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The map label for this gene is eif5a [H]

Identifier: 21227024

GI number: 21227024

Start: 1089329

End: 1089715

Strand: Direct

Name: eif5a [H]

Synonym: MM_0922

Alternate gene names: 21227024

Gene position: 1089329-1089715 (Clockwise)

Preceding gene: 21227023

Following gene: 21227025

Centisome position: 26.59

GC content: 42.89

Gene sequence:

>387_bases
ATGAAACAGCAGGTAGAAGTAAAGGAACTTAAAGAAGGAAAATATGTAATTATTGACGATGAAGCATGTGTGATAAAAAG
CATTACCAAGTCAAAACCCGGGAAACACGGAGCAGCAAAGGCAAGAGTAGAGGCAATAGGCCTTTTTGACGGCCAGAAGC
GCTCCTATATCGGGTCCGTAGCAAACAAAGTTTATGTCCCGATCGTGGAAAGAAAGAGTGCACAGGTTATCTCAATCACC
GGAGACATTGCCCAGCTTATGGACATGGGAGACTTTTCAACTTTTGAAATCGTGATTCCTGATGAATTAAAGGACAGAGT
GAAAGAGGGTGAAGAGGTATCCTATATCACAGCCCTCGGAAAGGTCAAACTCGATATAAGGACGTAA

Upstream 100 bases:

>100_bases
TTATACCACTTCACCGGAATTGGCGCTGAAAACTTTAGATCAAATCCGGTATGACGTTTACAGCTTATTATAAATATATA
AAATGTAAGGGAGAATCACT

Downstream 100 bases:

>100_bases
TCATTGAAAAACAGACAAACAAAAACTCAGGTTAATACAGAGCCTGAGTTCTCTTTTTTACTAATTAAACAATTTACATC
AGGTATAATTTACATCAGGT

Product: translation initiation factor IF-5A

Products: NA

Alternate protein names: Hypusine-containing protein; eIF-5A [H]

Number of amino acids: Translated: 128; Mature: 128

Protein sequence:

>128_residues
MKQQVEVKELKEGKYVIIDDEACVIKSITKSKPGKHGAAKARVEAIGLFDGQKRSYIGSVANKVYVPIVERKSAQVISIT
GDIAQLMDMGDFSTFEIVIPDELKDRVKEGEEVSYITALGKVKLDIRT

Sequences:

>Translated_128_residues
MKQQVEVKELKEGKYVIIDDEACVIKSITKSKPGKHGAAKARVEAIGLFDGQKRSYIGSVANKVYVPIVERKSAQVISIT
GDIAQLMDMGDFSTFEIVIPDELKDRVKEGEEVSYITALGKVKLDIRT
>Mature_128_residues
MKQQVEVKELKEGKYVIIDDEACVIKSITKSKPGKHGAAKARVEAIGLFDGQKRSYIGSVANKVYVPIVERKSAQVISIT
GDIAQLMDMGDFSTFEIVIPDELKDRVKEGEEVSYITALGKVKLDIRT

Specific function: Functions by promoting the formation of the first peptide bond [H]

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the eIF-5A family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR019769
- InterPro:   IPR001884
- InterPro:   IPR022847
- InterPro:   IPR020189
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF01287 eIF-5a [H]

EC number: NA

Molecular weight: Translated: 14144; Mature: 14144

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS00302 IF5A_HYPUSINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQQVEVKELKEGKYVIIDDEACVIKSITKSKPGKHGAAKARVEAIGLFDGQKRSYIGSV
CCCCCCHHHHCCCCEEEECCCCCEEHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHH
ANKVYVPIVERKSAQVISITGDIAQLMDMGDFSTFEIVIPDELKDRVKEGEEVSYITALG
HCEEEEEEECCCCCEEEEEECHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCEEEEEEEE
KVKLDIRT
EEEEEEEC
>Mature Secondary Structure
MKQQVEVKELKEGKYVIIDDEACVIKSITKSKPGKHGAAKARVEAIGLFDGQKRSYIGSV
CCCCCCHHHHCCCCEEEECCCCCEEHHHHCCCCCCCCCCCEEEEEEECCCCCCHHHHHHH
ANKVYVPIVERKSAQVISITGDIAQLMDMGDFSTFEIVIPDELKDRVKEGEEVSYITALG
HCEEEEEEECCCCCEEEEEECHHHHHHCCCCCCEEEEEECHHHHHHHHCCCCEEEEEEEE
KVKLDIRT
EEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]