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The map label for this gene is rbsK [H]

Identifier: 21241588

GI number: 21241588

Start: 977937

End: 978887

Strand: Reverse

Name: rbsK [H]

Synonym: XAC0818

Alternate gene names: 21241588

Gene position: 978887-977937 (Counterclockwise)

Preceding gene: 21241589

Following gene: 21241587

Centisome position: 18.91

GC content: 68.45

Gene sequence:

>951_bases
ATGAGTTCGGTCGTCGTTGTCGGGTCCTTCAATGTCGATCACGTGTGGCGCTGCGATGCCTTGCCGGTGCCGGGTGCGAC
CATCGCCGGGCGCTACAGCACCGGCCCGGGCGGCAAGGGCTTCAATCAGGCGGTTGCGGCCGCACGTGCTGGCGCCAGGA
CGCATTTCTTGTGCGCGCTGGGCGACGATGCCGGTGGTGCGTTGGCGCGCTCGCTGGCCGCGCACGATGGCTTTGCGCTG
ATCGCCGAGCCCAGCAATGAACCGACCGGCACTGGCGGCATCTACGTCGACGGGCATGGCCGCAACACCATCGTGATCGG
CGCCGGCGCCAACGCCGTGTTGAGCCCGGCCTTCATCGAGAACCAGCGCCCGCTGGTGGCTGCAGCAAAAGTGCTGCTGG
CGCAGCTGGAATCTCCGGCCGAGACGGTCGAGTCTGCACTGGCGCTGGCGCACGAATGCGGCGTGCTGACGGTACTCAAT
GCCGCCCCGGCCAATGCGCCGACATCGATCGGCCTGCTCAAGCTCTCGGATGTGCTGACGCCCAACGAAACCGAATTCGC
CGCGCTGCTCGGTCGCCATGTCGGCGAGCGCATCAATGCCGACGACGTCGCCGCGCTGGACGGCAATACGCTGCATTCGC
TGTGCCGCAAGCTGCTGCCGGGCGGTACCGTGGTGGTGACGCTGGGCGCGGTGGGCGCCTTCATTTCGCACGCCGAAGAA
CAACTGCGCGGCGATACCCAGGCGCATTACCGGGTGGGCGCGGAAAGCGCGCAGACCATCGACACCACCGGTGCCGGCGA
CGCCTTCAACGGTGCGCTGGTTGCCTCGCTGGCGCAGCTGCCGGCTGCCAGCTTCGCAACCCACGTGCGCTTCGCCACCC
GTTACGCGGCGCGCTCCACCGAGGTGGAAGGTGCGGCGGTGTCGATGCCGCGGCTGCGCGCGGACGACTGA

Upstream 100 bases:

>100_bases
TTTCGGTTGAGGTGGTGCGGGTTCATCGGCGTGACGGTCTAATCACTGCACGCCGCGTTTCATCCAGTCTTTCAAGTCAG
TCATTCAAGGCAAGGTATTT

Downstream 100 bases:

>100_bases
GACCGCGGTTCACTGCGATCGGCGTGCGCCACACGCGCATGCCCTGGATGCCGCACCCTGATTGGCGTGCCCAGGTTTTT
GCAGGAATGCGCGCGCATGT

Product: ribokinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGARTHFLCALGDDAGGALARSLAAHDGFAL
IAEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIENQRPLVAAAKVLLAQLESPAETVESALALAHECGVLTVLN
AAPANAPTSIGLLKLSDVLTPNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEE
QLRGDTQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQLPAASFATHVRFATRYAARSTEVEGAAVSMPRLRADD

Sequences:

>Translated_316_residues
MSSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGARTHFLCALGDDAGGALARSLAAHDGFAL
IAEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIENQRPLVAAAKVLLAQLESPAETVESALALAHECGVLTVLN
AAPANAPTSIGLLKLSDVLTPNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEE
QLRGDTQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQLPAASFATHVRFATRYAARSTEVEGAAVSMPRLRADD
>Mature_315_residues
SSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGARTHFLCALGDDAGGALARSLAAHDGFALI
AEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIENQRPLVAAAKVLLAQLESPAETVESALALAHECGVLTVLNA
APANAPTSIGLLKLSDVLTPNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEEQ
LRGDTQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQLPAASFATHVRFATRYAARSTEVEGAAVSMPRLRADD

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=311, Percent_Identity=35.3697749196142, Blast_Score=134, Evalue=9e-32,
Organism=Escherichia coli, GI1790193, Length=281, Percent_Identity=41.9928825622776, Blast_Score=176, Evalue=2e-45,
Organism=Caenorhabditis elegans, GI17532905, Length=317, Percent_Identity=30.2839116719243, Blast_Score=100, Evalue=1e-21,
Organism=Saccharomyces cerevisiae, GI6319884, Length=337, Percent_Identity=27.893175074184, Blast_Score=79, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20128807, Length=317, Percent_Identity=35.6466876971609, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24583886, Length=311, Percent_Identity=30.8681672025724, Blast_Score=98, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 32113; Mature: 31982

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00584 PFKB_KINASES_2 ; PS00107 PROTEIN_KINASE_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGARTHFLCAL
CCCEEEEECCCCCCEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
GDDAGGALARSLAAHDGFALIAEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIE
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEECCCCHHCCCHHHC
NQRPLVAAAKVLLAQLESPAETVESALALAHECGVLTVLNAAPANAPTSIGLLKLSDVLT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEHHCCC
PNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEE
CCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHH
QLRGDTQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQLPAASFATHVRFATRYAARST
HHCCCCHHHEEECCCCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
EVEGAAVSMPRLRADD
CCCCCEECCCCCCCCC
>Mature Secondary Structure 
SSVVVVGSFNVDHVWRCDALPVPGATIAGRYSTGPGGKGFNQAVAAARAGARTHFLCAL
CCEEEEECCCCCCEEEECCCCCCCCEEECCCCCCCCCCCHHHHHHHHHCCCCEEEEEEE
GDDAGGALARSLAAHDGFALIAEPSNEPTGTGGIYVDGHGRNTIVIGAGANAVLSPAFIE
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCEEEECCCCEEEEEECCCCHHCCCHHHC
NQRPLVAAAKVLLAQLESPAETVESALALAHECGVLTVLNAAPANAPTSIGLLKLSDVLT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCEEEEEEHHCCC
PNETEFAALLGRHVGERINADDVAALDGNTLHSLCRKLLPGGTVVVTLGAVGAFISHAEE
CCCHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHH
QLRGDTQAHYRVGAESAQTIDTTGAGDAFNGALVASLAQLPAASFATHVRFATRYAARST
HHCCCCHHHEEECCCCCCEEECCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
EVEGAAVSMPRLRADD
CCCCCEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]