Click here to switch to the map view.

The map label for this gene is smeB [H]

Identifier: 21241102

GI number: 21241102

Start: 389797

End: 392946

Strand: Direct

Name: smeB [H]

Synonym: XAC0328

Alternate gene names: 21241102

Gene position: 389797-392946 (Clockwise)

Preceding gene: 21241101

Following gene: 21241103

Centisome position: 7.53

GC content: 66.0

Gene sequence:

>3150_bases
ATGGCCCGTTTCTTCATCGACCGTCCCATCTTCGCCTGGGTCATCGCCATCGTGATCACCCTGGCCGGCGCGCTCTCGAT
CCTGTCGCTGCCGCTGGAGCAGTATCCCAACATCGCCCCACCGACGATCAACGTCAGCGCCACCTACACCGGCGCCTCGG
CGCAGACCGTACAGAACTCGGTGACGCAGATCCTCGAGCAGCAGATGACCGGCCTGGATCACCTGCTGTACATGTCCTCC
AGCAGCAGCTCGGCCGGTACCGCCTCGATCACCCTGACCTTCGAGTCCGGCACCGACCCGGACACCGCCCAGGTGCAGGT
GCAGAACAAGGTCTCGCAGGGCGAGGCGATGCTGCCGGAGGCGGTGCAGAGCAATGGCGTGACCGTCACCAAGTCCACCG
GCAGCAGCATGTTCATGGTGCTGGCCTTCACCTCCGAAGACGGCAGCATGGACAGCACCGACATCGGCGACTACATGGTG
TCCACGCTGCAGGACCCGATCAGCCGGCTCAACGGCGTTGGCGGGGTCAACGTGTTCGGCTCCGAATATGCGATGCGGGT
GTGGCTGGATCCGGAGAAGCTGCGCACCTATTCGCTGATGCCCGCGGACGTGAGCAACGCGATTTCGGCGCAGAACGCCG
ACGTCTCCTCGGGCGCGCTGGGCGCGTTGCCGGCGGTGCAGGGCCAGCAGCTCAACGCCACGGTCACCTCGCGCAGCAAG
CTCAAGACCCCGGCGCAATTCGAGGCGATCGTGCTGAAGTCGCAGCCCGGCGGCGCCACCGTGTATCTGCGCGACGTGGC
GCGGGTGGAGCTGGGTTCCAAGTCGTATGCATCCAGTTCCAAGTACAACGGCAAGTCGGCCTCGGGCATGGGCCTGGAGC
TGGCGACCGGCGCCAACGCGCTGGATGCGGCCAAGGCGGTGGAAGCCAAGCTCGAACAGCTTAAGCCGTACTTCCCCACC
GGGCTCACGTACGAAGTCGCCTACGACACCACGCCGTTCGTGCGTATTTCCATCGAGGAAGTGGTCAAGACCCTGCTCGA
GGCGATCGTGCTGGTAGTGCTGGTGATGTACCTGTTCCTGCAGAACTGGCGCGCCACGCTGGTGCCGGTGATCGCGGTGC
CGGTGGTGCTGCTGGGCACCTTCGGCGTGCTGGCCTTGCTCGGCTATTCGATCAACACGCTGACCATGTTCGCGATGGTG
CTGGCGATCGGCCTGCTGGTCGACGACGCCATCGTGGTGGTGGAGAACGTCGAGCGTCTGATGAGCGAGCAAGGCATGTC
GCCGCGGCAGGCGACCTACACCTCGATGGGACAGATCTCCGGCGCGCTGGTCGGCATCGCCCTGGTGCTGACCGCGGTGT
