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The map label for this gene is aspC [C]

Identifier: 21241401

GI number: 21241401

Start: 744574

End: 745758

Strand: Reverse

Name: aspC [C]

Synonym: XAC0630

Alternate gene names: 21241401

Gene position: 745758-744574 (Counterclockwise)

Preceding gene: 21241410

Following gene: 77748544

Centisome position: 14.41

GC content: 65.57

Gene sequence:

>1185_bases
ATGGATTCCTTACTTCAGTACGCAGGCGGCTATAGCCGCCGCAGCCAGGACATCGCCCCGTTTCATGTCATGTCGCTGCT
GGCGCGCGCCAATGCGCTCGAGCAGGCCGGCCACGACGTGATCCACCTGGAAATCGGCGAGCCCGATTTCACCACTGCCG
CGCCCATCGTCGCTGCCGGCCAGGCGGCATTGGCGGCCGGCCACACCCGCTACACCGCCGCACGCGGGCTGCCGGCGCTG
CGCGAGGCGATTGCCGGCTTCTATGCGCAACGCTACGCCTGCAACCTCGATCCGGAGCGGATCCTGGTGACACCCGGGGG
GTCTGGCGCATTGCTGCTGGCCAGCAGCCTGCTGGTGGATCCGGGCAGGCATTGGTTGCTCGCCGACCCGGGCTACCCCT
GCAACCGCCACTTTCTGCGCCTGGTCGAGGGCGCCGCGCAATTGGTCCCGGTCGGCCCGGACAGCGATTATCAGTTGACC
CCTGCGCTGGTGGAGAGCGCCTGGAACGCCGACAGCGTGGGCGCCCTGGTGGCCTCGCCGGCAAACCCCACCGGCAGCGT
GCTGTCGCGCACGCAACTGGCTGCGCTTTCGCAGGCGCTGCATGCGCGCGGCGGCCACCTGGTGGTGGACGAGATCTACC
ACGGCCTGACCTACGGCCTGGATGCGCACAGCGTGCTGGAAGTGGACGATGGCGCGTTCGTGCTGAACAGTTTTTCCAAG
TATTTCGGCATGACGGGGTGGCGGCTGGGCTGGCTGATCGCACCGCCCGACGCGGTGCCGGAATTGGAAAAGCTCGCGCA
GAATCTGTACATCAGCGCCTCGACAATTGCCCAGCACGCCGCACTGGCCTGCTTCACGCCCGAGAGCATTGCCCTCTTCG
AAGCGCGCCGCGCCGAGTTCCAGCAGCGTCGCGATTACCTGCTGCCGGCCTTGCGTGCGCTGGGATTCGAGATCGCGGTC
GAACCGCAAGGCGCGTTTTACTTGTATGCCGACATCAGCGGATTTTCAGATGATGCGCAGGCGTTTTGCGCGCATTTTCT
GGAGACCGAACATGTTGCGTTTACGCCCGGCATCGACTTCGGCCACTACCGCGCCAATCAGCATGTACGCATTGCCTACA
CGCAAAGCCTGCCGCGCCTGCAGCAGGCGGTAGAGCGAATTGCGCGTGGGTTGAAGCGGTTGTAG

Upstream 100 bases:

>100_bases
GTCCATTGGATGAACGCAATGCCATCCCAGCACCCGAGTGTGGAAGAGCCTTCTGTCGGGCGCCATGTGTCCTAGGTCAT
GCTGGTCTATCATCGAACCA

Downstream 100 bases:

>100_bases
ATCGACATTGCGTAGCCGCAAGTTAGCCCGCCAGCATCGCGCCCGGAACGCAGCATCGCTCGGCTGAAAGAGGGCGTACG
ACAATCATCTAGGTGCGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MDSLLQYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAGQAALAAGHTRYTAARGLPAL
REAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVDPGRHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLT
PALVESAWNADSVGALVASPANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIALFEARRAEFQQRRDYLLPALRALGFEIAV
EPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDFGHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL

Sequences:

>Translated_394_residues
MDSLLQYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAGQAALAAGHTRYTAARGLPAL
REAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVDPGRHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLT
PALVESAWNADSVGALVASPANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIALFEARRAEFQQRRDYLLPALRALGFEIAV
EPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDFGHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL
>Mature_394_residues
MDSLLQYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAGQAALAAGHTRYTAARGLPAL
REAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVDPGRHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLT
PALVESAWNADSVGALVASPANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIALFEARRAEFQQRRDYLLPALRALGFEIAV
EPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDFGHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=325, Percent_Identity=28.6153846153846, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI169881279, Length=325, Percent_Identity=28.6153846153846, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI56713254, Length=326, Percent_Identity=26.3803680981595, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI56713256, Length=326, Percent_Identity=26.3803680981595, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI169881281, Length=212, Percent_Identity=26.4150943396226, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI4507369, Length=402, Percent_Identity=23.3830845771144, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI149944424, Length=206, Percent_Identity=29.6116504854369, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788722, Length=390, Percent_Identity=27.4358974358974, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1786816, Length=384, Percent_Identity=28.125, Blast_Score=108, Evalue=6e-25,
Organism=Escherichia coli, GI1788627, Length=386, Percent_Identity=26.4248704663212, Blast_Score=90, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=379, Percent_Identity=25.3298153034301, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=379, Percent_Identity=25.3298153034301, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=25.065963060686, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17567369, Length=304, Percent_Identity=23.6842105263158, Blast_Score=72, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=389, Percent_Identity=22.3650385604113, Blast_Score=83, Evalue=8e-17,
Organism=Drosophila melanogaster, GI28573069, Length=285, Percent_Identity=27.0175438596491, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI24646114, Length=285, Percent_Identity=27.0175438596491, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28573067, Length=285, Percent_Identity=27.0175438596491, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI28573065, Length=285, Percent_Identity=27.0175438596491, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI18859735, Length=376, Percent_Identity=24.2021276595745, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42612; Mature: 42612

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDSLLQYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAG
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCC
QAALAAGHTRYTAARGLPALREAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVD
CHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCC
PGRHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLTPALVESAWNADSVGALVASP
CCCCEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCEECHHHHHCCCCCCCCCCEEECC
ANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
CCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHH
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIALFEARRAEF
HHCCCCCEEEEEECCCCCCHHHHHHHHHHEECHHHHHHHHEEEEECCCHHHHHHHHHHHH
QQRRDYLLPALRALGFEIAVEPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDF
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCC
GHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL
CCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDSLLQYAGGYSRRSQDIAPFHVMSLLARANALEQAGHDVIHLEIGEPDFTTAAPIVAAG
CCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHCC
QAALAAGHTRYTAARGLPALREAIAGFYAQRYACNLDPERILVTPGGSGALLLASSLLVD
CHHHHCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHCC
PGRHWLLADPGYPCNRHFLRLVEGAAQLVPVGPDSDYQLTPALVESAWNADSVGALVASP
CCCCEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCEECHHHHHCCCCCCCCCCEEECC
ANPTGSVLSRTQLAALSQALHARGGHLVVDEIYHGLTYGLDAHSVLEVDDGAFVLNSFSK
CCCCHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHH
YFGMTGWRLGWLIAPPDAVPELEKLAQNLYISASTIAQHAALACFTPESIALFEARRAEF
HHCCCCCEEEEEECCCCCCHHHHHHHHHHEECHHHHHHHHEEEEECCCHHHHHHHHHHHH
QQRRDYLLPALRALGFEIAVEPQGAFYLYADISGFSDDAQAFCAHFLETEHVAFTPGIDF
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEECCCCCC
GHYRANQHVRIAYTQSLPRLQQAVERIARGLKRL
CCCCCCCEEEEEEHHCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]