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The map label for this gene is fpoN [H]

Identifier: 21228582

GI number: 21228582

Start: 2959393

End: 2960874

Strand: Reverse

Name: fpoN [H]

Synonym: MM_2480

Alternate gene names: 21228582

Gene position: 2960874-2959393 (Counterclockwise)

Preceding gene: 21228583

Following gene: 21228581

Centisome position: 72.28

GC content: 51.55

Gene sequence:

>1482_bases
ATGCAGGAAATAATGTACCTCGCACCTGAACTTGTTCTGGTTGCAACCGGACTGGTCATACTTCTGACCGGAGTTTTCCT
GTCCCCCCAGTCCAAGAATATACTGGGCTACCTGGCAACCCTGGGAACCCTTGCAGCCATCTTTCTGACGGTTAAAAGCT
TCGGGCTTCTGACAATGGAGGGTTTCAGCGTTCAGTATACAATATTCTCAGAAACCCTGAGTATCGACGCCCTTTCCCAG
TTCTTCAAACTGGTCTTCCTGGCAGTTGCCCTGATAGTCTCGATTGCCTCGATAAAGTATACAGAAAACAGCGACCACAC
AGAAGAGTTCTACACCCTGGTGCTCTTTGCGACCTTCGGGATGATGATTGTAGCCTCTGCAAACGACCTGATCCTGCTCT
TCTGTGCCTTTGAGCTGGCGAGTCTTGCGACCTTCGCCCTTGCAGGCTTTGAGAAACAGAATGCAAGGTCCCTTGAAGGA
GCCATGAAGTACTTTGTAATAGGCTCGGTTTCCGCAGCACTCATGCTCTTCGGGCTTTCCTTTGTTTACGGGGCAACCGG
CACAACAAGCATTCCCCTGATCGCTCAAAACCCGGGTCTTCTCACAGGAAATCCCATAGGCATTGTAGCAATTGTGCTCC
TGACTGCGGGTTTCGGCTTCAAGATGGCTCTTGTCCCCTTCCACATGTGGGCTCCGGACACATACCAGGGATCGCCTTCA
GTTGTTTCCGCCCTGCTCGCAGCCGGGTCAAAGAAAATGGGGTTTGTCGCAGCCTTCAGGGTATTCATCATAGCCCTTGC
AGCCCTTCAGCCTGACTGGCAGTTTATGTTTACCCTTCTGGCAGTGGTGACCATGACATTTGGAAACGTGGTCGCAGTTG
CCCAGACCAGCGTTAAACGCATGCTTGCCTACTCTTCCCTTGCACAGGCAGGATACATTGCAATGGCTTTTGCTGTAATG
ACACCCGTAGCTCTCGCAGGCGGCATAATGTATACCCTTGCCCATGCCTTTATGAAAGCAGGAGCATTTATTGCAGCCGC
AGCCGTTGTCTGGATGATAACTTCGGAAAAGACAGGAAACCTCGACATCCCTGACCACCTGGACAGCTTCAGGGGTCTTG
GAAAGAGAATGCCTCTTGCAGCTCTCTGTATGACGGTTTTCGTCTTTGCACTTGCAGGAATCCCCCCGACTGCAGGTTTC
ATGGCAAAGTTCGTGCTCTTCTCTTCAACCATTCAGGCGGGCATGACCTGGCTTGCAGTAATCGCCATCCTGAACAGTGC
CCTTTCACTGTTCTACTACGCACGGCTTGTGAAATACATGTACTTCATGCCCCCTGAGGGTAAAACGGAAAAGGTCAGCA
TCCCGTTCCCATACGCAGCAGCTCTTCTGGTTGCAGTTGCAGGCGTGCTGGTAATGGGTCTCTGGCCTGAACCCTTCGTG
GAACTGGCTATGAAAGCAGCAATGGTACTTGTGCCATTCTAA

Upstream 100 bases:

>100_bases
TGTGCTTTACTTCGGCCTGAACCCAAGCCCGGTGCTTGATATGATGATTAATAATTCGGAAGCAATAGTCAGCCTTGCGG
CTGGCATGGGGGTGTGAGAA

Downstream 100 bases:

>100_bases
GGAGGTATTAGAAATGACAGATTGCGACCTGTGTGGAAAAGGAATCCCGACCGTTATCCCGGTCAGGACTTACCCTCCTC
TCCTGAGATTCGCCTACCCC

Product: F420H2 dehydrogenase subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MQEIMYLAPELVLVATGLVILLTGVFLSPQSKNILGYLATLGTLAAIFLTVKSFGLLTMEGFSVQYTIFSETLSIDALSQ
FFKLVFLAVALIVSIASIKYTENSDHTEEFYTLVLFATFGMMIVASANDLILLFCAFELASLATFALAGFEKQNARSLEG
AMKYFVIGSVSAALMLFGLSFVYGATGTTSIPLIAQNPGLLTGNPIGIVAIVLLTAGFGFKMALVPFHMWAPDTYQGSPS
VVSALLAAGSKKMGFVAAFRVFIIALAALQPDWQFMFTLLAVVTMTFGNVVAVAQTSVKRMLAYSSLAQAGYIAMAFAVM
TPVALAGGIMYTLAHAFMKAGAFIAAAAVVWMITSEKTGNLDIPDHLDSFRGLGKRMPLAALCMTVFVFALAGIPPTAGF
MAKFVLFSSTIQAGMTWLAVIAILNSALSLFYYARLVKYMYFMPPEGKTEKVSIPFPYAAALLVAVAGVLVMGLWPEPFV
ELAMKAAMVLVPF

Sequences:

>Translated_493_residues
MQEIMYLAPELVLVATGLVILLTGVFLSPQSKNILGYLATLGTLAAIFLTVKSFGLLTMEGFSVQYTIFSETLSIDALSQ
FFKLVFLAVALIVSIASIKYTENSDHTEEFYTLVLFATFGMMIVASANDLILLFCAFELASLATFALAGFEKQNARSLEG
AMKYFVIGSVSAALMLFGLSFVYGATGTTSIPLIAQNPGLLTGNPIGIVAIVLLTAGFGFKMALVPFHMWAPDTYQGSPS
VVSALLAAGSKKMGFVAAFRVFIIALAALQPDWQFMFTLLAVVTMTFGNVVAVAQTSVKRMLAYSSLAQAGYIAMAFAVM
TPVALAGGIMYTLAHAFMKAGAFIAAAAVVWMITSEKTGNLDIPDHLDSFRGLGKRMPLAALCMTVFVFALAGIPPTAGF
MAKFVLFSSTIQAGMTWLAVIAILNSALSLFYYARLVKYMYFMPPEGKTEKVSIPFPYAAALLVAVAGVLVMGLWPEPFV
ELAMKAAMVLVPF
>Mature_493_residues
MQEIMYLAPELVLVATGLVILLTGVFLSPQSKNILGYLATLGTLAAIFLTVKSFGLLTMEGFSVQYTIFSETLSIDALSQ
FFKLVFLAVALIVSIASIKYTENSDHTEEFYTLVLFATFGMMIVASANDLILLFCAFELASLATFALAGFEKQNARSLEG
AMKYFVIGSVSAALMLFGLSFVYGATGTTSIPLIAQNPGLLTGNPIGIVAIVLLTAGFGFKMALVPFHMWAPDTYQGSPS
VVSALLAAGSKKMGFVAAFRVFIIALAALQPDWQFMFTLLAVVTMTFGNVVAVAQTSVKRMLAYSSLAQAGYIAMAFAVM
TPVALAGGIMYTLAHAFMKAGAFIAAAAVVWMITSEKTGNLDIPDHLDSFRGLGKRMPLAALCMTVFVFALAGIPPTAGF
MAKFVLFSSTIQAGMTWLAVIAILNSALSLFYYARLVKYMYFMPPEGKTEKVSIPFPYAAALLVAVAGVLVMGLWPEPFV
ELAMKAAMVLVPF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=381, Percent_Identity=23.8845144356955, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI251831116, Length=286, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI145693160, Length=417, Percent_Identity=34.052757793765, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1788831, Length=365, Percent_Identity=30.4109589041096, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1788614, Length=401, Percent_Identity=25.6857855361596, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1788827, Length=360, Percent_Identity=25.5555555555556, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1788829, Length=413, Percent_Identity=25.4237288135593, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367154, Length=397, Percent_Identity=23.1738035264484, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788613, Length=360, Percent_Identity=26.6666666666667, Blast_Score=79, Evalue=8e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 52717; Mature: 52717

Theoretical pI: Translated: 8.15; Mature: 8.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
5.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEIMYLAPELVLVATGLVILLTGVFLSPQSKNILGYLATLGTLAAIFLTVKSFGLLTME
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEE
GFSVQYTIFSETLSIDALSQFFKLVFLAVALIVSIASIKYTENSDHTEEFYTLVLFATFG
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHH
MMIVASANDLILLFCAFELASLATFALAGFEKQNARSLEGAMKYFVIGSVSAALMLFGLS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVYGATGTTSIPLIAQNPGLLTGNPIGIVAIVLLTAGFGFKMALVPFHMWAPDTYQGSPS
HHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHEECCCCCCCCCHH
VVSALLAAGSKKMGFVAAFRVFIIALAALQPDWQFMFTLLAVVTMTFGNVVAVAQTSVKR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MLAYSSLAQAGYIAMAFAVMTPVALAGGIMYTLAHAFMKAGAFIAAAAVVWMITSEKTGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
LDIPDHLDSFRGLGKRMPLAALCMTVFVFALAGIPPTAGFMAKFVLFSSTIQAGMTWLAV
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAILNSALSLFYYARLVKYMYFMPPEGKTEKVSIPFPYAAALLVAVAGVLVMGLWPEPFV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHH
ELAMKAAMVLVPF
HHHHHHHHHCCCC
>Mature Secondary Structure
MQEIMYLAPELVLVATGLVILLTGVFLSPQSKNILGYLATLGTLAAIFLTVKSFGLLTME
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEE
GFSVQYTIFSETLSIDALSQFFKLVFLAVALIVSIASIKYTENSDHTEEFYTLVLFATFG
CCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHH
MMIVASANDLILLFCAFELASLATFALAGFEKQNARSLEGAMKYFVIGSVSAALMLFGLS
HHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FVYGATGTTSIPLIAQNPGLLTGNPIGIVAIVLLTAGFGFKMALVPFHMWAPDTYQGSPS
HHHCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHCCCCCEEHHHHHEECCCCCCCCCHH
VVSALLAAGSKKMGFVAAFRVFIIALAALQPDWQFMFTLLAVVTMTFGNVVAVAQTSVKR
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHH
MLAYSSLAQAGYIAMAFAVMTPVALAGGIMYTLAHAFMKAGAFIAAAAVVWMITSEKTGN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
LDIPDHLDSFRGLGKRMPLAALCMTVFVFALAGIPPTAGFMAKFVLFSSTIQAGMTWLAV
CCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
IAILNSALSLFYYARLVKYMYFMPPEGKTEKVSIPFPYAAALLVAVAGVLVMGLWPEPFV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCHHHH
ELAMKAAMVLVPF
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA