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The map label for this gene is ybdE [C]

Identifier: 21227655

GI number: 21227655

Start: 1852556

End: 1854922

Strand: Reverse

Name: ybdE [C]

Synonym: MM_1553

Alternate gene names: 21227655

Gene position: 1854922-1852556 (Counterclockwise)

Preceding gene: 21227659

Following gene: 21227654

Centisome position: 45.28

GC content: 43.73

Gene sequence:

>2367_bases
ATGAGAGGATTTACTATTAAAAATACTTTTGAAAAACTGGGATTTTTTATTCAGAATAACCGTTTTTCCATACTTCTGGT
AGCCTTTCTGTTCATAGTCATAGCAACACAGGGCGCACAAAATATAGAGATGGCTTCAGGAACAGAGACATTTGTAGGGA
AAGACTCCCCTCTCTATCAGGACTACGATCACCTTTATCAAAAAATATTTCAGACTCAATCAATTGTGGTAATGGTAGAG
GGCAATGAGGTGAAAAACGCTGACCTGATGAAAGCCGTGGACAGAATGGAACACCAGCTCCAGGGCACTGAGGGTGTAAT
AGAAACCACAAGCCCTGCCTCCCTGATCAAAATGGTTAATTACCAGATGACAGGAAGATACGTGATTCCAGATACCGATA
AAGAGATTGAAGCTATTATAGATGGAAACCCTGAAATTTTCGGACAGATTGTCCCTGATAATACTCACATTCTGATTTCA
GTAGTAATGGCCGGCTCAACCAGTGACGCTGCACAGGAAGATATCCTTTATGCCACTGAAGATTCGGTTTCATTTGCAGA
ATTTCCACCTTCTTACAACATCATCGTCACAGGTGACCCGCCCTTCATGGTCTCCATGAACTACGAAATGAATTCCAGCA
TGGGTGTGCTTCTGGGACTTTCCGGTCTTTTCATGGTTATCATATTATTTTTCGTGTTCAAACACGTCCGATGGGGCCTT
CTCCCTCTACCGGTAGTCCTTCTCGGAATTATTTACACCTTTGGAGCTATGGGCTATATCGGAATTTCCCTTTCCATGGT
CTCAATGGCTGCGTTCCCGATCCTCATAGGCGTGGGGATAGACTATGCTATCCAGTTCCATAACAGGCTTGAAGAAGAAC
TGCACAAAAGCGAGAGCAAGGAAAGGGCAGTTGTAGAAACCATAAAGAATACTGGACCTGCAGTTTTAATAGCTCTGGGA
ATGACAGCGCTTGGCTTTGTATCTCTCTTTACATCTTCAGTGCCTATGATCCAGGACTTTGGAAAACTGCTCCTGATAGG
CATTATAATGTGTTATCTCTCCTCCATATTCGTGGGAATTACAACAATTTCACTATTTGATAAGTATTCGGACAAAAATC
CTCTAAAGAAAATTGCCAGAAAGATAAAACCGGCAGGTCTGGATAAAAAGAAAAAGTCGGAAAAAAAGAGAGGAGAGGGG
CATATAACAGAGAAATTGCTCCAGAAAACTACCGACCTGACAATCAGATACGATATTATTGTACTGGGAATTGCAAGCCT
GCTCTGTTTAGGCGGGCTTTATGTGGATCAGTCAGTACCAATTGAGACTGACGTGCAAACATTCGTTCCCCAGGATATGC
CTGCTCTTGTGGACCTCGCGCATATGGGAGACATCATGGGCGGGACAGATGAACTGAACCTTATTATCAAGGTTAAAGAT
ACAGCGAATCCGGATGTTCTGAAGTGGATAGATCGGTTTTCCGAGCATGAAGTTGAAGGAAGAAAGCACATTTACAGCGC
TTCTAGCATTGTACCCCTGGTGAAGGAAAGGAACGGAGGCACGATCCCGGATACAAGCCAGGAAATAGAAGCTATTTATG
CTGAGATCCCGGAATCTCAGAAAGACCGTTACATGTACGGGAAAAATATGCTTCTCCTTAATTTCAATATAGGAAATGCG
GTTGCGGACATTAAAGTAACAGGTATTCAGGAACTAACTGACATTGTTAAACAGGATATGCAATGGATGCCAGCCCCTCC
GGGTACATCTGTCACTATTACCGGGAACAATGTTGTATTTATAGAAGTTATTACAGCTCTTACCAGTGGTAGAGTAGCAA
TGACTTTCCTGGGGCTTATTCTTGTGCTTGCAGGGCTTTTCGTTGTTTACAGAGACTGGCTGAAAGCGGTAGTCCCTATC
ATCCCCATGTTCATAGTAATAGGCTGGTCAGGAGGAGTTATGTATTACCTTGATATCGAATACACTCCCATGACAGCAAC
TCTTGGAGCTCTGATTCTGGGAGTAGGGTCTGAGTATGCGATCCTTATGATGGAGCGTTACTTTGAGGAAAAAGATGCAG
GTGCAACTCCTATGGAAGCTATCCATATGACCAGTGCCAAAATAGGAACTGCAATCATTGCTTCAGGAGCGACCACTGTA
TTTGGATTCCTGGCACTGGTCGTTTCCCCCTTCCCTATGATCAGCAATTTCGGAATAGTTACGGTTGTGGATGTCCTGAT
GGCTCTCCTGGCAACTTTTGTAGTTTTCCCACCGCTTATAGTGGTCCTTGATACCTGGAGAGAAAAGAGGAGAGGAGCCA
CGGCAGAGAAAGAGGCAAAAAAACAAATTCAGGGGGCAGATGTATGA

Upstream 100 bases:

>100_bases
TGTGTGAATAAGCCTTGAATGGCAGATCTCCAGCCTGAATAAAGACAGGCAGGTCAGATAAATGCAACAAGGCCCCTAAA
TTGTATGGATACTAAAAATT

Downstream 100 bases:

>100_bases
TACAAGCACCCGGAAAAACCAGACAAGAAATAATGAAGAAAGCTTCGAGATTTACATTAGTCCTGTTAATAATTTCAATC
ACTGCATTCCCAGCCCTTGG

Product: RND superfamily protein

Products: Proton [Cytoplasm]; silver [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 788; Mature: 788

Protein sequence:

>788_residues
MRGFTIKNTFEKLGFFIQNNRFSILLVAFLFIVIATQGAQNIEMASGTETFVGKDSPLYQDYDHLYQKIFQTQSIVVMVE
GNEVKNADLMKAVDRMEHQLQGTEGVIETTSPASLIKMVNYQMTGRYVIPDTDKEIEAIIDGNPEIFGQIVPDNTHILIS
VVMAGSTSDAAQEDILYATEDSVSFAEFPPSYNIIVTGDPPFMVSMNYEMNSSMGVLLGLSGLFMVIILFFVFKHVRWGL
LPLPVVLLGIIYTFGAMGYIGISLSMVSMAAFPILIGVGIDYAIQFHNRLEEELHKSESKERAVVETIKNTGPAVLIALG
MTALGFVSLFTSSVPMIQDFGKLLLIGIIMCYLSSIFVGITTISLFDKYSDKNPLKKIARKIKPAGLDKKKKSEKKRGEG
HITEKLLQKTTDLTIRYDIIVLGIASLLCLGGLYVDQSVPIETDVQTFVPQDMPALVDLAHMGDIMGGTDELNLIIKVKD
TANPDVLKWIDRFSEHEVEGRKHIYSASSIVPLVKERNGGTIPDTSQEIEAIYAEIPESQKDRYMYGKNMLLLNFNIGNA
VADIKVTGIQELTDIVKQDMQWMPAPPGTSVTITGNNVVFIEVITALTSGRVAMTFLGLILVLAGLFVVYRDWLKAVVPI
IPMFIVIGWSGGVMYYLDIEYTPMTATLGALILGVGSEYAILMMERYFEEKDAGATPMEAIHMTSAKIGTAIIASGATTV
FGFLALVVSPFPMISNFGIVTVVDVLMALLATFVVFPPLIVVLDTWREKRRGATAEKEAKKQIQGADV

Sequences:

>Translated_788_residues
MRGFTIKNTFEKLGFFIQNNRFSILLVAFLFIVIATQGAQNIEMASGTETFVGKDSPLYQDYDHLYQKIFQTQSIVVMVE
GNEVKNADLMKAVDRMEHQLQGTEGVIETTSPASLIKMVNYQMTGRYVIPDTDKEIEAIIDGNPEIFGQIVPDNTHILIS
VVMAGSTSDAAQEDILYATEDSVSFAEFPPSYNIIVTGDPPFMVSMNYEMNSSMGVLLGLSGLFMVIILFFVFKHVRWGL
LPLPVVLLGIIYTFGAMGYIGISLSMVSMAAFPILIGVGIDYAIQFHNRLEEELHKSESKERAVVETIKNTGPAVLIALG
MTALGFVSLFTSSVPMIQDFGKLLLIGIIMCYLSSIFVGITTISLFDKYSDKNPLKKIARKIKPAGLDKKKKSEKKRGEG
HITEKLLQKTTDLTIRYDIIVLGIASLLCLGGLYVDQSVPIETDVQTFVPQDMPALVDLAHMGDIMGGTDELNLIIKVKD
TANPDVLKWIDRFSEHEVEGRKHIYSASSIVPLVKERNGGTIPDTSQEIEAIYAEIPESQKDRYMYGKNMLLLNFNIGNA
VADIKVTGIQELTDIVKQDMQWMPAPPGTSVTITGNNVVFIEVITALTSGRVAMTFLGLILVLAGLFVVYRDWLKAVVPI
IPMFIVIGWSGGVMYYLDIEYTPMTATLGALILGVGSEYAILMMERYFEEKDAGATPMEAIHMTSAKIGTAIIASGATTV
FGFLALVVSPFPMISNFGIVTVVDVLMALLATFVVFPPLIVVLDTWREKRRGATAEKEAKKQIQGADV
>Mature_788_residues
MRGFTIKNTFEKLGFFIQNNRFSILLVAFLFIVIATQGAQNIEMASGTETFVGKDSPLYQDYDHLYQKIFQTQSIVVMVE
GNEVKNADLMKAVDRMEHQLQGTEGVIETTSPASLIKMVNYQMTGRYVIPDTDKEIEAIIDGNPEIFGQIVPDNTHILIS
VVMAGSTSDAAQEDILYATEDSVSFAEFPPSYNIIVTGDPPFMVSMNYEMNSSMGVLLGLSGLFMVIILFFVFKHVRWGL
LPLPVVLLGIIYTFGAMGYIGISLSMVSMAAFPILIGVGIDYAIQFHNRLEEELHKSESKERAVVETIKNTGPAVLIALG
MTALGFVSLFTSSVPMIQDFGKLLLIGIIMCYLSSIFVGITTISLFDKYSDKNPLKKIARKIKPAGLDKKKKSEKKRGEG
HITEKLLQKTTDLTIRYDIIVLGIASLLCLGGLYVDQSVPIETDVQTFVPQDMPALVDLAHMGDIMGGTDELNLIIKVKD
TANPDVLKWIDRFSEHEVEGRKHIYSASSIVPLVKERNGGTIPDTSQEIEAIYAEIPESQKDRYMYGKNMLLLNFNIGNA
VADIKVTGIQELTDIVKQDMQWMPAPPGTSVTITGNNVVFIEVITALTSGRVAMTFLGLILVLAGLFVVYRDWLKAVVPI
IPMFIVIGWSGGVMYYLDIEYTPMTATLGALILGVGSEYAILMMERYFEEKDAGATPMEAIHMTSAKIGTAIIASGATTV
FGFLALVVSPFPMISNFGIVTVVDVLMALLATFVVFPPLIVVLDTWREKRRGATAEKEAKKQIQGADV

Specific function: Could Be A Drug Efflux Pump. [C]

COG id: COG1033

COG function: function code R; Predicted exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 86718; Mature: 86718

