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The map label for this gene is cbiL [H]

Identifier: 21227101

GI number: 21227101

Start: 1173537

End: 1174145

Strand: Reverse

Name: cbiL [H]

Synonym: MM_0999

Alternate gene names: 21227101

Gene position: 1174145-1173537 (Counterclockwise)

Preceding gene: 21227102

Following gene: 21227100

Centisome position: 28.66

GC content: 44.01

Gene sequence:

>609_bases
ATGTTAATAGGAGTAGGACTTGGTCCCGGAGACCCCCAGCTTTTGACCCTCAAAGCAGTGAACGTTTTGAAAAACAGCGA
TAAGGTATATGTTCCAGGCCGCCTGGCAAAAGACCTTGTAGCTCCTTATGTGGATGCAGAAATCCTTGAGTTCCCCATGA
TAAGGGATATCGAAGTCCTGAACACTCTCTGGAAAGAAAATGCAGACCGTATTGCCGACGAAGCAAGAAAAGGGACAGTG
GCTTTCGGGCTTATAGGTGATCCAAACTTTTTCTCAACTTTCACTCACCTGAAAAAAGTTATGAACAGGCACTATCCGGA
TGTTGAGACCTCAACAGTGCCAGGAATAAGTTCTATCACATCTTTTGCTGCAAGGACTGATGTGGCTGTTGAGAGTTCCT
TTGAGGTCAGTGACGGCTCTGATATCGGGTATAAGATCCACCTTAAAGCCACACAGCCGAGAAAGATAATCGAACAGCTT
GAAACCGAAGGGTACAGGGAGTTTATTTTCGCAGAGAGGCTCTTTTCGGACAATGAAACGATTATCAGCAAAAAAGAAGA
TATTCCGGAAAAAGGGAACTATTTCAGCATTATTTACGGAAAGAAGTAA

Upstream 100 bases:

>100_bases
GCAATCCTGAGATTCATTCTTTAATTACCATCAGATTAAATCACCATCAAGTTCATTAATTTACTCTTAATATTTACCTG
TAAATTTATGGAGCGATAAT

Downstream 100 bases:

>100_bases
AGCTGCATGAAACAAATTTCTAGCGATAAAATGAGGTTTGAGTATTGTATAAATTGAATTTCTGTAATAATTGAACTTCT
GTAGACAATTGAAAACCTCA

Product: cobalt-precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 202; Mature: 202

Protein sequence:

>202_residues
MLIGVGLGPGDPQLLTLKAVNVLKNSDKVYVPGRLAKDLVAPYVDAEILEFPMIRDIEVLNTLWKENADRIADEARKGTV
AFGLIGDPNFFSTFTHLKKVMNRHYPDVETSTVPGISSITSFAARTDVAVESSFEVSDGSDIGYKIHLKATQPRKIIEQL
ETEGYREFIFAERLFSDNETIISKKEDIPEKGNYFSIIYGKK

Sequences:

>Translated_202_residues
MLIGVGLGPGDPQLLTLKAVNVLKNSDKVYVPGRLAKDLVAPYVDAEILEFPMIRDIEVLNTLWKENADRIADEARKGTV
AFGLIGDPNFFSTFTHLKKVMNRHYPDVETSTVPGISSITSFAARTDVAVESSFEVSDGSDIGYKIHLKATQPRKIIEQL
ETEGYREFIFAERLFSDNETIISKKEDIPEKGNYFSIIYGKK
>Mature_202_residues
MLIGVGLGPGDPQLLTLKAVNVLKNSDKVYVPGRLAKDLVAPYVDAEILEFPMIRDIEVLNTLWKENADRIADEARKGTV
AFGLIGDPNFFSTFTHLKKVMNRHYPDVETSTVPGISSITSFAARTDVAVESSFEVSDGSDIGYKIHLKATQPRKIIEQL
ETEGYREFIFAERLFSDNETIISKKEDIPEKGNYFSIIYGKK

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 22575; Mature: 22575

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00839 SUMT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIGVGLGPGDPQLLTLKAVNVLKNSDKVYVPGRLAKDLVAPYVDAEILEFPMIRDIEVL
CEEEECCCCCCCCEEEEEEHHHHCCCCEEEECHHHHHHHHHHHCCHHHHHCCCCCHHHHH
NTLWKENADRIADEARKGTVAFGLIGDPNFFSTFTHLKKVMNRHYPDVETSTVPGISSIT
HHHHHCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
SFAARTDVAVESSFEVSDGSDIGYKIHLKATQPRKIIEQLETEGYREFIFAERLFSDNET
HHHHHCCCEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCHHHHHHHHHHHHCCCCC
IISKKEDIPEKGNYFSIIYGKK
EEECCCCCCCCCCEEEEEEECC
>Mature Secondary Structure
MLIGVGLGPGDPQLLTLKAVNVLKNSDKVYVPGRLAKDLVAPYVDAEILEFPMIRDIEVL
CEEEECCCCCCCCEEEEEEHHHHCCCCEEEECHHHHHHHHHHHCCHHHHHCCCCCHHHHH
NTLWKENADRIADEARKGTVAFGLIGDPNFFSTFTHLKKVMNRHYPDVETSTVPGISSIT
HHHHHCCHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHH
SFAARTDVAVESSFEVSDGSDIGYKIHLKATQPRKIIEQLETEGYREFIFAERLFSDNET
HHHHHCCCEECCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHCHHHHHHHHHHHHCCCCC
IISKKEDIPEKGNYFSIIYGKK
EEECCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]