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The map label for this gene is queD [H]

Identifier: 212224076

GI number: 212224076

Start: 853085

End: 853543

Strand: Reverse

Name: queD [H]

Synonym: TON_0927

Alternate gene names: 212224076

Gene position: 853543-853085 (Counterclockwise)

Preceding gene: 212224078

Following gene: 212224074

Centisome position: 46.2

GC content: 48.8

Gene sequence:

>459_bases
ATGGGATTTCGTTTAACTGAGAGAAAGATCGGCTGGCACAAGGACTTCGATAGCTCGCACTTCCTCGCTCTTCCATACGA
AAGCAAGTGCCTTAGAATTCACGGTCACACCTACAACGTTGACGTGGAGATATGGGGCGATGTCAATGAAAGCGGTATGA
TATTCGACTTCAACCACCTCAGCAATCTCATTAAGCTCCTGGACCACAGGATTCTCGTGAGCGAGGAGTGGGTTATAGAA
AGAAAAAACGGTCTGGTAGTTATCGAAAAGAACGGCAAGCGTCTGGAGCTTCCCGAGAACGAAGCAGTCGTCCTTGACAA
GCCCAACGTTACTGCGGAATACATAGCCGAGTGGTTCGCGGAGAGGATAGCTGAAAAAGCTGGGAACAACGTGAGAAAGA
TAAGAGTGAAAATCTGGGAAGACCCGAGGAGCTACGCAGAAGTAACACTGGAGCGTTAG

Upstream 100 bases:

>100_bases
TCAATGGCCTTAATGTAGCCCTGGTTTATAGGTTTTCCTATCCCAAAGCTGCTCAGTAATTGTTATAACCAATTTGCTCT
ACTCGGAAGTGGTGGGAAAA

Downstream 100 bases:

>100_bases
CAGGGATTCTTTCTTTTCTTCTCTGGCACGGGTGTCTCGATACTGCATTTTTCCCTCAGGTCTCTGAGGTGTTTTGCCGC
CGTTGCTGCCAGCTCCTGGA

Product: 6-pyruvoyl-tetrahydropterin synthase-related protein

Products: NA

Alternate protein names: CPH4 synthase; Archaeosine biosynthesis protein queD [H]

Number of amino acids: Translated: 152; Mature: 151

Protein sequence:

>152_residues
MGFRLTERKIGWHKDFDSSHFLALPYESKCLRIHGHTYNVDVEIWGDVNESGMIFDFNHLSNLIKLLDHRILVSEEWVIE
RKNGLVVIEKNGKRLELPENEAVVLDKPNVTAEYIAEWFAERIAEKAGNNVRKIRVKIWEDPRSYAEVTLER

Sequences:

>Translated_152_residues
MGFRLTERKIGWHKDFDSSHFLALPYESKCLRIHGHTYNVDVEIWGDVNESGMIFDFNHLSNLIKLLDHRILVSEEWVIE
RKNGLVVIEKNGKRLELPENEAVVLDKPNVTAEYIAEWFAERIAEKAGNNVRKIRVKIWEDPRSYAEVTLER
>Mature_151_residues
GFRLTERKIGWHKDFDSSHFLALPYESKCLRIHGHTYNVDVEIWGDVNESGMIFDFNHLSNLIKLLDHRILVSEEWVIER
KNGLVVIEKNGKRLELPENEAVVLDKPNVTAEYIAEWFAERIAEKAGNNVRKIRVKIWEDPRSYAEVTLER

Specific function: Catalyzes the conversion of 7,8-dihydroneopterin triphosphate (H2NTP) to 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) and acetaldehyde [H]

COG id: COG0720

COG function: function code H; 6-pyruvoyl-tetrahydropterin synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PTPS family. QueD subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007115 [H]

Pfam domain/function: PF01242 PTPS [H]

EC number: NA

Molecular weight: Translated: 17846; Mature: 17714

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFRLTERKIGWHKDFDSSHFLALPYESKCLRIHGHTYNVDVEIWGDVNESGMIFDFNHL
CCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCEEEEEEEEECCCCCCCEEEEHHHH
SNLIKLLDHRILVSEEWVIERKNGLVVIEKNGKRLELPENEAVVLDKPNVTAEYIAEWFA
HHHHHHHHCEEEECCCEEEECCCCEEEEECCCCEEECCCCCEEEEECCCCCHHHHHHHHH
ERIAEKAGNNVRKIRVKIWEDPRSYAEVTLER
HHHHHHHCCCEEEEEEEEECCCCCEEEEEECC
>Mature Secondary Structure 
GFRLTERKIGWHKDFDSSHFLALPYESKCLRIHGHTYNVDVEIWGDVNESGMIFDFNHL
CCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEECCEEEEEEEEECCCCCCCEEEEHHHH
SNLIKLLDHRILVSEEWVIERKNGLVVIEKNGKRLELPENEAVVLDKPNVTAEYIAEWFA
HHHHHHHHCEEEECCCEEEECCCCEEEEECCCCEEECCCCCEEEEECCCCCHHHHHHHHH
ERIAEKAGNNVRKIRVKIWEDPRSYAEVTLER
HHHHHHHCCCEEEEEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9679194 [H]