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The map label for this gene is queC

Identifier: 21226855

GI number: 21226855

Start: 903166

End: 903861

Strand: Direct

Name: queC

Synonym: MM_0753

Alternate gene names: 21226855

Gene position: 903166-903861 (Clockwise)

Preceding gene: 21226853

Following gene: 21226856

Centisome position: 22.05

GC content: 47.99

Gene sequence:

>696_bases
ATGAAAGCTATAACCCTCCTGAGCAGTGGGCTTGATTCCGTAGCAGCGCTTGCGATTGCTGCCGAAAGCCTTGAAATTGA
GATGGCAATTACATTTGACTACGGGCAGAGAGCAGGGCAGCGGGAAATGGAATATTCCGAAAAGGTCTGCGAACACTTCG
GAATAGAGCAGAGGATAATAAAGCTGGACTGGCTTGGAGAAATAACACATACATCCCTTGTAAACAGGGATGAAGAAGTT
CCTTCCCTGTCTTTTGAGGATATTGATGAAAACTCCCCTTCCATGATTACCGAGTATTCTGCAAAGGCTGTCTGGGTCCC
TAACAGGAACGGGGTTATGTTAAACATCGCAGGGAGCTTTGCCGAAAGCAGGGGATGTGATTACATAGTTGTGGGCTTCA
ACGGAGAAGAAGCCGGAACCTTTCCTGATAATTCCCGTGATTACATACAGGCGGTGGACAATGCCTTTTCTTACTCCACA
CAGAACGGAGTGAAAGTGCTTGCTCCCCTGGCAGAGATGGGAAAAACTGAAATCGTTAAAAAAGCTCTTGAAGCAGAAGC
TCCGCTTGAATACAGCTGGAGCTGCTATCACGGAGGGGAAATCCCCTGCGGAAAGTGTGAAAGCTGCGTGCGCAGGGCAA
GGGCATTCAAAAATATTGGTATAAAGGACCCGCTTCTGGAAAGGTTGGGGATCTGA

Upstream 100 bases:

>100_bases
ATAGATATTACTCCAATAATCTCTGAGGAATATTTACAGAACCTCCAGAGAGTACCAGATAAAGAAAATTTTCCATAAAA
TTAGAGTCAGTGAGAAAGGA

Downstream 100 bases:

>100_bases
AGTACCGGGTCCGAACAGGGAGTATGAACAAATTGGGAATTATGAATATTACGGCACTGCTGAGATCCGGTAGAGAAAAT
AAAGAAACAATTTTAGAGAT

Product: hypothetical protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; Archaeosine biosynthesis protein queC; PreQ(0) synthase

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKAITLLSSGLDSVAALAIAAESLEIEMAITFDYGQRAGQREMEYSEKVCEHFGIEQRIIKLDWLGEITHTSLVNRDEEV
PSLSFEDIDENSPSMITEYSAKAVWVPNRNGVMLNIAGSFAESRGCDYIVVGFNGEEAGTFPDNSRDYIQAVDNAFSYST
QNGVKVLAPLAEMGKTEIVKKALEAEAPLEYSWSCYHGGEIPCGKCESCVRRARAFKNIGIKDPLLERLGI

Sequences:

>Translated_231_residues
MKAITLLSSGLDSVAALAIAAESLEIEMAITFDYGQRAGQREMEYSEKVCEHFGIEQRIIKLDWLGEITHTSLVNRDEEV
PSLSFEDIDENSPSMITEYSAKAVWVPNRNGVMLNIAGSFAESRGCDYIVVGFNGEEAGTFPDNSRDYIQAVDNAFSYST
QNGVKVLAPLAEMGKTEIVKKALEAEAPLEYSWSCYHGGEIPCGKCESCVRRARAFKNIGIKDPLLERLGI
>Mature_231_residues
MKAITLLSSGLDSVAALAIAAESLEIEMAITFDYGQRAGQREMEYSEKVCEHFGIEQRIIKLDWLGEITHTSLVNRDEEV
PSLSFEDIDENSPSMITEYSAKAVWVPNRNGVMLNIAGSFAESRGCDYIVVGFNGEEAGTFPDNSRDYIQAVDNAFSYST
QNGVKVLAPLAEMGKTEIVKKALEAEAPLEYSWSCYHGGEIPCGKCESCVRRARAFKNIGIKDPLLERLGI

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=229, Percent_Identity=22.707423580786, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_METMA (Q8PYU8)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_632777.1
- ProteinModelPortal:   Q8PYU8
- SMR:   Q8PYU8
- GeneID:   1479095
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_0753
- NMPDR:   fig|192952.1.peg.753
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK812044
- BioCyc:   MMAZ192952:MM0753-MONOMER
- HAMAP:   MF_01633_A
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25460; Mature: 25460

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAITLLSSGLDSVAALAIAAESLEIEMAITFDYGQRAGQREMEYSEKVCEHFGIEQRII
CCHHHHHHCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHEEE
KLDWLGEITHTSLVNRDEEVPSLSFEDIDENSPSMITEYSAKAVWVPNRNGVMLNIAGSF
EEECCCCHHHHHHHCCCCCCCCCCHHCCCCCCCCEEEECCCEEEEECCCCCEEEEECCCH
AESRGCDYIVVGFNGEEAGTFPDNSRDYIQAVDNAFSYSTQNGVKVLAPLAEMGKTEIVK
HHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHH
KALEAEAPLEYSWSCYHGGEIPCGKCESCVRRARAFKNIGIKDPLLERLGI
HHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCC
>Mature Secondary Structure
MKAITLLSSGLDSVAALAIAAESLEIEMAITFDYGQRAGQREMEYSEKVCEHFGIEQRII
CCHHHHHHCCHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHHHHHHHHHCCCHHEEE
KLDWLGEITHTSLVNRDEEVPSLSFEDIDENSPSMITEYSAKAVWVPNRNGVMLNIAGSF
EEECCCCHHHHHHHCCCCCCCCCCHHCCCCCCCCEEEECCCEEEEECCCCCEEEEECCCH
AESRGCDYIVVGFNGEEAGTFPDNSRDYIQAVDNAFSYSTQNGVKVLAPLAEMGKTEIVK
HHHCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHH
KALEAEAPLEYSWSCYHGGEIPCGKCESCVRRARAFKNIGIKDPLLERLGI
HHHHHCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824