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The map label for this gene is emrK [H]

Identifier: 21241412

GI number: 21241412

Start: 755145

End: 756233

Strand: Reverse

Name: emrK [H]

Synonym: XAC0641

Alternate gene names: 21241412

Gene position: 756233-755145 (Counterclockwise)

Preceding gene: 21241413

Following gene: 21241411

Centisome position: 14.61

GC content: 67.68

Gene sequence:

>1089_bases
ATGAATACACCAGCAGATTCCTCCCCGCCTGCCGACCGGCAACGTCGTCGGCGTCGCCGTCTCGCCGGGGTCATTGGCTT
CGGCGGGCTCGCCCTGATCGGCGTGGCGCTGGTGCTATATGCCTGGCGGTTGCCGCCGTTCGTCAGTGCGATCGAACGCA
CCGAAAATGCGATGGTGCACGGTCAGATCACCGTGATTGCGCCGCAGGTGAGCGGCTATGTCACGCAGGTGCCGGTGCAG
GACTTTGCGCACGTCAAGCGCGGCCAGCTGCTGGCACGCATCGACGACCGCATCTATGCCCAGCAACTCGAACAGGCCAA
GGCGCAAGTGCAGACCGCGCAGGCCAACCTCGCCAACTGGGATCAACAACGGCATAGCGCCGAAGCGACGATTGCCGAGC
AACGCGCGGCGCTGAGCAGCAACCAGGCACAACGCGACCGCACCCGTTCGGCCTATGCACGGACGCAGCAGCTGGCCAGC
CAGCAACTGGTCTCCGAACAGGACCGCGACACCGCATTCGCCGCGCGCGCGCAGGCCGAGGCCGGCGTGGCGCAGGCACG
TGCCGCAGTGCAGGCCGCCGAAGAAAACGCGCGCGGCGTGACCGTCAACCGCGCCGCGTTGGAAGCCGCGGTTGCCAACG
CGCAGGCCGCCGTGCAGCTGGCACGGATCAACCTGGACAACACGCGCATCCTGGCCCCGCGCGATGGCCAGCTCGGTCAG
CTTGGCGTGCGCCAGGGCGCCTACGTCACCAACGGCACGCAGCTGATGTCGCTGGTGCCGGACACGCTGTGGATCGTGGC
CAATTTCAAGGAAACCCAGATGGCCCGGATCCGGATCGGCCAGCGCGCCAGCTTCACCGTGGATGCACTGGACAATGCGC
GTCTGCATGGCCGCGTGCAGGACATTTCGCCGGCTGCCGGCTCCGAATTCAGCGTGCTGCCGGCCGATAACGCCACCGGC
AACTTCGTCAAGATTGCCCAGCGCATTCCGCTGCGCATCAGCGTCGACCCGGACCAGCCGCTGGCGCCGCGGCTGCGGCC
GGGCATGTCGGTGGTGGTGGCCGTCGATACCGACAGCGCGGTCGACTAG

Upstream 100 bases:

>100_bases
TCGCCATCGCCACCGGCGTGTGGATCCTGTCCGTGCTGGTGTGGCGCCGCTATCTGCGGCCCTCGGTATCGCCCTCCCCT
CCTGCTCCCACTGCGCGCCC

Downstream 100 bases:

>100_bases
GCACAACCTGCCCCCGAGCGTGGGCAGCAATGCCGTCGCACGCAGGCGGGTCGGCCAGTACCCCCACCGGCATGACGTCG
CAGCTCAACCGCGGCACAGC

Product: multidrug resistance efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MNTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVHGQITVIAPQVSGYVTQVPVQ
DFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANWDQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLAS
QQLVSEQDRDTAFAARAQAEAGVAQARAAVQAAEENARGVTVNRAALEAAVANAQAAVQLARINLDNTRILAPRDGQLGQ
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQDISPAAGSEFSVLPADNATG
NFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSAVD

Sequences:

>Translated_362_residues
MNTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVHGQITVIAPQVSGYVTQVPVQ
DFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANWDQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLAS
QQLVSEQDRDTAFAARAQAEAGVAQARAAVQAAEENARGVTVNRAALEAAVANAQAAVQLARINLDNTRILAPRDGQLGQ
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQDISPAAGSEFSVLPADNATG
NFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSAVD
>Mature_362_residues
MNTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVHGQITVIAPQVSGYVTQVPVQ
DFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANWDQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLAS
QQLVSEQDRDTAFAARAQAEAGVAQARAAVQAAEENARGVTVNRAALEAAVANAQAAVQLARINLDNTRILAPRDGQLGQ
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQDISPAAGSEFSVLPADNATG
NFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSAVD

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=351, Percent_Identity=33.9031339031339, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1789041, Length=355, Percent_Identity=32.9577464788732, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1790519, Length=321, Percent_Identity=28.3489096573209, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI87081951, Length=337, Percent_Identity=26.4094955489614, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1789637, Length=316, Percent_Identity=25.6329113924051, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI87081796, Length=307, Percent_Identity=27.3615635179153, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790024, Length=287, Percent_Identity=26.4808362369338, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1790012, Length=245, Percent_Identity=25.7142857142857, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787013, Length=269, Percent_Identity=26.7657992565056, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 39125; Mature: 39125

Theoretical pI: Translated: 10.64; Mature: 10.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVH
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEE
GQITVIAPQVSGYVTQVPVQDFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANW
EEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLASQQLVSEQDRDTAFAARAQAE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AGVAQARAAVQAAEENARGVTVNRAALEAAVANAQAAVQLARINLDNTRILAPRDGQLGQ
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHEEEEEECCCCCEEECCCCCCCCC
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQ
HHCCCCCEEECCHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCEEEECCCCCHHCCEEE
DISPAAGSEFSVLPADNATGNFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSA
CCCCCCCCCEEEEECCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEEEECCCCC
VD
CC
>Mature Secondary Structure
MNTPADSSPPADRQRRRRRRLAGVIGFGGLALIGVALVLYAWRLPPFVSAIERTENAMVH
CCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCEEE
GQITVIAPQVSGYVTQVPVQDFAHVKRGQLLARIDDRIYAQQLEQAKAQVQTAQANLANW
EEEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQQRHSAEATIAEQRAALSSNQAQRDRTRSAYARTQQLASQQLVSEQDRDTAFAARAQAE
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AGVAQARAAVQAAEENARGVTVNRAALEAAVANAQAAVQLARINLDNTRILAPRDGQLGQ
HHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHEEEEEECCCCCEEECCCCCCCCC
LGVRQGAYVTNGTQLMSLVPDTLWIVANFKETQMARIRIGQRASFTVDALDNARLHGRVQ
HHCCCCCEEECCHHHHHHCCCEEEEEECCCHHHHHHHCCCCCCCEEEECCCCCHHCCEEE
DISPAAGSEFSVLPADNATGNFVKIAQRIPLRISVDPDQPLAPRLRPGMSVVVAVDTDSA
CCCCCCCCCEEEEECCCCCCCHHHHHHHCCEEEEECCCCCCCCCCCCCCEEEEEECCCCC
VD
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]