BacMap

Definition	Xanthomonas axonopodis pv. citri str. 306 chromosome, complete genome.
Accession	NC_003919
Length	5,175,554

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The map label for this gene is ppiB [H]

Identifier: 21241770

GI number: 21241770

Start: 1160286

End: 1160780

Strand: Direct

Name: ppiB [H]

Synonym: XAC1005

Alternate gene names: 21241770

Gene position: 1160286-1160780 (Clockwise)

Preceding gene: 21241766

Following gene: 21241771

Centisome position: 22.42

GC content: 65.86

Gene sequence:

>495_bases
ATGTCCCTGATCGCCACTTTCGACACCTCCCGCGGCCCCATCGTCGTCGAGCTGTACCCGGACAAGGCCCCGCTGACGGT
TGCCAACTTCGTCAACCTGGCCAAGCGCGGCTTCTACAACGGCCTGAGCTTCCACCGCGTCATCGCCGACTTCATGATCC
AGGGCGGTTGCCCGGAAGGTTCCGGCCGCGGCGGCCCGGGCTACCGTTTCGAAGACGAGACCAACAATGGCGTCGGCCAC
GAGCGCGGCGTGCTGTCCATGGCCAATGCCGGCCCGAACACCAACGGCAGCCAGTTCTTCATCACCCACACCGCCACCCC
GTGGCTGGACGGCAAGCACACCGTGTTCGGCAAGGTCACCCAGGGCCTGGACGTGGTCGATAGCGTTGCCCAGGGCGACA
CCATCAATACCCTCACCATCGAAGGCGACACCGACGCCGTGCTGGCCGCCAAGGCCGACCGCGTTGCGGAGTGGAACAAG
ATCCTCGCCGCCTGA

Upstream 100 bases:

>100_bases
AGGCGGGAGCGTTGGACGATGGTCGTACCCATGCGGCCGGCCACGCACCCGGGTGTATCCTAGCGGGCTATTGATCACCC
CAGAACCTGCAAGGATTTCT

Downstream 100 bases:

>100_bases
TCGCATCCCGTCGAACGGCCGCCATGTGCGGCCGTTCGCTTGTCAATGCGCGCCGCCAGGCCTTGCGCCCCGCCAGCGTA
CGACCCTTACCAACGTTTTT

Product: peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 164; Mature: 163

Protein sequence:

>164_residues
MSLIATFDTSRGPIVVELYPDKAPLTVANFVNLAKRGFYNGLSFHRVIADFMIQGGCPEGSGRGGPGYRFEDETNNGVGH
ERGVLSMANAGPNTNGSQFFITHTATPWLDGKHTVFGKVTQGLDVVDSVAQGDTINTLTIEGDTDAVLAAKADRVAEWNK
ILAA

Sequences:

>Translated_164_residues
MSLIATFDTSRGPIVVELYPDKAPLTVANFVNLAKRGFYNGLSFHRVIADFMIQGGCPEGSGRGGPGYRFEDETNNGVGH
ERGVLSMANAGPNTNGSQFFITHTATPWLDGKHTVFGKVTQGLDVVDSVAQGDTINTLTIEGDTDAVLAAKADRVAEWNK
ILAA
>Mature_163_residues
SLIATFDTSRGPIVVELYPDKAPLTVANFVNLAKRGFYNGLSFHRVIADFMIQGGCPEGSGRGGPGYRFEDETNNGVGHE
RGVLSMANAGPNTNGSQFFITHTATPWLDGKHTVFGKVTQGLDVVDSVAQGDTINTLTIEGDTDAVLAAKADRVAEWNKI
LAA

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=132, Percent_Identity=56.0606060606061, Blast_Score=146, Evalue=9e-36,
Organism=Homo sapiens, GI24308049, Length=130, Percent_Identity=53.8461538461538, Blast_Score=137, Evalue=6e-33,
Organism=Homo sapiens, GI19557636, Length=133, Percent_Identity=48.8721804511278, Blast_Score=126, Evalue=1e-29,
Organism=Homo sapiens, GI10863927, Length=142, Percent_Identity=48.5915492957746, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI4758950, Length=134, Percent_Identity=50.7462686567164, Blast_Score=111, Evalue=3e-25,
Organism=Homo sapiens, GI4505991, Length=129, Percent_Identity=53.4883720930233, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI256017253, Length=135, Percent_Identity=45.9259259259259, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI221139811, Length=135, Percent_Identity=45.9259259259259, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI256017251, Length=135, Percent_Identity=45.9259259259259, Blast_Score=107, Evalue=7e-24,
Organism=Homo sapiens, GI5031987, Length=125, Percent_Identity=52, Blast_Score=106, Evalue=9e-24,
Organism=Homo sapiens, GI5174637, Length=130, Percent_Identity=51.5384615384615, Blast_Score=106, Evalue=1e-23,
Organism=Homo sapiens, GI45439316, Length=130, Percent_Identity=49.2307692307692, Blast_Score=105, Evalue=1e-23,
Organism=Homo sapiens, GI303305009, Length=126, Percent_Identity=50.7936507936508, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI22547212, Length=125, Percent_Identity=48, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI7657473, Length=125, Percent_Identity=48, Blast_Score=105, Evalue=2e-23,
Organism=Homo sapiens, GI178057341, Length=135, Percent_Identity=45.1851851851852, Blast_Score=104, Evalue=3e-23,
Organism=Homo sapiens, GI310127646, Length=149, Percent_Identity=42.2818791946309, Blast_Score=103, Evalue=6e-23,
Organism=Homo sapiens, GI310114371, Length=149, Percent_Identity=42.2818791946309, Blast_Score=103, Evalue=6e-23,
Organism=Homo sapiens, GI310119221, Length=149, Percent_Identity=42.2818791946309, Blast_Score=103, Evalue=6e-23,
Organism=Homo sapiens, GI4826932, Length=158, Percent_Identity=43.6708860759494, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI42560244, Length=146, Percent_Identity=43.8356164383562, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI22547215, Length=125, Percent_Identity=48, Blast_Score=102, Evalue=1e-22,
Organism=Homo sapiens, GI310129267, Length=151, Percent_Identity=43.046357615894, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI310120620, Length=151, Percent_Identity=43.046357615894, Blast_Score=102, Evalue=2e-22,
Organism=Homo sapiens, GI6631100, Length=134, Percent_Identity=44.7761194029851, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI209417936, Length=135, Percent_Identity=44.4444444444444, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI30102944, Length=135, Percent_Identity=44.4444444444444, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI219842199, Length=135, Percent_Identity=44.4444444444444, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI310110104, Length=136, Percent_Identity=44.1176470588235, Blast_Score=99, Evalue=2e-21,
Organism=Homo sapiens, GI64276486, Length=116, Percent_Identity=43.9655172413793, Blast_Score=97, Evalue=7e-21,
Organism=Homo sapiens, GI5454154, Length=130, Percent_Identity=46.1538461538462, Blast_Score=97, Evalue=9e-21,
Organism=Homo sapiens, GI20911035, Length=141, Percent_Identity=36.8794326241135, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI169164185, Length=141, Percent_Identity=42.5531914893617, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI169163623, Length=141, Percent_Identity=42.5531914893617, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI169163387, Length=141, Percent_Identity=42.5531914893617, Blast_Score=95, Evalue=3e-20,
Organism=Homo sapiens, GI310127745, Length=142, Percent_Identity=41.5492957746479, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI310119290, Length=142, Percent_Identity=41.5492957746479, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI310114540, Length=142, Percent_Identity=41.5492957746479, Blast_Score=90, Evalue=9e-19,
Organism=Homo sapiens, GI310132444, Length=142, Percent_Identity=41.5492957746479, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI310113152, Length=142, Percent_Identity=41.5492957746479, Blast_Score=89, Evalue=2e-18,
Organism=Homo sapiens, GI150418007, Length=126, Percent_Identity=46.031746031746, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI169214050, Length=142, Percent_Identity=40.8450704225352, Blast_Score=86, Evalue=2e-17,
Organism=Homo sapiens, GI239751853, Length=142, Percent_Identity=40.8450704225352, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI113428306, Length=142, Percent_Identity=40.8450704225352, Blast_Score=85, Evalue=3e-17,
Organism=Homo sapiens, GI27735045, Length=143, Percent_Identity=39.8601398601399, Blast_Score=84, Evalue=5e-17,
Organism=Homo sapiens, GI14277126, Length=75, Percent_Identity=56, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI289803023, Length=169, Percent_Identity=31.9526627218935, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786736, Length=136, Percent_Identity=39.7058823529412, Blast_Score=93, Evalue=7e-21,
Organism=Escherichia coli, GI1789763, Length=133, Percent_Identity=42.8571428571429, Blast_Score=93, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17539496, Length=134, Percent_Identity=56.7164179104478, Blast_Score=147, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17506311, Length=135, Percent_Identity=51.8518518518518, Blast_Score=126, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17532641, Length=130, Percent_Identity=46.1538461538462, Blast_Score=120, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17506307, Length=149, Percent_Identity=48.993288590604, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71980594, Length=131, Percent_Identity=46.5648854961832, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71980590, Length=131, Percent_Identity=46.5648854961832, Blast_Score=117, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17552780, Length=125, Percent_Identity=54.4, Blast_Score=117, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17559074, Length=134, Percent_Identity=50, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17566266, Length=132, Percent_Identity=50, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17552782, Length=132, Percent_Identity=48.4848484848485, Blast_Score=109, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI71997782, Length=121, Percent_Identity=44.6280991735537, Blast_Score=106, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17539498, Length=130, Percent_Identity=49.2307692307692, Blast_Score=106, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17565860, Length=134, Percent_Identity=45.5223880597015, Blast_Score=102, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI17552784, Length=133, Percent_Identity=43.609022556391, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17551282, Length=139, Percent_Identity=46.7625899280576, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17551284, Length=139, Percent_Identity=46.7625899280576, Blast_Score=96, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17532643, Length=131, Percent_Identity=46.5648854961832, Blast_Score=91, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI32563659, Length=143, Percent_Identity=34.965034965035, Blast_Score=87, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115533296, Length=130, Percent_Identity=36.9230769230769, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323562, Length=128, Percent_Identity=51.5625, Blast_Score=115, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320359, Length=126, Percent_Identity=55.5555555555556, Blast_Score=114, Evalue=8e-27,
Organism=Saccharomyces cerevisiae, GI6320510, Length=137, Percent_Identity=51.0948905109489, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321848, Length=164, Percent_Identity=43.2926829268293, Blast_Score=104, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6323246, Length=133, Percent_Identity=48.8721804511278, Blast_Score=100, Evalue=7e-23,
Organism=Saccharomyces cerevisiae, GI6322492, Length=157, Percent_Identity=37.5796178343949, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17986117, Length=135, Percent_Identity=54.0740740740741, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI19922376, Length=127, Percent_Identity=50.3937007874016, Blast_Score=134, Evalue=2e-32,
Organism=Drosophila melanogaster, GI19922912, Length=126, Percent_Identity=53.1746031746032, Blast_Score=113, Evalue=5e-26,
Organism=Drosophila melanogaster, GI20130249, Length=130, Percent_Identity=49.2307692307692, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI45549139, Length=126, Percent_Identity=52.3809523809524, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24652460, Length=130, Percent_Identity=41.5384615384615, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24664125, Length=150, Percent_Identity=46.6666666666667, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI21357783, Length=150, Percent_Identity=46.6666666666667, Blast_Score=103, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17647301, Length=127, Percent_Identity=48.8188976377953, Blast_Score=102, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21357249, Length=138, Percent_Identity=41.304347826087, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24650807, Length=130, Percent_Identity=46.1538461538462, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI17136360, Length=133, Percent_Identity=45.1127819548872, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24586038, Length=139, Percent_Identity=43.8848920863309, Blast_Score=91, Evalue=3e-19,
Organism=Drosophila melanogaster, GI21355677, Length=138, Percent_Identity=36.231884057971, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24661775, Length=155, Percent_Identity=34.1935483870968, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21355237, Length=155, Percent_Identity=34.1935483870968, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24661771, Length=155, Percent_Identity=34.1935483870968, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17457; Mature: 17326

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLIATFDTSRGPIVVELYPDKAPLTVANFVNLAKRGFYNGLSFHRVIADFMIQGGCPEG
CCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
SGRGGPGYRFEDETNNGVGHERGVLSMANAGPNTNGSQFFITHTATPWLDGKHTVFGKVT
CCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHH
QGLDVVDSVAQGDTINTLTIEGDTDAVLAAKADRVAEWNKILAA
CCHHHHHHHHCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SLIATFDTSRGPIVVELYPDKAPLTVANFVNLAKRGFYNGLSFHRVIADFMIQGGCPEG
CEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCC
SGRGGPGYRFEDETNNGVGHERGVLSMANAGPNTNGSQFFITHTATPWLDGKHTVFGKVT
CCCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEECCCCCCCCCEEEEEHHH
QGLDVVDSVAQGDTINTLTIEGDTDAVLAAKADRVAEWNKILAA
CCHHHHHHHHCCCCEEEEEEECCCCEEEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9317025; 9665876 [H]