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The map label for this gene is ppx [H]

Identifier: 21241804

GI number: 21241804

Start: 1198091

End: 1199617

Strand: Reverse

Name: ppx [H]

Synonym: XAC1039

Alternate gene names: 21241804

Gene position: 1199617-1198091 (Counterclockwise)

Preceding gene: 21241805

Following gene: 21241803

Centisome position: 23.18

GC content: 65.62

Gene sequence:

>1527_bases
ATGCCAATGCCCTCCCCCACGATTCCGCCCCTGCGCGATGGCGATTTTCTCGCCGCCATCGACCTAGGCTCCAACAGTTT
CCACATGGTCATTGCGCGCTACCTGATGGGTCAGCTGCGTGTCGTCGATCGCCTGCGCGAGACCGTGCGCATGGCCGATG
GCCTGGATGGCAAAGGTGGGCTCTCCAACGAAGCGCGTCAGCGCGCACTGGAATGCCTGGCGCGGTTTGGCCAGCGCATT
CGCGACGTGCCTTCGCTACGCGTGCGCGCGCTAGCGACCAACACGGTGCGTCAGCTGCGTTCGCCGCAAGCGTTTTTGAT
GCCGGCCGAAACCGCGCTGGGTCATGCGATCGAAGTGGTCAGCGGGCGCGAGGAAGCACGCCTGATCTATCTGGGCGTGG
CGCATGCGCAACCGCCCAAGCCCGACCAACGCCGGCTGGTGATCGACATCGGCGGCGGCTCGACCGAGTTCATCATCGGC
CGCGGGTTTCAGACGCTGGAACGCGAGAGTCTGCAGGCCGGATGCATTGCCAGCACGCGGCGGTTTTTCCCGGGCGGCAA
ATTGTCGAAGAAGAAATGGAAGGACGCGCTGACCGAGATCGGCGCCGAGTTCCAGCAGTTCGCCGGCCAGTACAAGGCGC
TGGGCTGGCATGAGGCGATCGGCTCGTCCGGCACGCACAAGGCCATCGGCGAGATGTGCGCTGCAATGAAGCTGACCAAG
GGGGCGATCACGGCGCAGGCGCTGCCGGCGCTGCGCGAGGAGTTGCTCAAGGCCAAGCGCATCGAAGACATCCAGCTGCC
CGGTCTGGCCGCCGAACGGCGGCCCATCATCGCCGGTGGCATCTTGGTGCTGGAAGCTGCGTTCCAGGCGCTGGGGCTGG
AGAAACTGATGGTCAGCAAGGCGGCGATGCGCGAAGGCATCCTGTACGACATGCTTGGCCGCGGCGGCGAAAACGACCCG
CGCGACAGTTCGGTGACCTCGCTGATGCAACGCTACGGCATCGACGAAGTACAGGCGCAGCGCGTGGAAGCCACCGCCTG
CCGCCTGTTCGACCAGGTCTGCGAATCCTGGCAACTGGATGGCGACGACGCGCAGGTACTGCGCCGTGCCGCGCGACTGC
ACGAGCTGGGGCTGATCATTGCGCACAGCCAGTACCACGTGCACGGCAGCTACATCCTGGAACACTCGGATATCGCGGGT
TTTTCGCGGCAGGAACAGCAGGTGCTGGCCTCGCTGGTGCGCACGCACCGGCGCAATGTGCCCAAGACCGCCTTCGATGC
GCTGCCCGACCGCCTGCTGCTGCCGACCCGACGCAAGGCCGCACTGCTGCGACTGGCGGTGTTGCTGCACCGCGCGCATG
AGTCCGACCCGATCCCGACCCTGGAACTCACCGCCGACGACACCCGGTTGTCGTTGATCCTGTCGCAAAGCTGGATCGAC
TCGCGCCCGCTGCTGCGCGCCGACCTGATCGGCGAAGTCGACAGCATGGCCGGGCTGGGAATTGCGTTCAAACCGTTTGT
GACCTGA

Upstream 100 bases:

>100_bases
CGCCCGCCCCCAGCGCTTCCAATACCGAGCGCGTGCGCCTGCAGCTGGGCGCACGCATGGCCTCTCACGTGGCCAACAGC
CCATCGGCTACCATGCGGCC

Downstream 100 bases:

>100_bases
GGCCTGCGGCCTCAGGCGGGAATCGGGAATCGGGAATCGGGAATAGTCCGCCACGGGGCTCTTAGAAGTTTCTGAGTGGT
GTCGATGGCGCCGAACCGGT

Product: exopolyphosphatase

Products: NA

Alternate protein names: ExopolyPase; Metaphosphatase [H]

Number of amino acids: Translated: 508; Mature: 507

Protein sequence:

>508_residues
MPMPSPTIPPLRDGDFLAAIDLGSNSFHMVIARYLMGQLRVVDRLRETVRMADGLDGKGGLSNEARQRALECLARFGQRI
RDVPSLRVRALATNTVRQLRSPQAFLMPAETALGHAIEVVSGREEARLIYLGVAHAQPPKPDQRRLVIDIGGGSTEFIIG
RGFQTLERESLQAGCIASTRRFFPGGKLSKKKWKDALTEIGAEFQQFAGQYKALGWHEAIGSSGTHKAIGEMCAAMKLTK
GAITAQALPALREELLKAKRIEDIQLPGLAAERRPIIAGGILVLEAAFQALGLEKLMVSKAAMREGILYDMLGRGGENDP
RDSSVTSLMQRYGIDEVQAQRVEATACRLFDQVCESWQLDGDDAQVLRRAARLHELGLIIAHSQYHVHGSYILEHSDIAG
FSRQEQQVLASLVRTHRRNVPKTAFDALPDRLLLPTRRKAALLRLAVLLHRAHESDPIPTLELTADDTRLSLILSQSWID
SRPLLRADLIGEVDSMAGLGIAFKPFVT

Sequences:

>Translated_508_residues
MPMPSPTIPPLRDGDFLAAIDLGSNSFHMVIARYLMGQLRVVDRLRETVRMADGLDGKGGLSNEARQRALECLARFGQRI
RDVPSLRVRALATNTVRQLRSPQAFLMPAETALGHAIEVVSGREEARLIYLGVAHAQPPKPDQRRLVIDIGGGSTEFIIG
RGFQTLERESLQAGCIASTRRFFPGGKLSKKKWKDALTEIGAEFQQFAGQYKALGWHEAIGSSGTHKAIGEMCAAMKLTK
GAITAQALPALREELLKAKRIEDIQLPGLAAERRPIIAGGILVLEAAFQALGLEKLMVSKAAMREGILYDMLGRGGENDP
RDSSVTSLMQRYGIDEVQAQRVEATACRLFDQVCESWQLDGDDAQVLRRAARLHELGLIIAHSQYHVHGSYILEHSDIAG
FSRQEQQVLASLVRTHRRNVPKTAFDALPDRLLLPTRRKAALLRLAVLLHRAHESDPIPTLELTADDTRLSLILSQSWID
SRPLLRADLIGEVDSMAGLGIAFKPFVT
>Mature_507_residues
PMPSPTIPPLRDGDFLAAIDLGSNSFHMVIARYLMGQLRVVDRLRETVRMADGLDGKGGLSNEARQRALECLARFGQRIR
DVPSLRVRALATNTVRQLRSPQAFLMPAETALGHAIEVVSGREEARLIYLGVAHAQPPKPDQRRLVIDIGGGSTEFIIGR
GFQTLERESLQAGCIASTRRFFPGGKLSKKKWKDALTEIGAEFQQFAGQYKALGWHEAIGSSGTHKAIGEMCAAMKLTKG
AITAQALPALREELLKAKRIEDIQLPGLAAERRPIIAGGILVLEAAFQALGLEKLMVSKAAMREGILYDMLGRGGENDPR
DSSVTSLMQRYGIDEVQAQRVEATACRLFDQVCESWQLDGDDAQVLRRAARLHELGLIIAHSQYHVHGSYILEHSDIAGF
SRQEQQVLASLVRTHRRNVPKTAFDALPDRLLLPTRRKAALLRLAVLLHRAHESDPIPTLELTADDTRLSLILSQSWIDS
RPLLRADLIGEVDSMAGLGIAFKPFVT

Specific function: Degradation of inorganic polyphosphates. Orthophosphate is released progressively from the ends of polyphosphate [H]

COG id: COG0248

COG function: function code FP; Exopolyphosphatase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gppA/ppx family [H]

Homologues:

Organism=Escherichia coli, GI1788848, Length=494, Percent_Identity=38.8663967611336, Blast_Score=324, Evalue=9e-90,
Organism=Escherichia coli, GI48994966, Length=470, Percent_Identity=35.1063829787234, Blast_Score=287, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022371
- InterPro:   IPR003695 [H]

Pfam domain/function: PF02541 Ppx-GppA [H]

EC number: =3.6.1.11 [H]

Molecular weight: Translated: 55938; Mature: 55807

Theoretical pI: Translated: 9.37; Mature: 9.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPSPTIPPLRDGDFLAAIDLGSNSFHMVIARYLMGQLRVVDRLRETVRMADGLDGKGG
CCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSNEARQRALECLARFGQRIRDVPSLRVRALATNTVRQLRSPQAFLMPAETALGHAIEVV
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHH
SGREEARLIYLGVAHAQPPKPDQRRLVIDIGGGSTEFIIGRGFQTLERESLQAGCIASTR
CCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHH
RFFPGGKLSKKKWKDALTEIGAEFQQFAGQYKALGWHEAIGSSGTHKAIGEMCAAMKLTK
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHH
GAITAQALPALREELLKAKRIEDIQLPGLAAERRPIIAGGILVLEAAFQALGLEKLMVSK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
AAMREGILYDMLGRGGENDPRDSSVTSLMQRYGIDEVQAQRVEATACRLFDQVCESWQLD
HHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GDDAQVLRRAARLHELGLIIAHSQYHVHGSYILEHSDIAGFSRQEQQVLASLVRTHRRNV
CCHHHHHHHHHHHHHHCEEEEECEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
PKTAFDALPDRLLLPTRRKAALLRLAVLLHRAHESDPIPTLELTADDTRLSLILSQSWID
CHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEHHCCC
SRPLLRADLIGEVDSMAGLGIAFKPFVT
CCCCHHHHHHHHHHHHCCCCEECCCCCC
>Mature Secondary Structure 
PMPSPTIPPLRDGDFLAAIDLGSNSFHMVIARYLMGQLRVVDRLRETVRMADGLDGKGG
CCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
LSNEARQRALECLARFGQRIRDVPSLRVRALATNTVRQLRSPQAFLMPAETALGHAIEVV
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEECHHHHHHHHHHH
SGREEARLIYLGVAHAQPPKPDQRRLVIDIGGGSTEFIIGRGFQTLERESLQAGCIASTR
CCCCCCEEEEEEECCCCCCCCCCCEEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHH
RFFPGGKLSKKKWKDALTEIGAEFQQFAGQYKALGWHEAIGSSGTHKAIGEMCAAMKLTK
HCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHHHH
GAITAQALPALREELLKAKRIEDIQLPGLAAERRPIIAGGILVLEAAFQALGLEKLMVSK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
AAMREGILYDMLGRGGENDPRDSSVTSLMQRYGIDEVQAQRVEATACRLFDQVCESWQLD
HHHHCCHHHHHHCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCC
GDDAQVLRRAARLHELGLIIAHSQYHVHGSYILEHSDIAGFSRQEQQVLASLVRTHRRNV
CCHHHHHHHHHHHHHHCEEEEECEEEECCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCC
PKTAFDALPDRLLLPTRRKAALLRLAVLLHRAHESDPIPTLELTADDTRLSLILSQSWID
CHHHHHHCCCHHCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEEEEHHCCC
SRPLLRADLIGEVDSMAGLGIAFKPFVT
CCCCHHHHHHHHHHHHCCCCEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10382967; 10984043 [H]