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGFTIKNTFEKLGFFIQNNRFSILLVAFLFIVIATQGAQNIEMASGTETFVGKDSPLYQ
CCCCCHHHHHHHHCEEEECCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCHH
DYDHLYQKIFQTQSIVVMVEGNEVKNADLMKAVDRMEHQLQGTEGVIETTSPASLIKMVN
HHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHH
YQMTGRYVIPDTDKEIEAIIDGNPEIFGQIVPDNTHILISVVMAGSTSDAAQEDILYATE
HEECCCEECCCCCCCHHEEECCCHHHEEEECCCCCEEEEEEEEECCCCCCHHHCCEEECC
DSVSFAEFPPSYNIIVTGDPPFMVSMNYEMNSSMGVLLGLSGLFMVIILFFVFKHVRWGL
CCCCHHCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LPLPVVLLGIIYTFGAMGYIGISLSMVSMAAFPILIGVGIDYAIQFHNRLEEELHKSESK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHH
ERAVVETIKNTGPAVLIALGMTALGFVSLFTSSVPMIQDFGKLLLIGIIMCYLSSIFVGI
HHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TTISLFDKYSDKNPLKKIARKIKPAGLDKKKKSEKKRGEGHITEKLLQKTTDLTIRYDII
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCEEEHHHH
VLGIASLLCLGGLYVDQSVPIETDVQTFVPQDMPALVDLAHMGDIMGGTDELNLIIKVKD
HHHHHHHHHHCCEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEC
TANPDVLKWIDRFSEHEVEGRKHIYSASSIVPLVKERNGGTIPDTSQEIEAIYAEIPESQ
CCCHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCC
KDRYMYGKNMLLLNFNIGNAVADIKVTGIQELTDIVKQDMQWMPAPPGTSVTITGNNVVF
CCCEEECCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEE
IEVITALTSGRVAMTFLGLILVLAGLFVVYRDWLKAVVPIIPMFIVIGWSGGVMYYLDIE
EEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEE
YTPMTATLGALILGVGSEYAILMMERYFEEKDAGATPMEAIHMTSAKIGTAIIASGATTV
ECCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
FGFLALVVSPFPMISNFGIVTVVDVLMALLATFVVFPPLIVVLDTWREKRRGATAEKEAK
HHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KQIQGADV
HHHCCCCC
>Mature Secondary Structure
MRGFTIKNTFEKLGFFIQNNRFSILLVAFLFIVIATQGAQNIEMASGTETFVGKDSPLYQ
CCCCCHHHHHHHHCEEEECCCHHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCHH
DYDHLYQKIFQTQSIVVMVEGNEVKNADLMKAVDRMEHQLQGTEGVIETTSPASLIKMVN
HHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHH
YQMTGRYVIPDTDKEIEAIIDGNPEIFGQIVPDNTHILISVVMAGSTSDAAQEDILYATE
HEECCCEECCCCCCCHHEEECCCHHHEEEECCCCCEEEEEEEEECCCCCCHHHCCEEECC
DSVSFAEFPPSYNIIVTGDPPFMVSMNYEMNSSMGVLLGLSGLFMVIILFFVFKHVRWGL
CCCCHHCCCCCCEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
LPLPVVLLGIIYTFGAMGYIGISLSMVSMAAFPILIGVGIDYAIQFHNRLEEELHKSESK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCHH
ERAVVETIKNTGPAVLIALGMTALGFVSLFTSSVPMIQDFGKLLLIGIIMCYLSSIFVGI
HHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
TTISLFDKYSDKNPLKKIARKIKPAGLDKKKKSEKKRGEGHITEKLLQKTTDLTIRYDII
HHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHCCEEEHHHH
VLGIASLLCLGGLYVDQSVPIETDVQTFVPQDMPALVDLAHMGDIMGGTDELNLIIKVKD
HHHHHHHHHHCCEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEC
TANPDVLKWIDRFSEHEVEGRKHIYSASSIVPLVKERNGGTIPDTSQEIEAIYAEIPESQ
CCCHHHHHHHHHHHHHCCCCHHHHHCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCC
KDRYMYGKNMLLLNFNIGNAVADIKVTGIQELTDIVKQDMQWMPAPPGTSVTITGNNVVF
CCCEEECCCEEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEE
IEVITALTSGRVAMTFLGLILVLAGLFVVYRDWLKAVVPIIPMFIVIGWSGGVMYYLDIE
EEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEEEEEE
YTPMTATLGALILGVGSEYAILMMERYFEEKDAGATPMEAIHMTSAKIGTAIIASGATTV
ECCHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCHHHH
FGFLALVVSPFPMISNFGIVTVVDVLMALLATFVVFPPLIVVLDTWREKRRGATAEKEAK
HHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
KQIQGADV
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; silver [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + silver [Cytoplasm] = Proton [Cytoplasm] + silver [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]