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The map label for this gene is ttuD [H]

Identifier: 212224377

GI number: 212224377

Start: 1120516

End: 1121835

Strand: Reverse

Name: ttuD [H]

Synonym: TON_1228

Alternate gene names: 212224377

Gene position: 1121835-1120516 (Counterclockwise)

Preceding gene: 212224378

Following gene: 212224376

Centisome position: 60.72

GC content: 53.11

Gene sequence:

>1320_bases
ATGATGATTGGAGACACCAAGACCATCGCCTTCGAAATAATGAACGCCGCCCTCAAAGCGGCTGATCCTTATATGGCAGT
GAAAAACTCCTTCGGCTTTGATGGGGAGTGGCTGATTGTTAAAGAGGAGAAATTTAGGGTTTCTGGAAAAATTTACCTCC
TCGCTTTCGGCAAGGCTGCCTGTGCGATGGCTAAAGCTGCTTATGAGGTTCTCGGTGAGAAGATAGCAGAAGGCCTCATC
GTCACAAAATATGGATACGCTGCAAATTGCGTGGACGACTCGAAAATTACGGTAATCGAGGCGGGTCATCCAGTTCCCGA
CGAGAACTCTATGAGAGGCGCACTGGCTGGCGTTGAGCTCGCGGAAAAAGTTGGGGAAGAGGATTTACTTCTTGTCCTGA
TTTCAGGTGGAGGTTCGGCTCTCTTTACTCTACCCGAGGACGGCATAAGCCTTGACGACAAGATACAGACGAACGAGCTT
CTTTTGAAAAGTGGGGCGAAGATTTACGAGATAAACACCGTTAGGAAGCACATCTCAAAGGTGAAGGGCGGAAAACTGGC
AAAGCTTGTGAAGGGGACGGTTGTAAGTTTAATCCTCTCGGATGTCGTCGGTGACCCCTTGGAGGCCATAGCCTCTGGAC
CAACTGTGAGTGACCCCACAACCTTTGAAGACGCTCACAGGGTTCTGAGGCTCTACGGTGTGTGGGACAAGCTCCCGGAG
AGTGTTAGGAAGCACATAGAAAAAGGCCTCCGGGGGGAAGCAGAGGAGACCCTCAAAGAAGATCTGCCCAACGTTCACAA
CTTCATAGTGGGGAGCGGGGCTATAGCGTGTGAGGCCGCAAAGAGAAAGGCCGAAGAGCTCGGTTTTAATGCCCACATCC
TGACGACCACCCTTGAAGGCAAGGCAAGGGAGGTAGCGCTCGCAATCGGCTCGCTGATTCAGGAGATAGCCTCGAGAAAC
CGGCCCTTTGAGAGGCCCGCTGTTCTGATAGCCGGTGGTGAGTGGACAGTCACGATTGAAGGGGAAGCTGGTCTCGGCGG
CCCGAACCAGGAGTTCGCGCTGAGCATAGCGAGGAAGATAGCTGGCTTAAACGCCGTAGTTTTGGCTCTTGACACCGACG
GAACCGACGGTCCCACCGATGCCTCCGGGGGAATTGTTGACGGATCCACCCTTGAAAATCTCAAAACGGCTGGAATAGGT
GTGGAGGAAGTCCTTAAGAAACACGACGTCTACAGGGCCCTCGAAAAAGTAGGTGCGCTCCTCAAAACCGGCCCGACCGG
AACGAACGTCAACTCGCTGGTGATAGCGGTGATTCCGTAG

Upstream 100 bases:

>100_bases
TAAGGATCTCAAGGCCTGGGGTTACGACCTCCACCTCGGAACGATAGAAGGCGAAAGTGCTTACTTTGTCTCAAAGGCTG
GCCGGTTGCGGGGGAAGGAA

Downstream 100 bases:

>100_bases
AAGATATAAATCCTTCTGCTGAACTCTAGAAGGGTGAAATCATGAACCGTATATCTCGAAGGGAGCTGATAAGAAAGGCT
TGGCATATCTCACCGGGAAT

Product: glycerate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MMIGDTKTIAFEIMNAALKAADPYMAVKNSFGFDGEWLIVKEEKFRVSGKIYLLAFGKAACAMAKAAYEVLGEKIAEGLI
VTKYGYAANCVDDSKITVIEAGHPVPDENSMRGALAGVELAEKVGEEDLLLVLISGGGSALFTLPEDGISLDDKIQTNEL
LLKSGAKIYEINTVRKHISKVKGGKLAKLVKGTVVSLILSDVVGDPLEAIASGPTVSDPTTFEDAHRVLRLYGVWDKLPE
SVRKHIEKGLRGEAEETLKEDLPNVHNFIVGSGAIACEAAKRKAEELGFNAHILTTTLEGKAREVALAIGSLIQEIASRN
RPFERPAVLIAGGEWTVTIEGEAGLGGPNQEFALSIARKIAGLNAVVLALDTDGTDGPTDASGGIVDGSTLENLKTAGIG
VEEVLKKHDVYRALEKVGALLKTGPTGTNVNSLVIAVIP

Sequences:

>Translated_439_residues
MMIGDTKTIAFEIMNAALKAADPYMAVKNSFGFDGEWLIVKEEKFRVSGKIYLLAFGKAACAMAKAAYEVLGEKIAEGLI
VTKYGYAANCVDDSKITVIEAGHPVPDENSMRGALAGVELAEKVGEEDLLLVLISGGGSALFTLPEDGISLDDKIQTNEL
LLKSGAKIYEINTVRKHISKVKGGKLAKLVKGTVVSLILSDVVGDPLEAIASGPTVSDPTTFEDAHRVLRLYGVWDKLPE
SVRKHIEKGLRGEAEETLKEDLPNVHNFIVGSGAIACEAAKRKAEELGFNAHILTTTLEGKAREVALAIGSLIQEIASRN
RPFERPAVLIAGGEWTVTIEGEAGLGGPNQEFALSIARKIAGLNAVVLALDTDGTDGPTDASGGIVDGSTLENLKTAGIG
VEEVLKKHDVYRALEKVGALLKTGPTGTNVNSLVIAVIP
>Mature_439_residues
MMIGDTKTIAFEIMNAALKAADPYMAVKNSFGFDGEWLIVKEEKFRVSGKIYLLAFGKAACAMAKAAYEVLGEKIAEGLI
VTKYGYAANCVDDSKITVIEAGHPVPDENSMRGALAGVELAEKVGEEDLLLVLISGGGSALFTLPEDGISLDDKIQTNEL
LLKSGAKIYEINTVRKHISKVKGGKLAKLVKGTVVSLILSDVVGDPLEAIASGPTVSDPTTFEDAHRVLRLYGVWDKLPE
SVRKHIEKGLRGEAEETLKEDLPNVHNFIVGSGAIACEAAKRKAEELGFNAHILTTTLEGKAREVALAIGSLIQEIASRN
RPFERPAVLIAGGEWTVTIEGEAGLGGPNQEFALSIARKIAGLNAVVLALDTDGTDGPTDASGGIVDGSTLENLKTAGIG
VEEVLKKHDVYRALEKVGALLKTGPTGTNVNSLVIAVIP

Specific function: Degrades an unidentified toxic product from the first step of tartrate degradation [H]

COG id: COG2379

COG function: function code G; Putative glycerate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI31543063, Length=479, Percent_Identity=34.0292275574113, Blast_Score=226, Evalue=4e-59,
Organism=Homo sapiens, GI222418771, Length=141, Percent_Identity=34.7517730496454, Blast_Score=72, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193205461, Length=458, Percent_Identity=32.7510917030568, Blast_Score=194, Evalue=6e-50,
Organism=Drosophila melanogaster, GI19920578, Length=442, Percent_Identity=34.841628959276, Blast_Score=199, Evalue=4e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007835 [H]

Pfam domain/function: PF05161 MOFRL [H]

EC number: =1.1.1.81 [H]

Molecular weight: Translated: 46422; Mature: 46422

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIGDTKTIAFEIMNAALKAADPYMAVKNSFGFDGEWLIVKEEKFRVSGKIYLLAFGKAA
CCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEECCCEEECCEEEEEEECHHH
CAMAKAAYEVLGEKIAEGLIVTKYGYAANCVDDSKITVIEAGHPVPDENSMRGALAGVEL
HHHHHHHHHHHHHHHHCCEEEEECCCEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
AEKVGEEDLLLVLISGGGSALFTLPEDGISLDDKIQTNELLLKSGAKIYEINTVRKHISK
HHHCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHH
VKGGKLAKLVKGTVVSLILSDVVGDPLEAIASGPTVSDPTTFEDAHRVLRLYGVWDKLPE
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SVRKHIEKGLRGEAEETLKEDLPNVHNFIVGSGAIACEAAKRKAEELGFNAHILTTTLEG
HHHHHHHHCCCCCHHHHHHHHCCHHHHHEECCCCHHHHHHHHHHHHCCCCEEEEEEECCC
KAREVALAIGSLIQEIASRNRPFERPAVLIAGGEWTVTIEGEAGLGGPNQEFALSIARKI
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHH
AGLNAVVLALDTDGTDGPTDASGGIVDGSTLENLKTAGIGVEEVLKKHDVYRALEKVGAL
CCCCEEEEEEECCCCCCCCCCCCCEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LKTGPTGTNVNSLVIAVIP
HHCCCCCCCCCEEEEEEEC
>Mature Secondary Structure
MMIGDTKTIAFEIMNAALKAADPYMAVKNSFGFDGEWLIVKEEKFRVSGKIYLLAFGKAA
CCCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCEEEEEECCCEEECCEEEEEEECHHH
CAMAKAAYEVLGEKIAEGLIVTKYGYAANCVDDSKITVIEAGHPVPDENSMRGALAGVEL
HHHHHHHHHHHHHHHHCCEEEEECCCEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHH
AEKVGEEDLLLVLISGGGSALFTLPEDGISLDDKIQTNELLLKSGAKIYEINTVRKHISK
HHHCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEHHHHHHHHHH
VKGGKLAKLVKGTVVSLILSDVVGDPLEAIASGPTVSDPTTFEDAHRVLRLYGVWDKLPE
CCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
SVRKHIEKGLRGEAEETLKEDLPNVHNFIVGSGAIACEAAKRKAEELGFNAHILTTTLEG
HHHHHHHHCCCCCHHHHHHHHCCHHHHHEECCCCHHHHHHHHHHHHCCCCEEEEEEECCC
KAREVALAIGSLIQEIASRNRPFERPAVLIAGGEWTVTIEGEAGLGGPNQEFALSIARKI
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCEEEEEEECCCCCCCCCHHHHHHHHHHH
AGLNAVVLALDTDGTDGPTDASGGIVDGSTLENLKTAGIGVEEVLKKHDVYRALEKVGAL
CCCCEEEEEEECCCCCCCCCCCCCEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
LKTGPTGTNVNSLVIAVIP
HHCCCCCCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]