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The map label for this gene is radB [H]

Identifier: 21227471

GI number: 21227471

Start: 1639456

End: 1640202

Strand: Direct

Name: radB [H]

Synonym: MM_1369

Alternate gene names: 21227471

Gene position: 1639456-1640202 (Clockwise)

Preceding gene: 21227465

Following gene: 21227473

Centisome position: 40.02

GC content: 45.52

Gene sequence:

>747_bases
ATGACAAAAAATTACAAAAAAAACATTATATCATTGGTCTTTCATACCTCTCTCAAGTGTAAAAAGAGGTGTCACGTCAT
AGAGAAACTATTATCTTCCGGTTGTAAACCCCTTGATGAGCTTCTGGGGGGAGGTTTCGAGAGAGGAATCGTAACCCAGG
TTTTCGGAGCAGCAGGAACCGGAAAAACAAATATTTGTATCCAGCTTGCAGTGGAATGTGTAAAGCAGGGACAGAAAGTC
ATTTTCATCGATACTGAAGGGCTTTCTCCTGTTCGTTTCAAGCAGATCGCAGGAGAAAATGCAAAGGAAATAGCCAGGAG
CATAATTATCTATGAGCCTCTCAGCTTCGAAGAGCAATATTCATCCGTAAGAGAGGTCGAAAGGATAGCAGGCGAAAATG
TCGGGCTCGTAGTCCTGGACTCCGCAACTTCGTATTACAGGTATGAGCTGGAGGATGACGAGACCGGAATAAAAAGCCGG
AGAGAGCTTGCTAACCAGATAGGGTTCTTACATGCTCTTGCCCGAAAACATGGTTTTGCCGCACTTATAACAAATCAGGT
ATATTCGGATGTTGTCGGAGGAGGAGTGCGCCCGCTGGGAGGAAGTTCCCTTGAGCATATCTCAAAAACGATTATCCGGC
TGGAAAAAACGGGCGAGGGTACAAGGCGTGCCGTTCTTTACAAACACCGCTCCCGACCTGAAGGCTCAAGTGCGGAATTT
ACAATTACAGCAGAAGGGATTCGTTAA

Upstream 100 bases:

>100_bases
TATATTGATAAATGACTTCGTATTTCTCTTCTATTTTTCTCTTTCATTTCTTTCTGCTTCTTTTTACTTTTTTCATACTC
TGGAGCTCTCTTTTCAGAAA

Downstream 100 bases:

>100_bases
AAAAATATCTCATAACAGAAAAACGTAAAGCTCCCGGAAAAATCCGGGATTCTGGCATCACTGTTTTTGCAGTAACTTCT
CTCCTTAAGGGTTTTTCCCG

Product: DNA repair and recombination protein RadB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 247

Protein sequence:

>248_residues
MTKNYKKNIISLVFHTSLKCKKRCHVIEKLLSSGCKPLDELLGGGFERGIVTQVFGAAGTGKTNICIQLAVECVKQGQKV
IFIDTEGLSPVRFKQIAGENAKEIARSIIIYEPLSFEEQYSSVREVERIAGENVGLVVLDSATSYYRYELEDDETGIKSR
RELANQIGFLHALARKHGFAALITNQVYSDVVGGGVRPLGGSSLEHISKTIIRLEKTGEGTRRAVLYKHRSRPEGSSAEF
TITAEGIR

Sequences:

>Translated_248_residues
MTKNYKKNIISLVFHTSLKCKKRCHVIEKLLSSGCKPLDELLGGGFERGIVTQVFGAAGTGKTNICIQLAVECVKQGQKV
IFIDTEGLSPVRFKQIAGENAKEIARSIIIYEPLSFEEQYSSVREVERIAGENVGLVVLDSATSYYRYELEDDETGIKSR
RELANQIGFLHALARKHGFAALITNQVYSDVVGGGVRPLGGSSLEHISKTIIRLEKTGEGTRRAVLYKHRSRPEGSSAEF
TITAEGIR
>Mature_247_residues
TKNYKKNIISLVFHTSLKCKKRCHVIEKLLSSGCKPLDELLGGGFERGIVTQVFGAAGTGKTNICIQLAVECVKQGQKVI
FIDTEGLSPVRFKQIAGENAKEIARSIIIYEPLSFEEQYSSVREVERIAGENVGLVVLDSATSYYRYELEDDETGIKSRR
ELANQIGFLHALARKHGFAALITNQVYSDVVGGGVRPLGGSSLEHISKTIIRLEKTGEGTRRAVLYKHRSRPEGSSAEFT
ITAEGIR

Specific function: Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange [H]

COG id: COG0468

COG function: function code L; RecA/RadA recombinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eukaryotic recA-like protein family. RadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI19924133, Length=257, Percent_Identity=30.7392996108949, Blast_Score=98, Evalue=8e-21,
Organism=Homo sapiens, GI256017143, Length=221, Percent_Identity=31.2217194570136, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI256017141, Length=221, Percent_Identity=31.2217194570136, Blast_Score=85, Evalue=7e-17,
Organism=Homo sapiens, GI23238219, Length=236, Percent_Identity=28.8135593220339, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI256017145, Length=153, Percent_Identity=30.718954248366, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71997295, Length=247, Percent_Identity=30.3643724696356, Blast_Score=90, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71997301, Length=247, Percent_Identity=30.3643724696356, Blast_Score=90, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6321027, Length=226, Percent_Identity=34.9557522123894, Blast_Score=77, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6320942, Length=236, Percent_Identity=32.2033898305085, Blast_Score=71, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17864108, Length=250, Percent_Identity=34, Blast_Score=93, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24651285, Length=250, Percent_Identity=34, Blast_Score=93, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013632
- InterPro:   IPR011939
- InterPro:   IPR020588
- InterPro:   IPR004504 [H]

Pfam domain/function: PF08423 Rad51 [H]

EC number: NA

Molecular weight: Translated: 27334; Mature: 27203

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKNYKKNIISLVFHTSLKCKKRCHVIEKLLSSGCKPLDELLGGGFERGIVTQVFGAAGT
CCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHCCCCC
GKTNICIQLAVECVKQGQKVIFIDTEGLSPVRFKQIAGENAKEIARSIIIYEPLSFEEQY
CCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHEECCCCHHHHH
SSVREVERIAGENVGLVVLDSATSYYRYELEDDETGIKSRRELANQIGFLHALARKHGFA
HHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
ALITNQVYSDVVGGGVRPLGGSSLEHISKTIIRLEKTGEGTRRAVLYKHRSRPEGSSAEF
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCEE
TITAEGIR
EEEECCCC
>Mature Secondary Structure 
TKNYKKNIISLVFHTSLKCKKRCHVIEKLLSSGCKPLDELLGGGFERGIVTQVFGAAGT
CCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHCCCCC
GKTNICIQLAVECVKQGQKVIFIDTEGLSPVRFKQIAGENAKEIARSIIIYEPLSFEEQY
CCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHCCCCHHHHHHHHHEECCCCHHHHH
SSVREVERIAGENVGLVVLDSATSYYRYELEDDETGIKSRRELANQIGFLHALARKHGFA
HHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHH
ALITNQVYSDVVGGGVRPLGGSSLEHISKTIIRLEKTGEGTRRAVLYKHRSRPEGSSAEF
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCEE
TITAEGIR
EEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA