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The map label for this gene is 212224684

Identifier: 212224684

GI number: 212224684

Start: 1407539

End: 1408015

Strand: Reverse

Name: 212224684

Synonym: TON_1533

Alternate gene names: NA

Gene position: 1408015-1407539 (Counterclockwise)

Preceding gene: 212224685

Following gene: 212224683

Centisome position: 76.21

GC content: 54.51

Gene sequence:

>477_bases
ATGGATGAGTCGTGGAAAAAGGACATAGCATGGATCCTAATCGCGTTCATAGCAGTTTTTGCACTCCAATTCGGGCTTAA
GATGGCCCTTCACACGGACTCGCCGCTGGTCATAGTGGTGAGCGGCTCCATGGAACCCGTCTTTTACAGGGGGGATGTCG
TCCTCCTGAAGGGGATAAGTGAGAACAACATGGATGAAGTTCACGTTGGCGACGTGATCGTCTATAAGCGCCCCGGTTAT
GAATACCCGATAATTCACCGCGTCAGGGAGATAAAGGAGGTAAGCCTTGGAGGGAAAACTGAGAAGTGCTTCGTCACATG
GGGCGACAACAACTGGGCTCCCGACCCCGATTATCCAACGCCTTACGGGCCGGTCCCTTGCGTTCCAGCTTATGCCGTCG
AGGACAAGGCCCTGCTAGTTTTCCCGAAGATAGGCCTCATCCCGCTCGAGATAAGGGAGCGCCTCGGCCTGGGATGA

Upstream 100 bases:

>100_bases
GCTATCATATGGATATAACAGGGAAAAGGGTCAGCCTTGAAACATGCACCGCGATAGGTGCCATACCCGCTAGAATAAGC
ACTCTGATGGAGGCGCTGAG

Downstream 100 bases:

>100_bases
TGTGAGGGTAGGTGGCCGAGAGACCGATGAGGAGCTAATCGGCCCCTGACCATCAAACTTTGCTGGTGCAAAGTTTGATC
AAAGTTCGTAGCTCCTTTTA

Product: signal peptidase I

Products: NA

Alternate protein names: Signal Peptidase; Peptidase; Archaean Signal Peptidase; Signal Sequence Peptidase I; Signal Peptidase Subunit

Number of amino acids: Translated: 158; Mature: 158

Protein sequence:

>158_residues
MDESWKKDIAWILIAFIAVFALQFGLKMALHTDSPLVIVVSGSMEPVFYRGDVVLLKGISENNMDEVHVGDVIVYKRPGY
EYPIIHRVREIKEVSLGGKTEKCFVTWGDNNWAPDPDYPTPYGPVPCVPAYAVEDKALLVFPKIGLIPLEIRERLGLG

Sequences:

>Translated_158_residues
MDESWKKDIAWILIAFIAVFALQFGLKMALHTDSPLVIVVSGSMEPVFYRGDVVLLKGISENNMDEVHVGDVIVYKRPGY
EYPIIHRVREIKEVSLGGKTEKCFVTWGDNNWAPDPDYPTPYGPVPCVPAYAVEDKALLVFPKIGLIPLEIRERLGLG
>Mature_158_residues
MDESWKKDIAWILIAFIAVFALQFGLKMALHTDSPLVIVVSGSMEPVFYRGDVVLLKGISENNMDEVHVGDVIVYKRPGY
EYPIIHRVREIKEVSLGGKTEKCFVTWGDNNWAPDPDYPTPYGPVPCVPAYAVEDKALLVFPKIGLIPLEIRERLGLG

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI7657609, Length=91, Percent_Identity=42.8571428571429, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI15150809, Length=91, Percent_Identity=40.6593406593407, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17510347, Length=97, Percent_Identity=44.3298969072165, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6322213, Length=101, Percent_Identity=39.6039603960396, Blast_Score=67, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21358147, Length=97, Percent_Identity=40.2061855670103, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 17716; Mature: 17716

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDESWKKDIAWILIAFIAVFALQFGLKMALHTDSPLVIVVSGSMEPVFYRGDVVLLKGIS
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCEEEECCEEEEECCC
ENNMDEVHVGDVIVYKRPGYEYPIIHRVREIKEVSLGGKTEKCFVTWGDNNWAPDPDYPT
CCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCC
PYGPVPCVPAYAVEDKALLVFPKIGLIPLEIRERLGLG
CCCCCCCCCCEEECCCEEEEECCCCEEEHHHHHHCCCC
>Mature Secondary Structure
MDESWKKDIAWILIAFIAVFALQFGLKMALHTDSPLVIVVSGSMEPVFYRGDVVLLKGIS
CCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEEECCCCCEEEECCEEEEECCC
ENNMDEVHVGDVIVYKRPGYEYPIIHRVREIKEVSLGGKTEKCFVTWGDNNWAPDPDYPT
CCCCCEEEECCEEEEECCCCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCC
PYGPVPCVPAYAVEDKALLVFPKIGLIPLEIRERLGLG
CCCCCCCCCCEEECCCEEEEECCCCEEEHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA