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The map label for this gene is 21227975

Identifier: 21227975

GI number: 21227975

Start: 2225553

End: 2226770

Strand: Reverse

Name: 21227975

Synonym: MM_1873

Alternate gene names: NA

Gene position: 2226770-2225553 (Counterclockwise)

Preceding gene: 21227984

Following gene: 21227974

Centisome position: 54.36

GC content: 47.04

Gene sequence:

>1218_bases
ATGAAAGTAGTCCTTGATCCCGTGCATGGTTATATCGAACTGGATGAAGTTGTTCAGGAGCTTCTGGACACCCCACAGAT
ACAGCGCCTCAGGAGAGTCAGGCAGCTTGGATTTTCAAACCTTGTATATCCGGGAGCAAACCATACACGTTTTGAACACT
CACTCGGAACCATGCACCTTGCCTCCATGCTGATGAAAAACCTCGACTCAATTGACGAGGATAAAAAACTGGAGATAAGG
GTTGCCTCCCTTTTGCATGATGTGGGGCACGGCCCATTTTCCCATGTAACAGAGAATGTTATTTATAAATATACCCGGCG
CCGGCATGACGAGATAAAGGAAATCCTGGGGAAAGGGGAAATAAAAGAAATCCTGAAAAAATACGGGATTTACCCCGGTG
AACTTGCAAAGCACGTCGAAGGCGAGACATCTTTGGGGCAGATTTTAAGCAGTGAGATCGATGTGGACAGGATGGACTAC
CTTGTCCGGGATGCACATTATACCGGCGTTGCTTTCGGAGTTGTGGACTACAACCGCCTGATTAACCAGATGAGTTTTCA
CGAAGACAGGCTTGTTGTTGACCAGGGAGGACTCAAAGCAGCCGAATCTCTCCTGGTCTCACGCTTCTGGATGAATACCT
CGGTTTATTATCACCATGTTACCAGAATATCTGAAGCCATGTGCTCAAAAGCAGTTGAGCATATGATCGAGGACGGGGAA
ATGGACCCGTTCCGGCTAAGGCAGATGGACGATATAGACTTAATAGCCGCAATGCGAAGCTCAAAGGGGTATGGAGGAGA
ACTTGCAAGGCGGCTCGATTCACGCAACCTCTATAAACGGGCGCTCTATACAGGGCTTGAGGATGCAGGGAAAGGAGTAC
TCAAACACCGGGATAAAATAGAGAGAGCAGAGAAGGAAATCGCAGAACTTGCCGGAGTGGACCAGGAATGTGTGCTTGTG
GACATCCCGAAAACCCCTGAAATGCTTGAAATGAAAGCAATGATAAAAACAGACCATAAACTAGTCTCCCTTAACGAAGC
TTCGCACTTCGTATCCATATTGCAGGAGGCTCACATGGACAACTGGAGAATGGGAGTTTACTGCCCGAGGGAACACTGTG
AAGCTGTGGGGAAGGCTGCAAAGGAATACTTTAACATAAAAAAAGTCACAAAACAATTCAAGCTGAGCGATCTGGAAAAT
ACTAAAGTGCAGGAGTAA

Upstream 100 bases:

>100_bases
ATATAGCATTCGGGCAGCAGGTGCCCTGTAATTTACATCTTAAGTAATAGCATCAAAGTAATAGATACAGCAATATATAA
TGACATCTGTCTAAAGATTA

Downstream 100 bases:

>100_bases
AATTTTTGTTTACCGTTACAAGGAAAGCCAGCAGGATAGAAATCACTCTCGAAGTGAAAAAACTGGGGGAAGACTACCTA
TTAACCCTGACCGGCGGAAA

Product: phosphohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 405

Protein sequence:

>405_residues
MKVVLDPVHGYIELDEVVQELLDTPQIQRLRRVRQLGFSNLVYPGANHTRFEHSLGTMHLASMLMKNLDSIDEDKKLEIR
VASLLHDVGHGPFSHVTENVIYKYTRRRHDEIKEILGKGEIKEILKKYGIYPGELAKHVEGETSLGQILSSEIDVDRMDY
LVRDAHYTGVAFGVVDYNRLINQMSFHEDRLVVDQGGLKAAESLLVSRFWMNTSVYYHHVTRISEAMCSKAVEHMIEDGE
MDPFRLRQMDDIDLIAAMRSSKGYGGELARRLDSRNLYKRALYTGLEDAGKGVLKHRDKIERAEKEIAELAGVDQECVLV
DIPKTPEMLEMKAMIKTDHKLVSLNEASHFVSILQEAHMDNWRMGVYCPREHCEAVGKAAKEYFNIKKVTKQFKLSDLEN
TKVQE

Sequences:

>Translated_405_residues
MKVVLDPVHGYIELDEVVQELLDTPQIQRLRRVRQLGFSNLVYPGANHTRFEHSLGTMHLASMLMKNLDSIDEDKKLEIR
VASLLHDVGHGPFSHVTENVIYKYTRRRHDEIKEILGKGEIKEILKKYGIYPGELAKHVEGETSLGQILSSEIDVDRMDY
LVRDAHYTGVAFGVVDYNRLINQMSFHEDRLVVDQGGLKAAESLLVSRFWMNTSVYYHHVTRISEAMCSKAVEHMIEDGE
MDPFRLRQMDDIDLIAAMRSSKGYGGELARRLDSRNLYKRALYTGLEDAGKGVLKHRDKIERAEKEIAELAGVDQECVLV
DIPKTPEMLEMKAMIKTDHKLVSLNEASHFVSILQEAHMDNWRMGVYCPREHCEAVGKAAKEYFNIKKVTKQFKLSDLEN
TKVQE
>Mature_405_residues
MKVVLDPVHGYIELDEVVQELLDTPQIQRLRRVRQLGFSNLVYPGANHTRFEHSLGTMHLASMLMKNLDSIDEDKKLEIR
VASLLHDVGHGPFSHVTENVIYKYTRRRHDEIKEILGKGEIKEILKKYGIYPGELAKHVEGETSLGQILSSEIDVDRMDY
LVRDAHYTGVAFGVVDYNRLINQMSFHEDRLVVDQGGLKAAESLLVSRFWMNTSVYYHHVTRISEAMCSKAVEHMIEDGE
MDPFRLRQMDDIDLIAAMRSSKGYGGELARRLDSRNLYKRALYTGLEDAGKGVLKHRDKIERAEKEIAELAGVDQECVLV
DIPKTPEMLEMKAMIKTDHKLVSLNEASHFVSILQEAHMDNWRMGVYCPREHCEAVGKAAKEYFNIKKVTKQFKLSDLEN
TKVQE

Specific function: Unknown

COG id: COG1078

COG function: function code R; HD superfamily phosphohydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HD domain [H]

Homologues:

Organism=Homo sapiens, GI38016914, Length=276, Percent_Identity=31.8840579710145, Blast_Score=128, Evalue=8e-30,
Organism=Caenorhabditis elegans, GI17537829, Length=311, Percent_Identity=29.5819935691318, Blast_Score=99, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17537827, Length=311, Percent_Identity=29.5819935691318, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI221512937, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24666702, Length=194, Percent_Identity=29.8969072164948, Blast_Score=66, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003607
- InterPro:   IPR006675
- InterPro:   IPR011991 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 46443; Mature: 46443

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVVLDPVHGYIELDEVVQELLDTPQIQRLRRVRQLGFSNLVYPGANHTRFEHSLGTMHL
CCEEEECCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
ASMLMKNLDSIDEDKKLEIRVASLLHDVGHGPFSHVTENVIYKYTRRRHDEIKEILGKGE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IKEILKKYGIYPGELAKHVEGETSLGQILSSEIDVDRMDYLVRDAHYTGVAFGVVDYNRL
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEHHHHHHHH
INQMSFHEDRLVVDQGGLKAAESLLVSRFWMNTSVYYHHVTRISEAMCSKAVEHMIEDGE
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
MDPFRLRQMDDIDLIAAMRSSKGYGGELARRLDSRNLYKRALYTGLEDAGKGVLKHRDKI
CCHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHH
ERAEKEIAELAGVDQECVLVDIPKTPEMLEMKAMIKTDHKLVSLNEASHFVSILQEAHMD
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCC
NWRMGVYCPREHCEAVGKAAKEYFNIKKVTKQFKLSDLENTKVQE
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKVVLDPVHGYIELDEVVQELLDTPQIQRLRRVRQLGFSNLVYPGANHTRFEHSLGTMHL
CCEEEECCCCCEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
ASMLMKNLDSIDEDKKLEIRVASLLHDVGHGPFSHVTENVIYKYTRRRHDEIKEILGKGE
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCH
IKEILKKYGIYPGELAKHVEGETSLGQILSSEIDVDRMDYLVRDAHYTGVAFGVVDYNRL
HHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCEEHHHHHHHH
INQMSFHEDRLVVDQGGLKAAESLLVSRFWMNTSVYYHHVTRISEAMCSKAVEHMIEDGE
HHHHHHCCCCEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCC
MDPFRLRQMDDIDLIAAMRSSKGYGGELARRLDSRNLYKRALYTGLEDAGKGVLKHRDKI
CCHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHCCHHHHHHHHH
ERAEKEIAELAGVDQECVLVDIPKTPEMLEMKAMIKTDHKLVSLNEASHFVSILQEAHMD
HHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCC
NWRMGVYCPREHCEAVGKAAKEYFNIKKVTKQFKLSDLENTKVQE
CCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]