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The map label for this gene is clpX [H]

Identifier: 21241839

GI number: 21241839

Start: 1233615

End: 1234901

Strand: Direct

Name: clpX [H]

Synonym: XAC1079

Alternate gene names: 21241839

Gene position: 1233615-1234901 (Clockwise)

Preceding gene: 21241838

Following gene: 21241840

Centisome position: 23.84

GC content: 61.23

Gene sequence:

>1287_bases
ATGAGCGAAGACCGCCAAGGTCGTTCCGGCGACAGCAACAAGATTCTCTACTGCTCGTTCTGCGGTAAGAGTCAGCATGA
AGTCCGTAAGCTGATTGCCGGTCCCAGCGTATTCATCTGCGATGAGTGCGTTGAGCTGTGCAACGACATCATCCGCGAGG
AACTCGAAGAGAAGGCGCAGTCGGCACGGTCCAGCCTGCCCAAGCCGCGCGAGATTCTCGAGGTACTGGATCAATACGTG
ATCGGGCAGCTGCGCGCCAAGCGTACGCTCGCGGTAGCGGTGTACAACCACTACAAGCGTATCGAGAGCCGCAGCAAGAA
CGATGATGTGGAGCTGGCGAAATCCAACATCCTGCTGGTCGGCCCGACCGGGTCGGGCAAAACCCTGCTGGCCGAAACGC
TGGCGCGGCTGCTCAATGTGCCGTTCACGATCGCCGATGCCACCACGCTCACCGAAGCCGGCTATGTCGGCGAGGACGTG
GAAAACATCATCCAGAAGCTGTTGCAGAAGTGCGATTACGACGTCGAAAAGGCGCAGCAGGGCATCGTCTACATCGACGA
GATCGACAAGATCTCGCGCAAGAGCGAGAACCCGTCGATCACCCGCGATGTGTCCGGTGAAGGCGTGCAGCAGGCGCTGC
TCAAGCTGATCGAGGGCACGGTTGCCTCGGTGCCGCCGCAGGGCGGCCGCAAGCACCCGCAGCAGGAATTCCTGCAGGTC
GACACCAAGAACATCCTGTTCATCTGCGGCGGCGCATTCGCCGGCCTGGACAAGGTGATCCAGCAGCGTTCCAACGACGC
TGGTGGCATCGGCTTCGGCGCCAAGGTCAAGAGCAGCGAGCGCAAGCAGGAAGTGGGCAAGATCCTGGCCGAAGTCGAGC
CGGAAGATCTGATCAAGTTCGGCCTGATTCCCGAGTTCGTCGGCCGTCTGCCGGTGGTCGCCACGCTCGAAGAGCTGGAC
GAGCCGGCGTTGATCAAGATCCTGACCGAGCCCAAGAACGCCATCACCAAACAGTTCAAGAAGCTGTTCGACATGGAAGG
TGTGGAGCTGGAGTTCCGCCCCGACGCCCTGTCTGCGATCGCCAAGAAGGCGCTCAAGCGCAAGACCGGCGCGCGTGGCC
TGCGCACCATCGTCGAATCGGTGCTGCTGGACACGATGTACGAGCTGCCGTCGCAGGAAAACGTCAGCAAGGTGGTGGTG
GACGAGTCGGTGATCGAGCACAAATCCGAGCCGTATCTGATCTACCAGGCGCAACCGGCGCCGGCCAAGGCTGCGTCCGG
AGACTGA

Upstream 100 bases:

>100_bases
AAAAACCGGCAGGGTCGGGCGGGGCGAATGTCCTCCCGACCCTGTGCTATTCTCGAATCGAACCCCCGTGCATCGGGTGG
GGTAACTGGGTAACAGAAGC

Downstream 100 bases:

>100_bases
GTCCGTTGGCCGCCTCGCCAGGCCTCGGCCTCGCTGGCGGATAACCGCTTTCCTAACGCTACTTGCAACACCTCGCCGAT
GGCCCCATAACGGGGCCATC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSEDRQGRSGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSSLPKPREILEVLDQYV
IGQLRAKRTLAVAVYNHYKRIESRSKNDDVELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTKNILFICGGAFAGLDKVIQQRSNDAGGIGFGAKVKSSERKQEVGKILAEVEPEDLIKFGLIPEFVGRLPVVATLEELD
EPALIKILTEPKNAITKQFKKLFDMEGVELEFRPDALSAIAKKALKRKTGARGLRTIVESVLLDTMYELPSQENVSKVVV
DESVIEHKSEPYLIYQAQPAPAKAASGD

Sequences:

>Translated_428_residues
MSEDRQGRSGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSSLPKPREILEVLDQYV
IGQLRAKRTLAVAVYNHYKRIESRSKNDDVELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDV
ENIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
DTKNILFICGGAFAGLDKVIQQRSNDAGGIGFGAKVKSSERKQEVGKILAEVEPEDLIKFGLIPEFVGRLPVVATLEELD
EPALIKILTEPKNAITKQFKKLFDMEGVELEFRPDALSAIAKKALKRKTGARGLRTIVESVLLDTMYELPSQENVSKVVV
DESVIEHKSEPYLIYQAQPAPAKAASGD
>Mature_427_residues
SEDRQGRSGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQSARSSLPKPREILEVLDQYVI
GQLRAKRTLAVAVYNHYKRIESRSKNDDVELAKSNILLVGPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVE
NIIQKLLQKCDYDVEKAQQGIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQVD
TKNILFICGGAFAGLDKVIQQRSNDAGGIGFGAKVKSSERKQEVGKILAEVEPEDLIKFGLIPEFVGRLPVVATLEELDE
PALIKILTEPKNAITKQFKKLFDMEGVELEFRPDALSAIAKKALKRKTGARGLRTIVESVLLDTMYELPSQENVSKVVVD
ESVIEHKSEPYLIYQAQPAPAKAASGD

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=345, Percent_Identity=52.463768115942, Blast_Score=328, Evalue=7e-90,
Organism=Escherichia coli, GI1786642, Length=429, Percent_Identity=75.2913752913753, Blast_Score=646, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=101, Percent_Identity=46.5346534653465, Blast_Score=96, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=317, Percent_Identity=45.7413249211356, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=319, Percent_Identity=46.0815047021944, Blast_Score=275, Evalue=4e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=408, Percent_Identity=38.2352941176471, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71988660, Length=247, Percent_Identity=40.4858299595142, Blast_Score=174, Evalue=7e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=454, Percent_Identity=38.5462555066079, Blast_Score=278, Evalue=9e-76,
Organism=Drosophila melanogaster, GI24648291, Length=304, Percent_Identity=48.3552631578947, Blast_Score=291, Evalue=6e-79,
Organism=Drosophila melanogaster, GI24648289, Length=304, Percent_Identity=48.3552631578947, Blast_Score=291, Evalue=7e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 47136; Mature: 47004

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEDRQGRSGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQ
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
SARSSLPKPREILEVLDQYVIGQLRAKRTLAVAVYNHYKRIESRSKNDDVELAKSNILLV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEEE
GPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQ
ECCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CCEEEHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTKNILFICGGAFAGLDKVIQQRSNDAGGIGFGAKVKSSERKQEVGKILAEVEPEDLIKF
CCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
GLIPEFVGRLPVVATLEELDEPALIKILTEPKNAITKQFKKLFDMEGVELEFRPDALSAI
CCCHHHHCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHHHHH
AKKALKRKTGARGLRTIVESVLLDTMYELPSQENVSKVVVDESVIEHKSEPYLIYQAQPA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCC
PAKAASGD
CCCCCCCC
>Mature Secondary Structure 
SEDRQGRSGDSNKILYCSFCGKSQHEVRKLIAGPSVFICDECVELCNDIIREELEEKAQ
CCCCCCCCCCCCCEEEEEECCCCHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHH
SARSSLPKPREILEVLDQYVIGQLRAKRTLAVAVYNHYKRIESRSKNDDVELAKSNILLV
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCEEEE
GPTGSGKTLLAETLARLLNVPFTIADATTLTEAGYVGEDVENIIQKLLQKCDYDVEKAQQ
ECCCCCCHHHHHHHHHHHCCCEEEECHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHC
GIVYIDEIDKISRKSENPSITRDVSGEGVQQALLKLIEGTVASVPPQGGRKHPQQEFLQV
CCEEEHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCHHHCCCCCCCCCCCHHHHHHH
DTKNILFICGGAFAGLDKVIQQRSNDAGGIGFGAKVKSSERKQEVGKILAEVEPEDLIKF
CCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
GLIPEFVGRLPVVATLEELDEPALIKILTEPKNAITKQFKKLFDMEGVELEFRPDALSAI
CCCHHHHCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCCEEEECCHHHHHH
AKKALKRKTGARGLRTIVESVLLDTMYELPSQENVSKVVVDESVIEHKSEPYLIYQAQPA
HHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCC
PAKAASGD
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA