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The map label for this gene is ubiH [H]

Identifier: 21241642

GI number: 21241642

Start: 1033686

End: 1034894

Strand: Direct

Name: ubiH [H]

Synonym: XAC0872

Alternate gene names: 21241642

Gene position: 1033686-1034894 (Clockwise)

Preceding gene: 21241630

Following gene: 21241643

Centisome position: 19.97

GC content: 69.89

Gene sequence:

>1209_bases
ATGACACATCCCCATGACGTTCTGATCGTTGGCGGCGGCCTGGTCGGCTCCAGCCTCGCGATTGCGCTGGACCGCCTCGG
CCTGGATGTCGGGCTGGTGGAGGCCACTCCGGCCGGTGCGCCGCCGGCAGTGTTTGATCAACGCAACCTCAGTTTCGCCG
CGGCCACCGTGAACGCGCTGGGTGCGCTCGGGGTGATGGCCAAGCTGCGCAGCCCGCCCGGGCCGATCCGGCGCATCCAT
GTCAGCCGCGCCGGGGACTTCGGCCGCGTGCAACTGGACGCGGCCGATTATGGCCGCGACGCCTTCGGCCAGGTGGTGGT
GGCACGCGACTTCGGCGATGCCTTGCAAACGCGTCTGGACGAACTGACCCATCTGCGCCGTTACCGGCCTGCGCGGTGCA
TCGGCATAGAGCCGGTGCAGGACGATCTGCGCGCGGTGCGCCTGGCCACCGATGCGGGCGAGCAACGTGTGCAGGCCAAA
CTGGTGGTCGGCGCCGACGGCAGCCATAGCGCGGTGCGCGAGCTGCTGCATATCGGTACCGATGCCCACGATTTCCTGCA
GACCCTGTTCGTGGCGCGCGTGCGTGCGTCACGACCGCCCGATGGCACGGCCTGGGAGCGTTTTGGCGAGCATGGGCCAA
CCGCGCTGTTGCCGCGCGGCGACCGCCATTACGGCGCGATCCATTGCGTGGCGCGCGCCGAGTCCGAAGCCGTGGCTGCG
CTCGACGACGCCGGCTGGCTGGCCCGCCTGCAGCGAGCAGCCGGCTGGCGTGCCGGGCGCTTGGTCGCCAGCGGCGAGCG
CAGTGCCTATCCGCTGGTGCAGGTGCTGGCCAACAGCCTCATCGCCGAACGCGTGGTGCTGCTGGGCAATGCGGCGCAGA
CGCTGCATCCGATCGGCGCACAGGGTTTCAACCTGGGGTTGCGCGATGCGCTGACGCTGGCCGAATTGATCGAGCACGAT
CGCAGCGATGCCGGTGCCGGTGCGTTGCTGGCCGAGTATCTGGCGCGGCGGCGGGTGGACCGCGAGCACACCATCGGGTT
TTCCAGCGGTCTGGCGCGGCTCACCGGCAACCCGGCGCCGTTGCTGCGGCCGTTGCGTAGCCTGGGCTTGTTTGCGACCT
CGCAGGCGGCCCCGCTGCAATCGATGCTGGTGGGCGGTGCCATGGGCTTCCGTGGCGATGTGCCGCAACTGTGCCGGAGC
AGCGCATGA

Upstream 100 bases:

>100_bases
AGTGCGCGCAAGCCATGCAAGGTGCAGGCGGCAGCGGGCGCGGCAAGATGTCCCGCCCTCCGGCGGCAACGCGCAGGGGG
CGAAGGCTTATCATGTGGGA

Downstream 100 bases:

>100_bases
GCCGGCGCAGCACGCGCGAGGCCGTGATCGTCGGCGGCGGCGTTGTCGGCGCGGCCTGCGCGCTGGCGTTGAACGATGCC
GGGCTGAGCGTTGCCCTGGT

Product: 2-octaprenyl-6-methoxyphenyl hydroxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MTHPHDVLIVGGGLVGSSLAIALDRLGLDVGLVEATPAGAPPAVFDQRNLSFAAATVNALGALGVMAKLRSPPGPIRRIH
VSRAGDFGRVQLDAADYGRDAFGQVVVARDFGDALQTRLDELTHLRRYRPARCIGIEPVQDDLRAVRLATDAGEQRVQAK
LVVGADGSHSAVRELLHIGTDAHDFLQTLFVARVRASRPPDGTAWERFGEHGPTALLPRGDRHYGAIHCVARAESEAVAA
LDDAGWLARLQRAAGWRAGRLVASGERSAYPLVQVLANSLIAERVVLLGNAAQTLHPIGAQGFNLGLRDALTLAELIEHD
RSDAGAGALLAEYLARRRVDREHTIGFSSGLARLTGNPAPLLRPLRSLGLFATSQAAPLQSMLVGGAMGFRGDVPQLCRS
SA

Sequences:

>Translated_402_residues
MTHPHDVLIVGGGLVGSSLAIALDRLGLDVGLVEATPAGAPPAVFDQRNLSFAAATVNALGALGVMAKLRSPPGPIRRIH
VSRAGDFGRVQLDAADYGRDAFGQVVVARDFGDALQTRLDELTHLRRYRPARCIGIEPVQDDLRAVRLATDAGEQRVQAK
LVVGADGSHSAVRELLHIGTDAHDFLQTLFVARVRASRPPDGTAWERFGEHGPTALLPRGDRHYGAIHCVARAESEAVAA
LDDAGWLARLQRAAGWRAGRLVASGERSAYPLVQVLANSLIAERVVLLGNAAQTLHPIGAQGFNLGLRDALTLAELIEHD
RSDAGAGALLAEYLARRRVDREHTIGFSSGLARLTGNPAPLLRPLRSLGLFATSQAAPLQSMLVGGAMGFRGDVPQLCRS
SA
>Mature_401_residues
THPHDVLIVGGGLVGSSLAIALDRLGLDVGLVEATPAGAPPAVFDQRNLSFAAATVNALGALGVMAKLRSPPGPIRRIHV
SRAGDFGRVQLDAADYGRDAFGQVVVARDFGDALQTRLDELTHLRRYRPARCIGIEPVQDDLRAVRLATDAGEQRVQAKL
VVGADGSHSAVRELLHIGTDAHDFLQTLFVARVRASRPPDGTAWERFGEHGPTALLPRGDRHYGAIHCVARAESEAVAAL
DDAGWLARLQRAAGWRAGRLVASGERSAYPLVQVLANSLIAERVVLLGNAAQTLHPIGAQGFNLGLRDALTLAELIEHDR
SDAGAGALLAEYLARRRVDREHTIGFSSGLARLTGNPAPLLRPLRSLGLFATSQAAPLQSMLVGGAMGFRGDVPQLCRSS
A

Specific function: Oxygenase that introduces the hydroxyl group at carbon four of 2-octaprenyl-6-methoxyphenol resulting in the formation of 2-octaprenyl-6-methoxy-1,4-benzoquinone [H]

COG id: COG0654

COG function: function code HC; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiH/COQ6 family [H]

Homologues:

Organism=Homo sapiens, GI32967305, Length=378, Percent_Identity=26.7195767195767, Blast_Score=85, Evalue=9e-17,
Organism=Homo sapiens, GI32967307, Length=267, Percent_Identity=28.8389513108614, Blast_Score=83, Evalue=5e-16,
Organism=Escherichia coli, GI1789274, Length=392, Percent_Identity=36.4795918367347, Blast_Score=211, Evalue=7e-56,
Organism=Escherichia coli, GI1786883, Length=404, Percent_Identity=29.9504950495049, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789273, Length=409, Percent_Identity=28.1173594132029, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002938
- InterPro:   IPR003042
- InterPro:   IPR018168
- InterPro:   IPR010971
- InterPro:   IPR011295 [H]

Pfam domain/function: PF01494 FAD_binding_3 [H]

EC number: 1.14.13.-

Molecular weight: Translated: 42617; Mature: 42486

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPHDVLIVGGGLVGSSLAIALDRLGLDVGLVEATPAGAPPAVFDQRNLSFAAATVNAL
CCCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
GALGVMAKLRSPPGPIRRIHVSRAGDFGRVQLDAADYGRDAFGQVVVARDFGDALQTRLD
HHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECHHHCCCCCCCCEEEEEHHHHHHHHHHH
ELTHLRRYRPARCIGIEPVQDDLRAVRLATDAGEQRVQAKLVVGADGSHSAVRELLHIGT
HHHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCCHHEEEEEEEECCCCHHHHHHHHHCCC
DAHDFLQTLFVARVRASRPPDGTAWERFGEHGPTALLPRGDRHYGAIHCVARAESEAVAA
CHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCCHHHH
LDDAGWLARLQRAAGWRAGRLVASGERSAYPLVQVLANSLIAERVVLLGNAAQTLHPIGA
HCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
QGFNLGLRDALTLAELIEHDRSDAGAGALLAEYLARRRVDREHTIGFSSGLARLTGNPAP
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHCCCHHCCHHHHCCCCHH
LLRPLRSLGLFATSQAAPLQSMLVGGAMGFRGDVPQLCRSSA
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCC
>Mature Secondary Structure 
THPHDVLIVGGGLVGSSLAIALDRLGLDVGLVEATPAGAPPAVFDQRNLSFAAATVNAL
CCCCEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
GALGVMAKLRSPPGPIRRIHVSRAGDFGRVQLDAADYGRDAFGQVVVARDFGDALQTRLD
HHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECHHHCCCCCCCCEEEEEHHHHHHHHHHH
ELTHLRRYRPARCIGIEPVQDDLRAVRLATDAGEQRVQAKLVVGADGSHSAVRELLHIGT
HHHHHHHCCCCCEECCCCHHHHHHHHHHHHCCCCHHEEEEEEEECCCCHHHHHHHHHCCC
DAHDFLQTLFVARVRASRPPDGTAWERFGEHGPTALLPRGDRHYGAIHCVARAESEAVAA
CHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEECCCCCCCCCEEEEEECCCCCHHHH
LDDAGWLARLQRAAGWRAGRLVASGERSAYPLVQVLANSLIAERVVLLGNAAQTLHPIGA
HCCHHHHHHHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCC
QGFNLGLRDALTLAELIEHDRSDAGAGALLAEYLARRRVDREHTIGFSSGLARLTGNPAP
CCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHCCCHHCCHHHHCCCCHH
LLRPLRSLGLFATSQAAPLQSMLVGGAMGFRGDVPQLCRSSA
HHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1339425; 9278503 [H]