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The map label for this gene is 212224082

Identifier: 212224082

GI number: 212224082

Start: 858797

End: 859315

Strand: Reverse

Name: 212224082

Synonym: TON_0933

Alternate gene names: NA

Gene position: 859315-858797 (Counterclockwise)

Preceding gene: 212224084

Following gene: 212224078

Centisome position: 46.51

GC content: 52.6

Gene sequence:

>519_bases
ATGAGGATATTCATAACCGGCCCGGCAGGAGTTGGGAAGACAACGCTTGTGAGCAGAGTTGCTAGGGAAGTCGACCGCTG
GGGCTACATCGTCGGCGGCATGATAACTCAGGAGGTTCGCCAGCGTGGGAGGAGGATGGGATTTAAAATCACTGCCCTCG
ACACGGGCGAGGAGGGAACTCTCGCGTGGATAGGCAACGGAAGGCCGAGGATAGGAAAATACGTAGTCCATGTTGACGAG
CTCAATCGCGTTGGCGTTTCCGCGATAAGGAGAGCTTTAATTGAGGCCGACCTAATCGTCATAGATGAAATCGGCCCGAT
GGAGTACATGAGCGACGAGTTTGTAAGGGTTGTTGGAGAAGCCCTGAGGTCAGAAAAGCCTCTTCTGGCGGTTGTTCACA
GACGCTTTGTGGACAAGTTCAGGCCGCTTGGAAAACTCTACACACTGAGCGTCGAGAACAGAAACAGAGTCTTCACTGGG
GTAATGGATGAAGTTATGAAAGAGCTAAGGGGCGGTTAA

Upstream 100 bases:

>100_bases
CCTCGGTAGCCTCGTGAGCTCTTCCGGTTTATACTTCAGCTCCATCACGACCACCCTAAAGGGTTTAAGGAGGAAGCTTA
AAACTCGTTCGGTGGTGACA

Downstream 100 bases:

>100_bases
AGGTTCAAGGAGTCCTTGCAGCTCTCGCAGATCCACTTCTCGCCGCCCTCAATGTAGACTTTGTAGAGCGAACCGTACTG
ACCACAGAGCTCGCAGATTC

Product: putative NTPase

Products: NA

Alternate protein names: NTPase THEP1; Nucleoside triphosphate phosphohydrolase [H]

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MRIFITGPAGVGKTTLVSRVAREVDRWGYIVGGMITQEVRQRGRRMGFKITALDTGEEGTLAWIGNGRPRIGKYVVHVDE
LNRVGVSAIRRALIEADLIVIDEIGPMEYMSDEFVRVVGEALRSEKPLLAVVHRRFVDKFRPLGKLYTLSVENRNRVFTG
VMDEVMKELRGG

Sequences:

>Translated_172_residues
MRIFITGPAGVGKTTLVSRVAREVDRWGYIVGGMITQEVRQRGRRMGFKITALDTGEEGTLAWIGNGRPRIGKYVVHVDE
LNRVGVSAIRRALIEADLIVIDEIGPMEYMSDEFVRVVGEALRSEKPLLAVVHRRFVDKFRPLGKLYTLSVENRNRVFTG
VMDEVMKELRGG
>Mature_172_residues
MRIFITGPAGVGKTTLVSRVAREVDRWGYIVGGMITQEVRQRGRRMGFKITALDTGEEGTLAWIGNGRPRIGKYVVHVDE
LNRVGVSAIRRALIEADLIVIDEIGPMEYMSDEFVRVVGEALRSEKPLLAVVHRRFVDKFRPLGKLYTLSVENRNRVFTG
VMDEVMKELRGG

Specific function: Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency [H]

COG id: COG1618

COG function: function code F; Predicted nucleotide kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the THEP1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI14150100, Length=188, Percent_Identity=31.9148936170213, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI85726488, Length=181, Percent_Identity=30.939226519337, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004948 [H]

Pfam domain/function: PF03266 DUF265 [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 19359; Mature: 19359

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFITGPAGVGKTTLVSRVAREVDRWGYIVGGMITQEVRQRGRRMGFKITALDTGEEGT
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
LAWIGNGRPRIGKYVVHVDELNRVGVSAIRRALIEADLIVIDEIGPMEYMSDEFVRVVGE
EEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHH
ALRSEKPLLAVVHRRFVDKFRPLGKLYTLSVENRNRVFTGVMDEVMKELRGG
HHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIFITGPAGVGKTTLVSRVAREVDRWGYIVGGMITQEVRQRGRRMGFKITALDTGEEGT
CEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
LAWIGNGRPRIGKYVVHVDELNRVGVSAIRRALIEADLIVIDEIGPMEYMSDEFVRVVGE
EEEECCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCEEEEECCCCHHHHHHHHHHHHHH
ALRSEKPLLAVVHRRFVDKFRPLGKLYTLSVENRNRVFTGVMDEVMKELRGG
HHHCCCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA