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The map label for this gene is fpoC [H]

Identifier: 21228591

GI number: 21228591

Start: 2967807

End: 2968283

Strand: Reverse

Name: fpoC [H]

Synonym: MM_2489

Alternate gene names: 21228591

Gene position: 2968283-2967807 (Counterclockwise)

Preceding gene: 21228592

Following gene: 21228590

Centisome position: 72.46

GC content: 48.01

Gene sequence:

>477_bases
ATGGACGCCAGAACGATTATAGAATCATTAACCGGGAAATTCCCGGAAGCGATTTCTGAAGCCGGGATCGAATCTCCAAT
CCGTATCCGGGCATATGTTGACAAAGATAAAGCAAAGGAGGTCTGCGAGTACCTTAAGGGCTCCCTTCAGTTCGACCACC
TCTGTTCCGTGAGCGGAGTGGACTATCCTCAGAGGGACGAACTCGAAGCAGTGTATCATATAGCTTCATATGACCACCCC
GTAGTCCTTATGCTGAAAGCAAGACTGCCAAGGGATTCTCCGGAAATAGAATCCGTTGTGTCTGTATACTGGAATGCAAA
CTGGTATGAAAGGGAGACCTACGAACTCTACGGGATATTCTTTAAGAATCATCCGGAACTGAAGCCTCTTGTTCTCCCTG
ATGACATGCTGGGTGAGTGGCCTCTCAGAAAAGACTATGAGGGTTTTCCGAACAGGACAGCAAGAAACCTGGTGTGA

Upstream 100 bases:

>100_bases
CCCTGATCCAGGGGTTTGTGGAACTGCAGGAAAAAATAAAAGCCAGAAAGGACCGGGGAACGGAATACTGAGGAGATTAA
GGCTTATTTGAGGGAATATA

Downstream 100 bases:

>100_bases
GGGGTGAAAAATGGAAGAAATGCTTGAATCAAATGAAATGATCGTACACCTGGGCCCTCAGCATCCCATGCAGCCCGGAC
CATTCAGATTGAACCTGAAA

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MDARTIIESLTGKFPEAISEAGIESPIRIRAYVDKDKAKEVCEYLKGSLQFDHLCSVSGVDYPQRDELEAVYHIASYDHP
VVLMLKARLPRDSPEIESVVSVYWNANWYERETYELYGIFFKNHPELKPLVLPDDMLGEWPLRKDYEGFPNRTARNLV

Sequences:

>Translated_158_residues
MDARTIIESLTGKFPEAISEAGIESPIRIRAYVDKDKAKEVCEYLKGSLQFDHLCSVSGVDYPQRDELEAVYHIASYDHP
VVLMLKARLPRDSPEIESVVSVYWNANWYERETYELYGIFFKNHPELKPLVLPDDMLGEWPLRKDYEGFPNRTARNLV
>Mature_158_residues
MDARTIIESLTGKFPEAISEAGIESPIRIRAYVDKDKAKEVCEYLKGSLQFDHLCSVSGVDYPQRDELEAVYHIASYDHP
VVLMLKARLPRDSPEIESVVSVYWNANWYERETYELYGIFFKNHPELKPLVLPDDMLGEWPLRKDYEGFPNRTARNLV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=136, Percent_Identity=31.6176470588235, Blast_Score=70, Evalue=8e-13,
Organism=Escherichia coli, GI145693162, Length=151, Percent_Identity=30.4635761589404, Blast_Score=72, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990788, Length=109, Percent_Identity=36.697247706422, Blast_Score=72, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563621, Length=109, Percent_Identity=36.697247706422, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24656494, Length=109, Percent_Identity=35.7798165137615, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 18326; Mature: 18326

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00542 COMPLEX1_30K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDARTIIESLTGKFPEAISEAGIESPIRIRAYVDKDKAKEVCEYLKGSLQFDHLCSVSGV
CCHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHCCCCHHHHCCCCCC
DYPQRDELEAVYHIASYDHPVVLMLKARLPRDSPEIESVVSVYWNANWYERETYELYGIF
CCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEE
FKNHPELKPLVLPDDMLGEWPLRKDYEGFPNRTARNLV
ECCCCCCCCEECCHHHCCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MDARTIIESLTGKFPEAISEAGIESPIRIRAYVDKDKAKEVCEYLKGSLQFDHLCSVSGV
CCHHHHHHHHHCCCHHHHHHCCCCCCEEEEEEECHHHHHHHHHHHHCCCCHHHHCCCCCC
DYPQRDELEAVYHIASYDHPVVLMLKARLPRDSPEIESVVSVYWNANWYERETYELYGIF
CCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEEE
FKNHPELKPLVLPDDMLGEWPLRKDYEGFPNRTARNLV
ECCCCCCCCEECCHHHCCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA