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The map label for this gene is hyuA [H]

Identifier: 21227179

GI number: 21227179

Start: 1266832

End: 1268847

Strand: Direct

Name: hyuA [H]

Synonym: MM_1077

Alternate gene names: 21227179

Gene position: 1266832-1268847 (Clockwise)

Preceding gene: 21227178

Following gene: 21227180

Centisome position: 30.93

GC content: 46.58

Gene sequence:

>2016_bases
ATGCACTTCAGTCTTGGAATTGATGCAGGGGGCACATATACCGATGCCGTTATCGTGAGGGATTCGGACGGAGCAGTGGT
TGAGTCAAGCAAAGCTCTGACAACCTACCCCGACCCTCTGCCTGGAATGAAAAATGCAATTGACAAACTGGATCCGGGAT
ACCTTGGAGATATAAAGCTGGTATCAGTATCCACCACACTATCCACAAATACGATTCTGGAAAGCACGGGATTTCCTGTA
GGGCTTATTATGGTGGGGGACTATGTGATCCCTGAGAAACTTCCCACTGATTACTGGATAGCAGTTTCAGGCGGGCATAA
CAGCGATGGAGAAGAATTAAAAGCCCTGAACCTTGATGCAGTAGAAGAATTCGCACTCAAAGTACAGAGTAAAGTTTCCG
CTTTTGCAGTTTCTTCTTATTTCAGCAACCGGAACCCTGAACATGAGCTTGCAGTTAAAAAAGCCTTAAAGGAACTTACC
GGACTGCCGGTTGTTTGCGGGCATGAACTATCCCAGGATCTCGGAGCCTATGAAAGGGCTGTAACTGCTTTTCTGAATGC
CCAGCTGATCCCTATTACTCATAAGTTCATCCAGGCAATAATTGAAGAATTCGAAAGTCGCGGAATCAACGCAAACATGC
TGATGCTGAAATGCGATGGGTCAGTGGTCGGGATAGAAGAGGCTCTGGAAAAACCCATTGAAACTATTTTCTCGGGCCCA
GCAGCAAGTCTTGTTGGAGCCTCACACCTTACCAGGCTTGATACATGTGCCGTAATCGATGTAGGAGGGACGAGTACGGA
TGTTGCCATGATGCAGAACGGGCTTCCGGAACTCAGCAGCTCGGGCGCGGTGGTTGGAGGCTGGCAGACCCGTGTAAAAG
CTATCCGCATGGAGACCTCAGCGACCGGAGGTGACAGCCATATCTGGCTCAAGGGAGATAGGATCAATGTGGGACCCCGA
AGAGTCATTCCTCTCTGCAGGGCTTCTGCTATATATCCGGGATTCAGGGAGAAGCTCAAGCATAACAGGGTAGCAAAAGG
TTACCTCTGTGAAAATATCCAGGTAACGAAGTTTTTTGTCAGGACAGGGTTCAGACCTATAGAGTTAAAAGCAGGGGAAA
GGGAAATTTACAGGAATATAGGAAAAGATCCTGTTTCTTTCGGAGACCTGCTCATAGCCCTGAAAAAACGCCCTTCGCCT
TCAATACTTGATTCTCTTATACAGAAAAGGCTTATTCAGGCTATAGGCTTTACACCTACCGATGCCCTGCACGTCCTGAG
TGAGTATACGGAATGGGATGTTGAAGCTGCAAGGATAGGAGCTTACTTACTTGGGAGACCACTTAAACTGGACCCTGAAG
ATTTCAGTGCAGAAGTAAAGCGCAGGGTTGCACGTAATATTGCAGAAGACCTCATCGCATATATGATAGAAGGAATGCCC
AGAGAAGAGATTGACAGAGTGCTCAAGGGAAAGAACTTTACTCGTTTCAGAGTAGAAATTCCTGTCGTTCTTCTCGGAGG
TCCTGTGGGAGCATATGTAGAAGACATGAGAAAGCTGATCAGCGCCGAGTTTATAGTTCCAGAACACGCTGATGTCGGTA
ATGCAGTTGGGGCTCTTGTCGGAAAAGGAATTAAGAGGGTGGAGATTCTCATAAAAACAAGGTTCATCCCCAAATCCAGA
GAAGAGACGCCTGAAGGTGAGGAACACTGTGCAGCGCCGGAGAGTGAAGTTATAGAAGATACACTCCAGCAGCAGGAAAA
GAAAACCGAGTTCATTGTCTTTTCACCATCGGAAAGGAAAAAATTTGAAGTATATTCCGAAGCTCTCGAATATGCCGAAA
AACTTGGAAAGCAGCTTGTTATGGATTATATGATCAATGCAGGTCTTGGGAAAGAAGATATAAGAATAGACGTAAGCAGA
AAACATCTGTCACCAAGCGGCTGGACGGATGTCCCTCTGGAGACAAAACTTGTTTATGTAGGGATAGGAATCCCGAAGAA
TAGTGTGATTGCCTGA

Upstream 100 bases:

>100_bases
ATTCTCGATAACCGGCCTGCCATAGGAAAGAATGACCGGAATACTTTCTGGAAAGCCTTAAGAAGCTACTATCCAATTCA
TAAAAGAGGTTAATGAAGAA

Downstream 100 bases:

>100_bases
GGGAAGTAAGAAGTAACGGAAATGTCGAACAATATAAGTAAAAATATATATCTTGAGGCATAACTTTATAAATCCGGCTA
AAAGGGATTAATATAGTTAA

Product: hypothetical protein

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MHFSLGIDAGGTYTDAVIVRDSDGAVVESSKALTTYPDPLPGMKNAIDKLDPGYLGDIKLVSVSTTLSTNTILESTGFPV
GLIMVGDYVIPEKLPTDYWIAVSGGHNSDGEELKALNLDAVEEFALKVQSKVSAFAVSSYFSNRNPEHELAVKKALKELT
GLPVVCGHELSQDLGAYERAVTAFLNAQLIPITHKFIQAIIEEFESRGINANMLMLKCDGSVVGIEEALEKPIETIFSGP
AASLVGASHLTRLDTCAVIDVGGTSTDVAMMQNGLPELSSSGAVVGGWQTRVKAIRMETSATGGDSHIWLKGDRINVGPR
RVIPLCRASAIYPGFREKLKHNRVAKGYLCENIQVTKFFVRTGFRPIELKAGEREIYRNIGKDPVSFGDLLIALKKRPSP
SILDSLIQKRLIQAIGFTPTDALHVLSEYTEWDVEAARIGAYLLGRPLKLDPEDFSAEVKRRVARNIAEDLIAYMIEGMP
REEIDRVLKGKNFTRFRVEIPVVLLGGPVGAYVEDMRKLISAEFIVPEHADVGNAVGALVGKGIKRVEILIKTRFIPKSR
EETPEGEEHCAAPESEVIEDTLQQQEKKTEFIVFSPSERKKFEVYSEALEYAEKLGKQLVMDYMINAGLGKEDIRIDVSR
KHLSPSGWTDVPLETKLVYVGIGIPKNSVIA

Sequences:

>Translated_671_residues
MHFSLGIDAGGTYTDAVIVRDSDGAVVESSKALTTYPDPLPGMKNAIDKLDPGYLGDIKLVSVSTTLSTNTILESTGFPV
GLIMVGDYVIPEKLPTDYWIAVSGGHNSDGEELKALNLDAVEEFALKVQSKVSAFAVSSYFSNRNPEHELAVKKALKELT
GLPVVCGHELSQDLGAYERAVTAFLNAQLIPITHKFIQAIIEEFESRGINANMLMLKCDGSVVGIEEALEKPIETIFSGP
AASLVGASHLTRLDTCAVIDVGGTSTDVAMMQNGLPELSSSGAVVGGWQTRVKAIRMETSATGGDSHIWLKGDRINVGPR
RVIPLCRASAIYPGFREKLKHNRVAKGYLCENIQVTKFFVRTGFRPIELKAGEREIYRNIGKDPVSFGDLLIALKKRPSP
SILDSLIQKRLIQAIGFTPTDALHVLSEYTEWDVEAARIGAYLLGRPLKLDPEDFSAEVKRRVARNIAEDLIAYMIEGMP
REEIDRVLKGKNFTRFRVEIPVVLLGGPVGAYVEDMRKLISAEFIVPEHADVGNAVGALVGKGIKRVEILIKTRFIPKSR
EETPEGEEHCAAPESEVIEDTLQQQEKKTEFIVFSPSERKKFEVYSEALEYAEKLGKQLVMDYMINAGLGKEDIRIDVSR
KHLSPSGWTDVPLETKLVYVGIGIPKNSVIA
>Mature_671_residues
MHFSLGIDAGGTYTDAVIVRDSDGAVVESSKALTTYPDPLPGMKNAIDKLDPGYLGDIKLVSVSTTLSTNTILESTGFPV
GLIMVGDYVIPEKLPTDYWIAVSGGHNSDGEELKALNLDAVEEFALKVQSKVSAFAVSSYFSNRNPEHELAVKKALKELT
GLPVVCGHELSQDLGAYERAVTAFLNAQLIPITHKFIQAIIEEFESRGINANMLMLKCDGSVVGIEEALEKPIETIFSGP
AASLVGASHLTRLDTCAVIDVGGTSTDVAMMQNGLPELSSSGAVVGGWQTRVKAIRMETSATGGDSHIWLKGDRINVGPR
RVIPLCRASAIYPGFREKLKHNRVAKGYLCENIQVTKFFVRTGFRPIELKAGEREIYRNIGKDPVSFGDLLIALKKRPSP
SILDSLIQKRLIQAIGFTPTDALHVLSEYTEWDVEAARIGAYLLGRPLKLDPEDFSAEVKRRVARNIAEDLIAYMIEGMP
REEIDRVLKGKNFTRFRVEIPVVLLGGPVGAYVEDMRKLISAEFIVPEHADVGNAVGALVGKGIKRVEILIKTRFIPKSR
EETPEGEEHCAAPESEVIEDTLQQQEKKTEFIVFSPSERKKFEVYSEALEYAEKLGKQLVMDYMINAGLGKEDIRIDVSR
KHLSPSGWTDVPLETKLVYVGIGIPKNSVIA

Specific function: HyuA and hyuB convert D- and L-substituted hydantoins to corresponding N-carbamyl-amino acids [H]

COG id: COG0145

COG function: function code EQ; N-methylhydantoinase A/acetone carboxylase, beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the oxoprolinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008040
- InterPro:   IPR002821 [H]

Pfam domain/function: PF05378 Hydant_A_N; PF01968 Hydantoinase_A [H]

EC number: NA

Molecular weight: Translated: 73552; Mature: 73552

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHFSLGIDAGGTYTDAVIVRDSDGAVVESSKALTTYPDPLPGMKNAIDKLDPGYLGDIKL
CEEEEECCCCCCEEEEEEEECCCCCEEECCCCEEECCCCCCCHHHHHHHCCCCCCCCEEE
VSVSTTLSTNTILESTGFPVGLIMVGDYVIPEKLPTDYWIAVSGGHNSDGEELKALNLDA
EEEEEECCCCCEECCCCCCEEEEEECCEECCCCCCCCEEEEEECCCCCCCHHHEECCHHH
VEEFALKVQSKVSAFAVSSYFSNRNPEHELAVKKALKELTGLPVVCGHELSQDLGAYERA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHH
VTAFLNAQLIPITHKFIQAIIEEFESRGINANMLMLKCDGSVVGIEEALEKPIETIFSGP
HHHHHCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEECHHHHHHHHHHHHHCCC
AASLVGASHLTRLDTCAVIDVGGTSTDVAMMQNGLPELSSSGAVVGGWQTRVKAIRMETS
HHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCCCCCCCEEECHHHHEEEEEEECC
ATGGDSHIWLKGDRINVGPRRVIPLCRASAIYPGFREKLKHNRVAKGYLCENIQVTKFFV
CCCCCCEEEEECCEECCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEECCCCEEHHHH
RTGFRPIELKAGEREIYRNIGKDPVSFGDLLIALKKRPSPSILDSLIQKRLIQAIGFTPT
HCCCCEEEECCCHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCH
DALHVLSEYTEWDVEAARIGAYLLGRPLKLDPEDFSAEVKRRVARNIAEDLIAYMIEGMP
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
REEIDRVLKGKNFTRFRVEIPVVLLGGPVGAYVEDMRKLISAEFIVPEHADVGNAVGALV
HHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH
GKGIKRVEILIKTRFIPKSREETPEGEEHCAAPESEVIEDTLQQQEKKTEFIVFSPSERK
HCCHHHEEEEEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCH
KFEVYSEALEYAEKLGKQLVMDYMINAGLGKEDIRIDVSRKHLSPSGWTDVPLETKLVYV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCCCEEEEEE
GIGIPKNSVIA
EECCCCCCCCC
>Mature Secondary Structure
MHFSLGIDAGGTYTDAVIVRDSDGAVVESSKALTTYPDPLPGMKNAIDKLDPGYLGDIKL
CEEEEECCCCCCEEEEEEEECCCCCEEECCCCEEECCCCCCCHHHHHHHCCCCCCCCEEE
VSVSTTLSTNTILESTGFPVGLIMVGDYVIPEKLPTDYWIAVSGGHNSDGEELKALNLDA
EEEEEECCCCCEECCCCCCEEEEEECCEECCCCCCCCEEEEEECCCCCCCHHHEECCHHH
VEEFALKVQSKVSAFAVSSYFSNRNPEHELAVKKALKELTGLPVVCGHELSQDLGAYERA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHH
VTAFLNAQLIPITHKFIQAIIEEFESRGINANMLMLKCDGSVVGIEEALEKPIETIFSGP
HHHHHCCEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEECHHHHHHHHHHHHHCCC
AASLVGASHLTRLDTCAVIDVGGTSTDVAMMQNGLPELSSSGAVVGGWQTRVKAIRMETS
HHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHCCCCCCCCCCCEEECHHHHEEEEEEECC
ATGGDSHIWLKGDRINVGPRRVIPLCRASAIYPGFREKLKHNRVAKGYLCENIQVTKFFV
CCCCCCEEEEECCEECCCCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCEECCCCEEHHHH
RTGFRPIELKAGEREIYRNIGKDPVSFGDLLIALKKRPSPSILDSLIQKRLIQAIGFTPT
HCCCCEEEECCCHHHHHHHCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCH
DALHVLSEYTEWDVEAARIGAYLLGRPLKLDPEDFSAEVKRRVARNIAEDLIAYMIEGMP
HHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
REEIDRVLKGKNFTRFRVEIPVVLLGGPVGAYVEDMRKLISAEFIVPEHADVGNAVGALV
HHHHHHHHCCCCCEEEEEEEEEEEECCCHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHH
GKGIKRVEILIKTRFIPKSREETPEGEEHCAAPESEVIEDTLQQQEKKTEFIVFSPSERK
HCCHHHEEEEEEEECCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCH
KFEVYSEALEYAEKLGKQLVMDYMINAGLGKEDIRIDVSRKHLSPSGWTDVPLETKLVYV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCCCCEEEEEE
GIGIPKNSVIA
EECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1732229 [H]