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The map label for this gene is soxB [H]

Identifier: 212224430

GI number: 212224430

Start: 1165050

End: 1166210

Strand: Reverse

Name: soxB [H]

Synonym: TON_1281

Alternate gene names: 212224430

Gene position: 1166210-1165050 (Counterclockwise)

Preceding gene: 212224431

Following gene: 212224429

Centisome position: 63.12

GC content: 54.87

Gene sequence:

>1161_bases
ATGCCGACGAAAGAACTTCCCGAAAGAAGCGAAATCGTTATCATCGGCGGGGGAATAATAGGTGTGACCCTTGCCCACGA
GCTAGCTAAACGCGGTGAGGAGGTCACCGTCATAGAGAAGCGCTTCGTAGGCTCAGGCTCGACCTTCCGTTGTGGAACTG
GCATAAGGCAGCAGTTCAACGACGAGGCCAACGTTCAGGTCATGAAGCGCTCCGTCGAGCTCTGGAAGCACTATAGTGAA
GAGTACGGCTTCTCCTTCGAGCAGACAGGCTATCTCTTTTTGCTCTACGACGATGATGAGGTCGAGGAGTTCAAGAGGAA
CATAGCCATCCAGAACCGCTTCGGCGTCCCGACGAGGCTCATAACTCCAGAAGAGGCGAAGGAGATAGTCCCGCTCCTTG
ACATAAGTGAGGTCATAGCGGCATCGTGGAACCCCACTGATGGAAAGGTCGATCCCTTCTACTCGACCGCTGCATTCGCC
CTCAACGCCGAGCGCTTTGGGGCTAAGCTGGTTGAGTACACGGAGGTCAAGGATTTCATCATCGAGAACGGTGAGATAAA
GGGTCTCAAGACCAACAGGGGAGTTATCAAGACGGGCATCGTCGTTAACGCCACCAACGCGTGGGCCAAGCTCATCAACG
CAATGGCCGGAATAAAGACTCCTATTCCGATAGAGCCTTACAAACATCAGGCGGTGATAACGCAGCCGATAAGGAAGGGC
GCGATAAAGCCGATGGTCATTTCCTTCAAGTACGGCCACGCTTATCTGACCCAGACCAGCCACGGCGGCGTTGTTGGCGG
TGTCGGCTACGAGCTGGGGCCAACCTACGACCTCAATCCGACCTATGAGTTCATGCGCGAGGTGAGCTACTACTTCACCA
GGATAATCCCGGCCCTGAGGGAGCTTCTTATACTCAGAACATGGGCGGGCTACTACGCTAAAACGCCTGATAGCAACCCT
GCTATAGGAAAAATCGAGGAGCTGAACGACTACTACATTGCCGCCGGCTTTTCCGGCCACGGCTTCATGATGGCCCCGGC
CGTTGCGGAGATGGTCGCCGATTTGATAACCAAAGGCAGAACGAGCCTTCCAGTCGAGTGGTATGACCCATACAGATTTG
AGCGTGGTGAGCTCAGGGGCCAAGCCCTCCAGATGGGGTGA

Upstream 100 bases:

>100_bases
GAGGGCCAACCTGGACATGGCGAAAATTGACCTGCCGGTAGCGAGACCGCCGCTCAAGAACGTGAAGATGAAGGTTACCG
CCGCTGGGGGATGATGGCTT

Downstream 100 bases:

>100_bases
AGTCCTTTCTTTTTCCTTCGCTATCCTTAAATATCTTCTCGCCGAATTTTCGTGGGTGAAATCATGTATCGCGTTGATTC
TCCCGGTCGGGTGAATCTTA

Product: sarcosine oxidase, beta subunit

Products: NA

Alternate protein names: Sarcosine oxidase subunit B [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MPTKELPERSEIVIIGGGIIGVTLAHELAKRGEEVTVIEKRFVGSGSTFRCGTGIRQQFNDEANVQVMKRSVELWKHYSE
EYGFSFEQTGYLFLLYDDDEVEEFKRNIAIQNRFGVPTRLITPEEAKEIVPLLDISEVIAASWNPTDGKVDPFYSTAAFA
LNAERFGAKLVEYTEVKDFIIENGEIKGLKTNRGVIKTGIVVNATNAWAKLINAMAGIKTPIPIEPYKHQAVITQPIRKG
AIKPMVISFKYGHAYLTQTSHGGVVGGVGYELGPTYDLNPTYEFMREVSYYFTRIIPALRELLILRTWAGYYAKTPDSNP
AIGKIEELNDYYIAAGFSGHGFMMAPAVAEMVADLITKGRTSLPVEWYDPYRFERGELRGQALQMG

Sequences:

>Translated_386_residues
MPTKELPERSEIVIIGGGIIGVTLAHELAKRGEEVTVIEKRFVGSGSTFRCGTGIRQQFNDEANVQVMKRSVELWKHYSE
EYGFSFEQTGYLFLLYDDDEVEEFKRNIAIQNRFGVPTRLITPEEAKEIVPLLDISEVIAASWNPTDGKVDPFYSTAAFA
LNAERFGAKLVEYTEVKDFIIENGEIKGLKTNRGVIKTGIVVNATNAWAKLINAMAGIKTPIPIEPYKHQAVITQPIRKG
AIKPMVISFKYGHAYLTQTSHGGVVGGVGYELGPTYDLNPTYEFMREVSYYFTRIIPALRELLILRTWAGYYAKTPDSNP
AIGKIEELNDYYIAAGFSGHGFMMAPAVAEMVADLITKGRTSLPVEWYDPYRFERGELRGQALQMG
>Mature_385_residues
PTKELPERSEIVIIGGGIIGVTLAHELAKRGEEVTVIEKRFVGSGSTFRCGTGIRQQFNDEANVQVMKRSVELWKHYSEE
YGFSFEQTGYLFLLYDDDEVEEFKRNIAIQNRFGVPTRLITPEEAKEIVPLLDISEVIAASWNPTDGKVDPFYSTAAFAL
NAERFGAKLVEYTEVKDFIIENGEIKGLKTNRGVIKTGIVVNATNAWAKLINAMAGIKTPIPIEPYKHQAVITQPIRKGA
IKPMVISFKYGHAYLTQTSHGGVVGGVGYELGPTYDLNPTYEFMREVSYYFTRIIPALRELLILRTWAGYYAKTPDSNPA
IGKIEELNDYYIAAGFSGHGFMMAPAVAEMVADLITKGRTSLPVEWYDPYRFERGELRGQALQMG

Specific function: Catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10- methylenetetrahydrofolate [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the soxB family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=395, Percent_Identity=29.620253164557, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI197927446, Length=399, Percent_Identity=26.8170426065163, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI21361378, Length=399, Percent_Identity=26.8170426065163, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI194306651, Length=385, Percent_Identity=23.8961038961039, Blast_Score=115, Evalue=6e-26,
Organism=Homo sapiens, GI8923708, Length=375, Percent_Identity=23.7333333333333, Blast_Score=97, Evalue=2e-20,
Organism=Escherichia coli, GI1787438, Length=425, Percent_Identity=23.7647058823529, Blast_Score=73, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI32563613, Length=377, Percent_Identity=23.342175066313, Blast_Score=98, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI17541536, Length=413, Percent_Identity=25.90799031477, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71994045, Length=391, Percent_Identity=22.5063938618926, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994052, Length=398, Percent_Identity=22.3618090452261, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI20130091, Length=401, Percent_Identity=25.9351620947631, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28571104, Length=386, Percent_Identity=25.1295336787565, Blast_Score=136, Evalue=3e-32,
Organism=Drosophila melanogaster, GI20129729, Length=393, Percent_Identity=24.9363867684478, Blast_Score=88, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17985989, Length=372, Percent_Identity=23.6559139784946, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR006278 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.5.3.1 [H]

Molecular weight: Translated: 43193; Mature: 43062

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTKELPERSEIVIIGGGIIGVTLAHELAKRGEEVTVIEKRFVGSGSTFRCGTGIRQQFN
CCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCEECCCCHHHHCC
DEANVQVMKRSVELWKHYSEEYGFSFEQTGYLFLLYDDDEVEEFKRNIAIQNRFGVPTRL
CCCHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHCEEECCCCCCEEE
ITPEEAKEIVPLLDISEVIAASWNPTDGKVDPFYSTAAFALNAERFGAKLVEYTEVKDFI
ECHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHEEECHHHHHHHHHHHHHHHHHH
IENGEIKGLKTNRGVIKTGIVVNATNAWAKLINAMAGIKTPIPIEPYKHQAVITQPIRKG
CCCCEEEEEECCCCEEEECEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
AIKPMVISFKYGHAYLTQTSHGGVVGGVGYELGPTYDLNPTYEFMREVSYYFTRIIPALR
CCCEEEEEEEECCEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ELLILRTWAGYYAKTPDSNPAIGKIEELNDYYIAAGFSGHGFMMAPAVAEMVADLITKGR
HHHHHHHHCCCEECCCCCCCCCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
TSLPVEWYDPYRFERGELRGQALQMG
CCCCEEECCCCCCCCHHCCCEEECCC
>Mature Secondary Structure 
PTKELPERSEIVIIGGGIIGVTLAHELAKRGEEVTVIEKRFVGSGSTFRCGTGIRQQFN
CCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCEEEEEEHHHCCCCCCEECCCCHHHHCC
DEANVQVMKRSVELWKHYSEEYGFSFEQTGYLFLLYDDDEVEEFKRNIAIQNRFGVPTRL
CCCHHHHHHHHHHHHHHHHHHHCCCEECCCEEEEEECCCHHHHHHHHCEEECCCCCCEEE
ITPEEAKEIVPLLDISEVIAASWNPTDGKVDPFYSTAAFALNAERFGAKLVEYTEVKDFI
ECHHHHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCHHHEEECHHHHHHHHHHHHHHHHHH
IENGEIKGLKTNRGVIKTGIVVNATNAWAKLINAMAGIKTPIPIEPYKHQAVITQPIRKG
CCCCEEEEEECCCCEEEECEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHC
AIKPMVISFKYGHAYLTQTSHGGVVGGVGYELGPTYDLNPTYEFMREVSYYFTRIIPALR
CCCEEEEEEEECCEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
ELLILRTWAGYYAKTPDSNPAIGKIEELNDYYIAAGFSGHGFMMAPAVAEMVADLITKGR
HHHHHHHHCCCEECCCCCCCCCCCCEECCCEEEEEEECCCCCCHHHHHHHHHHHHHHCCC
TSLPVEWYDPYRFERGELRGQALQMG
CCCCEEECCCCCCCCHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7543100; 1939012; 3202887; 7692961 [H]