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The map label for this gene is gfo [H]

Identifier: 21241658

GI number: 21241658

Start: 1049347

End: 1050483

Strand: Direct

Name: gfo [H]

Synonym: XAC0888

Alternate gene names: 21241658

Gene position: 1049347-1050483 (Clockwise)

Preceding gene: 21241650

Following gene: 21241664

Centisome position: 20.28

GC content: 62.18

Gene sequence:

>1137_bases
ATGCCCACACTCGCGAAGGAGGTTTGCATGTCCGTGGAATCGATCACACGTCGCCGCTTGCTTGCCGCCTTTGGCGGTGC
AGGCATCCTGCTCGCTGCACCGACGTGGGCAGTGCCAAAGAAAAAGCCCGGAAAACCGCTCAATGTCGCGTTGGTCGGGT
TGGGTAGTTATGCCAGCGAACAGCTCGCGCCCGGTCTGGCGCTGACCAAGCATTGCAAGCTCGCCGGTATCGTCACCGGC
ACGCCGTCGAAGATTCCGCAGTGGCAGTCCAAGTACGGCATCGCCGACCGCAATGTCTACAGCTACGAGAACTTCGATCG
CATCGCCGACAACGACGACATCGATGTGGTGTACATCGTCACGCCCACGCATCTGCATGCGCCACTGACCCTGCGTGCGG
CTGCCGCAGGCAAGCACGTGTGGTGCGAAAAGCCGATGGCGATGCATGCCGGTGAATGCGAGGCGATGATTGCTGCCTGC
AAACGCAACAAGGTGGCGCTGACGATCGGCTACCGCATGCAGCATGAGCCAAACACGCGGCGCGTGATTGCGATGGCCAG
CGAAAAACCGTTCGGTGCGATGCAACGCGTGCGTGCCGAGGCCGGGTACAACGGTTATCAAGGCACTGCCAAGGCCGACC
GCCCATGGCGGTTGCGTTCGCAGTTCGGTGGTGGCGCGATGTACGACATGGGCGTGTATCCGCTCAATGCCGCGCGCTAC
ACCGTGGGTGCCGAGCCGCTGGCGGTGACCGCCAAACGCTGGACCGACCGACCCGATCTGTTCGATGAAGTCGACGAACA
CATGGACTTCACCCTGGAGTTTCCCAATGCGGTCCGGGCCGAGTGCAAGACCAGCTTCGGCAAGAACATGAATGTGCTGC
GTGCCGAATGCGAGCGCGGTTGGTACGAATTGTCGCCGTTCCAGAGCTATCAGGGCGTGACCGGCAAGGCCAGCGATGGA
CGCGTGTTCGACGCCAAGGTGCCGCATCAGCAGGCGCTGCAGATGGACGAAGACGCGCTGGCGATCATGAACGGCACACC
ATTACGTGCGCCGGGCGAAGAAGGCCTGCGCGACATCCGCATCGTCGATGCGATCTATCGCTCGGCGCGCGAGGGCAGCA
AGCGCATCGTGCTGTAA

Upstream 100 bases:

>100_bases
GTCATGCGCAATGCTCCTGAGTGATCGCCAGCAGTGTGCCAGAACGTGCAGCGCCACCATGGCGGTGATCACACCCGATC
AAGTAAGGTGCGCGAGCAGT

Downstream 100 bases:

>100_bases
GGGTGGCCGGCTCCGCCGATGGGCGGAGTGCGGGCGCTGCATGCGCTGAGCAGTGGGCTGGCTCAGCGTAGGCTGCACGA
TGCAGTGCGGACGCGTTGTA

Product: glucose-fructose oxidoreductase

Products: NA

Alternate protein names: GFOR [H]

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MPTLAKEVCMSVESITRRRLLAAFGGAGILLAAPTWAVPKKKPGKPLNVALVGLGSYASEQLAPGLALTKHCKLAGIVTG
TPSKIPQWQSKYGIADRNVYSYENFDRIADNDDIDVVYIVTPTHLHAPLTLRAAAAGKHVWCEKPMAMHAGECEAMIAAC
KRNKVALTIGYRMQHEPNTRRVIAMASEKPFGAMQRVRAEAGYNGYQGTAKADRPWRLRSQFGGGAMYDMGVYPLNAARY
TVGAEPLAVTAKRWTDRPDLFDEVDEHMDFTLEFPNAVRAECKTSFGKNMNVLRAECERGWYELSPFQSYQGVTGKASDG
RVFDAKVPHQQALQMDEDALAIMNGTPLRAPGEEGLRDIRIVDAIYRSAREGSKRIVL

Sequences:

>Translated_378_residues
MPTLAKEVCMSVESITRRRLLAAFGGAGILLAAPTWAVPKKKPGKPLNVALVGLGSYASEQLAPGLALTKHCKLAGIVTG
TPSKIPQWQSKYGIADRNVYSYENFDRIADNDDIDVVYIVTPTHLHAPLTLRAAAAGKHVWCEKPMAMHAGECEAMIAAC
KRNKVALTIGYRMQHEPNTRRVIAMASEKPFGAMQRVRAEAGYNGYQGTAKADRPWRLRSQFGGGAMYDMGVYPLNAARY
TVGAEPLAVTAKRWTDRPDLFDEVDEHMDFTLEFPNAVRAECKTSFGKNMNVLRAECERGWYELSPFQSYQGVTGKASDG
RVFDAKVPHQQALQMDEDALAIMNGTPLRAPGEEGLRDIRIVDAIYRSAREGSKRIVL
>Mature_377_residues
PTLAKEVCMSVESITRRRLLAAFGGAGILLAAPTWAVPKKKPGKPLNVALVGLGSYASEQLAPGLALTKHCKLAGIVTGT
PSKIPQWQSKYGIADRNVYSYENFDRIADNDDIDVVYIVTPTHLHAPLTLRAAAAGKHVWCEKPMAMHAGECEAMIAACK
RNKVALTIGYRMQHEPNTRRVIAMASEKPFGAMQRVRAEAGYNGYQGTAKADRPWRLRSQFGGGAMYDMGVYPLNAARYT
VGAEPLAVTAKRWTDRPDLFDEVDEHMDFTLEFPNAVRAECKTSFGKNMNVLRAECERGWYELSPFQSYQGVTGKASDGR
VFDAKVPHQQALQMDEDALAIMNGTPLRAPGEEGLRDIRIVDAIYRSAREGSKRIVL

Specific function: Unknown

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=177, Percent_Identity=26.5536723163842, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24581117, Length=185, Percent_Identity=28.1081081081081, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008354
- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104
- InterPro:   IPR006311 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.99.28 [H]

Molecular weight: Translated: 41619; Mature: 41488

Theoretical pI: Translated: 9.10; Mature: 9.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTLAKEVCMSVESITRRRLLAAFGGAGILLAAPTWAVPKKKPGKPLNVALVGLGSYASE
CCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCHHHH
QLAPGLALTKHCKLAGIVTGTPSKIPQWQSKYGIADRNVYSYENFDRIADNDDIDVVYIV
HHCCCCHHHHCCEEEEEEECCCCCCCCHHHHCCCCCCCEECCCCHHHHCCCCCCEEEEEE
TPTHLHAPLTLRAAAAGKHVWCEKPMAMHAGECEAMIAACKRNKVALTIGYRMQHEPNTR
CCCCCCCCEEEEECCCCCCEEECCCHHHCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCC
RVIAMASEKPFGAMQRVRAEAGYNGYQGTAKADRPWRLRSQFGGGAMYDMGVYPLNAARY
EEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHCCCCEEEECCCEEECCCEE
TVGAEPLAVTAKRWTDRPDLFDEVDEHMDFTLEFPNAVRAECKTSFGKNMNVLRAECERG
EECCCCEEEEHHHCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHCC
WYELSPFQSYQGVTGKASDGRVFDAKVPHQQALQMDEDALAIMNGTPLRAPGEEGLRDIR
CEECCCCHHCCCCCCCCCCCEEEECCCCHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHH
IVDAIYRSAREGSKRIVL
HHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
PTLAKEVCMSVESITRRRLLAAFGGAGILLAAPTWAVPKKKPGKPLNVALVGLGSYASE
CCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCHHHH
QLAPGLALTKHCKLAGIVTGTPSKIPQWQSKYGIADRNVYSYENFDRIADNDDIDVVYIV
HHCCCCHHHHCCEEEEEEECCCCCCCCHHHHCCCCCCCEECCCCHHHHCCCCCCEEEEEE
TPTHLHAPLTLRAAAAGKHVWCEKPMAMHAGECEAMIAACKRNKVALTIGYRMQHEPNTR
CCCCCCCCEEEEECCCCCCEEECCCHHHCCCHHHHHHHHHCCCCEEEEEEEEECCCCCCC
RVIAMASEKPFGAMQRVRAEAGYNGYQGTAKADRPWRLRSQFGGGAMYDMGVYPLNAARY
EEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHCCCCEEEECCCEEECCCEE
TVGAEPLAVTAKRWTDRPDLFDEVDEHMDFTLEFPNAVRAECKTSFGKNMNVLRAECERG
EECCCCEEEEHHHCCCCCHHHHHHHHHCCEEEECCHHHHHHHHHHCCCCCHHHHHHHHCC
WYELSPFQSYQGVTGKASDGRVFDAKVPHQQALQMDEDALAIMNGTPLRAPGEEGLRDIR
CEECCCCHHCCCCCCCCCCCEEEECCCCHHHHHCCCCCCEEEECCCCCCCCCHHHHHHHH
IVDAIYRSAREGSKRIVL
HHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1537789; 8472911; 8994968 [H]