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The map label for this gene is moaB [H]

Identifier: 21227580

GI number: 21227580

Start: 1761355

End: 1761894

Strand: Direct

Name: moaB [H]

Synonym: MM_1478

Alternate gene names: 21227580

Gene position: 1761355-1761894 (Clockwise)

Preceding gene: 21227575

Following gene: 21227581

Centisome position: 43.0

GC content: 43.7

Gene sequence:

>540_bases
ATGAAAGAATCTACACCCGAAATTCACAAAAAAGATGCCAAAAAATCTTTTTCTTTCGCTTTAATCACAATTTCAACCTC
AAGGTACGAGAAATACGGAAATCCGGCTTCTCCTGATGATGCAGAAGATCTTTCGGGAAAAGTTATGAAAGAACTTATTG
AGGCGGCAGGAAACAGAGTCTCTTTCTACAGGCTTGTCCCTGACGAAAAAGATTCACTTCTGGATGCCATTTTTTTCGCG
CTTGAAAGTTCTGCAGACATCGTTATAACAAGCGGAGGCACGGGACTTGCTCCGAAAGACCTTACAATCGAGTCCATAGC
CCCTCTTTTTGAAAAAGACATCCCTGGTTTCGGGGAACTTTTCAGGTACAAGAGCCTTGAAGAAATTGGCACGTCGGTAA
TTCTGACCAGAGCTTCAGCAGGCGTGATTAAAGGAAAAGCTGTATTCTGCCTGCCGGGGTCGCCAAATGCTGTGAAGCTT
GCCCTTTCTAAAATTATCATTCCCGAAGCCGGGCATATTGTCAGGCATGTTAGAGAATAA

Upstream 100 bases:

>100_bases
AAATTACACGAAAACTGTAATATAAATATAATATCGTAGGAACTTAACAGAAAACTCAGAGGAAGAGAATAATCTTAATA
TATCGGAGAGTGCCGTTTTC

Downstream 100 bases:

>100_bases
AACTGATAAGTGAAGATGATAGGATTTTGTAAAGAAATGAGCTTGAAAAAATAGCGATCTAAATACTGACTGCGAAATCT
CAAAAATCATTTCTCTTCAT

Product: molybdenum cofactor biosynthesis protein B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MKESTPEIHKKDAKKSFSFALITISTSRYEKYGNPASPDDAEDLSGKVMKELIEAAGNRVSFYRLVPDEKDSLLDAIFFA
LESSADIVITSGGTGLAPKDLTIESIAPLFEKDIPGFGELFRYKSLEEIGTSVILTRASAGVIKGKAVFCLPGSPNAVKL
ALSKIIIPEAGHIVRHVRE

Sequences:

>Translated_179_residues
MKESTPEIHKKDAKKSFSFALITISTSRYEKYGNPASPDDAEDLSGKVMKELIEAAGNRVSFYRLVPDEKDSLLDAIFFA
LESSADIVITSGGTGLAPKDLTIESIAPLFEKDIPGFGELFRYKSLEEIGTSVILTRASAGVIKGKAVFCLPGSPNAVKL
ALSKIIIPEAGHIVRHVRE
>Mature_179_residues
MKESTPEIHKKDAKKSFSFALITISTSRYEKYGNPASPDDAEDLSGKVMKELIEAAGNRVSFYRLVPDEKDSLLDAIFFA
LESSADIVITSGGTGLAPKDLTIESIAPLFEKDIPGFGELFRYKSLEEIGTSVILTRASAGVIKGKAVFCLPGSPNAVKL
ALSKIIIPEAGHIVRHVRE

Specific function: Maybe involved in the biosynthesis of molybdopterin [H]

COG id: COG0521

COG function: function code H; Molybdopterin biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaB/mog family [H]

Homologues:

Organism=Escherichia coli, GI1787000, Length=151, Percent_Identity=33.7748344370861, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI1786190, Length=116, Percent_Identity=37.0689655172414, Blast_Score=65, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17136978, Length=166, Percent_Identity=30.7228915662651, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24638841, Length=166, Percent_Identity=30.7228915662651, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020817
- InterPro:   IPR012245
- InterPro:   IPR008284
- InterPro:   IPR001453 [H]

Pfam domain/function: PF00994 MoCF_biosynth [H]

EC number: NA

Molecular weight: Translated: 19369; Mature: 19369

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKESTPEIHKKDAKKSFSFALITISTSRYEKYGNPASPDDAEDLSGKVMKELIEAAGNRV
CCCCCCHHHHHHHHCCEEEEEEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
SFYRLVPDEKDSLLDAIFFALESSADIVITSGGTGLAPKDLTIESIAPLFEKDIPGFGEL
EEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHH
FRYKSLEEIGTSVILTRASAGVIKGKAVFCLPGSPNAVKLALSKIIIPEAGHIVRHVRE
HHHHCHHHHCCEEEEEECCCCEEECCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHCC
>Mature Secondary Structure
MKESTPEIHKKDAKKSFSFALITISTSRYEKYGNPASPDDAEDLSGKVMKELIEAAGNRV
CCCCCCHHHHHHHHCCEEEEEEEEECHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCEE
SFYRLVPDEKDSLLDAIFFALESSADIVITSGGTGLAPKDLTIESIAPLFEKDIPGFGEL
EEEEECCCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHCCCCHHHH
FRYKSLEEIGTSVILTRASAGVIKGKAVFCLPGSPNAVKLALSKIIIPEAGHIVRHVRE
HHHHCHHHHCCEEEEEECCCCEEECCEEEEECCCCCHHHHHHHHHHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin precursor biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9387221; 9384377 [H]