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The map label for this gene is glpD [H]

Identifier: 21241134

GI number: 21241134

Start: 429451

End: 430956

Strand: Reverse

Name: glpD [H]

Synonym: XAC0360

Alternate gene names: 21241134

Gene position: 430956-429451 (Counterclockwise)

Preceding gene: 21241135

Following gene: 21241133

Centisome position: 8.33

GC content: 67.33

Gene sequence:

>1506_bases
ATGTACGATCTTCTGGTAATCGGCGGCGGCATCAACGGGGTGGGCATTGCCCGTGATGCGGCCGGGCGCGGTCTGTCGGT
GTGCCTGTGCGAGCAGGACGACCTGGCTGCGCACACCAGCAGCGCCAGCACCAAACTCATTCACGGCGGCCTGCGCTACC
TGGAGCAGTACGAATTCGCCTTGGTCGGCAAAGCACTGGCCGAGCGCGAAGTGTTGCTGCGGCTGGCCCCGCACATCATC
TGGCCGTTGCGCTTCCTGCTGCCCCACCAACCGCACCTGCGCCCGGCATGGATGATCCGCGCCGGGCTGTTCCTGTACGA
CCATCTGGGCGGCAGCAAGCGCAGCCTGCCGCGCTCGCGCCGGCTGTCGCTGCGGACGCACCCGGTCGGTGCGCCGCTGC
AGGAGTCGCTGCGCACCGGCTTCGTGTATTCGGATGCGTGGGTGCAGGACGCGCGACTGGTGGTGCTCAACGCGATGGAC
GCCGCCAGGCGCGGTGCCAAGATCCACACCCGCACGCGCTGTGTCGGTGCCTGGCGCGATGCGGGCTTCTGGTATGCCGA
GCTCGAAGACCGCCAGGGCCGCCGCCGCACCGTGCAGGCGCGTGCGCTCGCCAATGCCGCCGGCCCGTGGGCGGTGTCGT
TCCTGGACACCGTGGCCTCGGTGCCGCACGAACATGCATTGCGGCTGGTCAAGGGCAGCCACATCGTGGTGCCCAAGCTG
TTCGATCACGACCATGCGTACATCTTCCAGCAACCGGACCGGCGCATCGTGTTCGCCATCCCCTACGAGCACGACTTCAC
CTTGATCGGCACCACCGACGTGGACTACGAAGCCGACCCCGCCGCGCCGAAGATCGATGCGGCCGAAGTGCAATACCTGT
GCGATGCGGTGAACCTGTATTTCCAGCAGCAGATCTCCCCCGCCGATGTGGTGTGGAATTACAGCGGCGTGCGGCCGTTG
CTGGACGATGCCGAAGACAACGCAGCCGAAGTGACCCGCGATTACCAGCTGGAAGTGGTCACCGAGGGCGCGCCGTTGCT
CAACGTGTTCGGCGGCAAGCTGACCACCTATCGCAAGCTCGCCGAAGAGGCAGTGGACCGGCTTACCCACGCGCTGGGCA
CACGCAAGCCTGCGTGGACCGCGCGTGGCGAGGCATTACCAGGCGGCGAGCAGCGCGATATCGCCAGCCTGCTGGAACGC
GTCGGCCGCGCGCGCCCCTGGCTACCGGCAGCGACCGCGCAGCGGCTGGTGCGCAACTACGGCACCTGCGCCGAACACCT
GCTTGGCGATGCGCAGAGCCTGACCGATCTGGGCACGCACTTCGGCGCGGACCTGTATCAGGCCGAGGTGGATTACCTGC
GCCAACACGAATGGGCGGTGGCGGCCGACGATATCCTGTGGCGGCGCAGCAAGCTCGGCCTGCGGATCGATGCGGCCGGG
CGGCAGCGCCTGGAAGACTATCTGCAGACGCAGTCGATCCGGCAACGCGACGTCGTTTCTGCTTGA

Upstream 100 bases:

>100_bases
CATCTTCACGTCTCCGCAAGGTTCGATGTTCGAATATGTTCGAACATGACAACTTGGGTTCGCTCATCGGCGCACCCTGA
CGGAGGCACCGATGGGCGAG

Downstream 100 bases:

>100_bases
ACACACCGCGTTGCCGGCGAGGACGGGTCGCCCGGCAGCGTATTCCGGCGCTTCAGCCAGCATCACCTGAGTCACGTGGA
GGGCACCCCAGATGAGCATC

Product: glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFALVGKALAEREVLLRLAPHII
WPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSRRLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLNAMD
AARRGAKIHTRTRCVGAWRDAGFWYAELEDRQGRRRTVQARALANAAGPWAVSFLDTVASVPHEHALRLVKGSHIVVPKL
FDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAVNLYFQQQISPADVVWNYSGVRPL
LDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTYRKLAEEAVDRLTHALGTRKPAWTARGEALPGGEQRDIASLLER
VGRARPWLPAATAQRLVRNYGTCAEHLLGDAQSLTDLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRIDAAG
RQRLEDYLQTQSIRQRDVVSA

Sequences:

>Translated_501_residues
MYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFALVGKALAEREVLLRLAPHII
WPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSRRLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLNAMD
AARRGAKIHTRTRCVGAWRDAGFWYAELEDRQGRRRTVQARALANAAGPWAVSFLDTVASVPHEHALRLVKGSHIVVPKL
FDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAVNLYFQQQISPADVVWNYSGVRPL
LDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTYRKLAEEAVDRLTHALGTRKPAWTARGEALPGGEQRDIASLLER
VGRARPWLPAATAQRLVRNYGTCAEHLLGDAQSLTDLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRIDAAG
RQRLEDYLQTQSIRQRDVVSA
>Mature_501_residues
MYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFALVGKALAEREVLLRLAPHII
WPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSRRLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLNAMD
AARRGAKIHTRTRCVGAWRDAGFWYAELEDRQGRRRTVQARALANAAGPWAVSFLDTVASVPHEHALRLVKGSHIVVPKL
FDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAVNLYFQQQISPADVVWNYSGVRPL
LDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTYRKLAEEAVDRLTHALGTRKPAWTARGEALPGGEQRDIASLLER
VGRARPWLPAATAQRLVRNYGTCAEHLLGDAQSLTDLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRIDAAG
RQRLEDYLQTQSIRQRDVVSA

Specific function: Conversion Of Glycerol 3-Phosphate To Dihydroxyacetone. Uses Molecular Oxygen Or Nitrate As Electron Acceptor. [C]

COG id: COG0578

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI285002233, Length=531, Percent_Identity=30.1318267419962, Blast_Score=166, Evalue=6e-41,
Organism=Homo sapiens, GI285002231, Length=531, Percent_Identity=30.1318267419962, Blast_Score=166, Evalue=6e-41,
Organism=Escherichia coli, GI2367226, Length=468, Percent_Identity=51.2820512820513, Blast_Score=465, Evalue=1e-132,
Organism=Escherichia coli, GI1788574, Length=395, Percent_Identity=28.8607594936709, Blast_Score=82, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI115534726, Length=515, Percent_Identity=31.0679611650485, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17509253, Length=413, Percent_Identity=32.2033898305085, Blast_Score=150, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6322036, Length=535, Percent_Identity=28.5981308411215, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI161077125, Length=526, Percent_Identity=30.4182509505703, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24653942, Length=526, Percent_Identity=30.4182509505703, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24653944, Length=526, Percent_Identity=30.4182509505703, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI20130025, Length=526, Percent_Identity=30.4182509505703, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI24586295, Length=454, Percent_Identity=29.7356828193833, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI19921278, Length=512, Percent_Identity=25.5859375, Blast_Score=100, Evalue=5e-21,
Organism=Drosophila melanogaster, GI45550977, Length=366, Percent_Identity=23.7704918032787, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR000447 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.1.5.3 [H]

Molecular weight: Translated: 55918; Mature: 55918

Theoretical pI: Translated: 7.32; Mature: 7.32

Prosite motif: PS00977 FAD_G3PDH_1 ; PS00978 FAD_G3PDH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFA
CCEEEEECCCCCCCEEECCCCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHH
LVGKALAEREVLLRLAPHIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHH
RLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLNAMDAARRGAKIHTRTRCVGAWRD
CCEEEECCCCCCHHHHHHCCCEEECCHHCCCEEEEEECHHHHHCCCCEEHHHHHHCCHHC
AGFWYAELEDRQGRRRTVQARALANAAGPWAVSFLDTVASVPHEHALRLVKGSHIVVPKL
CCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEE
FDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAVNLY
ECCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
FQQQISPADVVWNYSGVRPLLDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTYRKL
HHHCCCHHHEEECCCCCCHHHCCCCCCHHHHCCCEEEEEEECCCCCHHHCCCCHHHHHHH
AEEAVDRLTHALGTRKPAWTARGEALPGGEQRDIASLLERVGRARPWLPAATAQRLVRNY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GTCAEHLLGDAQSLTDLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRIDAAG
CHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCEEEEHHH
RQRLEDYLQTQSIRQRDVVSA
HHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYDLLVIGGGINGVGIARDAAGRGLSVCLCEQDDLAAHTSSASTKLIHGGLRYLEQYEFA
CCEEEEECCCCCCCEEECCCCCCCCEEEEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHH
LVGKALAEREVLLRLAPHIIWPLRFLLPHQPHLRPAWMIRAGLFLYDHLGGSKRSLPRSR
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHH
RLSLRTHPVGAPLQESLRTGFVYSDAWVQDARLVVLNAMDAARRGAKIHTRTRCVGAWRD
CCEEEECCCCCCHHHHHHCCCEEECCHHCCCEEEEEECHHHHHCCCCEEHHHHHHCCHHC
AGFWYAELEDRQGRRRTVQARALANAAGPWAVSFLDTVASVPHEHALRLVKGSHIVVPKL
CCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHCCCEEEEEEE
FDHDHAYIFQQPDRRIVFAIPYEHDFTLIGTTDVDYEADPAAPKIDAAEVQYLCDAVNLY
ECCCCEEEEECCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHH
FQQQISPADVVWNYSGVRPLLDDAEDNAAEVTRDYQLEVVTEGAPLLNVFGGKLTTYRKL
HHHCCCHHHEEECCCCCCHHHCCCCCCHHHHCCCEEEEEEECCCCCHHHCCCCHHHHHHH
AEEAVDRLTHALGTRKPAWTARGEALPGGEQRDIASLLERVGRARPWLPAATAQRLVRNY
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
GTCAEHLLGDAQSLTDLGTHFGADLYQAEVDYLRQHEWAVAADDILWRRSKLGLRIDAAG
CHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHCCEEEEHHH
RQRLEDYLQTQSIRQRDVVSA
HHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8157588; 10984043 [H]