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The map label for this gene is idsA [H]

Identifier: 21227869

GI number: 21227869

Start: 2107673

End: 2108647

Strand: Direct

Name: idsA [H]

Synonym: MM_1767

Alternate gene names: 21227869

Gene position: 2107673-2108647 (Clockwise)

Preceding gene: 21227868

Following gene: 21227871

Centisome position: 51.45

GC content: 48.41

Gene sequence:

>975_bases
GTGATGCTTATGACGCTTGTTGATGAAATTAAAAATCGAAGTTCCCATGTTGATGCTGCAATCGACGAATTGCTTCCGGT
AACCCGGCCTGAAGAGCTGTATAAAGCTTCCCGTTACCTCGTGGACGCCGGTGGGAAGCGCCTTCGTCCGGCAGTCCTCA
TCCTGGCTGCTGAAGCTGTCGGTTCCAATCTCAGGTCTGTTTTGCCCGCAGCAGTCGCGGTGGAACTTGTGCACAATTTC
ACTCTGATCCATGACGACATTATGGATAGGGATGATATCCGCAGGGGAATGCCTGCAGTTCACGTAAAATGGGGAGAAGC
CGGAGCAATTCTTGCCGGCGACACCCTTTATTCCAAAGCCTTCGAAATCCTCTCAAAAGTCGAAAACGAGCCTGTGAGGG
TTTTAAAGTGCATGGATGTCCTTTCAAAGACCTGCACCGAAATCTGCGAAGGCCAGTGGCTCGATATGGATTTCGAAACC
CGGAAAAAGGTTACTGAATCCGAGTACCTTGAGATGGTGGAAAAGAAGACCTCTGTCCTCTATGCAGCCGCAGCCAAAAT
CGGCGCCCTTTTAGGAGGGGCTTCTGACGAAGTTGCCGAGGCTTTATCCGAGTACGGACGCCTCATAGGAATAGGCTTCC
AGATGTATGATGACGTCCTTGATATGACCGCACCTGAAGAAGTTCTTGGAAAGGTAAGGGGCAGCGACCTTATGGAAGGA
AAATACACCCTTATTGTCATAAATGCTTTCGAGAAAGGCGTGAAGCTGGATATTTTCGGAAAAGGTGAAGCAACTCTCGA
AGAGACCGAAGCGGCAGTCAGGACTCTTACAGAATGCGGGTCTCTCGATTATGTGAAAAACCTTGCAATTTCATATATAG
AAGAAGGCAAAGAAAAACTGGATGTCCTCAGGGACTGTCCTGAAAAAACCCTTCTCCTGCAGATTGCTGACTATATGATC
TCACGAGAATACTAA

Upstream 100 bases:

>100_bases
AAGATGCGGGGTATGTACTCGGAGATACCGTACACCTTCTCAGAAATGGCGAAGTGTTATATATAGAGGAGTAACTCTAT
AATGAAAATCCCGTGTTCTT

Downstream 100 bases:

>100_bases
AGATGGGCTAATTTTGCTCATCTACATTTCGATTTCTTTTTGATCCCCTTTTTTTTGTATTTTCTTTTGATTTAACGATT
AAAGTAGCTTTGTTACAGTG

Product: dimethylallyltransferase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MMLMTLVDEIKNRSSHVDAAIDELLPVTRPEELYKASRYLVDAGGKRLRPAVLILAAEAVGSNLRSVLPAAVAVELVHNF
TLIHDDIMDRDDIRRGMPAVHVKWGEAGAILAGDTLYSKAFEILSKVENEPVRVLKCMDVLSKTCTEICEGQWLDMDFET
RKKVTESEYLEMVEKKTSVLYAAAAKIGALLGGASDEVAEALSEYGRLIGIGFQMYDDVLDMTAPEEVLGKVRGSDLMEG
KYTLIVINAFEKGVKLDIFGKGEATLEETEAAVRTLTECGSLDYVKNLAISYIEEGKEKLDVLRDCPEKTLLLQIADYMI
SREY

Sequences:

>Translated_324_residues
MMLMTLVDEIKNRSSHVDAAIDELLPVTRPEELYKASRYLVDAGGKRLRPAVLILAAEAVGSNLRSVLPAAVAVELVHNF
TLIHDDIMDRDDIRRGMPAVHVKWGEAGAILAGDTLYSKAFEILSKVENEPVRVLKCMDVLSKTCTEICEGQWLDMDFET
RKKVTESEYLEMVEKKTSVLYAAAAKIGALLGGASDEVAEALSEYGRLIGIGFQMYDDVLDMTAPEEVLGKVRGSDLMEG
KYTLIVINAFEKGVKLDIFGKGEATLEETEAAVRTLTECGSLDYVKNLAISYIEEGKEKLDVLRDCPEKTLLLQIADYMI
SREY
>Mature_324_residues
MMLMTLVDEIKNRSSHVDAAIDELLPVTRPEELYKASRYLVDAGGKRLRPAVLILAAEAVGSNLRSVLPAAVAVELVHNF
TLIHDDIMDRDDIRRGMPAVHVKWGEAGAILAGDTLYSKAFEILSKVENEPVRVLKCMDVLSKTCTEICEGQWLDMDFET
RKKVTESEYLEMVEKKTSVLYAAAAKIGALLGGASDEVAEALSEYGRLIGIGFQMYDDVLDMTAPEEVLGKVRGSDLMEG
KYTLIVINAFEKGVKLDIFGKGEATLEETEAAVRTLTECGSLDYVKNLAISYIEEGKEKLDVLRDCPEKTLLLQIADYMI
SREY

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=300, Percent_Identity=29.6666666666667, Blast_Score=132, Evalue=4e-31,
Organism=Homo sapiens, GI4758430, Length=300, Percent_Identity=24, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI83700220, Length=300, Percent_Identity=24, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1789578, Length=315, Percent_Identity=33.3333333333333, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1786623, Length=221, Percent_Identity=38.0090497737557, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17505681, Length=328, Percent_Identity=26.8292682926829, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17508563, Length=225, Percent_Identity=28.4444444444444, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325188, Length=269, Percent_Identity=24.1635687732342, Blast_Score=80, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24651612, Length=304, Percent_Identity=30.2631578947368, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI281365769, Length=241, Percent_Identity=26.1410788381743, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI24660002, Length=241, Percent_Identity=26.1410788381743, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 35881; Mature: 35881

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLMTLVDEIKNRSSHVDAAIDELLPVTRPEELYKASRYLVDAGGKRLRPAVLILAAEAV
CHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHH
GSNLRSVLPAAVAVELVHNFTLIHDDIMDRDDIRRGMPAVHVKWGEAGAILAGDTLYSKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCEEECHHHHHHH
FEILSKVENEPVRVLKCMDVLSKTCTEICEGQWLDMDFETRKKVTESEYLEMVEKKTSVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YAAAAKIGALLGGASDEVAEALSEYGRLIGIGFQMYDDVLDMTAPEEVLGKVRGSDLMEG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
KYTLIVINAFEKGVKLDIFGKGEATLEETEAAVRTLTECGSLDYVKNLAISYIEEGKEKL
CEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DVLRDCPEKTLLLQIADYMISREY
HHHHHCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMLMTLVDEIKNRSSHVDAAIDELLPVTRPEELYKASRYLVDAGGKRLRPAVLILAAEAV
CHHHHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCHHHHEEEHHHH
GSNLRSVLPAAVAVELVHNFTLIHDDIMDRDDIRRGMPAVHVKWGEAGAILAGDTLYSKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEEECCCCCEEECHHHHHHH
FEILSKVENEPVRVLKCMDVLSKTCTEICEGQWLDMDFETRKKVTESEYLEMVEKKTSVL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
YAAAAKIGALLGGASDEVAEALSEYGRLIGIGFQMYDDVLDMTAPEEVLGKVRGSDLMEG
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCC
KYTLIVINAFEKGVKLDIFGKGEATLEETEAAVRTLTECGSLDYVKNLAISYIEEGKEKL
CEEEEEEEECCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
DVLRDCPEKTLLLQIADYMISREY
HHHHHCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7979381 [H]