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The map label for this gene is 212224668

Identifier: 212224668

GI number: 212224668

Start: 1392845

End: 1394503

Strand: Reverse

Name: 212224668

Synonym: TON_1517

Alternate gene names: NA

Gene position: 1394503-1392845 (Counterclockwise)

Preceding gene: 212224669

Following gene: 212224667

Centisome position: 75.48

GC content: 56.18

Gene sequence:

>1659_bases
GTGTCGGACTTTGGTGTGTTGGCATTGCTGCCCCCATTGGTTGCCATTATCTTAGCCATCTGGACAAAGAGGGTCATCCT
GGCGCTGTTTGCGGGCGTCTGGATTGGTGGAGTGATGGTCGCCGGCGGTAATCCGGTAGTCGGGACCACCCAGACGCTGG
AGTGGATTGTCAGTAGCGTTACAAGCGACTGGAACGCCAGGATACTCATATTTAACTTCCTGATAGGTGCGGGTGTCGGA
CTTATCTACAAGTCCGGCGCAGTCCACGCGCTGGCGGCTTCCCTGGTAAGGAGGGTCAAAAGCAGCAGAGGGGCCTCGAT
CCTCGGATGGATCCTCGGTATACTGGTGTTCTTCGATGACTACACCAACACCATAGTCGTCGGAAACACCATGAGGCCCA
TCACCGACAGGATGAGGGTTTCCAGGGAGATGCTCGCTTACATAGACGACTCTACCGCGGCACCCGTGGCTGGTCTTGCG
CTCGTCTCAACGTGGATAGGCTATGAACTTCTCATGATAGGCAAGGGCTTTGATAACGCCAACATCGTTTATGGAACTTA
TGACGCCTGGCTGTCTAGCGTGCCCTATAGGTTCTATTCGATACTGGCAATAATACTCGTTTTCATCGTTGCATACACCC
ACAGGCACTACGGCCCCATGCTGAAGGCAGAATATCGCGCTAGGACTGAGGGCAAAGTCCTCCGCGACGGTGCGAAGCCC
CTCATGACCACCGAGGTTGACCTAGGCACGCCCAATGAGGGCGGAAGTCTCTGGGACTTCGTTATTCCGCTCCTTGTCCT
CGTTGGCGTCTCCATGCTTGGCCTCTGGTACACCGGAGCGGCCAACCTTGAGGCATATAGTCAGGATCTCGGCTGGTGGA
CCGAGTTGGAGAACCCGTTCGGTGTCAACTTCCTCAACTACAGCTTCATTGAGTCCTTCCGTGAGGCCGACGCTGCCACC
GCGCTTCTCTGGGGCTCCTTCGCAATGGTCGTCGTTGCCAGCATAATGCTTTTGGGCAGGAGGAAAATGACGGTGGAGGA
GTGGGAAGACACAGTAGTCAGGGGAATGAAGCAGATGCTCTTCGCCAACACCATCCTCGTCCTTGCTTGGAGCCTCGGAA
CCGCCGCTGAAAGCGTTGGAACCGGCGACTACGTCATCAGCCTTGCGACCAGCTCTGGGGCGAACCTCGGACCATGGATG
CCGCTGATAATGTTCCTCTCTGCGATGTTCGTTGCGTTTACCACGGGAACTAGCTGGGGAACTTTCGCCATAATGGTTCC
GCTTGGAGTCCAGCTCAGCCTGGCCTTCACCAACGGTCAGGTTAATGAGATAGTCTTCGCCACCATCGGAGCCACGTTTA
CCGGAAGCATCTTCGGCGACCACTGCTCACCCATCAGTGATACCACCATCATGAGCTCCATGTTCAGTGGTTCTGACCAC
ATAGACCACGTCACAACCCAAATACCCTATGCCTTCACGGTTGCGACAATTGGCAGCGTGCTGTACCTCCTGTTCGCCCT
GGGAGTCACGAGCTGGGTTATACTCCTGCCGCTGGGTATAGCCCTCCTCGTCGGTGCGTGGTACGTCCTCAGCGAGTGGT
ACGGCAAGAAGTACGGCATACCGCACGGCAAGGTGCCCATCTACGTTGCCGAGGAGTGA

Upstream 100 bases:

>100_bases
AGAAAATTTTTCGAGAATAAGGCAATACGACAAAGGATATACAGAAAGCTTTATATTCTCTCCGTGTTCCTTTGCATGAA
ACACCTCAGGAGGTGAAAAT

Downstream 100 bases:

>100_bases
TTTCCTCTTTTTCCATCCTTTCCTTCACCAATTTTAAAAACATGAGAGAGCACTCTTCTTGGAGGTGATGGTGATGCTGA
TTAGAGCTTTCGTTCCCGCC

Product: NhaC-type sodium/hydrogen antiporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 552; Mature: 551

Protein sequence:

>552_residues
MSDFGVLALLPPLVAIILAIWTKRVILALFAGVWIGGVMVAGGNPVVGTTQTLEWIVSSVTSDWNARILIFNFLIGAGVG
LIYKSGAVHALAASLVRRVKSSRGASILGWILGILVFFDDYTNTIVVGNTMRPITDRMRVSREMLAYIDDSTAAPVAGLA
LVSTWIGYELLMIGKGFDNANIVYGTYDAWLSSVPYRFYSILAIILVFIVAYTHRHYGPMLKAEYRARTEGKVLRDGAKP
LMTTEVDLGTPNEGGSLWDFVIPLLVLVGVSMLGLWYTGAANLEAYSQDLGWWTELENPFGVNFLNYSFIESFREADAAT
ALLWGSFAMVVVASIMLLGRRKMTVEEWEDTVVRGMKQMLFANTILVLAWSLGTAAESVGTGDYVISLATSSGANLGPWM
PLIMFLSAMFVAFTTGTSWGTFAIMVPLGVQLSLAFTNGQVNEIVFATIGATFTGSIFGDHCSPISDTTIMSSMFSGSDH
IDHVTTQIPYAFTVATIGSVLYLLFALGVTSWVILLPLGIALLVGAWYVLSEWYGKKYGIPHGKVPIYVAEE

Sequences:

>Translated_552_residues
MSDFGVLALLPPLVAIILAIWTKRVILALFAGVWIGGVMVAGGNPVVGTTQTLEWIVSSVTSDWNARILIFNFLIGAGVG
LIYKSGAVHALAASLVRRVKSSRGASILGWILGILVFFDDYTNTIVVGNTMRPITDRMRVSREMLAYIDDSTAAPVAGLA
LVSTWIGYELLMIGKGFDNANIVYGTYDAWLSSVPYRFYSILAIILVFIVAYTHRHYGPMLKAEYRARTEGKVLRDGAKP
LMTTEVDLGTPNEGGSLWDFVIPLLVLVGVSMLGLWYTGAANLEAYSQDLGWWTELENPFGVNFLNYSFIESFREADAAT
ALLWGSFAMVVVASIMLLGRRKMTVEEWEDTVVRGMKQMLFANTILVLAWSLGTAAESVGTGDYVISLATSSGANLGPWM
PLIMFLSAMFVAFTTGTSWGTFAIMVPLGVQLSLAFTNGQVNEIVFATIGATFTGSIFGDHCSPISDTTIMSSMFSGSDH
IDHVTTQIPYAFTVATIGSVLYLLFALGVTSWVILLPLGIALLVGAWYVLSEWYGKKYGIPHGKVPIYVAEE
>Mature_551_residues
SDFGVLALLPPLVAIILAIWTKRVILALFAGVWIGGVMVAGGNPVVGTTQTLEWIVSSVTSDWNARILIFNFLIGAGVGL
IYKSGAVHALAASLVRRVKSSRGASILGWILGILVFFDDYTNTIVVGNTMRPITDRMRVSREMLAYIDDSTAAPVAGLAL
VSTWIGYELLMIGKGFDNANIVYGTYDAWLSSVPYRFYSILAIILVFIVAYTHRHYGPMLKAEYRARTEGKVLRDGAKPL
MTTEVDLGTPNEGGSLWDFVIPLLVLVGVSMLGLWYTGAANLEAYSQDLGWWTELENPFGVNFLNYSFIESFREADAATA
LLWGSFAMVVVASIMLLGRRKMTVEEWEDTVVRGMKQMLFANTILVLAWSLGTAAESVGTGDYVISLATSSGANLGPWMP
LIMFLSAMFVAFTTGTSWGTFAIMVPLGVQLSLAFTNGQVNEIVFATIGATFTGSIFGDHCSPISDTTIMSSMFSGSDHI
DHVTTQIPYAFTVATIGSVLYLLFALGVTSWVILLPLGIALLVGAWYVLSEWYGKKYGIPHGKVPIYVAEE

Specific function: Unknown

COG id: COG1757

COG function: function code C; Na+/H+ antiporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018461 [H]

Pfam domain/function: PF03553 Na_H_antiporter [H]

EC number: NA

Molecular weight: Translated: 59958; Mature: 59826

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFGVLALLPPLVAIILAIWTKRVILALFAGVWIGGVMVAGGNPVVGTTQTLEWIVSSV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHH
TSDWNARILIFNFLIGAGVGLIYKSGAVHALAASLVRRVKSSRGASILGWILGILVFFDD
CCCCCCEEHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
YTNTIVVGNTMRPITDRMRVSREMLAYIDDSTAAPVAGLALVSTWIGYELLMIGKGFDNA
CCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCC
NIVYGTYDAWLSSVPYRFYSILAIILVFIVAYTHRHYGPMLKAEYRARTEGKVLRDGAKP
CEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHCCCCC
LMTTEVDLGTPNEGGSLWDFVIPLLVLVGVSMLGLWYTGAANLEAYSQDLGWWTELENPF
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHCCCCC
GVNFLNYSFIESFREADAATALLWGSFAMVVVASIMLLGRRKMTVEEWEDTVVRGMKQML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
FANTILVLAWSLGTAAESVGTGDYVISLATSSGANLGPWMPLIMFLSAMFVAFTTGTSWG
HHHHHHHHHHHHCHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
TFAIMVPLGVQLSLAFTNGQVNEIVFATIGATFTGSIFGDHCSPISDTTIMSSMFSGSDH
EEEEEEECCCEEEEEEECCCCCEEEEEEECCHHCCCCCCCCCCCCCHHHHHHHHHCCCCC
IDHVTTQIPYAFTVATIGSVLYLLFALGVTSWVILLPLGIALLVGAWYVLSEWYGKKYGI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PHGKVPIYVAEE
CCCCCCEEEECC
>Mature Secondary Structure 
SDFGVLALLPPLVAIILAIWTKRVILALFAGVWIGGVMVAGGNPVVGTTQTLEWIVSSV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHHHHHHHHH
TSDWNARILIFNFLIGAGVGLIYKSGAVHALAASLVRRVKSSRGASILGWILGILVFFDD
CCCCCCEEHHHHHHHHCCHHHEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHC
YTNTIVVGNTMRPITDRMRVSREMLAYIDDSTAAPVAGLALVSTWIGYELLMIGKGFDNA
CCCEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEEEEEECCCCCC
NIVYGTYDAWLSSVPYRFYSILAIILVFIVAYTHRHYGPMLKAEYRARTEGKVLRDGAKP
CEEEECHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHCCCCC
LMTTEVDLGTPNEGGSLWDFVIPLLVLVGVSMLGLWYTGAANLEAYSQDLGWWTELENPF
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHCCCCC
GVNFLNYSFIESFREADAATALLWGSFAMVVVASIMLLGRRKMTVEEWEDTVVRGMKQML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
FANTILVLAWSLGTAAESVGTGDYVISLATSSGANLGPWMPLIMFLSAMFVAFTTGTSWG
HHHHHHHHHHHHCHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCC
TFAIMVPLGVQLSLAFTNGQVNEIVFATIGATFTGSIFGDHCSPISDTTIMSSMFSGSDH
EEEEEEECCCEEEEEEECCCCCEEEEEEECCHHCCCCCCCCCCCCCHHHHHHHHHCCCCC
IDHVTTQIPYAFTVATIGSVLYLLFALGVTSWVILLPLGIALLVGAWYVLSEWYGKKYGI
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PHGKVPIYVAEE
CCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]