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The map label for this gene is pepQ [H]

Identifier: 21227076

GI number: 21227076

Start: 1154008

End: 1155210

Strand: Reverse

Name: pepQ [H]

Synonym: MM_0974

Alternate gene names: 21227076

Gene position: 1155210-1154008 (Counterclockwise)

Preceding gene: 21227078

Following gene: 21227073

Centisome position: 28.2

GC content: 44.72

Gene sequence:

>1203_bases
ATGATCAAGAAAGTACCTTCAACCGAACTGAAAAACCGTATGAGTTGCTTCAGAAAACAGATGGATATCTCAAATCCCGA
CTGGGAAATAGCTTTCATCTTCAGCAAAATCAATCTTTATTACTTTACCGGCACCATGCAGGATGGGATGCTTATTATTC
CGAGGAATAGAGAAGCAACTTTCTGGGTACGGCGCAGTTATGAGCGGGCTCTGGATGAATCGCTATTTTCCAGTATCAAA
CCTATGAACAGCTTCCGTGACGCAGCAGGGAGTGTGAGCAGGGTAAGCGAGCTTCCCGACACTGTATATCTGGAAACCGA
AATAGTCCCTCTGGCCCTCTACCAGAGGCTTCAAAAATACTTCCCATTTAAGAACGTTAAATCCGTTGATGCCCAGATTT
GCGCTGTTAGAGCGGTAAAAAGTGAGTATGAGCTTTCCCTGCTGCGAGAAGCCGGCAGAATTCATCAACATGTACTCGAA
GACCTTGTGCCCGGGATGCTGCGCGAAGGGATGAGTGAGGCTGACCTGTCAACGGAATTGTTCTCTGTTCTGGTCAAAGA
AGGGCACCACGGTGCATGCCGTTTTGGAATGTTTGATACGGAAATGATTCTCGGAAATGTCTGTTTTGGGGAAAGCTCCA
TTTATCCTACTTATTTTAATGGACCCGGCGGAAAGTATGGTTTATGCCCTGCTGCACCCGTGCTTGGGAGCCGTGACCGG
AAGCTAAGAAAAGGTGACCTTGTGTTTGTTGATGTGGGGTGCGGAGTTGATGGTTATCATACGGATAAAACCACAACATA
CATGTTTGGCTCTTCCCTTCCGCAGTATGCCATAGACATGCACAATAAATGTGTGGATATACAGAATGAAGCTGCAGCAA
TGTTAAAACCAGGGATTGCCCCTTCTGAAATCTACAATACCATAATGAATGGGCTTGATAAGGAATTTCTGCAAAACTTC
ATGGGTTTCGGCAACCGTAAAGTGAAATTTCTCGGGCATGGAGTCGGTTTATTAATTGACGAAACTCCCGTAATTGCCAA
AGGGTTTGATGAGTCCTTGCAGGAAGGAATGGTATTTGCTCTCGAACCTAAAAAAGGAATTGAAAATATCGGTATGGTTG
GAATCGAAAACACTTTCATAGTAACTGCTGATAGCGGAGAATGCATTACAGGAGATAATCCGGGATTGATTCCTGTATAT
TGA

Upstream 100 bases:

>100_bases
AACCTGTACATCTTTGTACTTTATACCTTGGTTTTATTTGGTTCTTCTTACGGGTTACACTTCTATAATTGTTAGCATAT
AACTTAGTAAAGGGATCTGC

Downstream 100 bases:

>100_bases
TTAGTAAATGAGAATAAAATTTACGTTTAGTGCGTTAAGAGCAAAAAAATTGGGAAGTATAGCTTTTAAAAATAGGATTT
ACGCAGTTGAACAAAAAACC

Product: Xaa-Pro aminopeptidase

Products: NA

Alternate protein names: X-Pro dipeptidase; Imidodipeptidase; Proline dipeptidase; Prolidase [H]

Number of amino acids: Translated: 400; Mature: 400

Protein sequence:

>400_residues
MIKKVPSTELKNRMSCFRKQMDISNPDWEIAFIFSKINLYYFTGTMQDGMLIIPRNREATFWVRRSYERALDESLFSSIK
PMNSFRDAAGSVSRVSELPDTVYLETEIVPLALYQRLQKYFPFKNVKSVDAQICAVRAVKSEYELSLLREAGRIHQHVLE
DLVPGMLREGMSEADLSTELFSVLVKEGHHGACRFGMFDTEMILGNVCFGESSIYPTYFNGPGGKYGLCPAAPVLGSRDR
KLRKGDLVFVDVGCGVDGYHTDKTTTYMFGSSLPQYAIDMHNKCVDIQNEAAAMLKPGIAPSEIYNTIMNGLDKEFLQNF
MGFGNRKVKFLGHGVGLLIDETPVIAKGFDESLQEGMVFALEPKKGIENIGMVGIENTFIVTADSGECITGDNPGLIPVY

Sequences:

>Translated_400_residues
MIKKVPSTELKNRMSCFRKQMDISNPDWEIAFIFSKINLYYFTGTMQDGMLIIPRNREATFWVRRSYERALDESLFSSIK
PMNSFRDAAGSVSRVSELPDTVYLETEIVPLALYQRLQKYFPFKNVKSVDAQICAVRAVKSEYELSLLREAGRIHQHVLE
DLVPGMLREGMSEADLSTELFSVLVKEGHHGACRFGMFDTEMILGNVCFGESSIYPTYFNGPGGKYGLCPAAPVLGSRDR
KLRKGDLVFVDVGCGVDGYHTDKTTTYMFGSSLPQYAIDMHNKCVDIQNEAAAMLKPGIAPSEIYNTIMNGLDKEFLQNF
MGFGNRKVKFLGHGVGLLIDETPVIAKGFDESLQEGMVFALEPKKGIENIGMVGIENTFIVTADSGECITGDNPGLIPVY
>Mature_400_residues
MIKKVPSTELKNRMSCFRKQMDISNPDWEIAFIFSKINLYYFTGTMQDGMLIIPRNREATFWVRRSYERALDESLFSSIK
PMNSFRDAAGSVSRVSELPDTVYLETEIVPLALYQRLQKYFPFKNVKSVDAQICAVRAVKSEYELSLLREAGRIHQHVLE
DLVPGMLREGMSEADLSTELFSVLVKEGHHGACRFGMFDTEMILGNVCFGESSIYPTYFNGPGGKYGLCPAAPVLGSRDR
KLRKGDLVFVDVGCGVDGYHTDKTTTYMFGSSLPQYAIDMHNKCVDIQNEAAAMLKPGIAPSEIYNTIMNGLDKEFLQNF
MGFGNRKVKFLGHGVGLLIDETPVIAKGFDESLQEGMVFALEPKKGIENIGMVGIENTFIVTADSGECITGDNPGLIPVY

Specific function: Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position [H]

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family. Archaeal-type prolidase subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: =3.4.13.9 [H]

Molecular weight: Translated: 44635; Mature: 44635

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKKVPSTELKNRMSCFRKQMDISNPDWEIAFIFSKINLYYFTGTMQDGMLIIPRNREAT
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEEEEEECCCCEEEEECCCCCC
FWVRRSYERALDESLFSSIKPMNSFRDAAGSVSRVSELPDTVYLETEIVPLALYQRLQKY
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
FPFKNVKSVDAQICAVRAVKSEYELSLLREAGRIHQHVLEDLVPGMLREGMSEADLSTEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FSVLVKEGHHGACRFGMFDTEMILGNVCFGESSIYPTYFNGPGGKYGLCPAAPVLGSRDR
HHHHHHCCCCCEEEECCCCHHHHHHEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
KLRKGDLVFVDVGCGVDGYHTDKTTTYMFGSSLPQYAIDMHNKCVDIQNEAAAMLKPGIA
CCCCCCEEEEEECCCCCCEECCCEEEEEECCCCCHHHHHHCCCEECCCCHHHHHHCCCCC
PSEIYNTIMNGLDKEFLQNFMGFGNRKVKFLGHGVGLLIDETPVIAKGFDESLQEGMVFA
HHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCEEEEECCCCHHCCCHHHHHCCCEEE
LEPKKGIENIGMVGIENTFIVTADSGECITGDNPGLIPVY
ECCCCCCCCCCEEEECCEEEEEECCCCEEECCCCCEEECC
>Mature Secondary Structure
MIKKVPSTELKNRMSCFRKQMDISNPDWEIAFIFSKINLYYFTGTMQDGMLIIPRNREAT
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEEEEEEEEECCCCEEEEECCCCCC
FWVRRSYERALDESLFSSIKPMNSFRDAAGSVSRVSELPDTVYLETEIVPLALYQRLQKY
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHCHHHHHHHCCCEEEEEECHHHHHHHHHHHHH
FPFKNVKSVDAQICAVRAVKSEYELSLLREAGRIHQHVLEDLVPGMLREGMSEADLSTEL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
FSVLVKEGHHGACRFGMFDTEMILGNVCFGESSIYPTYFNGPGGKYGLCPAAPVLGSRDR
HHHHHHCCCCCEEEECCCCHHHHHHEEEECCCCCCCEEECCCCCCCCCCCCCCCCCCCCC
KLRKGDLVFVDVGCGVDGYHTDKTTTYMFGSSLPQYAIDMHNKCVDIQNEAAAMLKPGIA
CCCCCCEEEEEECCCCCCEECCCEEEEEECCCCCHHHHHHCCCEECCCCHHHHHHCCCCC
PSEIYNTIMNGLDKEFLQNFMGFGNRKVKFLGHGVGLLIDETPVIAKGFDESLQEGMVFA
HHHHHHHHHHCCCHHHHHHHHCCCCCEEEEEECCCEEEEECCCCHHCCCHHHHHCCCEEE
LEPKKGIENIGMVGIENTFIVTADSGECITGDNPGLIPVY
ECCCCCCCCCCEEEECCEEEEEECCCCEEECCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9733678; 11223522; 11210522 [H]