATPINYIVALRQNLKSESPIKRAPKQPIEHDATATPRAP
HHHCHHHHHHHHHCCCHHEEHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCCCC
GSRPRLLLVVLGETARAQNWGLNGYGRQTTPELAQAGVINFPDMHSCGTSTEVSVPCMFS
CCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCEEEC
PYGRRDYNEDMIRGHQSFLHVLEHAGISTLWRDNQSGCKGVCDGLEIQKLDDATTPGLCA
CCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCCEEECCCCCCCCCCC
DGRCMDEILLSDLAAQVRAKPGDRVVVLHQLGSHGPSYFERYPAQFERFKSVCKTADLGS
CCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHCHHHHHHHHHHHHCCCCCC
CGRQDIVNAYDNSILYTDHFLNQAIHALRGLPDYDTAMIYLSDHGESLGEKGLYLHGVPY
CCHHHHHHHHCCCEEEHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCEEEECCCE
AIAPKEQTHVPMVMWFSPEFARDRGLDEACLRHRAGQYTDQDALFPSVLGLMQVKTSVYA
EECCCCCCCCCEEEEECCHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
PERDLFAKCTGTTLR
CCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8391535; 11677609 [H]