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The map label for this gene is fpoL [H]

Identifier: 21228584

GI number: 21228584

Start: 2962365

End: 2964383

Strand: Reverse

Name: fpoL [H]

Synonym: MM_2482

Alternate gene names: 21228584

Gene position: 2964383-2962365 (Counterclockwise)

Preceding gene: 21228585

Following gene: 21228583

Centisome position: 72.37

GC content: 49.63

Gene sequence:

>2019_bases
GTGGTAAAAACGGCTCTGGAAGAATTTGCATTTTTAATCCCCCTGCTTCCGGCACTGGCTTTTGCGATCACCTTCTTCTT
TGGCAGAAAAATGCCATCTGGAGGGGCAATCGTTCCCATCCTTGCCATCGCCGCCTCCTTTGTAATCTCTTTTGCGATTA
CCCTCGGGCTGCTGGCAAATCCCGAAGAGGTTATAAGCCAGTCCTATTCCTGGTTTGCAGTACTTAACATAGGAATATTA
ATCGACCCCCTGGCTGCAGTCATGCTGTCAATGGTCTCCTTTGTGAGCCTGTTAATCCATATCTATGCAGTAAGTTACAT
GTCCCATGATGCAGGAAAAGCAAGGTACTTTGCAGAAACCGCACTTTTCACAGCGGCAATGCTTTCCCTGGTCCTTTCGG
ACAACATCCTGCAGCTCTTTGTTTCCTGGGAACTTGTCGGCCTCTGTTCCTACCTGCTTATAGGGTTCTGGTTCGAAAAA
CCGTCAGCAGCAGCAGCAGCCAAGAAAGCGTTCCTGACAACCAGGATCGGAGACGTTATGTTCCTTACAGGAATCATCGT
GCTCACTTCCGACCTCCTTAAGGTTTCAGGCGGGTTCCAGGACGGAGTTTACCTTCTTCGCTTCGATGAAATCTTCAGTT
ACATCCCCGAGCTTGCAGCTCTTCAGATAAACATCCTGGGCTTTGAAATAAGCCACCTTACTATTATCACCCTGCTCTTC
TTCGGAGGAGCCGTAGGAAAGTCCGGTCAGTTCCCACTCCATGTGTGGCTGCCCGATGCAATGGAAGGTCCGACAACGGT
CTCAGCCCTTATCCATGCAGCAACAATGGTTACTGCTGGTGTTTACCTGGTAGCGCGGACTTTCCCGATGTTCATTGCAG
CCCCCGATTCCCTTATGGTAGTTGCTTACTTCGGAGGCTTTACAGCCCTCTTTGCAGGCACAATGGGCATTGTGATGAAC
GACCTCAAGCGTGTGCTCGCGTTCTCAACCATCAGCCAGCTAGGATATATGATGCTGGGCCTGGGTCTGGGCACTGCAAT
AGGGCTTGAAGCTGTCGGAATATCACTTTTCCACCTGATTAACCACGCTTTCTTCAAAGCGCTTCTCTTCCTCTGTGCAG
GCAGTGTGATCCATGCAGTCGGCACCCAGGACATGAGGGAGCTAGGAGGCGTAGGAAAGGTAATGCCCATAACTGCTGCA
ACAATGACCATAGCAGCCCTTGCCCTTGCAGGCTTCGGTATTCCGGGAACCTCAATAGGGACAAGCGGTTTCATGTCAAA
GGACCCTATTATTGAAGCTGCATACCTTTTCGGAGAACACAGCAGCAACTGGATCCCCTATGTATTCTCAATTCTTGCAG
CTCTCCTGACGTCCATCTACATTTTCAGGCTGATCTTCATGACCTTTACAGGCAAGCCGAGAAGCAACTATCACGGGCAT
GAGTCCCCTGCTATAATGACCATTCCCCTGTCAATTCTGGCAATTTTTGCCCTCGCTTTTGGTGCGCTGACAAGAACCGG
CTTTATGGAATTCCTTGAAGAAACCTTTACCAACAGCTTTGTAAACCTGGATATAGGAGCCCTTGCCGGCATAGGCGAAA
ATGAACTTGTGGCGGCAGCAGGTCACGAGCCTCTCGCAGTCCTCTGGCCTCCGGTGATAGTCGCACTTGCAGGCTTTGCA
ATTGCTTTTGTGATATATTACCTGAGAGCATTCAGCCTTGGACCTCTGGCTTCCATGAAGAACCCGATTTACAGGCTTCT
CTACAACCGCTACTACCAGCACCAGATCTACACCGAATTCTTCTCAATCGGAATTGTCTACGGGATCATTGCTTTCCTGA
CACAGGTAGTTGATGTGATCATTGACAGCGTTGTGGAAGGAATCGGAATTGTCACGGTTTTTGTGGGTGAAGAGCTCCGG
AAGATCCAGACAGGGGTTGTCCAGACCTATGCAACCGCATTAATCGCTGGTGTGAGCCTGCTGATAATACTTGTTAAACT
GATAATGGAGGTACTCTGA

Upstream 100 bases:

>100_bases
TCGCCCTTGCAGCCGCTGAAGCTGCAGTAGGGTTTGCGATATTCATGGCGATCTACAGAATGCACGATAAAATCAACCTT
GATGAACTTAATATTCTGAG

Downstream 100 bases:

>100_bases
TGCTGCCGGTCGCATCGTTGTTGATTCTGGTGCCGCTGATTTTCGCAGTCGTGACCTTTTTCACAAAAACAAAACAACTG
GCTGCAGGGTTTGGCTTTCT

Product: F420H2 dehydrogenase subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MVKTALEEFAFLIPLLPALAFAITFFFGRKMPSGGAIVPILAIAASFVISFAITLGLLANPEEVISQSYSWFAVLNIGIL
IDPLAAVMLSMVSFVSLLIHIYAVSYMSHDAGKARYFAETALFTAAMLSLVLSDNILQLFVSWELVGLCSYLLIGFWFEK
PSAAAAAKKAFLTTRIGDVMFLTGIIVLTSDLLKVSGGFQDGVYLLRFDEIFSYIPELAALQINILGFEISHLTIITLLF
FGGAVGKSGQFPLHVWLPDAMEGPTTVSALIHAATMVTAGVYLVARTFPMFIAAPDSLMVVAYFGGFTALFAGTMGIVMN
DLKRVLAFSTISQLGYMMLGLGLGTAIGLEAVGISLFHLINHAFFKALLFLCAGSVIHAVGTQDMRELGGVGKVMPITAA
TMTIAALALAGFGIPGTSIGTSGFMSKDPIIEAAYLFGEHSSNWIPYVFSILAALLTSIYIFRLIFMTFTGKPRSNYHGH
ESPAIMTIPLSILAIFALAFGALTRTGFMEFLEETFTNSFVNLDIGALAGIGENELVAAAGHEPLAVLWPPVIVALAGFA
IAFVIYYLRAFSLGPLASMKNPIYRLLYNRYYQHQIYTEFFSIGIVYGIIAFLTQVVDVIIDSVVEGIGIVTVFVGEELR
KIQTGVVQTYATALIAGVSLLIILVKLIMEVL

Sequences:

>Translated_672_residues
MVKTALEEFAFLIPLLPALAFAITFFFGRKMPSGGAIVPILAIAASFVISFAITLGLLANPEEVISQSYSWFAVLNIGIL
IDPLAAVMLSMVSFVSLLIHIYAVSYMSHDAGKARYFAETALFTAAMLSLVLSDNILQLFVSWELVGLCSYLLIGFWFEK
PSAAAAAKKAFLTTRIGDVMFLTGIIVLTSDLLKVSGGFQDGVYLLRFDEIFSYIPELAALQINILGFEISHLTIITLLF
FGGAVGKSGQFPLHVWLPDAMEGPTTVSALIHAATMVTAGVYLVARTFPMFIAAPDSLMVVAYFGGFTALFAGTMGIVMN
DLKRVLAFSTISQLGYMMLGLGLGTAIGLEAVGISLFHLINHAFFKALLFLCAGSVIHAVGTQDMRELGGVGKVMPITAA
TMTIAALALAGFGIPGTSIGTSGFMSKDPIIEAAYLFGEHSSNWIPYVFSILAALLTSIYIFRLIFMTFTGKPRSNYHGH
ESPAIMTIPLSILAIFALAFGALTRTGFMEFLEETFTNSFVNLDIGALAGIGENELVAAAGHEPLAVLWPPVIVALAGFA
IAFVIYYLRAFSLGPLASMKNPIYRLLYNRYYQHQIYTEFFSIGIVYGIIAFLTQVVDVIIDSVVEGIGIVTVFVGEELR
KIQTGVVQTYATALIAGVSLLIILVKLIMEVL
>Mature_672_residues
MVKTALEEFAFLIPLLPALAFAITFFFGRKMPSGGAIVPILAIAASFVISFAITLGLLANPEEVISQSYSWFAVLNIGIL
IDPLAAVMLSMVSFVSLLIHIYAVSYMSHDAGKARYFAETALFTAAMLSLVLSDNILQLFVSWELVGLCSYLLIGFWFEK
PSAAAAAKKAFLTTRIGDVMFLTGIIVLTSDLLKVSGGFQDGVYLLRFDEIFSYIPELAALQINILGFEISHLTIITLLF
FGGAVGKSGQFPLHVWLPDAMEGPTTVSALIHAATMVTAGVYLVARTFPMFIAAPDSLMVVAYFGGFTALFAGTMGIVMN
DLKRVLAFSTISQLGYMMLGLGLGTAIGLEAVGISLFHLINHAFFKALLFLCAGSVIHAVGTQDMRELGGVGKVMPITAA
TMTIAALALAGFGIPGTSIGTSGFMSKDPIIEAAYLFGEHSSNWIPYVFSILAALLTSIYIFRLIFMTFTGKPRSNYHGH
ESPAIMTIPLSILAIFALAFGALTRTGFMEFLEETFTNSFVNLDIGALAGIGENELVAAAGHEPLAVLWPPVIVALAGFA
IAFVIYYLRAFSLGPLASMKNPIYRLLYNRYYQHQIYTEFFSIGIVYGIIAFLTQVVDVIIDSVVEGIGIVTVFVGEELR
KIQTGVVQTYATALIAGVSLLIILVKLIMEVL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=437, Percent_Identity=35.9267734553776, Blast_Score=242, Evalue=8e-64,
Organism=Escherichia coli, GI1788614, Length=497, Percent_Identity=41.2474849094567, Blast_Score=313, Evalue=3e-86,
Organism=Escherichia coli, GI1788829, Length=373, Percent_Identity=34.0482573726542, Blast_Score=165, Evalue=7e-42,
Organism=Escherichia coli, GI1788831, Length=360, Percent_Identity=29.4444444444444, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788827, Length=455, Percent_Identity=28.1318681318681, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI2367154, Length=431, Percent_Identity=25.5220417633411, Blast_Score=96, Evalue=1e-20,
Organism=Escherichia coli, GI1788613, Length=417, Percent_Identity=22.7817745803357, Blast_Score=90, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR002128
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01010 Oxidored_q1_C; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 72394; Mature: 72394

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKTALEEFAFLIPLLPALAFAITFFFGRKMPSGGAIVPILAIAASFVISFAITLGLLAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PEEVISQSYSWFAVLNIGILIDPLAAVMLSMVSFVSLLIHIYAVSYMSHDAGKARYFAET
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALFTAAMLSLVLSDNILQLFVSWELVGLCSYLLIGFWFEKPSAAAAAKKAFLTTRIGDVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FLTGIIVLTSDLLKVSGGFQDGVYLLRFDEIFSYIPELAALQINILGFEISHLTIITLLF
HHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHH
FGGAVGKSGQFPLHVWLPDAMEGPTTVSALIHAATMVTAGVYLVARTFPMFIAAPDSLMV
HCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEE
VAYFGGFTALFAGTMGIVMNDLKRVLAFSTISQLGYMMLGLGLGTAIGLEAVGISLFHLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NHAFFKALLFLCAGSVIHAVGTQDMRELGGVGKVMPITAATMTIAALALAGFGIPGTSIG
HHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
TSGFMSKDPIIEAAYLFGEHSSNWIPYVFSILAALLTSIYIFRLIFMTFTGKPRSNYHGH
CCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ESPAIMTIPLSILAIFALAFGALTRTGFMEFLEETFTNSFVNLDIGALAGIGENELVAAA
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHCCCCCCCEEEEC
GHEPLAVLWPPVIVALAGFAIAFVIYYLRAFSLGPLASMKNPIYRLLYNRYYQHQIYTEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FSIGIVYGIIAFLTQVVDVIIDSVVEGIGIVTVFVGEELRKIQTGVVQTYATALIAGVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIILVKLIMEVL
HHHHHHHHHHHC
>Mature Secondary Structure
MVKTALEEFAFLIPLLPALAFAITFFFGRKMPSGGAIVPILAIAASFVISFAITLGLLAN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
PEEVISQSYSWFAVLNIGILIDPLAAVMLSMVSFVSLLIHIYAVSYMSHDAGKARYFAET
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
ALFTAAMLSLVLSDNILQLFVSWELVGLCSYLLIGFWFEKPSAAAAAKKAFLTTRIGDVM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
FLTGIIVLTSDLLKVSGGFQDGVYLLRFDEIFSYIPELAALQINILGFEISHLTIITLLF
HHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHEEEEEEEEHHHHHHHHHHH
FGGAVGKSGQFPLHVWLPDAMEGPTTVSALIHAATMVTAGVYLVARTFPMFIAAPDSLMV
HCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEE
VAYFGGFTALFAGTMGIVMNDLKRVLAFSTISQLGYMMLGLGLGTAIGLEAVGISLFHLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NHAFFKALLFLCAGSVIHAVGTQDMRELGGVGKVMPITAATMTIAALALAGFGIPGTSIG
HHHHHHHHHHHHHHHHHHHHCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCC
TSGFMSKDPIIEAAYLFGEHSSNWIPYVFSILAALLTSIYIFRLIFMTFTGKPRSNYHGH
CCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ESPAIMTIPLSILAIFALAFGALTRTGFMEFLEETFTNSFVNLDIGALAGIGENELVAAA
CCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECHHHHCCCCCCCEEEEC
GHEPLAVLWPPVIVALAGFAIAFVIYYLRAFSLGPLASMKNPIYRLLYNRYYQHQIYTEF
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
FSIGIVYGIIAFLTQVVDVIIDSVVEGIGIVTVFVGEELRKIQTGVVQTYATALIAGVSL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LIILVKLIMEVL
HHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]