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The map label for this gene is cobO [H]

Identifier: 212224680

GI number: 212224680

Start: 1402842

End: 1403369

Strand: Reverse

Name: cobO [H]

Synonym: TON_1529

Alternate gene names: 212224680

Gene position: 1403369-1402842 (Counterclockwise)

Preceding gene: 212224683

Following gene: 212224679

Centisome position: 75.96

GC content: 57.58

Gene sequence:

>528_bases
ATGCCTTGGAAAGACAAGCTCGGCTTGGTTCACATCTACACCGGCAACGGGAAGGGAAAAACCACCGCAGCCTTCGGTCT
TGCGGTGAGAATGCTCGGCTCCGGTGGGAAGGTGATAATACTCCAGTTCATGAAGGCCGGGAACGTTTACGGAGAGCAGA
AGAAGATAGCAGAGTGCGGGGCGGTCATAGAGTCCTTTGGGTTACCGAAGTTCGTCCACGGCAAACCCGAGCCCGACGAC
ATAGAAGCTGCCAAGAAAGCCCTTCAGCGCGCGAAGGAAGTTGTCTCGAGCGGAGAGTGGGACTTGGTAATCCTCGATGA
GCTCTGCGTCGCTTTGGGCTTCGGCATGCTCGACGTCGAGGAAGTCAAGGAGCTCATCAAGAGCAAGGCACCCCACACCG
AGCTCGTCATCACCGGCCGCTACTGCCCGGAGGAGCTCTTCGAGTTGGCCGACTACGTCACCGAGATGAGGGAGATAAAG
CACCCTTATCAGAGGGGCATCCTTGCGAGGAGGGGGGTCGAGTACTGA

Upstream 100 bases:

>100_bases
ACCACCTGGAAGGTTATATGAGCAAGAATTTAACCCTTTCTTTAATTTCATGCCAAACTCCTAAAAACCCTGGCGATTAT
ATCCACCCTGGTGAATTCAC

Downstream 100 bases:

>100_bases
TTTTCCTTCTTTAGTTTCGACGTTAACCGAAAAGTTTTTTAGTTAGGAAAGCTTAAGATAACCCGAGGAGATTTTAGTAA
CAATTCTTTAGAAAAGGGGG

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MPWKDKLGLVHIYTGNGKGKTTAAFGLAVRMLGSGGKVIILQFMKAGNVYGEQKKIAECGAVIESFGLPKFVHGKPEPDD
IEAAKKALQRAKEVVSSGEWDLVILDELCVALGFGMLDVEEVKELIKSKAPHTELVITGRYCPEELFELADYVTEMREIK
HPYQRGILARRGVEY

Sequences:

>Translated_175_residues
MPWKDKLGLVHIYTGNGKGKTTAAFGLAVRMLGSGGKVIILQFMKAGNVYGEQKKIAECGAVIESFGLPKFVHGKPEPDD
IEAAKKALQRAKEVVSSGEWDLVILDELCVALGFGMLDVEEVKELIKSKAPHTELVITGRYCPEELFELADYVTEMREIK
HPYQRGILARRGVEY
>Mature_174_residues
PWKDKLGLVHIYTGNGKGKTTAAFGLAVRMLGSGGKVIILQFMKAGNVYGEQKKIAECGAVIESFGLPKFVHGKPEPDDI
EAAKKALQRAKEVVSSGEWDLVILDELCVALGFGMLDVEEVKELIKSKAPHTELVITGRYCPEELFELADYVTEMREIKH
PYQRGILARRGVEY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=172, Percent_Identity=34.8837209302326, Blast_Score=118, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 19366; Mature: 19235

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWKDKLGLVHIYTGNGKGKTTAAFGLAVRMLGSGGKVIILQFMKAGNVYGEQKKIAECG
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHH
AVIESFGLPKFVHGKPEPDDIEAAKKALQRAKEVVSSGEWDLVILDELCVALGFGMLDVE
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCHH
EVKELIKSKAPHTELVITGRYCPEELFELADYVTEMREIKHPYQRGILARRGVEY
HHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCC
>Mature Secondary Structure 
PWKDKLGLVHIYTGNGKGKTTAAFGLAVRMLGSGGKVIILQFMKAGNVYGEQKKIAECG
CCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCCHHHHHHHHH
AVIESFGLPKFVHGKPEPDDIEAAKKALQRAKEVVSSGEWDLVILDELCVALGFGMLDVE
HHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCHH
EVKELIKSKAPHTELVITGRYCPEELFELADYVTEMREIKHPYQRGILARRGVEY
HHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]