Click here to switch to the map view.

The map label for this gene is pqqE [H]

Identifier: 21227576

GI number: 21227576

Start: 1756839

End: 1758053

Strand: Reverse

Name: pqqE [H]

Synonym: MM_1474

Alternate gene names: 21227576

Gene position: 1758053-1756839 (Counterclockwise)

Preceding gene: 21227577

Following gene: 21227573

Centisome position: 42.92

GC content: 45.6

Gene sequence:

>1215_bases
ATGACTCCTGAAAAAAAGAATGTGCCGGACTTCCCCACAAAAAATAAGAATATAGAAATTTTCTCCATGCCAGGGCTGTC
TGTAAACCTTCAGCAGCGTGAAGGAATGACCGTAAAACTTACGGCACAGGGGACTCTGAAATCCGCCTGTATCCCTGTAC
TGAAAAAGATGAACTCACGCTTACAGGAAGAGAAACCGGCACTTGTACAGGAAGACAGCTTCATTCCCTCAGCCTGGCTT
CCTCCCATACCCGGACCTGCTTTTAAACGGCTTATTTTCGCAGAAGTCCAGATAGCTCTGGGAAAATATATTCCTGAAAC
CGTTACCATTGAAATTACCCGCCAGAACAGTTCAAGGTACCCCCCAGGAGCGGTCGCTGACGAACTGGATACAGACACAA
TTAAAAGAGTAATAGATGAAGCGCTGGACCTTGGCACATTAATTATCAGTTTTACCGAGAATGACCCCCTGCTGAGGGAA
GAGATCTTTGAACTTATTGAATATGTGGACAAAAAACGCGCTATAGTTAACTGTTCTACATGGGGTACGGACTTCACAAA
AGAAACTGCTCTCCGTTTGAAAAAAGCCGGACTTCACTCCCTCATGGTCGGCGTTTATTCGACTGACCCCCAGAAGCATG
ATGCGGTCCGAAAATCCGAAGGCTCGTACGATCGGGCGATATCAACCATAAAACTGGCTCTTGAAGCAGGGCTTCTGGTT
GTTATGACAACTCACGCCTCTCCTTCAAACATGAAAGAACTTCCCGCTCTCTATGCACTTGCATCGGAACTTGGGGTTCA
TGAATTTTCAGTCTGGGAATCAATGCCGAAAAGAAAAGGAGAGTCTGTGATTACTGACAGAGACAGAAGAGCAATCCTTG
AAATGTATCACAGGATTAATTCTGCCCCGGAAGGCCCTCGAATGTTTTCAAATACTTATTTCGAAGGGCAGATGATGGGT
GCGATGGCAGGCAGGCGCTGGATGCATGTGACCGTAGACGGAGACGTAAAACCAAGCCCTTATCCCCCATTCAGGTTCGG
AAATGTTAAAGAAGTACCCTTAAAAGAAATCTGGCAGAGGATCAGAAGTTATCCTTATTTCCAGAGGCAGAAAAACCTCA
GTCCCATGCACGACCCTGAGTTTATGGAATTTGTCGATAAAATTCCAGAGGAGGCAAAACTGCCCTATCCTTTTGAAAAG
ATTTGCGAGAAATAA

Upstream 100 bases:

>100_bases
GATATTTAGAGGATATTTAAGAGATAGACTTAAAATATAGATTATTTTAGGTTTTGTCAGTTAAATCAGAAAAACCGTAC
GAAATTAGATGTGAGGAAAA

Downstream 100 bases:

>100_bases
TCTGAAGGTTGTCTGCTGTATGAACTTTTATTTATGAAAGTTTTCTTTGCATTTTGATGCGCTTCAGCTTAAAATTCATT
CAGTAGATAAATCCTGAGCT

Product: metallo cofactor biosynthesis protein

Products: NA

Alternate protein names: Pyrroloquinoline quinone biosynthesis protein E [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MTPEKKNVPDFPTKNKNIEIFSMPGLSVNLQQREGMTVKLTAQGTLKSACIPVLKKMNSRLQEEKPALVQEDSFIPSAWL
PPIPGPAFKRLIFAEVQIALGKYIPETVTIEITRQNSSRYPPGAVADELDTDTIKRVIDEALDLGTLIISFTENDPLLRE
EIFELIEYVDKKRAIVNCSTWGTDFTKETALRLKKAGLHSLMVGVYSTDPQKHDAVRKSEGSYDRAISTIKLALEAGLLV
VMTTHASPSNMKELPALYALASELGVHEFSVWESMPKRKGESVITDRDRRAILEMYHRINSAPEGPRMFSNTYFEGQMMG
AMAGRRWMHVTVDGDVKPSPYPPFRFGNVKEVPLKEIWQRIRSYPYFQRQKNLSPMHDPEFMEFVDKIPEEAKLPYPFEK
ICEK

Sequences:

>Translated_404_residues
MTPEKKNVPDFPTKNKNIEIFSMPGLSVNLQQREGMTVKLTAQGTLKSACIPVLKKMNSRLQEEKPALVQEDSFIPSAWL
PPIPGPAFKRLIFAEVQIALGKYIPETVTIEITRQNSSRYPPGAVADELDTDTIKRVIDEALDLGTLIISFTENDPLLRE
EIFELIEYVDKKRAIVNCSTWGTDFTKETALRLKKAGLHSLMVGVYSTDPQKHDAVRKSEGSYDRAISTIKLALEAGLLV
VMTTHASPSNMKELPALYALASELGVHEFSVWESMPKRKGESVITDRDRRAILEMYHRINSAPEGPRMFSNTYFEGQMMG
AMAGRRWMHVTVDGDVKPSPYPPFRFGNVKEVPLKEIWQRIRSYPYFQRQKNLSPMHDPEFMEFVDKIPEEAKLPYPFEK
ICEK
>Mature_403_residues
TPEKKNVPDFPTKNKNIEIFSMPGLSVNLQQREGMTVKLTAQGTLKSACIPVLKKMNSRLQEEKPALVQEDSFIPSAWLP
PIPGPAFKRLIFAEVQIALGKYIPETVTIEITRQNSSRYPPGAVADELDTDTIKRVIDEALDLGTLIISFTENDPLLREE
IFELIEYVDKKRAIVNCSTWGTDFTKETALRLKKAGLHSLMVGVYSTDPQKHDAVRKSEGSYDRAISTIKLALEAGLLVV
MTTHASPSNMKELPALYALASELGVHEFSVWESMPKRKGESVITDRDRRAILEMYHRINSAPEGPRMFSNTYFEGQMMGA
MAGRRWMHVTVDGDVKPSPYPPFRFGNVKEVPLKEIWQRIRSYPYFQRQKNLSPMHDPEFMEFVDKIPEEAKLPYPFEKI
CEK

Specific function: Unknown

COG id: COG0535

COG function: function code R; Predicted Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the radical SAM superfamily. PqqE family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006638
- InterPro:   IPR000385
- InterPro:   IPR017200
- InterPro:   IPR011843
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: NA

Molecular weight: Translated: 45912; Mature: 45780

Theoretical pI: Translated: 7.62; Mature: 7.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEKKNVPDFPTKNKNIEIFSMPGLSVNLQQREGMTVKLTAQGTLKSACIPVLKKMNSR
CCCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHH
LQEEKPALVQEDSFIPSAWLPPIPGPAFKRLIFAEVQIALGKYIPETVTIEITRQNSSRY
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PPGAVADELDTDTIKRVIDEALDLGTLIISFTENDPLLREEIFELIEYVDKKRAIVNCST
CCCCHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECC
WGTDFTKETALRLKKAGLHSLMVGVYSTDPQKHDAVRKSEGSYDRAISTIKLALEAGLLV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCEEE
VMTTHASPSNMKELPALYALASELGVHEFSVWESMPKRKGESVITDRDRRAILEMYHRIN
EEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
SAPEGPRMFSNTYFEGQMMGAMAGRRWMHVTVDGDVKPSPYPPFRFGNVKEVPLKEIWQR
CCCCCCHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHH
IRSYPYFQRQKNLSPMHDPEFMEFVDKIPEEAKLPYPFEKICEK
HHCCCCHHHHCCCCCCCCHHHHHHHHHCCHHCCCCCCHHHHHCC
>Mature Secondary Structure 
TPEKKNVPDFPTKNKNIEIFSMPGLSVNLQQREGMTVKLTAQGTLKSACIPVLKKMNSR
CCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEEEEEECCCHHHHHHHHHHHHHHH
LQEEKPALVQEDSFIPSAWLPPIPGPAFKRLIFAEVQIALGKYIPETVTIEITRQNSSRY
HHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCC
PPGAVADELDTDTIKRVIDEALDLGTLIISFTENDPLLREEIFELIEYVDKKRAIVNCST
CCCCHHHHCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECC
WGTDFTKETALRLKKAGLHSLMVGVYSTDPQKHDAVRKSEGSYDRAISTIKLALEAGLLV
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHCCEEE
VMTTHASPSNMKELPALYALASELGVHEFSVWESMPKRKGESVITDRDRRAILEMYHRIN
EEEECCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHC
SAPEGPRMFSNTYFEGQMMGAMAGRRWMHVTVDGDVKPSPYPPFRFGNVKEVPLKEIWQR
CCCCCCHHHCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHH
IRSYPYFQRQKNLSPMHDPEFMEFVDKIPEEAKLPYPFEKICEK
HHCCCCHHHHCCCCCCCCHHHHHHHHHCCHHCCCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11111029 [H]