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The map label for this gene is selD [C]

Identifier: 21226863

GI number: 21226863

Start: 909410

End: 910390

Strand: Direct

Name: selD [C]

Synonym: MM_0761

Alternate gene names: 21226863

Gene position: 909410-910390 (Clockwise)

Preceding gene: 21226861

Following gene: 21226865

Centisome position: 22.2

GC content: 48.93

Gene sequence:

>981_bases
TTGAACCTGGAACAGCTAGCAGAAAGGATAAGGAGTTTCGAAGGGGTTACCCGAAAAAAACAGATCGAGGATATAGTCTC
TATCTTTGAAGCCGTCCGCCCGGAATACGGGAACGCTATCGTTGATTTCGGGGACGATGCTGCAGTAATTGACATAGGAG
GAGATGACGTTATCCTCTTTGCAGCTGATGGTATCTGGGGACGGCTTCTAGACGCGAGCCCCTGGTGGGCAGGTTACGGG
GCTGTTGTTGTGAACGTAAATGACATTGCAGCGATGGGAGGAAAACCACTTGCCATGGTGGATATCGCCTCTGCAAATTC
CCCAAAAGCATGCAGGGAACTGATGGAAGGCCTGGCTGAAGGAGTAAGAAAATTCGGAGTCCCTGTTGTTGGAGGGCATG
TCCACCCGGATACAAAGTACAATTCCCTTTCCGTTGCCATAATAGGAATCGTCAAAAAAGACTGTGTGATCAGAAGTGAT
ACTGCAAAACCAGGCGACCTTGTAATTGCAGCCTATGATATGGACGGAAAAATCGGCCCTAATTCCCCTTATAGCTGGGA
CACGACATCTTTTAAAGAGCCTTCCGTGCTCAGGGAAAGCTACCTTGTAACCCAGGAAATAGCACAGAAAAAGCTTGCAA
GCGCCGGAAAGGACATCAGCAACCCCGGGCTGATAGGAACTCTCGGGATGCTCTGTGAGACGAGCAGGGTAGGAGCCTCT
GTCGATCTGGAAAAAGTCCCGAGACCTGAAGGCGTGGATTTTGAGCAGTGGCTGAAAGTGCACCCGGGAACTGGTTATGT
GTTTACTGCAGACCCGGAAAAAGCCGGAGAGTGTGTGGCTGTGTTTGAAAAGGCAGGGCTTACAGCTGCAGTAGTAGGAA
AAATTGAAGAGGGGTTAAAGCTTGACATGTATGATAAAACAGGCAGAGTAACCGTTTTTGACTTCTCAAAGGACAGTATT
ACAGGCATAGGTTCCGAATAA

Upstream 100 bases:

>100_bases
TCTGATCAGATAACAGTAAGATCAAATTACTGTAAATCTGATCTTAATATTAACTACTAGATAGCCCAATACAAGTAAAA
AAACAAACAGGAGCCATTGA

Downstream 100 bases:

>100_bases
ACGGGACCTTTCTGCTTGAAATATTTACTTCAAAAATATTGTTCTGCTGAAAAGTTATTATTTTACTTATCCAGCATCTG
CTCCTGTTTATTTTATTATT

Product: thiamin-monophosphate kinase

Products: ADP; thiamine diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MNLEQLAERIRSFEGVTRKKQIEDIVSIFEAVRPEYGNAIVDFGDDAAVIDIGGDDVILFAADGIWGRLLDASPWWAGYG
AVVVNVNDIAAMGGKPLAMVDIASANSPKACRELMEGLAEGVRKFGVPVVGGHVHPDTKYNSLSVAIIGIVKKDCVIRSD
TAKPGDLVIAAYDMDGKIGPNSPYSWDTTSFKEPSVLRESYLVTQEIAQKKLASAGKDISNPGLIGTLGMLCETSRVGAS
VDLEKVPRPEGVDFEQWLKVHPGTGYVFTADPEKAGECVAVFEKAGLTAAVVGKIEEGLKLDMYDKTGRVTVFDFSKDSI
TGIGSE

Sequences:

>Translated_326_residues
MNLEQLAERIRSFEGVTRKKQIEDIVSIFEAVRPEYGNAIVDFGDDAAVIDIGGDDVILFAADGIWGRLLDASPWWAGYG
AVVVNVNDIAAMGGKPLAMVDIASANSPKACRELMEGLAEGVRKFGVPVVGGHVHPDTKYNSLSVAIIGIVKKDCVIRSD
TAKPGDLVIAAYDMDGKIGPNSPYSWDTTSFKEPSVLRESYLVTQEIAQKKLASAGKDISNPGLIGTLGMLCETSRVGAS
VDLEKVPRPEGVDFEQWLKVHPGTGYVFTADPEKAGECVAVFEKAGLTAAVVGKIEEGLKLDMYDKTGRVTVFDFSKDSI
TGIGSE
>Mature_326_residues
MNLEQLAERIRSFEGVTRKKQIEDIVSIFEAVRPEYGNAIVDFGDDAAVIDIGGDDVILFAADGIWGRLLDASPWWAGYG
AVVVNVNDIAAMGGKPLAMVDIASANSPKACRELMEGLAEGVRKFGVPVVGGHVHPDTKYNSLSVAIIGIVKKDCVIRSD
TAKPGDLVIAAYDMDGKIGPNSPYSWDTTSFKEPSVLRESYLVTQEIAQKKLASAGKDISNPGLIGTLGMLCETSRVGAS
VDLEKVPRPEGVDFEQWLKVHPGTGYVFTADPEKAGECVAVFEKAGLTAAVVGKIEEGLKLDMYDKTGRVTVFDFSKDSI
TGIGSE

Specific function: Synthesizes Selenophosphate From Selenide And ATP. [C]

COG id: COG2144

COG function: function code R; Selenophosphate synthetase-related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788062, Length=233, Percent_Identity=28.3261802575107, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR017668
- InterPro:   IPR016188
- InterPro:   IPR011413 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: 2.7.4.16

Molecular weight: Translated: 34860; Mature: 34860

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLEQLAERIRSFEGVTRKKQIEDIVSIFEAVRPEYGNAIVDFGDDAAVIDIGGDDVILF
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCEEEEE
AADGIWGRLLDASPWWAGYGAVVVNVNDIAAMGGKPLAMVDIASANSPKACRELMEGLAE
EECCCHHHHCCCCCCCCCCCEEEEEEHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
GVRKFGVPVVGGHVHPDTKYNSLSVAIIGIVKKDCVIRSDTAKPGDLVIAAYDMDGKIGP
HHHHHCCCEECCEECCCCCCCCEEEEEEEEECCCEEEECCCCCCCCEEEEEEECCCCCCC
NSPYSWDTTSFKEPSVLRESYLVTQEIAQKKLASAGKDISNPGLIGTLGMLCETSRVGAS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
VDLEKVPRPEGVDFEQWLKVHPGTGYVFTADPEKAGECVAVFEKAGLTAAVVGKIEEGLK
CCHHHCCCCCCCCHHHHHEECCCCCEEEECCCHHHCCEEEEHHHCCCCEEEHHHHHCCCE
LDMYDKTGRVTVFDFSKDSITGIGSE
EEEECCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure
MNLEQLAERIRSFEGVTRKKQIEDIVSIFEAVRPEYGNAIVDFGDDAAVIDIGGDDVILF
CCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCEEEEEECCCEEEEE
AADGIWGRLLDASPWWAGYGAVVVNVNDIAAMGGKPLAMVDIASANSPKACRELMEGLAE
EECCCHHHHCCCCCCCCCCCEEEEEEHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHH
GVRKFGVPVVGGHVHPDTKYNSLSVAIIGIVKKDCVIRSDTAKPGDLVIAAYDMDGKIGP
HHHHHCCCEECCEECCCCCCCCEEEEEEEEECCCEEEECCCCCCCCEEEEEEECCCCCCC
NSPYSWDTTSFKEPSVLRESYLVTQEIAQKKLASAGKDISNPGLIGTLGMLCETSRVGAS
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCC
VDLEKVPRPEGVDFEQWLKVHPGTGYVFTADPEKAGECVAVFEKAGLTAAVVGKIEEGLK
CCHHHCCCCCCCCHHHHHEECCCCCEEEECCCHHHCCEEEEHHHCCCCEEEHHHHHCCCE
LDMYDKTGRVTVFDFSKDSITGIGSE
EEEECCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; thiamine phosphate

Specific reaction: ATP + thiamine phosphate = ADP + thiamine diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]