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The map label for this gene is ribA [H]

Identifier: 21241520

GI number: 21241520

Start: 889044

End: 890183

Strand: Direct

Name: ribA [H]

Synonym: XAC0749

Alternate gene names: 21241520

Gene position: 889044-890183 (Clockwise)

Preceding gene: 21241519

Following gene: 21241521

Centisome position: 17.18

GC content: 67.37

Gene sequence:

>1140_bases
ATGAATTTCGCGCCCGTTCCGGAACTGATCGAAGAACTGCGCGCCGGACGCATGGTGGTCATCGTCGATGACGAAGACCG
CGAAAACGAAGGCGATCTGATCATGGCCGCCGAGTTGGTGAAGCCGTCGGACATCAACTTCATGGTCACCCACGCGCGCG
GGCTGGTGTGCCTGTCGCTGACCCGCGAGCGCTGCGCGCAGCTGGGTCTGGCGCCGATGGTGCGCAACAACACCGCGCAG
TTCCAGACCAACTTCACTGTCAGCATCGAAGCGGCCGAAGGGGTGACCACCGGCATTTCGGCCTACGACCGCGCGCACAC
CGTGCGCACCGCAGTCCGCCCGGATGCCCGGCCACAGGATTTGAGCCAGCCCGGGCATATCTTCCCGTTGATCTCCCAGC
CCGGTGGCGTGCTGACCCGTGCCGGCCACACCGAAGCGGCCAGCGATCTGCCGATGCTGGCCGGACTGGAACCGGCCGGT
GTGCTGGTGGAAGTGCTCAACCCGGACGGCAGCATGGCGCGTCGCCCGCAGCTGGAAGTGTTCGCGCGCGAGCATGGGCT
GAAGATGGGCTCGATCGCCGACCTGATCGCATATCGGCTTGCCAATGAGCACACCGTCGAGCGCGTGGACGAGCGCGAGA
TCACCACCGAATTCGGTCCGTTCAAGCTGGTGACCTACCGCGACCGCATCGCGCACGACCTGCACTTTGCGCTGTTGCGC
GGGCGCGCCGATCCGCAGACGCCGACGCTGGTGCGCGTACAGGTGGAAAACCCATTGGCCGACCTGCTGCACTGGCAGCG
CGATGACTTCGGCGTGGCAGCCACTGATGCCTTGCGCGCGATCGCCGCCGAGGGGCAGGGCGTGATGGTGGTGCTGTCGG
CGCCACGCGACAGCGAATCGCTGCTGGCACGGCTGCGCCAGCAGCCCGAAGCCGCCGCCAATGCCAAGGACGTGAGTCAG
TGGCGGCGCAACGGCGCCGGTGCGCAGATCCTGGCCGACCTCGGCCTGGGCAAGTTGCGCGTGCTGGGCACCCCCCGGCG
CCAGGTGGGGTTGGCCGGATTCGGGCTGGAGGTGGTCGAGTATTTGGAGTGCCATGCCGGTGAAGGCGTGCGCTCGGTGC
CGCCGTCTGCCGTTCCCTGA

Upstream 100 bases:

>100_bases
ACACCGCGTTTGCGCAGACTGCGGTCGGTGCGGCGGTGAACCTGGAAATCGATCTGGTGGCGCGCTACGTCGAACGCCTG
CTCGGCACGCGGGGGGCAGC

Downstream 100 bases:

>100_bases
GATGGCTGCGAGCGGTTGCCGCAATCACTTGGCCGGTCGCGGTGGTCTCGACTGTTGCGTTGCTGACGGCGCGCAGCTGT
CAGCAACGCGGTGCGTGTGC

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase [H]

Number of amino acids: Translated: 379; Mature: 379

Protein sequence:

>379_residues
MNFAPVPELIEELRAGRMVVIVDDEDRENEGDLIMAAELVKPSDINFMVTHARGLVCLSLTRERCAQLGLAPMVRNNTAQ
FQTNFTVSIEAAEGVTTGISAYDRAHTVRTAVRPDARPQDLSQPGHIFPLISQPGGVLTRAGHTEAASDLPMLAGLEPAG
VLVEVLNPDGSMARRPQLEVFAREHGLKMGSIADLIAYRLANEHTVERVDEREITTEFGPFKLVTYRDRIAHDLHFALLR
GRADPQTPTLVRVQVENPLADLLHWQRDDFGVAATDALRAIAAEGQGVMVVLSAPRDSESLLARLRQQPEAAANAKDVSQ
WRRNGAGAQILADLGLGKLRVLGTPRRQVGLAGFGLEVVEYLECHAGEGVRSVPPSAVP

Sequences:

>Translated_379_residues
MNFAPVPELIEELRAGRMVVIVDDEDRENEGDLIMAAELVKPSDINFMVTHARGLVCLSLTRERCAQLGLAPMVRNNTAQ
FQTNFTVSIEAAEGVTTGISAYDRAHTVRTAVRPDARPQDLSQPGHIFPLISQPGGVLTRAGHTEAASDLPMLAGLEPAG
VLVEVLNPDGSMARRPQLEVFAREHGLKMGSIADLIAYRLANEHTVERVDEREITTEFGPFKLVTYRDRIAHDLHFALLR
GRADPQTPTLVRVQVENPLADLLHWQRDDFGVAATDALRAIAAEGQGVMVVLSAPRDSESLLARLRQQPEAAANAKDVSQ
WRRNGAGAQILADLGLGKLRVLGTPRRQVGLAGFGLEVVEYLECHAGEGVRSVPPSAVP
>Mature_379_residues
MNFAPVPELIEELRAGRMVVIVDDEDRENEGDLIMAAELVKPSDINFMVTHARGLVCLSLTRERCAQLGLAPMVRNNTAQ
FQTNFTVSIEAAEGVTTGISAYDRAHTVRTAVRPDARPQDLSQPGHIFPLISQPGGVLTRAGHTEAASDLPMLAGLEPAG
VLVEVLNPDGSMARRPQLEVFAREHGLKMGSIADLIAYRLANEHTVERVDEREITTEFGPFKLVTYRDRIAHDLHFALLR
GRADPQTPTLVRVQVENPLADLLHWQRDDFGVAATDALRAIAAEGQGVMVVLSAPRDSESLLARLRQQPEAAANAKDVSQ
WRRNGAGAQILADLGLGKLRVLGTPRRQVGLAGFGLEVVEYLECHAGEGVRSVPPSAVP

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate [H]

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the GTP cyclohydrolase II family [H]

Homologues:

Organism=Escherichia coli, GI1789420, Length=201, Percent_Identity=53.7313432835821, Blast_Score=218, Evalue=7e-58,
Organism=Saccharomyces cerevisiae, GI6320695, Length=205, Percent_Identity=40, Blast_Score=156, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR000422
- InterPro:   IPR000926
- InterPro:   IPR016299 [H]

Pfam domain/function: PF00926 DHBP_synthase; PF00925 GTP_cyclohydro2 [H]

EC number: =4.1.99.12 [H]

Molecular weight: Translated: 41176; Mature: 41176

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFAPVPELIEELRAGRMVVIVDDEDRENEGDLIMAAELVKPSDINFMVTHARGLVCLSL
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEEHH
TRERCAQLGLAPMVRNNTAQFQTNFTVSIEAAEGVTTGISAYDRAHTVRTAVRPDARPQD
HHHHHHHCCCCHHHCCCCEEEEEEEEEEEECCCCCHHCHHHHHHHHHHHHHCCCCCCCCC
LSQPGHIFPLISQPGGVLTRAGHTEAASDLPMLAGLEPAGVLVEVLNPDGSMARRPQLEV
CCCCCCEEEEECCCCCEEEECCCCCCCCCCCHHCCCCCCCEEEEEECCCCCCCCCCCHHH
FAREHGLKMGSIADLIAYRLANEHTVERVDEREITTEFGPFKLVTYRDRIAHDLHFALLR
HHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHH
GRADPQTPTLVRVQVENPLADLLHWQRDDFGVAATDALRAIAAEGQGVMVVLSAPRDSES
CCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHH
LLARLRQQPEAAANAKDVSQWRRNGAGAQILADLGLGKLRVLGTPRRQVGLAGFGLEVVE
HHHHHHHCCHHHCCHHHHHHHHHCCCCCEEEECCCCCEEEEECCCHHHHCCCCCHHHHHH
YLECHAGEGVRSVPPSAVP
HHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNFAPVPELIEELRAGRMVVIVDDEDRENEGDLIMAAELVKPSDINFMVTHARGLVCLSL
CCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCEEEEEECCCCCCCCEEEECCCCEEEEHH
TRERCAQLGLAPMVRNNTAQFQTNFTVSIEAAEGVTTGISAYDRAHTVRTAVRPDARPQD
HHHHHHHCCCCHHHCCCCEEEEEEEEEEEECCCCCHHCHHHHHHHHHHHHHCCCCCCCCC
LSQPGHIFPLISQPGGVLTRAGHTEAASDLPMLAGLEPAGVLVEVLNPDGSMARRPQLEV
CCCCCCEEEEECCCCCEEEECCCCCCCCCCCHHCCCCCCCEEEEEECCCCCCCCCCCHHH
FAREHGLKMGSIADLIAYRLANEHTVERVDEREITTEFGPFKLVTYRDRIAHDLHFALLR
HHHHHCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHH
GRADPQTPTLVRVQVENPLADLLHWQRDDFGVAATDALRAIAAEGQGVMVVLSAPRDSES
CCCCCCCCCEEEEEECCCHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHH
LLARLRQQPEAAANAKDVSQWRRNGAGAQILADLGLGKLRVLGTPRRQVGLAGFGLEVVE
HHHHHHHCCHHHCCHHHHHHHHHCCCCCEEEECCCCCEEEEECCCHHHHCCCCCHHHHHH
YLECHAGEGVRSVPPSAVP
HHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1339274 [H]