Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 212224767

GI number: 212224767

Start: 1476931

End: 1477485

Strand: Reverse

Name: yggV [C]

Synonym: TON_1616

Alternate gene names: 212224767

Gene position: 1477485-1476931 (Counterclockwise)

Preceding gene: 212224768

Following gene: 212224766

Centisome position: 79.97

GC content: 49.55

Gene sequence:

>555_bases
ATGAGGCTGGCGTTCATCACTTCTAACCCGGGGAAGGTTGAGGAAGCGCGAAAGTACTTTGAACCCTTGGGCGTTGAAGT
TTATCAGCTCAAGGTTGAGTATCCAGAGATACAGGCAGATACGCTCGAAGAAGTTGCCCTCTTCGGCTTGGAGTGGCTGA
GCAGGAAAATCGATGAACCGTTTTTCCTCGACGATTCTGGTCTCTTCGTTGAAGCTCTGAAGGGATTCCCTGGTGTTTAC
TCTGCCTACGTCTACAAGACCCTCGGCGTTGACGGCCTTCTGAAGCTCATGGAGGGCGTTGAGAACAGGAGGGCGTACTT
CAAGAGTGTCATAGCTTACTGGGACGGCGAAGCTCACATCTTTACCGGTATTGTGGAAGGCGAGATAATCCACGAGAAGC
GCGGAAACATGGGCTTCGGCTTCGACCCGGTATTCAAGCCTTCGGGTTTCGACAGAACTTTTGCCGAAATGACAACCACC
GAAAAGAACAAAATATCACACAGAGGTCTGGCTCTTAAAGCTTTTTCAGAGTGGCTAAAGGAAAACCTTAAATAA

Upstream 100 bases:

>100_bases
GGAACAGAAAGCTGAGAGGCGTGAACTCGTCGAGAAGATTGGTTACAAAATAGACTGAAAGTTTTTTATCGTCTTTTCTT
CCCTATCCTCCGGTGGTTAT

Downstream 100 bases:

>100_bases
GCTCATCCTCCCAAAAATTATGATTGCAGTTGTACAAGTGACGAAGGGGGTCGCGATGGTAACTTCACTCGATGCCACTG
ATATGAAGCTGTTGAAGGAA

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MRLAFITSNPGKVEEARKYFEPLGVEVYQLKVEYPEIQADTLEEVALFGLEWLSRKIDEPFFLDDSGLFVEALKGFPGVY
SAYVYKTLGVDGLLKLMEGVENRRAYFKSVIAYWDGEAHIFTGIVEGEIIHEKRGNMGFGFDPVFKPSGFDRTFAEMTTT
EKNKISHRGLALKAFSEWLKENLK

Sequences:

>Translated_184_residues
MRLAFITSNPGKVEEARKYFEPLGVEVYQLKVEYPEIQADTLEEVALFGLEWLSRKIDEPFFLDDSGLFVEALKGFPGVY
SAYVYKTLGVDGLLKLMEGVENRRAYFKSVIAYWDGEAHIFTGIVEGEIIHEKRGNMGFGFDPVFKPSGFDRTFAEMTTT
EKNKISHRGLALKAFSEWLKENLK
>Mature_184_residues
MRLAFITSNPGKVEEARKYFEPLGVEVYQLKVEYPEIQADTLEEVALFGLEWLSRKIDEPFFLDDSGLFVEALKGFPGVY
SAYVYKTLGVDGLLKLMEGVENRRAYFKSVIAYWDGEAHIFTGIVEGEIIHEKRGNMGFGFDPVFKPSGFDRTFAEMTTT
EKNKISHRGLALKAFSEWLKENLK

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=182, Percent_Identity=31.3186813186813, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI31657144, Length=152, Percent_Identity=33.5526315789474, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1789324, Length=194, Percent_Identity=32.9896907216495, Blast_Score=85, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17556833, Length=184, Percent_Identity=32.6086956521739, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6322529, Length=193, Percent_Identity=31.0880829015544, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19920712, Length=174, Percent_Identity=39.0804597701149, Blast_Score=121, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21009; Mature: 21009

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLAFITSNPGKVEEARKYFEPLGVEVYQLKVEYPEIQADTLEEVALFGLEWLSRKIDEP
CEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
FFLDDSGLFVEALKGFPGVYSAYVYKTLGVDGLLKLMEGVENRRAYFKSVIAYWDGEAHI
EEECCCCHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FTGIVEGEIIHEKRGNMGFGFDPVFKPSGFDRTFAEMTTTEKNKISHRGLALKAFSEWLK
EEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCHHHHHHHHHH
ENLK
HHCC
>Mature Secondary Structure
MRLAFITSNPGKVEEARKYFEPLGVEVYQLKVEYPEIQADTLEEVALFGLEWLSRKIDEP
CEEEEEECCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCC
FFLDDSGLFVEALKGFPGVYSAYVYKTLGVDGLLKLMEGVENRRAYFKSVIAYWDGEAHI
EEECCCCHHHHHHHCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEE
FTGIVEGEIIHEKRGNMGFGFDPVFKPSGFDRTFAEMTTTEKNKISHRGLALKAFSEWLK
EEEECCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHCCCHHHHHHHHHH
ENLK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA