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The map label for this gene is mptA [H]

Identifier: 21227324

GI number: 21227324

Start: 1447990

End: 1448946

Strand: Direct

Name: mptA [H]

Synonym: MM_1222

Alternate gene names: 21227324

Gene position: 1447990-1448946 (Clockwise)

Preceding gene: 21227321

Following gene: 21227325

Centisome position: 35.35

GC content: 45.35

Gene sequence:

>957_bases
ATGGAAAAGTGTACTTTCAACCTCCCGGATGTCCAGGCCAGCAAACCAAGCATAGCTATCAATCTCACCCGTGTTGGGGT
AACAAACATGAAAAAGCTGGTTGAAATCAAAAGAAAGGACAAACGCCCAATAGTATTGATTTCAACTTTTGATGTATTTG
TTGACCTGCCCTCGGACCGTAAAGGAGCAAACCTTTCAAGGAACTTTGAAGCTGTAGATGAGGTTCTGGAGAAGGTTCTC
AGCACACCGGTATATGAAATAGAACAGTTATGCAGCGACATTGCACATAACCTGCTTGGCCGCCATGAATATGCAAATCA
GGCTGAAGTCAGGATGAAGAGCGAATACATGATCAGGCGCGCCTCTCCCTCAACCGGAATCAAGTGCCAGGAAGTAGTTA
ATATCTTTGCCGAGGCTTCGGCTGTCAGGGGCAACGGCGATAGAGATTACTTTGATGTGAAAAAACTCATAGGCGCTGAA
GTTGTGGGAATGACTGCATGCCCCTGCGCCCAGGAGATCATGAGAGATAAAGCTGCAACCGAACTCGCCAATCTCGGGGT
TGAAAGGGACAAGATTATAAAGTTCCTGGAAAAAGTCCCCATGGCTACCCATAACCAGCGTGGCAGAGGCATAATTTCAA
TTAAAGTAGCTCATGATTTTGACGTTTCCCTGGAAAGCATAATAAAAATAATTGAGCGCTCCATGAGTTCAAGCGTTTAT
GAGGTTCTGAAACGTTCGGACGAAAAAGTCGTTGTGGAAACTGCACACATGAACCCGAAATTTGTGGAAGACTGCGTAAG
AGCAATGGCAGACAACGTGGTAAAAGAATTCCCGAACCTTCCTGACAATGCAGTGATCACCATCAAACAGACCAATGAGG
AAAGCATACACAGGCACAATGCATTTGCTGAAAGGGTAGCTCTCATGGGAGAACTCAGGAAAGAAATCAGTCAGTAA

Upstream 100 bases:

>100_bases
TATGGTCACTATATTTTTCCAAATGCATAAAATAAAATTATGTGTTTATTAAGGATTTACCCTACAAAACATACTTATCT
TTTCACGGATCTGGTTAAAT

Downstream 100 bases:

>100_bases
AAAGGTTGTAACCGGTGGAGAAAGCAACCCTTACTGAAAGAAACGTCTGTTTACTGAGAAATCAGTAAACACTAAATCCT
TTTTTTGTTTTTTTAAACTT

Product: GTP cyclohydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MEKCTFNLPDVQASKPSIAINLTRVGVTNMKKLVEIKRKDKRPIVLISTFDVFVDLPSDRKGANLSRNFEAVDEVLEKVL
STPVYEIEQLCSDIAHNLLGRHEYANQAEVRMKSEYMIRRASPSTGIKCQEVVNIFAEASAVRGNGDRDYFDVKKLIGAE
VVGMTACPCAQEIMRDKAATELANLGVERDKIIKFLEKVPMATHNQRGRGIISIKVAHDFDVSLESIIKIIERSMSSSVY
EVLKRSDEKVVVETAHMNPKFVEDCVRAMADNVVKEFPNLPDNAVITIKQTNEESIHRHNAFAERVALMGELRKEISQ

Sequences:

>Translated_318_residues
MEKCTFNLPDVQASKPSIAINLTRVGVTNMKKLVEIKRKDKRPIVLISTFDVFVDLPSDRKGANLSRNFEAVDEVLEKVL
STPVYEIEQLCSDIAHNLLGRHEYANQAEVRMKSEYMIRRASPSTGIKCQEVVNIFAEASAVRGNGDRDYFDVKKLIGAE
VVGMTACPCAQEIMRDKAATELANLGVERDKIIKFLEKVPMATHNQRGRGIISIKVAHDFDVSLESIIKIIERSMSSSVY
EVLKRSDEKVVVETAHMNPKFVEDCVRAMADNVVKEFPNLPDNAVITIKQTNEESIHRHNAFAERVALMGELRKEISQ
>Mature_318_residues
MEKCTFNLPDVQASKPSIAINLTRVGVTNMKKLVEIKRKDKRPIVLISTFDVFVDLPSDRKGANLSRNFEAVDEVLEKVL
STPVYEIEQLCSDIAHNLLGRHEYANQAEVRMKSEYMIRRASPSTGIKCQEVVNIFAEASAVRGNGDRDYFDVKKLIGAE
VVGMTACPCAQEIMRDKAATELANLGVERDKIIKFLEKVPMATHNQRGRGIISIKVAHDFDVSLESIIKIIERSMSSSVY
EVLKRSDEKVVVETAHMNPKFVEDCVRAMADNVVKEFPNLPDNAVITIKQTNEESIHRHNAFAERVALMGELRKEISQ

Specific function: Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin [H]

COG id: COG1469

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP cyclohydrolase IV family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003801
- InterPro:   IPR022840
- InterPro:   IPR002042 [H]

Pfam domain/function: PF02649 DUF198 [H]

EC number: NA

Molecular weight: Translated: 35747; Mature: 35747

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKCTFNLPDVQASKPSIAINLTRVGVTNMKKLVEIKRKDKRPIVLISTFDVFVDLPSDR
CCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCC
KGANLSRNFEAVDEVLEKVLSTPVYEIEQLCSDIAHNLLGRHEYANQAEVRMKSEYMIRR
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEE
ASPSTGIKCQEVVNIFAEASAVRGNGDRDYFDVKKLIGAEVVGMTACPCAQEIMRDKAAT
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ELANLGVERDKIIKFLEKVPMATHNQRGRGIISIKVAHDFDVSLESIIKIIERSMSSSVY
HHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EVLKRSDEKVVVETAHMNPKFVEDCVRAMADNVVKEFPNLPDNAVITIKQTNEESIHRHN
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHH
AFAERVALMGELRKEISQ
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKCTFNLPDVQASKPSIAINLTRVGVTNMKKLVEIKRKDKRPIVLISTFDVFVDLPSDR
CCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCCCC
KGANLSRNFEAVDEVLEKVLSTPVYEIEQLCSDIAHNLLGRHEYANQAEVRMKSEYMIRR
CCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHEE
ASPSTGIKCQEVVNIFAEASAVRGNGDRDYFDVKKLIGAEVVGMTACPCAQEIMRDKAAT
CCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
ELANLGVERDKIIKFLEKVPMATHNQRGRGIISIKVAHDFDVSLESIIKIIERSMSSSVY
HHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHH
EVLKRSDEKVVVETAHMNPKFVEDCVRAMADNVVKEFPNLPDNAVITIKQTNEESIHRHN
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHH
AFAERVALMGELRKEISQ
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA