Click here to switch to the map view.

The map label for this gene is rpoH [H]

Identifier: 21228376

GI number: 21228376

Start: 2702561

End: 2702884

Strand: Reverse

Name: rpoH [H]

Synonym: MM_2274

Alternate gene names: 21228376

Gene position: 2702884-2702561 (Counterclockwise)

Preceding gene: 21228377

Following gene: 21228375

Centisome position: 65.98

GC content: 40.43

Gene sequence:

>324_bases
ATGTTCTTTATTATGACTGGCGGAAAGGCCATCCGCTGGAGAAATCTAATCAAGTTTTTTGAATGCTTTATTTTTGGAGG
AAAGGATTTGACAAAGTTCAGCCTGCTCGACCATGAGGCGGTCCCCAAGCATGAAATCATGTCTGAGGGCGAGTTAAAGT
CTGTTTTAAGCAAATATTTTATTGAAAAGGAACAACTTCCGAAAATCAAAGTGCAGGATCCTGTTTGTAAAGAAATAGGA
GCTGTCGTCGGAGATGTCGTGAAAATAACAAGAAAAAGTCAGACTGCAGGGGAGGCAGATTATTACAGACTCGTGATTGA
GTAA

Upstream 100 bases:

>100_bases
TAGAGGTGGAGAGATAAACAAACTGGGCCCGTAGCTCAGTCAGGCAGAGCGACTGGCTTTTAACCAGTCGGCCTAGGGTT
CAAATCCCTACGGGCCCGCC

Downstream 100 bases:

>100_bases
GCGGAGGGGAGTTAAAACCGCTTTCAAAATCATATTTTTTTCACTGAATATCTTTTTGAATCCCATGCACCATCATACGG
AAAGATTCAACGACTGCATA

Product: DNA-directed RNA polymerase subunit H

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 107

Protein sequence:

>107_residues
MFFIMTGGKAIRWRNLIKFFECFIFGGKDLTKFSLLDHEAVPKHEIMSEGELKSVLSKYFIEKEQLPKIKVQDPVCKEIG
AVVGDVVKITRKSQTAGEADYYRLVIE

Sequences:

>Translated_107_residues
MFFIMTGGKAIRWRNLIKFFECFIFGGKDLTKFSLLDHEAVPKHEIMSEGELKSVLSKYFIEKEQLPKIKVQDPVCKEIG
AVVGDVVKITRKSQTAGEADYYRLVIE
>Mature_107_residues
MFFIMTGGKAIRWRNLIKFFECFIFGGKDLTKFSLLDHEAVPKHEIMSEGELKSVLSKYFIEKEQLPKIKVQDPVCKEIG
AVVGDVVKITRKSQTAGEADYYRLVIE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG2012

COG function: function code K; DNA-directed RNA polymerase, subunit H, RpoH/RPB5

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the archaeal rpoH/eukaryotic RPB5 RNA polymerase subunit family [H]

Homologues:

Organism=Homo sapiens, GI14589951, Length=73, Percent_Identity=42.4657534246575, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17507947, Length=73, Percent_Identity=42.4657534246575, Blast_Score=63, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6319630, Length=73, Percent_Identity=41.0958904109589, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020609
- InterPro:   IPR000783
- InterPro:   IPR020608
- ProDom:   PD005155 [H]

Pfam domain/function: PF01191 RNA_pol_Rpb5_C [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 12274; Mature: 12274

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS01110 RNA_POL_H_23KD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFIMTGGKAIRWRNLIKFFECFIFGGKDLTKFSLLDHEAVPKHEIMSEGELKSVLSKYF
CEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHCCCHHHHHHHHHH
IEKEQLPKIKVQDPVCKEIGAVVGDVVKITRKSQTAGEADYYRLVIE
HCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC
>Mature Secondary Structure
MFFIMTGGKAIRWRNLIKFFECFIFGGKDLTKFSLLDHEAVPKHEIMSEGELKSVLSKYF
CEEEEECCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHHCCCHHHHHHHHHH
IEKEQLPKIKVQDPVCKEIGAVVGDVVKITRKSQTAGEADYYRLVIE
HCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]