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The map label for this gene is yeiM [C]

Identifier: 21241589

GI number: 21241589

Start: 978978

End: 980276

Strand: Reverse

Name: yeiM [C]

Synonym: XAC0819

Alternate gene names: 21241589

Gene position: 980276-978978 (Counterclockwise)

Preceding gene: 21241590

Following gene: 21241588

Centisome position: 18.94

GC content: 64.28

Gene sequence:

>1299_bases
ATGGTCGAAGGTTTGGGAAGGATCGGTTTCGGCCTGTTCGGTCTGGCGGTGCTCATCGGCATCACCTGGCTGTTTTCGAG
CAACCGCCGCGCGATCGACTGGAAGCTGGTCGCCACCGGTCTGGCCCTGCAGATCTCGTTCGCCGCACTGGTGTTGCTGG
TGCCGGGCGGGCGCGACGTCTTCGACGCGCTGGGCAAGGGCTTTGTCAAGGTGCTGAGTTTCGTCAATGAAGGGTCCACC
TTCATCTTCGGCAACCTGATGAACATCGACAGCTACGGCTTCATCTTTGCGTTCCAGGTGCTGCCCACCATCATCTTCTT
CTCGGCGCTGATGGGCGTGCTTTACCACCTGGGCGTGATGCAGATGGTGGTGCGTGCGATGGCCTGGGCGATCACCAAGG
TGATGCGCGTTTCCGGTGCGGAAACCACCAGCGTGTGCGCCAGCGTCTTCATCGGCCAGACCGAAGCGCCGCTGACGGTG
CGCCCGTACATCCCCAAGATGACCCAGTCCGAGCTGCTGACGATGATGATCGGCGGCATGGCGCATATCGCCGGTGGCGT
GCTGGCTGCATACGTCGGCATGCTCGGCGGCAGCGATCCGGCGCAACAGGCGTTTTATGCCAAGCATCTGTTGGCCGCCA
GCATCATGGCCGCGCCCGCCACGCTGGTGGTCGCCAAGCTGCTGGTGCCGGAAACCGGCACCCCGCTGACCCGCGGCACG
GTCAAGATGGAAGTGGAAAAAACCACCAGCAATGTCATCGATGCGGCTGCGGCCGGTGCCGGCGACGGCTTGCGCCTGGC
ACTGAACATCGGCGCGATGCTGCTGGCCTTCATCGCGCTGATTGCGCTGATCAACGCACCGCTGACCTGGCTGGGCGAGG
TCACCGGCGCCACCGCGCTGCTGGGCCGCCCGACCAACCTGTCGACGATCTTCGGCTACGTGCTGGCGCCGATCGCCTGG
GTGATCGGCACCCCGTGGGTGGATGCGACAACGGTCGGTTCGTTGATCGGCCAGAAGGTGGTGATCAACGAGTTCGTCGC
CTACAGCGAGTTGTCGCGCATCGTCAAGGGCGAAGTGCGGGGCGTGGGCCTGAGCGCAGAAGGCCGCTTGATCGCCACCT
ACGCGCTGTGCGGCTTCGCCAATTTCAGCTCGATCGCGATCCAGATCGGCGGGATCGGCGGGCTGGCGCCGGAACGTCGT
CACGATCTGGCCAACTTCGGCCTGCGTGCGGTGCTCGGCGGTTCGATCGCCACCTTCATGACCGCTACCATTGCCGGCGT
GCTGTCGCATTTCGGTTGA

Upstream 100 bases:

>100_bases
TCTGTGGGCCAACCGGGAGCATCTGAATGCCGCTCGCCTTGCCCCCTGTCACCCCCTGCTCTAGGCTTCCCGTTTTGCCG
TCAGCAGCCCGGGGATTGGA

Downstream 100 bases:

>100_bases
GGTGGTGCGGGTTCATCGGCGTGACGGTCTAATCACTGCACGCCGCGTTTCATCCAGTCTTTCAAGTCAGTCATTCAAGG
CAAGGTATTTATGAGTTCGG

Product: nucleoside transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 432

Protein sequence:

>432_residues
MVEGLGRIGFGLFGLAVLIGITWLFSSNRRAIDWKLVATGLALQISFAALVLLVPGGRDVFDALGKGFVKVLSFVNEGST
FIFGNLMNIDSYGFIFAFQVLPTIIFFSALMGVLYHLGVMQMVVRAMAWAITKVMRVSGAETTSVCASVFIGQTEAPLTV
RPYIPKMTQSELLTMMIGGMAHIAGGVLAAYVGMLGGSDPAQQAFYAKHLLAASIMAAPATLVVAKLLVPETGTPLTRGT
VKMEVEKTTSNVIDAAAAGAGDGLRLALNIGAMLLAFIALIALINAPLTWLGEVTGATALLGRPTNLSTIFGYVLAPIAW
VIGTPWVDATTVGSLIGQKVVINEFVAYSELSRIVKGEVRGVGLSAEGRLIATYALCGFANFSSIAIQIGGIGGLAPERR
HDLANFGLRAVLGGSIATFMTATIAGVLSHFG

Sequences:

>Translated_432_residues
MVEGLGRIGFGLFGLAVLIGITWLFSSNRRAIDWKLVATGLALQISFAALVLLVPGGRDVFDALGKGFVKVLSFVNEGST
FIFGNLMNIDSYGFIFAFQVLPTIIFFSALMGVLYHLGVMQMVVRAMAWAITKVMRVSGAETTSVCASVFIGQTEAPLTV
RPYIPKMTQSELLTMMIGGMAHIAGGVLAAYVGMLGGSDPAQQAFYAKHLLAASIMAAPATLVVAKLLVPETGTPLTRGT
VKMEVEKTTSNVIDAAAAGAGDGLRLALNIGAMLLAFIALIALINAPLTWLGEVTGATALLGRPTNLSTIFGYVLAPIAW
VIGTPWVDATTVGSLIGQKVVINEFVAYSELSRIVKGEVRGVGLSAEGRLIATYALCGFANFSSIAIQIGGIGGLAPERR
HDLANFGLRAVLGGSIATFMTATIAGVLSHFG
>Mature_432_residues
MVEGLGRIGFGLFGLAVLIGITWLFSSNRRAIDWKLVATGLALQISFAALVLLVPGGRDVFDALGKGFVKVLSFVNEGST
FIFGNLMNIDSYGFIFAFQVLPTIIFFSALMGVLYHLGVMQMVVRAMAWAITKVMRVSGAETTSVCASVFIGQTEAPLTV
RPYIPKMTQSELLTMMIGGMAHIAGGVLAAYVGMLGGSDPAQQAFYAKHLLAASIMAAPATLVVAKLLVPETGTPLTRGT
VKMEVEKTTSNVIDAAAAGAGDGLRLALNIGAMLLAFIALIALINAPLTWLGEVTGATALLGRPTNLSTIFGYVLAPIAW
VIGTPWVDATTVGSLIGQKVVINEFVAYSELSRIVKGEVRGVGLSAEGRLIATYALCGFANFSSIAIQIGGIGGLAPERR
HDLANFGLRAVLGGSIATFMTATIAGVLSHFG

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI42542381, Length=425, Percent_Identity=37.6470588235294, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI227116277, Length=427, Percent_Identity=37.4707259953162, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI11545853, Length=432, Percent_Identity=38.6574074074074, Blast_Score=271, Evalue=1e-72,
Organism=Escherichia coli, GI1788485, Length=421, Percent_Identity=37.5296912114014, Blast_Score=267, Evalue=8e-73,
Organism=Escherichia coli, GI1788488, Length=420, Percent_Identity=38.5714285714286, Blast_Score=261, Evalue=9e-71,
Organism=Escherichia coli, GI1788737, Length=424, Percent_Identity=30.4245283018868, Blast_Score=177, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17560276, Length=410, Percent_Identity=34.390243902439, Blast_Score=225, Evalue=3e-59,
Organism=Caenorhabditis elegans, GI71991794, Length=432, Percent_Identity=32.4074074074074, Blast_Score=219, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI25146537, Length=229, Percent_Identity=31.8777292576419, Blast_Score=121, Evalue=6e-28,
Organism=Drosophila melanogaster, GI45552517, Length=407, Percent_Identity=36.3636363636364, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI19921868, Length=407, Percent_Identity=36.3636363636364, Blast_Score=271, Evalue=8e-73,
Organism=Drosophila melanogaster, GI45552519, Length=407, Percent_Identity=36.3636363636364, Blast_Score=271, Evalue=9e-73,
Organism=Drosophila melanogaster, GI281360430, Length=425, Percent_Identity=35.2941176470588, Blast_Score=229, Evalue=2e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 45165; Mature: 45165

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEGLGRIGFGLFGLAVLIGITWLFSSNRRAIDWKLVATGLALQISFAALVLLVPGGRDV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHEEECCCCHHH
FDALGKGFVKVLSFVNEGSTFIFGNLMNIDSYGFIFAFQVLPTIIFFSALMGVLYHLGVM
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMVVRAMAWAITKVMRVSGAETTSVCASVFIGQTEAPLTVRPYIPKMTQSELLTMMIGGM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHH
AHIAGGVLAAYVGMLGGSDPAQQAFYAKHLLAASIMAAPATLVVAKLLVPETGTPLTRGT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
VKMEVEKTTSNVIDAAAAGAGDGLRLALNIGAMLLAFIALIALINAPLTWLGEVTGATAL
EEEEEEHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHH
LGRPTNLSTIFGYVLAPIAWVIGTPWVDATTVGSLIGQKVVINEFVAYSELSRIVKGEVR
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GVGLSAEGRLIATYALCGFANFSSIAIQIGGIGGLAPERRHDLANFGLRAVLGGSIATFM
EECCCCCCCEEEHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
TATIAGVLSHFG
HHHHHHHHHHCC
>Mature Secondary Structure
MVEGLGRIGFGLFGLAVLIGITWLFSSNRRAIDWKLVATGLALQISFAALVLLVPGGRDV
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEHHHHHHHHHHHHHEEECCCCHHH
FDALGKGFVKVLSFVNEGSTFIFGNLMNIDSYGFIFAFQVLPTIIFFSALMGVLYHLGVM
HHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QMVVRAMAWAITKVMRVSGAETTSVCASVFIGQTEAPLTVRPYIPKMTQSELLTMMIGGM
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHHHHH
AHIAGGVLAAYVGMLGGSDPAQQAFYAKHLLAASIMAAPATLVVAKLLVPETGTPLTRGT
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCE
VKMEVEKTTSNVIDAAAAGAGDGLRLALNIGAMLLAFIALIALINAPLTWLGEVTGATAL
EEEEEEHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHH
LGRPTNLSTIFGYVLAPIAWVIGTPWVDATTVGSLIGQKVVINEFVAYSELSRIVKGEVR
CCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHC
GVGLSAEGRLIATYALCGFANFSSIAIQIGGIGGLAPERRHDLANFGLRAVLGGSIATFM
EECCCCCCCEEEHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCHHHHHH
TATIAGVLSHFG
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]