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The map label for this gene is fabH [H]

Identifier: 21241007

GI number: 21241007

Start: 280846

End: 281862

Strand: Direct

Name: fabH [H]

Synonym: XAC0233

Alternate gene names: 21241007

Gene position: 280846-281862 (Clockwise)

Preceding gene: 21241006

Following gene: 21241008

Centisome position: 5.43

GC content: 64.6

Gene sequence:

>1017_bases
ATGCTCTTCCAGAATGTCTCCATCGCGGGACTGGCGCATGTTGATGCGCCGCACACGCTGACTTCCAAGGAAATCAACGA
ACGCCTGCAACCGACCTACGACCGCCTCGGGATCAAGACCGACGTGTTGGGCGACGTTGCCGGTATCCATGCACGGCGCT
TGTGGGACCAGGATGTCCAGGCCTCGGACGCCGCCACCCAGGCCGCGCGCAAGGCGCTGATCGACGCCGGTATCGGCATC
GAGAAGATCGGCCTGCTGGTCAACACCTCGGTGAGTCGCGACTACCTGGAGCCGTCCACGGCGTCCATCGTGTCCGGCAA
CCTGGGCGTGGGCGACCACTGCGTTACCTTCGACGTGGCCAACGCCTGCCTCGCCTTCATCAATGGCATGGACATCGCCG
CGCGCATGCTCGAGCGCGGCGAGATCGACTACGCCTTGGTCGTGGATGGCGAAACTGCCAACCTGGTGTACGAAAAGACC
CTCGAGCGCATGACCTCGCCGGACGTCACCGAGGAGGAGTTCCGCAACGAACTTGCCGCGCTGACCCTGGGGTGCGGTGC
AGCAGCCATGGTCATGGCGCGTACCGAGCTGGTGCCCGACGCCCCGCGCTACAAGGGCGGCGTGACCCGCTCGGCCACCG
AGTGGAACAAGCTATGCCGGGGCAACCTGGACCGCATGGTCACCGATACCCGCTTGCTGTTGATCGAAGGCATCAAGTTG
GCCCAGAAGACCTTCATGGCCGCGCGCCAGGTGCTGGGTTGGGCGGTGGACGAGCTGGACCAGTTCGTCATCCACCAGGT
CAGCCGCCCCCACACCGCCGCCTTCGTGAAGTCGTTCGGCATCGACCCGGCCAAGGTCATGACCATCTTCGGCGAGCACG
GAAACATCGGTCCGGCCTCGGTGCCGATCGTGTTGAGCAAGCTCAAGGAGCTGGGCCGCCTGAAGAAGGGCGACCGCATC
GCGCTGCTGGGCATCGGCTCGGGCTTGAATTGCTCGATGGCGGAAGTGGTTTGGTGA

Upstream 100 bases:

>100_bases
CCGTTGGGCTGGGGCGCAGGCGTTTCAAATGTAAAGATGCGGTAAAACCAGCCAGCGGCTAGACTAGCGCCCCCTCGCCT
GACGCCATGGCGCTACTTCG

Downstream 100 bases:

>100_bases
TGCGTGGTTGCACGGCATGCCTTGCTGCATGCCGTGCAACCTCGCCGCTTAAGAAAAAAAGTGCTATCTAAGTTTCCTTG
CAAGAACCATTGCTGCCTGT

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MLFQNVSIAGLAHVDAPHTLTSKEINERLQPTYDRLGIKTDVLGDVAGIHARRLWDQDVQASDAATQAARKALIDAGIGI
EKIGLLVNTSVSRDYLEPSTASIVSGNLGVGDHCVTFDVANACLAFINGMDIAARMLERGEIDYALVVDGETANLVYEKT
LERMTSPDVTEEEFRNELAALTLGCGAAAMVMARTELVPDAPRYKGGVTRSATEWNKLCRGNLDRMVTDTRLLLIEGIKL
AQKTFMAARQVLGWAVDELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGEHGNIGPASVPIVLSKLKELGRLKKGDRI
ALLGIGSGLNCSMAEVVW

Sequences:

>Translated_338_residues
MLFQNVSIAGLAHVDAPHTLTSKEINERLQPTYDRLGIKTDVLGDVAGIHARRLWDQDVQASDAATQAARKALIDAGIGI
EKIGLLVNTSVSRDYLEPSTASIVSGNLGVGDHCVTFDVANACLAFINGMDIAARMLERGEIDYALVVDGETANLVYEKT
LERMTSPDVTEEEFRNELAALTLGCGAAAMVMARTELVPDAPRYKGGVTRSATEWNKLCRGNLDRMVTDTRLLLIEGIKL
AQKTFMAARQVLGWAVDELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGEHGNIGPASVPIVLSKLKELGRLKKGDRI
ALLGIGSGLNCSMAEVVW
>Mature_338_residues
MLFQNVSIAGLAHVDAPHTLTSKEINERLQPTYDRLGIKTDVLGDVAGIHARRLWDQDVQASDAATQAARKALIDAGIGI
EKIGLLVNTSVSRDYLEPSTASIVSGNLGVGDHCVTFDVANACLAFINGMDIAARMLERGEIDYALVVDGETANLVYEKT
LERMTSPDVTEEEFRNELAALTLGCGAAAMVMARTELVPDAPRYKGGVTRSATEWNKLCRGNLDRMVTDTRLLLIEGIKL
AQKTFMAARQVLGWAVDELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGEHGNIGPASVPIVLSKLKELGRLKKGDRI
ALLGIGSGLNCSMAEVVW

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=295, Percent_Identity=27.4576271186441, Blast_Score=80, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 36543; Mature: 36543

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFQNVSIAGLAHVDAPHTLTSKEINERLQPTYDRLGIKTDVLGDVAGIHARRLWDQDVQ
CCCCCCCEEEEEECCCCCCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
ASDAATQAARKALIDAGIGIEKIGLLVNTSVSRDYLEPSTASIVSGNLGVGDHCVTFDVA
HHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCHHHCCCCCHHHEECCCCCCCCCHHHHHH
NACLAFINGMDIAARMLERGEIDYALVVDGETANLVYEKTLERMTSPDVTEEEFRNELAA
HHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LTLGCGAAAMVMARTELVPDAPRYKGGVTRSATEWNKLCRGNLDRMVTDTRLLLIEGIKL
HHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AQKTFMAARQVLGWAVDELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGEHGNIGPAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHEEECCCCCCCCHH
VPIVLSKLKELGRLKKGDRIALLGIGSGLNCSMAEVVW
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHCC
>Mature Secondary Structure
MLFQNVSIAGLAHVDAPHTLTSKEINERLQPTYDRLGIKTDVLGDVAGIHARRLWDQDVQ
CCCCCCCEEEEEECCCCCCCCHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
ASDAATQAARKALIDAGIGIEKIGLLVNTSVSRDYLEPSTASIVSGNLGVGDHCVTFDVA
HHHHHHHHHHHHHHHCCCCHHHHHEEEECCCCHHHCCCCCHHHEECCCCCCCCCHHHHHH
NACLAFINGMDIAARMLERGEIDYALVVDGETANLVYEKTLERMTSPDVTEEEFRNELAA
HHHHHHHCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LTLGCGAAAMVMARTELVPDAPRYKGGVTRSATEWNKLCRGNLDRMVTDTRLLLIEGIKL
HHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
AQKTFMAARQVLGWAVDELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGEHGNIGPAS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHEEECCCCCCCCHH
VPIVLSKLKELGRLKKGDRIALLGIGSGLNCSMAEVVW
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA