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The map label for this gene is kamA [H]

Identifier: 21227036

GI number: 21227036

Start: 1102502

End: 1103761

Strand: Direct

Name: kamA [H]

Synonym: MM_0934

Alternate gene names: 21227036

Gene position: 1102502-1103761 (Clockwise)

Preceding gene: 21227031

Following gene: 21227037

Centisome position: 26.91

GC content: 47.38

Gene sequence:

>1260_bases
GTGAAATCCAGGATAAAAGACTGTTTTAATGCATCCGAAGAAGAATTTTCAGACTGGAAATGGCAGTATAGAAATAGAAT
TACCACCGTTGAAGAACTCGAAAAACTGATTCTGCTTTCGGACACGGAAAAGAGAGACATAAAGAAAGCGCTTGAGGTTT
TTCCAATGGCTATTTCCCCTTATTATGCCTCACTTATCGACCCTGACGACCCGGAATGTCCTGTAAGACTGCAGGCTGTG
CCACAGTCAGCAGAGCTTCAAAAATCGTCCTGGGAACTTGAAGACCCTCTCTGTGAGGACCAGGACTCACCATCTGAAGA
GAGCTGTATAACCCACAGGTACCCGGATAGGGTTCTTTTCCTAATCTCAAACCGCTGTGGGATGTACTGCAGGCACTGCA
CTCGCAAGCGCAGGGTCGGCAACAGAGAGCATGACTATTCTGAAAAAGCAATCCGGGAAGGAATCGAGTACATCCGGATG
CACCATGAAGTAAGGGATGTGCTTCTTTCAGGAGGAGATGCCCTGCTGGTATCTGATGAAAGGCTGGACTGGCTTTTAGG
TGAACTCTTCAGCATTCCTCACGTAGAGATAGTAAGGTTAGGTACAAGAGCACCTGTGACCCTGCCCCAGCGCATAACCC
CGGAACTGTGCGAAATCCTTGGAAAATATCCGTCGGTCTGGCTCAATACTCATTTTAACCACCCAAAAGAGATCACTCCT
GAAGCTAAAAAGGCAATGAATATGCTCGCCTGTGCTGGAATTCCACTTGGCAACCAGTCCGTACTCCTCAGAAGAGTAAA
TGACTGTCCGGTGATAATCAAAAACCTCTGTCACGAACTCCTGAAGATAAAGACCAGACCTTATTACCTCTATCAGTGTG
ACCTCTCTTTCGGGCTGGAACATTTCAGAACCTCAGTTGCAAGGGGCATAGAAATAATAGAGATGCTAAGAGGGCACACA
TCAGGGCTTGCAGTCCCTACTTTTGTGGTCGACGCTCCGGGAGGGGGAGGAAAAATTCCTGTCGGGCCCAATTACCTGAT
CTCAAGCTCGGATACAGGAGTTACTCTCAGAAACTACGAAGGGGTAATCTGCGTATATCCGGAACCTGCAGAGTACTCCT
CAAAGTGCCAGCAAAAATGTACTATCTGTGATAAGCACCCAGGGCTTAAAAGTGATACAGGGCTTGCCAGGCTTTATGAT
GAGGAAAATGATGTTATCGCCCTTGAGCCGGAAGGACTCGAAAGAAAACAGCGTTTCTGA

Upstream 100 bases:

>100_bases
TAGTTCATAGAACATATTTAAATTTTTCATATGTTATAGATATTTTATGTTCTGGACATCTGTCCCTTAATTTTTCTTCC
AGCAGTCACGAGGTTTAAAC

Downstream 100 bases:

>100_bases
AAGGAAAAAATTCCGGAAAAACAGGTTATCTAAAATTAAAAAATGTATTTAAACTGAGGAGGGCCAGCCACGGAAAAAAA
CGTCTCCTTAACGCTCGAGA

Product: lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MKSRIKDCFNASEEEFSDWKWQYRNRITTVEELEKLILLSDTEKRDIKKALEVFPMAISPYYASLIDPDDPECPVRLQAV
PQSAELQKSSWELEDPLCEDQDSPSEESCITHRYPDRVLFLISNRCGMYCRHCTRKRRVGNREHDYSEKAIREGIEYIRM
HHEVRDVLLSGGDALLVSDERLDWLLGELFSIPHVEIVRLGTRAPVTLPQRITPELCEILGKYPSVWLNTHFNHPKEITP
EAKKAMNMLACAGIPLGNQSVLLRRVNDCPVIIKNLCHELLKIKTRPYYLYQCDLSFGLEHFRTSVARGIEIIEMLRGHT
SGLAVPTFVVDAPGGGGKIPVGPNYLISSSDTGVTLRNYEGVICVYPEPAEYSSKCQQKCTICDKHPGLKSDTGLARLYD
EENDVIALEPEGLERKQRF

Sequences:

>Translated_419_residues
MKSRIKDCFNASEEEFSDWKWQYRNRITTVEELEKLILLSDTEKRDIKKALEVFPMAISPYYASLIDPDDPECPVRLQAV
PQSAELQKSSWELEDPLCEDQDSPSEESCITHRYPDRVLFLISNRCGMYCRHCTRKRRVGNREHDYSEKAIREGIEYIRM
HHEVRDVLLSGGDALLVSDERLDWLLGELFSIPHVEIVRLGTRAPVTLPQRITPELCEILGKYPSVWLNTHFNHPKEITP
EAKKAMNMLACAGIPLGNQSVLLRRVNDCPVIIKNLCHELLKIKTRPYYLYQCDLSFGLEHFRTSVARGIEIIEMLRGHT
SGLAVPTFVVDAPGGGGKIPVGPNYLISSSDTGVTLRNYEGVICVYPEPAEYSSKCQQKCTICDKHPGLKSDTGLARLYD
EENDVIALEPEGLERKQRF
>Mature_419_residues
MKSRIKDCFNASEEEFSDWKWQYRNRITTVEELEKLILLSDTEKRDIKKALEVFPMAISPYYASLIDPDDPECPVRLQAV
PQSAELQKSSWELEDPLCEDQDSPSEESCITHRYPDRVLFLISNRCGMYCRHCTRKRRVGNREHDYSEKAIREGIEYIRM
HHEVRDVLLSGGDALLVSDERLDWLLGELFSIPHVEIVRLGTRAPVTLPQRITPELCEILGKYPSVWLNTHFNHPKEITP
EAKKAMNMLACAGIPLGNQSVLLRRVNDCPVIIKNLCHELLKIKTRPYYLYQCDLSFGLEHFRTSVARGIEIIEMLRGHT
SGLAVPTFVVDAPGGGGKIPVGPNYLISSSDTGVTLRNYEGVICVYPEPAEYSSKCQQKCTICDKHPGLKSDTGLARLYD
EENDVIALEPEGLERKQRF

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=326, Percent_Identity=30.9815950920245, Blast_Score=160, Evalue=1e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 47796; Mature: 47796

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSRIKDCFNASEEEFSDWKWQYRNRITTVEELEKLILLSDTEKRDIKKALEVFPMAISP
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
YYASLIDPDDPECPVRLQAVPQSAELQKSSWELEDPLCEDQDSPSEESCITHRYPDRVLF
HHHHHCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCHHCHHHCCCCCEEEE
LISNRCGMYCRHCTRKRRVGNREHDYSEKAIREGIEYIRMHHEVRDVLLSGGDALLVSDE
EECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECH
RLDWLLGELFSIPHVEIVRLGTRAPVTLPQRITPELCEILGKYPSVWLNTHFNHPKEITP
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCH
EAKKAMNMLACAGIPLGNQSVLLRRVNDCPVIIKNLCHELLKIKTRPYYLYQCDLSFGLE
HHHHHHHHHHHCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHH
HFRTSVARGIEIIEMLRGHTSGLAVPTFVVDAPGGGGKIPVGPNYLISSSDTGVTLRNYE
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCEEEECCC
GVICVYPEPAEYSSKCQQKCTICDKHPGLKSDTGLARLYDEENDVIALEPEGLERKQRF
CEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHEEECCCCCEEEECCCCCHHHCCC
>Mature Secondary Structure
MKSRIKDCFNASEEEFSDWKWQYRNRITTVEELEKLILLSDTEKRDIKKALEVFPMAISP
CCCHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCC
YYASLIDPDDPECPVRLQAVPQSAELQKSSWELEDPLCEDQDSPSEESCITHRYPDRVLF
HHHHHCCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCCCCHHCHHHCCCCCEEEE
LISNRCGMYCRHCTRKRRVGNREHDYSEKAIREGIEYIRMHHEVRDVLLSGGDALLVSDE
EECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECH
RLDWLLGELFSIPHVEIVRLGTRAPVTLPQRITPELCEILGKYPSVWLNTHFNHPKEITP
HHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCCCCEEEECCCCCCCCCCH
EAKKAMNMLACAGIPLGNQSVLLRRVNDCPVIIKNLCHELLKIKTRPYYLYQCDLSFGLE
HHHHHHHHHHHCCCCCCCCHHHEEECCCCHHHHHHHHHHHHHHCCCCEEEEEECHHHHHH
HFRTSVARGIEIIEMLRGHTSGLAVPTFVVDAPGGGGKIPVGPNYLISSSDTGVTLRNYE
HHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCCEEEECCCCCEEEECCC
GVICVYPEPAEYSSKCQQKCTICDKHPGLKSDTGLARLYDEENDVIALEPEGLERKQRF
CEEEECCCCCCHHHHHHHHCCCCCCCCCCCCCCCHHEEECCCCCEEEECCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]