TCCTGCCGATGGCCTTCTTCGGCGGCGCCACCGGCGAGATCTACCGCCAGTTCTCGGTGACCATCGCCGCGGCGATGCTG
CTGTCGCTGCTGGTGGCGCTGACCTTGAGCCCGGCGTTGTGCGCGAGCCTGCTTAGGCCGATCGCGCACGGCCAACAGGT
GTCGCGCAAGGGAGTGCTCGGGCGCTTCTTCGGTTGGTTCAACGTGCGCTTCGACCGCGGCGCCGATGGCTATGGTCGCG
GTGTGGGCAAGTTGATCGGCCATCGCAAACTCGGCGGGCTGGTCTATCTGGCGCTGCTCGTGGTAATGGCGCTGTTGTTC
TGGCGCCTGCCCAGTTCGTTCCTCCCCGACGAAGACCAGGGCATGTTGATGGTGATGTTCACCACGCCGGCCGGCGCCAC
CCAGCAGCGCACGCAGCAGTCGATCGACCAGGCCACCAGCTTCATCCTCAAGCAACCGGAGGTGGCGGGGATGATGACCA
TCTCCGGCTTCAGCTTTGCCGGCAGCAGCCAGAACTCGGGCATGGGTTTCATCAAGCTCAAGGATTGGGCGCAGCGCGAT
GCGCCCGCGCAGGAGATCGCCAACCGCATCACCGGCGCGATGATGGGCACGCTGCCCGATGCGCAGGTGTTCGCATTGTC
GCCGCCGGCGATCAACGGCCTGGGCAGCAGTTCCGGCTTCACCCTGGAGCTGCAGGACGTGGCCGGCAAGGGCCACGACG
CGCTGGTCGCCGCGCGCCAGCAGCTGCTGCAGCTGGCCAGCGCCGACAAGGATCTGACCGCGGTGCGCTTCAACGGCCTG
GAAGACGCGCCGACCTACCGCGTGCAGATCGACGACGCCAAGGCCGGCGCGCTCGGCCTGGATGCGTCTGACATCAACAC
CACGCTGGCCACGGTGATGGGCGGCAGCTACGTCAACGACTTCCTCAACAACAACCGGGTCAAGCGCGTCTACGTGCAGG
GCGAGGCGCGCGCGCGCATGCTGCCCGCCGACATCGGCTGCTGGTACGTGCGCAACAGCAGCTCGGAGATGGTGCCGTTC
TCTGCCTTCTCCAGCAGCGCATGGGCGTATGCGCCGCAGGTGCTGAGCCGCTTCAACGGCGTGGAGTCGATGGAGATCAC
CGGCAGCGCCGCCACTGGCATCAGTTCCGGCGAGGCGATGAACGGCATCGCCGCGCTGGTGGGCAAGCTCGGCAAGGACG
TGAGCTACGCCTGGTCGGGCATGTCCTACCAGGAGCAGGCCGCCGGCGCGCAGACCTGGATGCTGTACGCGGTGTCGCTG
GTGTTCGTGTTCCTGTGCCTGGCCGCCCTTTACGAGAGTTGGTCGATCCCGATCTCGGTGATGCTGGCGGTGCCGGTGGG
CATCGTCGGCGCGCTGCTGGCAACATGGCTGCGCGGGCTCTCCAACGACATCTATTTCCAGGTCGGCCTGCTGGCGACGA
TGGGCCTGGCGGCCAAGAACGGCATCCTGATCGTGGAGTTCGCCAAGGAACTGGAAGAGAAGGGCCAGCCGCTGATCGAA
GCGACCTTGCATGCCGCGCGCATGCGCTTGCGCCCGATCGTGATGACCTCGCTGGCGTTCCTGCTCGGCGTGCTGCCGAT
GGTGGTCAGCAGCGGCGCCGGCTCCGGTGGACGCCATTCGCTGGGTACCGGTGTGCTCGGCGGCACGCTGGTCTCTACGC
TGCTGGGCATCTTCTTCGTGCCGTTGTTCTACGTGATGGTGCGCAGCGTGTTTCCTGGTAGGGCGTCTGATCACGCGACA
GCCGCTGAGACGTCCGAGGTGGCCCCGTGA

Upstream 100 bases:

>100_bases
AGTGACCGCGGCCGCGATGGCCGGCAATGCCGCCGCCACCGCCCCGGCGGCCACGCAGGGCACCGCCGCGGCGGCGCCCA
AGGCCGACTGAGGAACCGCC

Downstream 100 bases:

>100_bases
TGCGCTACGGCTTTGCAAGTGTCGCAGTGGCCTGCGCCATCGCCTTGAGTGGCTGCGTCAGCATGGCGCCGCATTACGCA
CGCCCGGATGCGCCGGTGCC

Product: multidrug efflux transporter

Products: Proton [Cytoplasm]; multidrug [Periplasm] [C]

Alternate protein names: Multidrug-efflux transporter MexB [H]

Number of amino acids: Translated: 1049; Mature: 1048

Protein sequence:

>1049_residues
MARFFIDRPIFAWVIAIVITLAGALSILSLPLEQYPNIAPPTINVSATYTGASAQTVQNSVTQILEQQMTGLDHLLYMSS
SSSSAGTASITLTFESGTDPDTAQVQVQNKVSQGEAMLPEAVQSNGVTVTKSTGSSMFMVLAFTSEDGSMDSTDIGDYMV
STLQDPISRLNGVGGVNVFGSEYAMRVWLDPEKLRTYSLMPADVSNAISAQNADVSSGALGALPAVQGQQLNATVTSRSK
LKTPAQFEAIVLKSQPGGATVYLRDVARVELGSKSYASSSKYNGKSASGMGLELATGANALDAAKAVEAKLEQLKPYFPT
GLTYEVAYDTTPFVRISIEEVVKTLLEAIVLVVLVMYLFLQNWRATLVPVIAVPVVLLGTFGVLALLGYSINTLTMFAMV
LAIGLLVDDAIVVVENVERLMSEQGMSPRQATYTSMGQISGALVGIALVLTAVFLPMAFFGGATGEIYRQFSVTIAAAML
LSLLVALTLSPALCASLLRPIAHGQQVSRKGVLGRFFGWFNVRFDRGADGYGRGVGKLIGHRKLGGLVYLALLVVMALLF
WRLPSSFLPDEDQGMLMVMFTTPAGATQQRTQQSIDQATSFILKQPEVAGMMTISGFSFAGSSQNSGMGFIKLKDWAQRD
APAQEIANRITGAMMGTLPDAQVFALSPPAINGLGSSSGFTLELQDVAGKGHDALVAARQQLLQLASADKDLTAVRFNGL
EDAPTYRVQIDDAKAGALGLDASDINTTLATVMGGSYVNDFLNNNRVKRVYVQGEARARMLPADIGCWYVRNSSSEMVPF
SAFSSSAWAYAPQVLSRFNGVESMEITGSAATGISSGEAMNGIAALVGKLGKDVSYAWSGMSYQEQAAGAQTWMLYAVSL
VFVFLCLAALYESWSIPISVMLAVPVGIVGALLATWLRGLSNDIYFQVGLLATMGLAAKNGILIVEFAKELEEKGQPLIE
ATLHAARMRLRPIVMTSLAFLLGVLPMVVSSGAGSGGRHSLGTGVLGGTLVSTLLGIFFVPLFYVMVRSVFPGRASDHAT
AAETSEVAP

Sequences:

>Translated_1049_residues
MARFFIDRPIFAWVIAIVITLAGALSILSLPLEQYPNIAPPTINVSATYTGASAQTVQNSVTQILEQQMTGLDHLLYMSS
SSSSAGTASITLTFESGTDPDTAQVQVQNKVSQGEAMLPEAVQSNGVTVTKSTGSSMFMVLAFTSEDGSMDSTDIGDYMV
STLQDPISRLNGVGGVNVFGSEYAMRVWLDPEKLRTYSLMPADVSNAISAQNADVSSGALGALPAVQGQQLNATVTSRSK
LKTPAQFEAIVLKSQPGGATVYLRDVARVELGSKSYASSSKYNGKSASGMGLELATGANALDAAKAVEAKLEQLKPYFPT
GLTYEVAYDTTPFVRISIEEVVKTLLEAIVLVVLVMYLFLQNWRATLVPVIAVPVVLLGTFGVLALLGYSINTLTMFAMV
LAIGLLVDDAIVVVENVERLMSEQGMSPRQATYTSMGQISGALVGIALVLTAVFLPMAFFGGATGEIYRQFSVTIAAAML
LSLLVALTLSPALCASLLRPIAHGQQVSRKGVLGRFFGWFNVRFDRGADGYGRGVGKLIGHRKLGGLVYLALLVVMALLF
WRLPSSFLPDEDQGMLMVMFTTPAGATQQRTQQSIDQATSFILKQPEVAGMMTISGFSFAGSSQNSGMGFIKLKDWAQRD
APAQEIANRITGAMMGTLPDAQVFALSPPAINGLGSSSGFTLELQDVAGKGHDALVAARQQLLQLASADKDLTAVRFNGL
EDAPTYRVQIDDAKAGALGLDASDINTTLATVMGGSYVNDFLNNNRVKRVYVQGEARARMLPADIGCWYVRNSSSEMVPF
SAFSSSAWAYAPQVLSRFNGVESMEITGSAATGISSGEAMNGIAALVGKLGKDVSYAWSGMSYQEQAAGAQTWMLYAVSL
VFVFLCLAALYESWSIPISVMLAVPVGIVGALLATWLRGLSNDIYFQVGLLATMGLAAKNGILIVEFAKELEEKGQPLIE
ATLHAARMRLRPIVMTSLAFLLGVLPMVVSSGAGSGGRHSLGTGVLGGTLVSTLLGIFFVPLFYVMVRSVFPGRASDHAT
AAETSEVAP
>Mature_1048_residues
ARFFIDRPIFAWVIAIVITLAGALSILSLPLEQYPNIAPPTINVSATYTGASAQTVQNSVTQILEQQMTGLDHLLYMSSS
SSSAGTASITLTFESGTDPDTAQVQVQNKVSQGEAMLPEAVQSNGVTVTKSTGSSMFMVLAFTSEDGSMDSTDIGDYMVS
TLQDPISRLNGVGGVNVFGSEYAMRVWLDPEKLRTYSLMPADVSNAISAQNADVSSGALGALPAVQGQQLNATVTSRSKL
KTPAQFEAIVLKSQPGGATVYLRDVARVELGSKSYASSSKYNGKSASGMGLELATGANALDAAKAVEAKLEQLKPYFPTG
LTYEVAYDTTPFVRISIEEVVKTLLEAIVLVVLVMYLFLQNWRATLVPVIAVPVVLLGTFGVLALLGYSINTLTMFAMVL
AIGLLVDDAIVVVENVERLMSEQGMSPRQATYTSMGQISGALVGIALVLTAVFLPMAFFGGATGEIYRQFSVTIAAAMLL
SLLVALTLSPALCASLLRPIAHGQQVSRKGVLGRFFGWFNVRFDRGADGYGRGVGKLIGHRKLGGLVYLALLVVMALLFW
RLPSSFLPDEDQGMLMVMFTTPAGATQQRTQQSIDQATSFILKQPEVAGMMTISGFSFAGSSQNSGMGFIKLKDWAQRDA
PAQEIANRITGAMMGTLPDAQVFALSPPAINGLGSSSGFTLELQDVAGKGHDALVAARQQLLQLASADKDLTAVRFNGLE
DAPTYRVQIDDAKAGALGLDASDINTTLATVMGGSYVNDFLNNNRVKRVYVQGEARARMLPADIGCWYVRNSSSEMVPFS
AFSSSAWAYAPQVLSRFNGVESMEITGSAATGISSGEAMNGIAALVGKLGKDVSYAWSGMSYQEQAAGAQTWMLYAVSLV
FVFLCLAALYESWSIPISVMLAVPVGIVGALLATWLRGLSNDIYFQVGLLATMGLAAKNGILIVEFAKELEEKGQPLIEA
TLHAARMRLRPIVMTSLAFLLGVLPMVVSSGAGSGGRHSLGTGVLGGTLVSTLLGIFFVPLFYVMVRSVFPGRASDHATA
AETSEVAP

Specific function: The ability to export antibiotics and solvents is dramatically decreased in the presence of the proton conductor carbonyl cyanide m-chlorophenylhydrazone (CCCP), showing that an energized inner membrane is required for efflux. It is thought that the MexB

COG id: COG0841

COG function: function code V; Cation/multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AcrB/AcrD/AcrF (TC 2.A.6) family [H]

Homologues:

Organism=Escherichia coli, GI1788814, Length=1038, Percent_Identity=57.8034682080925, Blast_Score=1216, Evalue=0.0,
Organism=Escherichia coli, GI1786667, Length=1027, Percent_Identity=58.6173320350536, Blast_Score=1198, Evalue=0.0,
Organism=Escherichia coli, GI1789666, Length=1039, Percent_Identity=56.5928777670837, Blast_Score=1171, Evalue=0.0,
Organism=Escherichia coli, GI1789930, Length=1024, Percent_Identity=55.37109375, Blast_Score=1121, Evalue=0.0,
Organism=Escherichia coli, GI1788390, Length=1038, Percent_Identity=30.5394990366089, Blast_Score=399, Evalue=1e-112,
Organism=Escherichia coli, GI1788391, Length=1035, Percent_Identity=30.6280193236715, Blast_Score=390, Evalue=1e-109,
Organism=Escherichia coli, GI1786788, Length=1071, Percent_Identity=23.9028944911298, Blast_Score=225, Evalue=1e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR004764 [H]

Pfam domain/function: PF00873 ACR_tran [H]

EC number: NA

Molecular weight: Translated: 111198; Mature: 111067

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50156 SSD ; PS01159 WW_DOMAIN_1 ; PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFFIDRPIFAWVIAIVITLAGALSILSLPLEQYPNIAPPTINVSATYTGASAQTVQNS
CCCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEEECCCHHHHHHHH
VTQILEQQMTGLDHLLYMSSSSSSAGTASITLTFESGTDPDTAQVQVQNKVSQGEAMLPE
HHHHHHHHHCCHHHEEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEHHHHCCCCHHCHH
AVQSNGVTVTKSTGSSMFMVLAFTSEDGSMDSTDIGDYMVSTLQDPISRLNGVGGVNVFG
HHHCCCEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEC
SEYAMRVWLDPEKLRTYSLMPADVSNAISAQNADVSSGALGALPAVQGQQLNATVTSRSK
CCEEEEEEECHHHHHEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCHHH
LKTPAQFEAIVLKSQPGGATVYLRDVARVELGSKSYASSSKYNGKSASGMGLELATGANA
CCCCCCEEEEEEECCCCCCEEEEEEHHHHHCCCCHHCCCCCCCCCCCCCCCEEEECCCCH
LDAAKAVEAKLEQLKPYFPTGLTYEVAYDTTPFVRISIEEVVKTLLEAIVLVVLVMYLFL
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QNWRATLVPVIAVPVVLLGTFGVLALLGYSINTLTMFAMVLAIGLLVDDAIVVVENVERL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSEQGMSPRQATYTSMGQISGALVGIALVLTAVFLPMAFFGGATGEIYRQFSVTIAAAML
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSLLVALTLSPALCASLLRPIAHGQQVSRKGVLGRFFGWFNVRFDRGADGYGRGVGKLIG
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHEEEEEECCCCCCCCCHHHHHHH
HRKLGGLVYLALLVVMALLFWRLPSSFLPDEDQGMLMVMFTTPAGATQQRTQQSIDQATS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
FILKQPEVAGMMTISGFSFAGSSQNSGMGFIKLKDWAQRDAPAQEIANRITGAMMGTLPD
HHHCCCCCCCEEEECCCEECCCCCCCCEEEEEECCHHCCCCCHHHHHHHHHHHHHCCCCC
AQVFALSPPAINGLGSSSGFTLELQDVAGKGHDALVAARQQLLQLASADKDLTAVRFNGL
CEEEEECCCCCCCCCCCCCCEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
EDAPTYRVQIDDAKAGALGLDASDINTTLATVMGGSYVNDFLNNNRVKRVYVQGEARARM
CCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCCCEE
LPADIGCWYVRNSSSEMVPFSAFSSSAWAYAPQVLSRFNGVESMEITGSAATGISSGEAM
CCCCCCEEEEECCCCCCCEEHHCCCCCHHHHHHHHHHHCCCCCEEECCCHHCCCCCCHHH
NGIAALVGKLGKDVSYAWSGMSYQEQAAGAQTWMLYAVSLVFVFLCLAALYESWSIPISV
HHHHHHHHHHCCCHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
MLAVPVGIVGALLATWLRGLSNDIYFQVGLLATMGLAAKNGILIVEFAKELEEKGQPLIE
HHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCHHHH
ATLHAARMRLRPIVMTSLAFLLGVLPMVVSSGAGSGGRHSLGTGVLGGTLVSTLLGIFFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PLFYVMVRSVFPGRASDHATAAETSEVAP
HHHHHHHHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ARFFIDRPIFAWVIAIVITLAGALSILSLPLEQYPNIAPPTINVSATYTGASAQTVQNS
CCEEECCHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCCCEEEEEEEECCCHHHHHHHH
VTQILEQQMTGLDHLLYMSSSSSSAGTASITLTFESGTDPDTAQVQVQNKVSQGEAMLPE
HHHHHHHHHCCHHHEEEEECCCCCCCEEEEEEEECCCCCCCCEEEEEHHHHCCCCHHCHH
AVQSNGVTVTKSTGSSMFMVLAFTSEDGSMDSTDIGDYMVSTLQDPISRLNGVGGVNVFG
HHHCCCEEEEECCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEC
SEYAMRVWLDPEKLRTYSLMPADVSNAISAQNADVSSGALGALPAVQGQQLNATVTSRSK
CCEEEEEEECHHHHHEEECCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEECCHHH
LKTPAQFEAIVLKSQPGGATVYLRDVARVELGSKSYASSSKYNGKSASGMGLELATGANA
CCCCCCEEEEEEECCCCCCEEEEEEHHHHHCCCCHHCCCCCCCCCCCCCCCEEEECCCCH
LDAAKAVEAKLEQLKPYFPTGLTYEVAYDTTPFVRISIEEVVKTLLEAIVLVVLVMYLFL
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
QNWRATLVPVIAVPVVLLGTFGVLALLGYSINTLTMFAMVLAIGLLVDDAIVVVENVERL
HCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MSEQGMSPRQATYTSMGQISGALVGIALVLTAVFLPMAFFGGATGEIYRQFSVTIAAAML
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LSLLVALTLSPALCASLLRPIAHGQQVSRKGVLGRFFGWFNVRFDRGADGYGRGVGKLIG
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCHHHHHHHEEEEEECCCCCCCCCHHHHHHH
HRKLGGLVYLALLVVMALLFWRLPSSFLPDEDQGMLMVMFTTPAGATQQRTQQSIDQATS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHH
FILKQPEVAGMMTISGFSFAGSSQNSGMGFIKLKDWAQRDAPAQEIANRITGAMMGTLPD
HHHCCCCCCCEEEECCCEECCCCCCCCEEEEEECCHHCCCCCHHHHHHHHHHHHHCCCCC
AQVFALSPPAINGLGSSSGFTLELQDVAGKGHDALVAARQQLLQLASADKDLTAVRFNGL
CEEEEECCCCCCCCCCCCCCEEEEHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECCC
EDAPTYRVQIDDAKAGALGLDASDINTTLATVMGGSYVNDFLNNNRVKRVYVQGEARARM
CCCCEEEEEECCCCCCEECCCHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEEECCCCCEE
LPADIGCWYVRNSSSEMVPFSAFSSSAWAYAPQVLSRFNGVESMEITGSAATGISSGEAM
CCCCCCEEEEECCCCCCCEEHHCCCCCHHHHHHHHHHHCCCCCEEECCCHHCCCCCCHHH
NGIAALVGKLGKDVSYAWSGMSYQEQAAGAQTWMLYAVSLVFVFLCLAALYESWSIPISV
HHHHHHHHHHCCCHHHHCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
MLAVPVGIVGALLATWLRGLSNDIYFQVGLLATMGLAAKNGILIVEFAKELEEKGQPLIE
HHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHCCCCEEEEHHHHHHHHCCCHHHH
ATLHAARMRLRPIVMTSLAFLLGVLPMVVSSGAGSGGRHSLGTGVLGGTLVSTLLGIFFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
PLFYVMVRSVFPGRASDHATAAETSEVAP
HHHHHHHHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; multidrug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + multidrug [Cytoplasm] = Proton [Cytoplasm] + multidrug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7968531; 10984043; 9989496; 8226684; 8540696; 9603892; 10187844 [H]