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The map label for this gene is ppa [H]

Identifier: 212225066

GI number: 212225066

Start: 1801934

End: 1802470

Strand: Reverse

Name: ppa [H]

Synonym: TON_1914

Alternate gene names: 212225066

Gene position: 1802470-1801934 (Counterclockwise)

Preceding gene: 212225067

Following gene: 212225065

Centisome position: 97.56

GC content: 56.05

Gene sequence:

>537_bases
ATGAACCCGTTCCACGAGCTTGAGCCCGGACCGGAGGTTCCAGAGGTCGTTTACGCTCTTATAGAGATTCCGAAGGGAAG
CAGGAACAAGTACGAGCTCGACAAGAAGACCGGCCTTCTCAAGCTTGATAGAGTGCTCTACAGCCCGTTCTTCTACCCGG
TTGACTACGGAATCATCCCGCAGACCTGGTACGACGACGGCGACCCCTTTGACATAATGGTCATCATGCGCGAGCCGGTC
TACCCGCTCACCATCGTCGAGGCCAGGCCGATAGGCATCATGAAGATGGAGGACAGCGGAGACAAAGACTGGAAGGTTCT
CGCCGTTCCCGTCGAGGATCCGTACTTCAATGACTGGAAGGACATCGACGACGTTCCGAAGGCCTTCCTTGACGAGATAG
CCCACTTCTTCCAGAGGTACAAGGAGCTCCAGGGCAAAGTCACCACCGTCGAAGGCTGGGGCACCGCCGAGGAGGCCAAG
AGGGAAATCCTCAGGGCCATCGAGATGTACAAAGAGAAGTTCGGTAAGAAGGAGTGA

Upstream 100 bases:

>100_bases
TCTCCCCACTGCTTTTTTCTCGGTTTCACAACCAACAACTTTAAAAGCCCTATCCGAAAGCCTAACCTAGAAGTTCTACA
AGGAGTAAGAGGTGGTAAGG

Downstream 100 bases:

>100_bases
TTTCTTTCCTCTTATTCCCTTCACCAAGGAGGTAAAGGCATGTACAAGCTCCTGAAGATTAAGGATGTTGTAAGGATTCC
CCCCCGGATGTTCACCATGG

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MNPFHELEPGPEVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPQTWYDDGDPFDIMVIMREPV
YPLTIVEARPIGIMKMEDSGDKDWKVLAVPVEDPYFNDWKDIDDVPKAFLDEIAHFFQRYKELQGKVTTVEGWGTAEEAK
REILRAIEMYKEKFGKKE

Sequences:

>Translated_178_residues
MNPFHELEPGPEVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPQTWYDDGDPFDIMVIMREPV
YPLTIVEARPIGIMKMEDSGDKDWKVLAVPVEDPYFNDWKDIDDVPKAFLDEIAHFFQRYKELQGKVTTVEGWGTAEEAK
REILRAIEMYKEKFGKKE
>Mature_178_residues
MNPFHELEPGPEVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIPQTWYDDGDPFDIMVIMREPV
YPLTIVEARPIGIMKMEDSGDKDWKVLAVPVEDPYFNDWKDIDDVPKAFLDEIAHFFQRYKELQGKVTTVEGWGTAEEAK
REILRAIEMYKEKFGKKE

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Homo sapiens, GI11056044, Length=172, Percent_Identity=31.3953488372093, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI29171702, Length=153, Percent_Identity=28.1045751633987, Blast_Score=66, Evalue=2e-11,
Organism=Escherichia coli, GI1790673, Length=168, Percent_Identity=41.6666666666667, Blast_Score=133, Evalue=6e-33,
Organism=Caenorhabditis elegans, GI71984889, Length=173, Percent_Identity=26.5895953757225, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984883, Length=173, Percent_Identity=26.5895953757225, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI71984880, Length=173, Percent_Identity=26.5895953757225, Blast_Score=64, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI71984895, Length=173, Percent_Identity=26.5895953757225, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319483, Length=151, Percent_Identity=33.112582781457, Blast_Score=71, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323923, Length=165, Percent_Identity=26.6666666666667, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 20812; Mature: 20812

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPFHELEPGPEVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIP
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECHHHCCHHHHHHHHHCCCCCCCCCCCCC
QTWYDDGDPFDIMVIMREPVYPLTIVEARPIGIMKMEDSGDKDWKVLAVPVEDPYFNDWK
CCCCCCCCCEEEEEEEECCCCCEEEEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCC
DIDDVPKAFLDEIAHFFQRYKELQGKVTTVEGWGTAEEAKREILRAIEMYKEKFGKKE
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNPFHELEPGPEVPEVVYALIEIPKGSRNKYELDKKTGLLKLDRVLYSPFFYPVDYGIIP
CCCCCCCCCCCCHHHHHHHHHHCCCCCCCCEECHHHCCHHHHHHHHHCCCCCCCCCCCCC
QTWYDDGDPFDIMVIMREPVYPLTIVEARPIGIMKMEDSGDKDWKVLAVPVEDPYFNDWK
CCCCCCCCCEEEEEEEECCCCCEEEEECCCCEEEEECCCCCCCEEEEEEECCCCCCCCCC
DIDDVPKAFLDEIAHFFQRYKELQGKVTTVEGWGTAEEAKREILRAIEMYKEKFGKKE
CHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA