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The map label for this gene is hypE

Identifier: 21228133

GI number: 21228133

Start: 2426798

End: 2428141

Strand: Direct

Name: hypE

Synonym: MM_2031

Alternate gene names: NA

Gene position: 2426798-2428141 (Clockwise)

Preceding gene: 21228132

Following gene: 21228136

Centisome position: 59.24

GC content: 46.58

Gene sequence:

>1344_bases
ATGGTTGTTATGGATATAGAAGGCTATGCAAAACGGGCTCTTAAAAAAGACCCTTCAAATGAAACCGGACTTGAAGAACA
GCTTGCTTCAAGAATACTTGAAATCAAGAGCATAAGCTCAAAAAGGGCTCATGAGATTGCAGCTGCAGTTATCTGCGAGG
CAAAAGCCACTCTTCATACCGAAGGAGATGTATTAAACCCCACTATTTCAGGAGTTGCTATGGGGGAGTTCGGTGTGGGC
TCAAGAGGCACAGGGGACTTTTACGTTCATTCCAAGCTTGGAGAGGTTATAGGCAACACGGGTGCGGTGGTTGATAGTTC
CCAGCTTGATGATTCCGGCGTTGTGAAAATAGGGGATGAATACCTTGTGGTTACAATTGACGGCATACATTCCCGCCTGA
GTGATTTCCCTTTCCTATCAGGTTTTCATGTAGCCAGAGCAGCCCTGCGTGATGTATATTCAATGGGAGCACGTCCCCTT
GCAATGCTTTCAGACATCCACGTTGCAGACGATGGGGACGTTGCAAAAATATTTGATCATATTGCAGGGATAACCACGGT
CTCGGAACTTACCGGAATTCCTCTTATTACCGGGAGCACTCTCCGTATAGGCGGGGATATGGTCATAGGAGAAAGAATGA
CAGGAGGCGTCGGAGCGGTTGGTGTTACTTCCTCCCTTACCTCACGAAACAGGACAAGGCCGGGAGACCTCATCCTTATG
ACTGAAGGCGCAGGAGGAGGAACGATTTCTACAACTGCACTTTATTACGATATGCATGACGTCGTGGAAGAGACCATAAA
CATCCGTTTTCTTGAAGCCTGTGAAGCCCTTCTGCAGTCCGGCCTGTATAAAAAAGTCCACTCCATGACCGATGTTACCA
ATGGAGGAATACGTGGGGATGCCAGAGAGATCTCAAAGACCGCAGGTGTAAAAATGGTCTTTGAAGAAGAAAAAATGCGG
GCTCTTGTAAACGCCAAGGTTCTCTCCATGCTTGAGCTTCTTAAAATCGATTATCTTGGTGTTTCTCTTGATGCCCTGCT
GGTCATTGCCCCTCCAGAATATGCCGGTGAAATTCTTGAAACCGTTCGGGCTGCCGGGGTTGAGATTGATATCATAGGCC
ATGTTGAAGAAGGAAGCGGGGCTGAAATTATTGTTAATGGAGAAGTCCGGGACTTTGCACCCAGGTTCAGGGAGTCAGCC
TATACTCCTGTTAAAAAGGTTCACGGGGAAGAGAATCCGAGAGACTTTGAAGAAATGAGGGATGCAATTGACAGGGCGGC
TGAGGAGGCTATAAATAAAAAATACAGGGTTCTTGAGAAAATAAAGAACAAGAGAAAAGATTAA

Upstream 100 bases:

>100_bases
ACTGATCAGGATTCAATTGAAATTAAACAGAAAACCGATACTTTAATTCCAAATTATCCTGTCCTGCTCCCTGTAAAGCA
GAGACAGTATCTGCGAGAGG

Downstream 100 bases:

>100_bases
GCTGAAATAAGGAAACACAACTCTGTATAAAGAAAAGCAGAAGAGAAAGGGAGGTTTATACTTTTCTTTTTATTACCAGC
ACTTCCCTTTCTTTTCCAAT

Product: hydrogenase expression/formation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MVVMDIEGYAKRALKKDPSNETGLEEQLASRILEIKSISSKRAHEIAAAVICEAKATLHTEGDVLNPTISGVAMGEFGVG
SRGTGDFYVHSKLGEVIGNTGAVVDSSQLDDSGVVKIGDEYLVVTIDGIHSRLSDFPFLSGFHVARAALRDVYSMGARPL
AMLSDIHVADDGDVAKIFDHIAGITTVSELTGIPLITGSTLRIGGDMVIGERMTGGVGAVGVTSSLTSRNRTRPGDLILM
TEGAGGGTISTTALYYDMHDVVEETINIRFLEACEALLQSGLYKKVHSMTDVTNGGIRGDAREISKTAGVKMVFEEEKMR
ALVNAKVLSMLELLKIDYLGVSLDALLVIAPPEYAGEILETVRAAGVEIDIIGHVEEGSGAEIIVNGEVRDFAPRFRESA
YTPVKKVHGEENPRDFEEMRDAIDRAAEEAINKKYRVLEKIKNKRKD

Sequences:

>Translated_447_residues
MVVMDIEGYAKRALKKDPSNETGLEEQLASRILEIKSISSKRAHEIAAAVICEAKATLHTEGDVLNPTISGVAMGEFGVG
SRGTGDFYVHSKLGEVIGNTGAVVDSSQLDDSGVVKIGDEYLVVTIDGIHSRLSDFPFLSGFHVARAALRDVYSMGARPL
AMLSDIHVADDGDVAKIFDHIAGITTVSELTGIPLITGSTLRIGGDMVIGERMTGGVGAVGVTSSLTSRNRTRPGDLILM
TEGAGGGTISTTALYYDMHDVVEETINIRFLEACEALLQSGLYKKVHSMTDVTNGGIRGDAREISKTAGVKMVFEEEKMR
ALVNAKVLSMLELLKIDYLGVSLDALLVIAPPEYAGEILETVRAAGVEIDIIGHVEEGSGAEIIVNGEVRDFAPRFRESA
YTPVKKVHGEENPRDFEEMRDAIDRAAEEAINKKYRVLEKIKNKRKD
>Mature_447_residues
MVVMDIEGYAKRALKKDPSNETGLEEQLASRILEIKSISSKRAHEIAAAVICEAKATLHTEGDVLNPTISGVAMGEFGVG
SRGTGDFYVHSKLGEVIGNTGAVVDSSQLDDSGVVKIGDEYLVVTIDGIHSRLSDFPFLSGFHVARAALRDVYSMGARPL
AMLSDIHVADDGDVAKIFDHIAGITTVSELTGIPLITGSTLRIGGDMVIGERMTGGVGAVGVTSSLTSRNRTRPGDLILM
TEGAGGGTISTTALYYDMHDVVEETINIRFLEACEALLQSGLYKKVHSMTDVTNGGIRGDAREISKTAGVKMVFEEEKMR
ALVNAKVLSMLELLKIDYLGVSLDALLVIAPPEYAGEILETVRAAGVEIDIIGHVEEGSGAEIIVNGEVRDFAPRFRESA
YTPVKKVHGEENPRDFEEMRDAIDRAAEEAINKKYRVLEKIKNKRKD

Specific function: Unknown

COG id: COG1973

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR009186
- InterPro:   IPR016188 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: NA

Molecular weight: Translated: 48151; Mature: 48151

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVMDIEGYAKRALKKDPSNETGLEEQLASRILEIKSISSKRAHEIAAAVICEAKATLHT
CEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHEEC
EGDVLNPTISGVAMGEFGVGSRGTGDFYVHSKLGEVIGNTGAVVDSSQLDDSGVVKIGDE
CCCCCCCCCCCEEECCCCCCCCCCCCEEEHHHHHHHHCCCCCEEECCCCCCCCCEEECCC
YLVVTIDGIHSRLSDFPFLSGFHVARAALRDVYSMGARPLAMLSDIHVADDGDVAKIFDH
EEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCEECCCCCHHHHHHH
IAGITTVSELTGIPLITGSTLRIGGDMVIGERMTGGVGAVGVTSSLTSRNRTRPGDLILM
HHHHHHHHHHCCCCEEECCEEEECCCEEECCCCCCCCCCCCHHHHHHHCCCCCCCCEEEE
TEGAGGGTISTTALYYDMHDVVEETINIRFLEACEALLQSGLYKKVHSMTDVTNGGIRGD
ECCCCCCCEEHHEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AREISKTAGVKMVFEEEKMRALVNAKVLSMLELLKIDYLGVSLDALLVIAPPEYAGEILE
HHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCHHHHHHHH
TVRAAGVEIDIIGHVEEGSGAEIIVNGEVRDFAPRFRESAYTPVKKVHGEENPRDFEEMR
HHHHCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHH
DAIDRAAEEAINKKYRVLEKIKNKRKD
HHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MVVMDIEGYAKRALKKDPSNETGLEEQLASRILEIKSISSKRAHEIAAAVICEAKATLHT
CEEEECCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHEEC
EGDVLNPTISGVAMGEFGVGSRGTGDFYVHSKLGEVIGNTGAVVDSSQLDDSGVVKIGDE
CCCCCCCCCCCEEECCCCCCCCCCCCEEEHHHHHHHHCCCCCEEECCCCCCCCCEEECCC
YLVVTIDGIHSRLSDFPFLSGFHVARAALRDVYSMGARPLAMLSDIHVADDGDVAKIFDH
EEEEEECCHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHCCEECCCCCHHHHHHH
IAGITTVSELTGIPLITGSTLRIGGDMVIGERMTGGVGAVGVTSSLTSRNRTRPGDLILM
HHHHHHHHHHCCCCEEECCEEEECCCEEECCCCCCCCCCCCHHHHHHHCCCCCCCCEEEE
TEGAGGGTISTTALYYDMHDVVEETINIRFLEACEALLQSGLYKKVHSMTDVTNGGIRGD
ECCCCCCCEEHHEEEHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AREISKTAGVKMVFEEEKMRALVNAKVLSMLELLKIDYLGVSLDALLVIAPPEYAGEILE
HHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEEEECCHHHHHHHH
TVRAAGVEIDIIGHVEEGSGAEIIVNGEVRDFAPRFRESAYTPVKKVHGEENPRDFEEMR
HHHHCCCEEEEEEEEECCCCCEEEECCCHHHHHHHHHHHCCCCHHHHCCCCCCHHHHHHH
DAIDRAAEEAINKKYRVLEKIKNKRKD
HHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]