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The map label for this gene is trxA [H]

Identifier: 21227093

GI number: 21227093

Start: 1168022

End: 1168519

Strand: Direct

Name: trxA [H]

Synonym: MM_0991

Alternate gene names: 21227093

Gene position: 1168022-1168519 (Clockwise)

Preceding gene: 21227092

Following gene: 21227094

Centisome position: 28.51

GC content: 44.78

Gene sequence:

>498_bases
ATGAATAGGCTAGTCATATTACTGATCCTGCTTGCAGCTGTACTCTTTACAGCAGGCTGTACTGAAGACGGGGACAACTC
CACAGACGCTCAGCAAATCCAGGTAAGTGTTGTTGAAAACTTAACCGCTCTGGAACAGATTAACACATCCGTACAGGAAG
GCCCGGTCCTTATCAAATTCGGAGCTGAATGGTGTGGGCCGTGCCAGCAGATGAAACCCATCCTGAGTGACCTGGCAGCA
GAATACACCGGAAAAGCCACAGTCATGTCTGCAGACATAGATCAGAGCCGTAATCTTTCAGCTTATTTCGTAACGTCTTA
TATTCCGGATTCCTTTGTGGTTGTTGGTCTTGAAGACGGAGAGTATGTTTACATGCAGGATAACGGAAACGTCACTAAAG
ACAGATTCCAGGCAAGAGTTCTTGGGGTTATGGATAAACAGGTATACGAAGAACTCCTGGATAGAGCAATTCTTTACCAT
GAAAACGTAAATAAATAA

Upstream 100 bases:

>100_bases
GGCTTTCAGGACTATTAAAAGAAAATTATTAGTGTAACGAGAAAATCACTGATATTAAAAACCTGAAGAAATACCAAATG
AACGAATCAATGTTGAGAAC

Downstream 100 bases:

>100_bases
AAAAGCAATACAGTGAAATCTGAGTTTTAAACTTCCTCGCCAGCTGAAAATTAAATCATCAGCTGAAAATAAAACATATT
AAATGGTTAGGACTGAAAAC

Product: Thiol-disulfide isomerase/thioredoxin

Products: NA

Alternate protein names: Trx [H]

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MNRLVILLILLAAVLFTAGCTEDGDNSTDAQQIQVSVVENLTALEQINTSVQEGPVLIKFGAEWCGPCQQMKPILSDLAA
EYTGKATVMSADIDQSRNLSAYFVTSYIPDSFVVVGLEDGEYVYMQDNGNVTKDRFQARVLGVMDKQVYEELLDRAILYH
ENVNK

Sequences:

>Translated_165_residues
MNRLVILLILLAAVLFTAGCTEDGDNSTDAQQIQVSVVENLTALEQINTSVQEGPVLIKFGAEWCGPCQQMKPILSDLAA
EYTGKATVMSADIDQSRNLSAYFVTSYIPDSFVVVGLEDGEYVYMQDNGNVTKDRFQARVLGVMDKQVYEELLDRAILYH
ENVNK
>Mature_165_residues
MNRLVILLILLAAVLFTAGCTEDGDNSTDAQQIQVSVVENLTALEQINTSVQEGPVLIKFGAEWCGPCQQMKPILSDLAA
EYTGKATVMSADIDQSRNLSAYFVTSYIPDSFVVVGLEDGEYVYMQDNGNVTKDRFQARVLGVMDKQVYEELLDRAILYH
ENVNK

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

None

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 18276; Mature: 18276

Theoretical pI: Translated: 4.05; Mature: 4.05

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRLVILLILLAAVLFTAGCTEDGDNSTDAQQIQVSVVENLTALEQINTSVQEGPVLIKF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEE
GAEWCGPCQQMKPILSDLAAEYTGKATVMSADIDQSRNLSAYFVTSYIPDSFVVVGLEDG
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEECCC
EYVYMQDNGNVTKDRFQARVLGVMDKQVYEELLDRAILYHENVNK
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNRLVILLILLAAVLFTAGCTEDGDNSTDAQQIQVSVVENLTALEQINTSVQEGPVLIKF
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCEEEEE
GAEWCGPCQQMKPILSDLAAEYTGKATVMSADIDQSRNLSAYFVTSYIPDSFVVVGLEDG
CCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEEEEEECCCCEEEEEECCC
EYVYMQDNGNVTKDRFQARVLGVMDKQVYEELLDRAILYHENVNK
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]