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The map label for this gene is glpR [H]

Identifier: 21241135

GI number: 21241135

Start: 431189

End: 431959

Strand: Reverse

Name: glpR [H]

Synonym: XAC0361

Alternate gene names: 21241135

Gene position: 431959-431189 (Counterclockwise)

Preceding gene: 21241136

Following gene: 21241134

Centisome position: 8.35

GC content: 66.28

Gene sequence:

>771_bases
TTGAACCCGCGTCAGGAGCAATTGGTGGCGCTGGTGCGGCAGCAGGGCTTTGCCGAGGTCGAAGGTTTGGCCACACGCTT
CGAGGTGACGCCGCAGACCATCCGCCGCGATCTGACCTTGCTCTGCGATGCCGGCGTGCTGCGCCGCTATCACGGCGGCG
TCAGCATGCCCTCCAGCGTGGAGAATCTGGCCTACACCGCACGCAAGGCACTGCAGGCCCGCGAAAAGCAGCACATCGCC
GCGCGTGTCGCGCGTTTCATTCCCGACGATGCCTCGCTGTTCATCAACCTGGGCACCACCAACGAAGAAGTCGCACGCGC
GTTGCTGCAGCACCGCGGACTCCGGGTGATCACCAACAACCTCAACGTGGCGGTGATGCTCAGCGCCAACCCCAGCTTCG
AGGTGATCGTGGCCGGCGGCGTGGTGCGCGGGCGCGACCAGGGCGTGACCGGCGAGGCGACGGTGGAGCTGATCCGCCAG
TTCAAGGTGGACTTCGGGGTGATCGGCATTTCCGGTATCGATCTGGACGGCACCCTGCTGGATTTCGATTACCAGGAAGT
GCGCGTGGCGCAGGCCATCATCGAACACTCGCGACACGTGCTGCTGGCCGCCGATCACAGCAAGTTCGGTCGCAACGCCA
TGGTGCGGCTGGGCGCCATCGCGCAGGTGCACGACTGGTTTACCGACCGGCCGCCGCCGCAGGAGTTGGCGAGCGTGCTG
GCCGAGGCCGGCACCCGGGTGCACCTGGCAGACGCGGACGGAACCGATTGA

Upstream 100 bases:

>100_bases
CGCTGGCGGCACGCACGCGCGCGTGTTTTGCATCCTCACGCGCATGCGCGATCATCTGCGCATGGAGTCGACTCACTACA
GGACTGTCCCGGCGCCGGCC

Downstream 100 bases:

>100_bases
GGCCCATGTTCGTTTTTGAGCGTTTTTACGTGTCAGCTGCCAAAAGCCACTGTGCCTGATAGGTCCGCTACATATAAACC
TGTTTTCCCATAGCCGATCT

Product: glycerol-3-phosphate regulon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 256; Mature: 256

Protein sequence:

>256_residues
MNPRQEQLVALVRQQGFAEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSVENLAYTARKALQAREKQHIA
ARVARFIPDDASLFINLGTTNEEVARALLQHRGLRVITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQ
FKVDFGVIGISGIDLDGTLLDFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPQELASVL
AEAGTRVHLADADGTD

Sequences:

>Translated_256_residues
MNPRQEQLVALVRQQGFAEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSVENLAYTARKALQAREKQHIA
ARVARFIPDDASLFINLGTTNEEVARALLQHRGLRVITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQ
FKVDFGVIGISGIDLDGTLLDFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPQELASVL
AEAGTRVHLADADGTD
>Mature_256_residues
MNPRQEQLVALVRQQGFAEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSVENLAYTARKALQAREKQHIA
ARVARFIPDDASLFINLGTTNEEVARALLQHRGLRVITNNLNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQ
FKVDFGVIGISGIDLDGTLLDFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPQELASVL
AEAGTRVHLADADGTD

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=247, Percent_Identity=51.8218623481781, Blast_Score=268, Evalue=3e-73,
Organism=Escherichia coli, GI87082344, Length=253, Percent_Identity=41.501976284585, Blast_Score=216, Evalue=1e-57,
Organism=Escherichia coli, GI1788069, Length=232, Percent_Identity=30.6034482758621, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1789059, Length=250, Percent_Identity=28.8, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789519, Length=252, Percent_Identity=26.984126984127, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790753, Length=250, Percent_Identity=26.8, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI226510968, Length=240, Percent_Identity=26.25, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1787540, Length=231, Percent_Identity=29.4372294372294, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=23.7068965517241, Blast_Score=64, Evalue=9e-12,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28021; Mature: 28021

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPRQEQLVALVRQQGFAEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSV
CCCHHHHHHHHHHHCCHHHHHHHHHHEECCHHHHHHHHHHHHCHHHHHHHCCCCCCCHHH
ENLAYTARKALQAREKQHIAARVARFIPDDASLFINLGTTNEEVARALLQHRGLRVITNN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEECC
LNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQFKVDFGVIGISGIDLDGTLL
CCEEEEEECCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCEEE
DFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPQELASVL
CCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AEAGTRVHLADADGTD
HHCCCEEEEECCCCCC
>Mature Secondary Structure
MNPRQEQLVALVRQQGFAEVEGLATRFEVTPQTIRRDLTLLCDAGVLRRYHGGVSMPSSV
CCCHHHHHHHHHHHCCHHHHHHHHHHEECCHHHHHHHHHHHHCHHHHHHHCCCCCCCHHH
ENLAYTARKALQAREKQHIAARVARFIPDDASLFINLGTTNEEVARALLQHRGLRVITNN
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHCCCEEEECC
LNVAVMLSANPSFEVIVAGGVVRGRDQGVTGEATVELIRQFKVDFGVIGISGIDLDGTLL
CCEEEEEECCCCEEEEEECCEEECCCCCCCHHHHHHHHHHHHHCEEEEEEECCCCCCEEE
DFDYQEVRVAQAIIEHSRHVLLAADHSKFGRNAMVRLGAIAQVHDWFTDRPPPQELASVL
CCCHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
AEAGTRVHLADADGTD
HHCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]