Click here to switch to the map view.

The map label for this gene is divJ [H]

Identifier: 21227050

GI number: 21227050

Start: 1123813

End: 1125006

Strand: Direct

Name: divJ [H]

Synonym: MM_0948

Alternate gene names: 21227050

Gene position: 1123813-1125006 (Clockwise)

Preceding gene: 21227046

Following gene: 21227059

Centisome position: 27.43

GC content: 42.29

Gene sequence:

>1194_bases
GTGAGTGTCGAGAAATATCTGACTTCATTTCAATTAGAGATTATTAACACCGGCACGCTTTCGAAAGGTTCCCCGCTTCC
TGAATCAGCAGTAAAAGAACTCATGAAAGAAAAGAGTGAAAAAGCCTTTTCTGAAGGATTCCCCGGCTTTAGAATGAATG
TTAGTATTACCAGGAAGGGAGGTTCCCTGAATCCCGACCCTGAAAAGCTGGAAGAAAACCTTAAAGAGATTAACCGGGAT
AACGAAAGAAAGCTTACATATCTATGTACTTTTCCTCTTGAAGAATTATCGGGCAGCGAACTTCTCAGGCTTGTGGAGGA
AAAGGGCGTTCTCGTTAAAAGAAAAGGTGGCTGGGAATGCCTGATGCATACATGCAACATAAACGGGCAAAAAGAGCTTG
AAACGACCCTCCTTAGAGCAAAAAAAGATGCTGAAGCTACAAACCGGGCAAAGAACAGTTTCATAATGAATATGAGCCAT
GAGCTCAGGACCCCTCTCAATTCGGTTATAGGTTTTTCTGACCTGCTGCTGGAAGGAGCATTCGGGCCCATGAATACAAA
GCAGTCAAAATATGTCAATAATATCCTTATAAGCGGAAAAAATCTGCTTGAGATCATTAATAACCTGCTTGATATCTCGA
GGCTTGAAGCTGGAGAAAAGACTCTCAAATATGAGGACGTGGATGTTGCAAGCCTCATAGGAGAGGTTAGAATGAACCTC
CTTTCACCTGCTTCGGTAAAGAAGATCAATGTCGAACTGAAGATAGACCCCTCTGTAGGAAATGTTGAAGCTGATATTTC
AAAACTCAGACAGATCCTGTATAACCTGGTAAGTAACGCCATAAAGTTCACTCCAGCGAGAGGAAAGGTTGTAATCAGCG
CCTGCAAAAAAGAAGGAGTTCTCGAAGTAAAAGTCTCGGATAACGGGATAGGGATTTCTGAAGATAGCTACGAGAAAATA
TTCATGCCTTTCACACAGGCAGATTCTTCCGCAGCACGAGGATATGGGGGAGCAGGACTTGGGTTATTTATTGTCAGAAA
CTTTGTAGACCTGCATGGAGGGGATATAAGTGTGAACTCCGAAGTAGGGAAAGGAAGTACATTTACTTTCACCATTCCGG
CAAAACCAGAGAACACTTCCCTTCAGGAGAACGAAACAAAAAAGTGGAATCATCTACAAAAGGAAAAAAATTGA

Upstream 100 bases:

>100_bases
CTATTTTAAACAGGGAATTGAGAGGGGAGAGTACTGCCTCTGGACTGTTACGGACGCACTTGAAGAAGAAAGAGTAAAAA
AAGAACTTGAGAAAGCAGAT

Downstream 100 bases:

>100_bases
AAAAAACAGAACTATTAAGTGAAGATGAAAATTGAAAATATATAACTTTCATTAAATACGGGCCTGGATTAAAACCTCTA
TTTTAAGGATGGAGATCCAG

Product: sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MSVEKYLTSFQLEIINTGTLSKGSPLPESAVKELMKEKSEKAFSEGFPGFRMNVSITRKGGSLNPDPEKLEENLKEINRD
NERKLTYLCTFPLEELSGSELLRLVEEKGVLVKRKGGWECLMHTCNINGQKELETTLLRAKKDAEATNRAKNSFIMNMSH
ELRTPLNSVIGFSDLLLEGAFGPMNTKQSKYVNNILISGKNLLEIINNLLDISRLEAGEKTLKYEDVDVASLIGEVRMNL
LSPASVKKINVELKIDPSVGNVEADISKLRQILYNLVSNAIKFTPARGKVVISACKKEGVLEVKVSDNGIGISEDSYEKI
FMPFTQADSSAARGYGGAGLGLFIVRNFVDLHGGDISVNSEVGKGSTFTFTIPAKPENTSLQENETKKWNHLQKEKN

Sequences:

>Translated_397_residues
MSVEKYLTSFQLEIINTGTLSKGSPLPESAVKELMKEKSEKAFSEGFPGFRMNVSITRKGGSLNPDPEKLEENLKEINRD
NERKLTYLCTFPLEELSGSELLRLVEEKGVLVKRKGGWECLMHTCNINGQKELETTLLRAKKDAEATNRAKNSFIMNMSH
ELRTPLNSVIGFSDLLLEGAFGPMNTKQSKYVNNILISGKNLLEIINNLLDISRLEAGEKTLKYEDVDVASLIGEVRMNL
LSPASVKKINVELKIDPSVGNVEADISKLRQILYNLVSNAIKFTPARGKVVISACKKEGVLEVKVSDNGIGISEDSYEKI
FMPFTQADSSAARGYGGAGLGLFIVRNFVDLHGGDISVNSEVGKGSTFTFTIPAKPENTSLQENETKKWNHLQKEKN
>Mature_396_residues
SVEKYLTSFQLEIINTGTLSKGSPLPESAVKELMKEKSEKAFSEGFPGFRMNVSITRKGGSLNPDPEKLEENLKEINRDN
ERKLTYLCTFPLEELSGSELLRLVEEKGVLVKRKGGWECLMHTCNINGQKELETTLLRAKKDAEATNRAKNSFIMNMSHE
LRTPLNSVIGFSDLLLEGAFGPMNTKQSKYVNNILISGKNLLEIINNLLDISRLEAGEKTLKYEDVDVASLIGEVRMNLL
SPASVKKINVELKIDPSVGNVEADISKLRQILYNLVSNAIKFTPARGKVVISACKKEGVLEVKVSDNGIGISEDSYEKIF
MPFTQADSSAARGYGGAGLGLFIVRNFVDLHGGDISVNSEVGKGSTFTFTIPAKPENTSLQENETKKWNHLQKEKN

Specific function: Kinase required for the regulation of cell division and differentiation. Makes part of a signal transduction pathway, activating pleD by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=43.5146443514644, Blast_Score=164, Evalue=8e-42,
Organism=Escherichia coli, GI48994928, Length=241, Percent_Identity=37.7593360995851, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=32.156862745098, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788713, Length=265, Percent_Identity=30.9433962264151, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI87081816, Length=242, Percent_Identity=33.0578512396694, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1786600, Length=246, Percent_Identity=30.4878048780488, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=29.7071129707113, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1790436, Length=218, Percent_Identity=29.8165137614679, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=25.4826254826255, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI87082128, Length=267, Percent_Identity=25.4681647940075, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790861, Length=205, Percent_Identity=31.219512195122, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=235, Percent_Identity=26.3829787234043, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=228, Percent_Identity=25, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1790346, Length=224, Percent_Identity=28.125, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1787894, Length=238, Percent_Identity=25.6302521008403, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788279, Length=232, Percent_Identity=27.1551724137931, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790551, Length=215, Percent_Identity=26.046511627907, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790300, Length=277, Percent_Identity=24.187725631769, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789808, Length=226, Percent_Identity=24.7787610619469, Blast_Score=63, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=77, Percent_Identity=44.1558441558442, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 43924; Mature: 43793

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVEKYLTSFQLEIINTGTLSKGSPLPESAVKELMKEKSEKAFSEGFPGFRMNVSITRKG
CCHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
GSLNPDPEKLEENLKEINRDNERKLTYLCTFPLEELSGSELLRLVEEKGVLVKRKGGWEC
CCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCHHHCCHHHHHHHHHHCCEEEEECCCCEE
LMHTCNINGQKELETTLLRAKKDAEATNRAKNSFIMNMSHELRTPLNSVIGFSDLLLEGA
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHCCHHHHHHHHHHHHHCC
FGPMNTKQSKYVNNILISGKNLLEIINNLLDISRLEAGEKTLKYEDVDVASLIGEVRMNL
CCCCCCCHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCHHCEECCCHHHHHHHHHHHHH
LSPASVKKINVELKIDPSVGNVEADISKLRQILYNLVSNAIKFTPARGKVVISACKKEGV
CCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCE
LEVKVSDNGIGISEDSYEKIFMPFTQADSSAARGYGGAGLGLFIVRNFVDLHGGDISVNS
EEEEECCCCCCCCCCCCCEEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCEEECC
EVGKGSTFTFTIPAKPENTSLQENETKKWNHLQKEKN
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCC
>Mature Secondary Structure 
SVEKYLTSFQLEIINTGTLSKGSPLPESAVKELMKEKSEKAFSEGFPGFRMNVSITRKG
CHHHHHHHEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
GSLNPDPEKLEENLKEINRDNERKLTYLCTFPLEELSGSELLRLVEEKGVLVKRKGGWEC
CCCCCCHHHHHHHHHHHCCCCCCEEEEEEECCHHHCCHHHHHHHHHHCCEEEEECCCCEE
LMHTCNINGQKELETTLLRAKKDAEATNRAKNSFIMNMSHELRTPLNSVIGFSDLLLEGA
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHCCHHHHHHHHHHHHHCC
FGPMNTKQSKYVNNILISGKNLLEIINNLLDISRLEAGEKTLKYEDVDVASLIGEVRMNL
CCCCCCCHHHHHHHHEECCHHHHHHHHHHHHHHHHCCCCHHCEECCCHHHHHHHHHHHHH
LSPASVKKINVELKIDPSVGNVEADISKLRQILYNLVSNAIKFTPARGKVVISACKKEGV
CCCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCEEEEECCCCCE
LEVKVSDNGIGISEDSYEKIFMPFTQADSSAARGYGGAGLGLFIVRNFVDLHGGDISVNS
EEEEECCCCCCCCCCCCCEEEEEECCCCCCHHCCCCCCCHHHHHHHHHHHHCCCCEEECC
EVGKGSTFTFTIPAKPENTSLQENETKKWNHLQKEKN
CCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1438215; 11259647 [H]