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The map label for this gene is mrpG [H]

Identifier: 21241230

GI number: 21241230

Start: 546669

End: 547088

Strand: Reverse

Name: mrpG [H]

Synonym: XAC0457

Alternate gene names: 21241230

Gene position: 547088-546669 (Counterclockwise)

Preceding gene: 21241231

Following gene: 21241228

Centisome position: 10.57

GC content: 62.38

Gene sequence:

>420_bases
ATGATCGCCTTCACCGAATACCTACTCAGCGCCTTGCTGCTGGCGGGCACGTTCTTCATCCTGATCGGCGCTTTTGGCCT
GGTGAAGCTGTCGGATTTTTTCAAGCGCCTGCATGCACCGACCAAGGCGAGCACGCTGGGCGTGGGCTGCGTGCTGCTGG
CCTCGGTGGGCTACCACCTGTTTCTGGGTGTGGACCCGCAACCGCGCGAATTGCTGATCACCGTGTTCCTGTTCATCACC
GCACCGATCAGCGCGCACTTGATGGCCAAGGCGGCGCTGTCGCTGATGATGGAAGACCGCCCGGAAGTGCCGAACCACGG
CGACGCGCAGCAGGAAGGGTTGCCGCAGGTCAAAGGCGATGTTGGCGAGAACGAAGACACCGAGAAGCAGCATCCGGGGC
CTGCGTCGGAGGGTGGCTAA

Upstream 100 bases:

>100_bases
ATTCACCGATCTATTTCGAGGCTGCCCTGGTCATTGCGATGCTGGGCTTCGGCAGCACCGTGGTGCTGAGCAAATACGTG
CTGCGGCGGAGCATCGTCGA

Downstream 100 bases:

>100_bases
GGCGTTGTTGCTCGGCCTGGATGGCTTACGATCAGATTCCGCACCTGCTCAGCACCTTCTCAACGGCGCGACCAGCTGAC
GCGGTAGTCAGCGCATGACG

Product: monovalent cation/H+ antiporter subunit G

Products: NA

Alternate protein names: Mrp complex subunit G; Multiple resistance and pH homeostasis protein G [H]

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MIAFTEYLLSALLLAGTFFILIGAFGLVKLSDFFKRLHAPTKASTLGVGCVLLASVGYHLFLGVDPQPRELLITVFLFIT
APISAHLMAKAALSLMMEDRPEVPNHGDAQQEGLPQVKGDVGENEDTEKQHPGPASEGG

Sequences:

>Translated_139_residues
MIAFTEYLLSALLLAGTFFILIGAFGLVKLSDFFKRLHAPTKASTLGVGCVLLASVGYHLFLGVDPQPRELLITVFLFIT
APISAHLMAKAALSLMMEDRPEVPNHGDAQQEGLPQVKGDVGENEDTEKQHPGPASEGG
>Mature_139_residues
MIAFTEYLLSALLLAGTFFILIGAFGLVKLSDFFKRLHAPTKASTLGVGCVLLASVGYHLFLGVDPQPRELLITVFLFIT
APISAHLMAKAALSLMMEDRPEVPNHGDAQQEGLPQVKGDVGENEDTEKQHPGPASEGG

Specific function: Mrp complex is a Na(+)/H(+) antiporter that is considered to be the major Na(+) excretion system in B.subtilis. Has a major role in Na(+) resistance and a minor role in Na(+)- and K(+)-dependent pH homeostasis as compared to TetB. MrpA may be the actual N

COG id: COG1320

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhG subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit G family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005133 [H]

Pfam domain/function: PF03334 PhaG_MnhG_YufB [H]

EC number: NA

Molecular weight: Translated: 14874; Mature: 14874

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAFTEYLLSALLLAGTFFILIGAFGLVKLSDFFKRLHAPTKASTLGVGCVLLASVGYHL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHE
FLGVDPQPRELLITVFLFITAPISAHLMAKAALSLMMEDRPEVPNHGDAQQEGLPQVKGD
EECCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCC
VGENEDTEKQHPGPASEGG
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MIAFTEYLLSALLLAGTFFILIGAFGLVKLSDFFKRLHAPTKASTLGVGCVLLASVGYHL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHE
FLGVDPQPRELLITVFLFITAPISAHLMAKAALSLMMEDRPEVPNHGDAQQEGLPQVKGD
EECCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCCCCCCCC
VGENEDTEKQHPGPASEGG
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9274030; 9384377; 10198001; 11356194 [H]