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The map label for this gene is mttC [H]

Identifier: 21241087

GI number: 21241087

Start: 374409

End: 375221

Strand: Direct

Name: mttC [H]

Synonym: XAC0313

Alternate gene names: 21241087

Gene position: 374409-375221 (Clockwise)

Preceding gene: 21241086

Following gene: 21241089

Centisome position: 7.23

GC content: 65.68

Gene sequence:

>813_bases
ATGCAATTGATCGATATCGGCGCCAACCTCACCCACGACTCGTTCGACCGCGATCGCGATGCGGTGCTGCAACGCGCACG
CGATGCCGGCGTGGCGCAGCTGGTGATTACCGGCGCCAGCCGCGAGCATTCGCCGCTGGCCTTGCAACTGGCGCAGCAAC
ACCCCGGATTCCTGTACGCCACCGCTGGCGTGCACCCGCATCACGCGGTGGAATTCACTGCCGAATGCGAAGCGGAAATG
CGCACCCTGCAGGCGCATCCGCAGGTGGTGGCAGTGGGCGAGTGTGGGCTGGATTACTTCCGCGATTTTGCGCCGCGCCC
TGCGCAGCGCAAGGCCTTCGAACGCCAGCTGCAGTTGGCGGCCGACAACGGCAAGCCGCTGTTCCTGCACCAGCGCGATG
CGCACGAGGATTTCATCGCCATCATGCGCAGCTTCGAGGGGCGCCTGGGTGCGGCGGTGGTGCATTGCTTCACCGGCACG
CGCGACGAACTGTTCGCGTATCTGGACCGCGATTACTACATCGGCATCACCGGCTGGCTCTGCGATGAGCGCCGCGGTGC
GCATCTGCGCGAGCTGGTGCGCAACATTCCGGCCAACCGTTTGATGATCGAAACCGATGCGCCGTACCTGCTGCCGCGCA
CGCTCAAGCCGATGCCCAAGGATCGTCGCAACGAGCCGATGTTCCTGTCGCATATCGTCGAAGAGCTGGCGCGCGATCGT
GGCGAGGATGTCGCGGTGACCGCCGCCAACAGCACGGCCGCGGCGCGTGCGTTCTTCCGCTTGTCGGCGCCTGCCAGCAC
CACGAGCGGCTAA

Upstream 100 bases:

>100_bases
TGCACGCCACCTCTCCCGCCAGCGGGAGAAGGGAGGCTCAGCGGAGCTAACCCTCGCTCGTTACACTTACGCGGCTCACC
CCCCACACGACACCCGCAGC

Downstream 100 bases:

>100_bases
CACCATGTCGCAATCGTGGACACCACGGTGCGCGGATACCGCACTGCATGCGTGCCGCATGCCGCACCGAGCCGGTCGCA
TTGACCGGCGGTGAGCGCCG

Product: type V secretory pathway protein

Products: NA

Alternate protein names: DNase tatD [H]

Number of amino acids: Translated: 270; Mature: 270

Protein sequence:

>270_residues
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVAQLVITGASREHSPLALQLAQQHPGFLYATAGVHPHHAVEFTAECEAEM
RTLQAHPQVVAVGECGLDYFRDFAPRPAQRKAFERQLQLAADNGKPLFLHQRDAHEDFIAIMRSFEGRLGAAVVHCFTGT
RDELFAYLDRDYYIGITGWLCDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
GEDVAVTAANSTAAARAFFRLSAPASTTSG

Sequences:

>Translated_270_residues
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVAQLVITGASREHSPLALQLAQQHPGFLYATAGVHPHHAVEFTAECEAEM
RTLQAHPQVVAVGECGLDYFRDFAPRPAQRKAFERQLQLAADNGKPLFLHQRDAHEDFIAIMRSFEGRLGAAVVHCFTGT
RDELFAYLDRDYYIGITGWLCDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
GEDVAVTAANSTAAARAFFRLSAPASTTSG
>Mature_270_residues
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVAQLVITGASREHSPLALQLAQQHPGFLYATAGVHPHHAVEFTAECEAEM
RTLQAHPQVVAVGECGLDYFRDFAPRPAQRKAFERQLQLAADNGKPLFLHQRDAHEDFIAIMRSFEGRLGAAVVHCFTGT
RDELFAYLDRDYYIGITGWLCDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
GEDVAVTAANSTAAARAFFRLSAPASTTSG

Specific function: Shows DNase activity [H]

COG id: COG0084

COG function: function code L; Mg-dependent DNase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tatD DNase family [H]

Homologues:

Organism=Homo sapiens, GI14042943, Length=297, Percent_Identity=35.6902356902357, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI225903439, Length=253, Percent_Identity=36.3636363636364, Blast_Score=133, Evalue=1e-31,
Organism=Homo sapiens, GI225903424, Length=197, Percent_Identity=37.0558375634518, Blast_Score=115, Evalue=3e-26,
Organism=Homo sapiens, GI110349730, Length=269, Percent_Identity=27.1375464684015, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI110349734, Length=269, Percent_Identity=27.5092936802974, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI226061853, Length=275, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI226061614, Length=261, Percent_Identity=27.2030651340996, Blast_Score=75, Evalue=7e-14,
Organism=Homo sapiens, GI226061595, Length=228, Percent_Identity=27.1929824561404, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI48994985, Length=260, Percent_Identity=50, Blast_Score=259, Evalue=1e-70,
Organism=Escherichia coli, GI1787342, Length=268, Percent_Identity=29.8507462686567, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082439, Length=254, Percent_Identity=29.5275590551181, Blast_Score=92, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17559024, Length=281, Percent_Identity=39.1459074733096, Blast_Score=213, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI71980746, Length=269, Percent_Identity=26.3940520446097, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17565396, Length=172, Percent_Identity=32.5581395348837, Blast_Score=77, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24648690, Length=274, Percent_Identity=37.5912408759124, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI221330018, Length=280, Percent_Identity=35, Blast_Score=127, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24586117, Length=253, Percent_Identity=34.7826086956522, Blast_Score=117, Evalue=8e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015992
- InterPro:   IPR001130
- InterPro:   IPR018228
- InterPro:   IPR012278 [H]

Pfam domain/function: PF01026 TatD_DNase [H]

EC number: 3.1.21.-

Molecular weight: Translated: 30170; Mature: 30170

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS01090 TATD_2 ; PS01091 TATD_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVAQLVITGASREHSPLALQLAQQHPGFLYA
CEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEHHCCCCEEEE
TAGVHPHHAVEFTAECEAEMRTLQAHPQVVAVGECGLDYFRDFAPRPAQRKAFERQLQLA
ECCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHC
ADNGKPLFLHQRDAHEDFIAIMRSFEGRLGAAVVHCFTGTRDELFAYLDRDYYIGITGWL
CCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHEECCCCHHHHHHHHCCCEEEEEEEEE
CDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
CCCCCCHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GEDVAVTAANSTAAARAFFRLSAPASTTSG
CCCEEEEECCCHHHHHHHEEEECCCCCCCC
>Mature Secondary Structure
MQLIDIGANLTHDSFDRDRDAVLQRARDAGVAQLVITGASREHSPLALQLAQQHPGFLYA
CEEEECCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEEHHCCCCEEEE
TAGVHPHHAVEFTAECEAEMRTLQAHPQVVAVGECGLDYFRDFAPRPAQRKAFERQLQLA
ECCCCCCCEEEEHHHHHHHHHHHHCCCCEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHC
ADNGKPLFLHQRDAHEDFIAIMRSFEGRLGAAVVHCFTGTRDELFAYLDRDYYIGITGWL
CCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHEECCCCHHHHHHHHCCCEEEEEEEEE
CDERRGAHLRELVRNIPANRLMIETDAPYLLPRTLKPMPKDRRNEPMFLSHIVEELARDR
CCCCCCHHHHHHHHHCCCCEEEEECCCCEECCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
GEDVAVTAANSTAAARAFFRLSAPASTTSG
CCCEEEEECCCHHHHHHHEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Mg [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1584020; 9649434; 1379743; 9278503; 10747959 [H]