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The map label for this gene is ywbI [H]

Identifier: 21241279

GI number: 21241279

Start: 595808

End: 596710

Strand: Reverse

Name: ywbI [H]

Synonym: XAC0508

Alternate gene names: 21241279

Gene position: 596710-595808 (Counterclockwise)

Preceding gene: 21241281

Following gene: 21241278

Centisome position: 11.53

GC content: 70.54

Gene sequence:

>903_bases
ATGCTGACCTTGCGCCAACTGGAATTTGCCGTGGCCGTGGCCGAAGAAGGCGGTTTCACCGCCGCTGCGCGCCGCTGCAA
CACCGTGCAGTCGGCGCTCAGCCACCAGGTCGCCAAGATCGAAGAGACCTTCGGTGCACGCCTGTTCGAACGCGGCACCC
GCCGGGTGCGGCCCACCGCCGCCGGCGAGGTGCTCCTGCACAACGCCCGCCAGACCCTGCGCGCTGCCGAGCGCCTGCAC
GAGGAAATGGCGCAGGCCCTGGGCACCGTGCGCGGGCGGTTGGCGTTGGGGCAGATTTCCTCGCTCACCACCGTGCAACT
GCCGGCCTTGCTGCATCAGTTCCGCAGCGCGCATGCGCGGGTGGACGTGCATCTGCGCACTGCCATGAGCGAGGCGTTGC
TGCACGATCTGGGCGAAGGCCGGCTGGATGTCGCCCTGGTCGGTGTCGGCCCGCAGCTTGCGGTGCCGGCGCAGCGCCTG
CTGCTGCATGAAGAGGCGCTGGCCTTGATCGTGGCCCCCGGCCACCGCCTTGCTGCGCGCAAGCGGGTGGCGCTGGCCGA
GCTGGACGACGAACCGATGGCCGGGCTGGTTCCCGGCGCCGGCGTGCGCGGCATCATCGATGCCGCCTTCGCCCAGTCCG
GCCTGCGGCAGCGCCAGCAGTACGAAGTCACCCATGCCGATCTGGTGCGCGAACTGGTCGCTGCCAACCTGGGCGTAGGC
ATCGTCCCGCAGACCATGGCCGGCGCCATGCGCGGCGTGATCACGGTGGCCTTGAAGGAGCGCTACCGCTTTCTGACCTA
TGCGGTGTGGCGGCCCGACCCCAGCCCGGCCGCACGCGCCTTCGTGGCCTTGCTGCGCGCCCAACTCGCGCAACGCAGGC
CACCGGCACAGAGAAGCCGCTGA

Upstream 100 bases:

>100_bases
CATGGCGGCTGTCTGGTCAAGGAATGCGCACAGTGTGGGCAGCCGGCACACATCTCTCCAATGTATTGTTTTCACTATCG
CCATCTTTTTTCGAGATTGC

Downstream 100 bases:

>100_bases
GCGCAACCGCCATCCACCAGCACGCCATGGAAGCCTGCTAGGCTGCGCGCGTTCGCAAAGGAAACTGCATGTCCGGTCAC
AGCCAGTTCGCCCTGCTCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MLTLRQLEFAVAVAEEGGFTAAARRCNTVQSALSHQVAKIEETFGARLFERGTRRVRPTAAGEVLLHNARQTLRAAERLH
EEMAQALGTVRGRLALGQISSLTTVQLPALLHQFRSAHARVDVHLRTAMSEALLHDLGEGRLDVALVGVGPQLAVPAQRL
LLHEEALALIVAPGHRLAARKRVALAELDDEPMAGLVPGAGVRGIIDAAFAQSGLRQRQQYEVTHADLVRELVAANLGVG
IVPQTMAGAMRGVITVALKERYRFLTYAVWRPDPSPAARAFVALLRAQLAQRRPPAQRSR

Sequences:

>Translated_300_residues
MLTLRQLEFAVAVAEEGGFTAAARRCNTVQSALSHQVAKIEETFGARLFERGTRRVRPTAAGEVLLHNARQTLRAAERLH
EEMAQALGTVRGRLALGQISSLTTVQLPALLHQFRSAHARVDVHLRTAMSEALLHDLGEGRLDVALVGVGPQLAVPAQRL
LLHEEALALIVAPGHRLAARKRVALAELDDEPMAGLVPGAGVRGIIDAAFAQSGLRQRQQYEVTHADLVRELVAANLGVG
IVPQTMAGAMRGVITVALKERYRFLTYAVWRPDPSPAARAFVALLRAQLAQRRPPAQRSR
>Mature_300_residues
MLTLRQLEFAVAVAEEGGFTAAARRCNTVQSALSHQVAKIEETFGARLFERGTRRVRPTAAGEVLLHNARQTLRAAERLH
EEMAQALGTVRGRLALGQISSLTTVQLPALLHQFRSAHARVDVHLRTAMSEALLHDLGEGRLDVALVGVGPQLAVPAQRL
LLHEEALALIVAPGHRLAARKRVALAELDDEPMAGLVPGAGVRGIIDAAFAQSGLRQRQQYEVTHADLVRELVAANLGVG
IVPQTMAGAMRGVITVALKERYRFLTYAVWRPDPSPAARAFVALLRAQLAQRRPPAQRSR

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=279, Percent_Identity=28.673835125448, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1787879, Length=310, Percent_Identity=33.8709677419355, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI157672245, Length=257, Percent_Identity=29.9610894941634, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1788887, Length=294, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787530, Length=243, Percent_Identity=25.1028806584362, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787806, Length=274, Percent_Identity=25.9124087591241, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI2367136, Length=268, Percent_Identity=26.865671641791, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI145693105, Length=294, Percent_Identity=27.891156462585, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1789204, Length=244, Percent_Identity=27.0491803278689, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI87081904, Length=253, Percent_Identity=28.8537549407115, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788748, Length=249, Percent_Identity=25.7028112449799, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=28.2485875706215, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1790262, Length=270, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788297, Length=262, Percent_Identity=25.1908396946565, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=27.0161290322581, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87082132, Length=255, Percent_Identity=25.4901960784314, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32558; Mature: 32558

Theoretical pI: Translated: 11.55; Mature: 11.55

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLRQLEFAVAVAEEGGFTAAARRCNTVQSALSHQVAKIEETFGARLFERGTRRVRPTA
CCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AGEVLLHNARQTLRAAERLHEEMAQALGTVRGRLALGQISSLTTVQLPALLHQFRSAHAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDVHLRTAMSEALLHDLGEGRLDVALVGVGPQLAVPAQRLLLHEEALALIVAPGHRLAAR
EEHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCHHHHHH
KRVALAELDDEPMAGLVPGAGVRGIIDAAFAQSGLRQRQQYEVTHADLVRELVAANLGVG
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IVPQTMAGAMRGVITVALKERYRFLTYAVWRPDPSPAARAFVALLRAQLAQRRPPAQRSR
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MLTLRQLEFAVAVAEEGGFTAAARRCNTVQSALSHQVAKIEETFGARLFERGTRRVRPTA
CCCHHHHHHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
AGEVLLHNARQTLRAAERLHEEMAQALGTVRGRLALGQISSLTTVQLPALLHQFRSAHAR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VDVHLRTAMSEALLHDLGEGRLDVALVGVGPQLAVPAQRLLLHEEALALIVAPGHRLAAR
EEHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHEEEECCCHHHHHH
KRVALAELDDEPMAGLVPGAGVRGIIDAAFAQSGLRQRQQYEVTHADLVRELVAANLGVG
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IVPQTMAGAMRGVITVALKERYRFLTYAVWRPDPSPAARAFVALLRAQLAQRRPPAQRSR
CCCHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]